RAB6B

Functionⁱ

Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.1 Publication

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Binding siteⁱ	45	GTP		1

Regions

Feature key	Position(s)	DescriptionActions	Length
Nucleotide bindingⁱ	20 – 27	GTP	8
Nucleotide bindingⁱ	68 – 72	GTP	5
Nucleotide bindingⁱ	126 – 129	GTP	4

GO - Molecular functionⁱ

GTPase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
GTP binding Source: UniProtKB-KW
myosin V binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 24006491

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

intracellular protein transport
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
intra-Golgi vesicle-mediated transport
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
Rab protein signal transduction
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
retrograde transport, endosome to Golgi
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
retrograde vesicle-mediated transport, Golgi to ER
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	ER-Golgi transport, Protein transport, Transport
Ligand	GTP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network R-HSA-8854214 TBC/RABGAPs R-HSA-8873719 RAB geranylgeranylation R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs

Reactomeⁱ

R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic
R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network
R-HSA-8854214 TBC/RABGAPs
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ras-related protein Rab-6B
Gene namesⁱ	Name:RAB6B
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 3

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000154917.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:14902 RAB6B
MIMⁱ	615852 gene
neXtProtⁱ	NX_Q9NRW1

Keywords - Cellular componentⁱ

Cytoplasmic vesicle, Golgi apparatus, Membrane

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	27	T → N: Loss of APBA1-binding. 1 Publication		1
Mutagenesisⁱ	72	Q → L: Interacts with APBA1. 1 Publication		1

Organism-specific databases

DisGeNET More...DisGeNETⁱ	51560
Open Targets More...OpenTargetsⁱ	ENSG00000154917
PharmGKBⁱ	PA34147

Polymorphism and mutation databases

BioMutaⁱ	RAB6B
DMDMⁱ	13633595

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000121115	1 – 208	Ras-related protein Rab-6BAdd BLAST		208

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	82	O-AMP-tyrosine; by Legionella DrrA1 Publication	1
Lipidationⁱ	206	S-geranylgeranyl cysteineBy similarity	1
Modified residueⁱ	208	Cysteine methyl esterBy similarity	1
Lipidationⁱ	208	S-geranylgeranyl cysteineBy similarity	1

Keywords - PTMⁱ

Lipoprotein, Methylation, Phosphoprotein, Prenylation

Proteomic databases

EPDⁱ	Q9NRW1
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9NRW1
PaxDbⁱ	Q9NRW1
PeptideAtlas More...PeptideAtlasⁱ	Q9NRW1
PRIDEⁱ	Q9NRW1
ProteomicsDBⁱ	82427

PTM databases

iPTMnetⁱ	Q9NRW1
PhosphoSitePlusⁱ	Q9NRW1
SwissPalmⁱ	Q9NRW1

Expressionⁱ

Tissue specificityⁱ

Predominantly expressed in brain.

Gene expression databases

Bgeeⁱ	ENSG00000154917 Expressed in 192 organ(s), highest expression level in frontal cortex
ExpressionAtlasⁱ	Q9NRW1 baseline and differential
Genevisibleⁱ	Q9NRW1 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB017713 HPA059131

HPAⁱ

CAB017713
HPA059131

Interactionⁱ

Subunit structureⁱ

Interacts with BICDL1/BICDR1; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with RAB6KIFL. Interacts (GTP-bound) with BICD1 (via C-terminus); the interaction is direct. Interacts (GDP-bound) with DYNLRB1. Interacts (GTP-bound) with APBA1/MINT1 isoform 2, also called Mint1_826, but not with isoform 1.By similarity3 Publications

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
APBA1	Q02410-2	4	EBI-1760079,EBI-9247455
COG6	Q9Y2V7	4	EBI-1760079,EBI-3866319

GO - Molecular functionⁱ

myosin V binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 24006491

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	119610, 50 interactors
IntActⁱ	Q9NRW1, 12 interactors
STRINGⁱ	9606.ENSP00000285208

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	15 – 19	Combined sources	5
Helixⁱ	26 – 35	Combined sources	10
Beta strandⁱ	47 – 57	Combined sources	11
Beta strandⁱ	60 – 69	Combined sources	10
Helixⁱ	73 – 78	Combined sources	6
Helixⁱ	79 – 84	Combined sources	6
Beta strandⁱ	87 – 94	Combined sources	8
Helixⁱ	98 – 102	Combined sources	5
Helixⁱ	104 – 115	Combined sources	12
Beta strandⁱ	118 – 126	Combined sources	9
Helixⁱ	131 – 133	Combined sources	3
Helixⁱ	138 – 147	Combined sources	10
Beta strandⁱ	151 – 154	Combined sources	4
Turnⁱ	157 – 159	Combined sources	3
Helixⁱ	163 – 174	Combined sources	12

Show more details

3D structure databases

ProteinModelPortalⁱ	Q9NRW1
SMRⁱ	Q9NRW1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q9NRW1

EvolutionaryTraceⁱ

Q9NRW1

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	42 – 50	Effector regionBy similarity		9

Sequence similaritiesⁱ

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0094 Eukaryota ENOG410XPBI LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000144073
HOGENOMⁱ	HOG000233968
HOVERGENⁱ	HBG009351
InParanoidⁱ	Q9NRW1
KEGG Orthology (KO) More...KOⁱ	K07894
OMAⁱ	KIGHALP
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ORZ
PhylomeDBⁱ	Q9NRW1
TreeFamⁱ	TF300803

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR001806 Small_GTPase
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071 Ras, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS51419 RAB, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9NRW1-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF 
        60         70         80         90        100
LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS 
       110        120        130        140        150
FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV 
       160        170        180        190        200
MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP 

ASEGGCSC

Length:208

Mass (Da):23,462

Last modified:October 1, 2000 - v1

Checksum:ⁱE81C831996E2446D

GO

Isoform 2 (identifier: Q9NRW1-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-24: MSAGGDFGNPLRKFKLVFLGEQSV → MWHMTRNWPLV

« Hide

        10         20         30         40         50
MWHMTRNWPL VGKTSLITRF MYDSFDNTYQ ATIGIDFLSK TMYLEDRTVR 
        60         70         80         90        100
LQLWDTAGQE RFRSLIPSYI RDSTVAVVVY DITNLNSFQQ TSKWIDDVRT 
       110        120        130        140        150
ERGSDVIIML VGNKTDLADK RQITIEEGEQ RAKELSVMFI ETSAKTGYNV 
       160        170        180        190 
KQLFRRVASA LPGMENVQEK SKEGMIDIKL DKPQEPPASE GGCSC

Note: No experimental confirmation available.

Show »

Length:195

Mass (Da):22,334

Checksum:ⁱE772D44D7E9D2C2C

GO

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

C9JU14	C9JU14_HUMAN	Ras-related protein Rab-6B Ras-related protein Rab-6B	RAB6B	83	Annotation score:
J3KR73	J3KR73_HUMAN	Ras-related protein Rab-6B Ras-related protein Rab-6B	RAB6B	124	Annotation score:
C9JB90	C9JB90_HUMAN	Ras-related protein Rab-6B Ras-related protein Rab-6B	RAB6B	49	Annotation score:
C9J0I2	C9J0I2_HUMAN	Ras-related protein Rab-6B Ras-related protein Rab-6B	RAB6B	71	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_055831	1 – 24	MSAGG…GEQSV → MWHMTRNWPLV in isoform 2. 1 PublicationAdd BLAST		24

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF166492 mRNA Translation: AAF61637.1 AF498940 mRNA Translation: AAM21088.1 BT007263 mRNA Translation: AAP35927.1 AK295451 mRNA Translation: BAH12073.1 AK312378 mRNA Translation: BAG35296.1 AC080128 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW79158.1 CH471052 Genomic DNA Translation: EAW79159.1 BC002510 mRNA Translation: AAH02510.1 U66623 mRNA Translation: AAC51198.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS3082.1 [Q9NRW1-1] CCDS87137.1 [Q9NRW1-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_057661.3, NM_016577.3 [Q9NRW1-1] XP_011511195.1, XM_011512893.2
UniGeneⁱ	Hs.715344

Genome annotation databases

Ensemblⁱ	ENST00000285208; ENSP00000285208; ENSG00000154917 [Q9NRW1-1] ENST00000486858; ENSP00000419381; ENSG00000154917 [Q9NRW1-2] ENST00000543906; ENSP00000437797; ENSG00000154917 [Q9NRW1-1]
GeneIDⁱ	51560
KEGGⁱ	hsa:51560
UCSC genome browser More...UCSCⁱ	uc003epy.4 human [Q9NRW1-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9NRW1	Ras-related protein Rab-6B		BOVIN		208	UniRef100_Q9NRW1
Ras-related protein Rab-6B		MOUSE		208
Uncharacterized protein		CALJA		425
Ras-related protein Rab-6B (Fragment)		HUMAN		124
RAB6B isoform 5 (Fragment)		PONAB		124
+52
Q9NRW1-2	RAB6B isoform 4		PANTR		195	UniRef100_A0A2I3RQZ5
Uncharacterized protein		MACMU		195
RAB6B isoform 6		PONAB		195
Uncharacterized protein		PAPAN		195
Uncharacterized protein		PANPA		195
+3

Protein	Similar proteins		Species	Score	Length	Source
Q9NRW1	Ras-related protein Rab-6B		BOVIN		208	UniRef90_Q9NRW1
Ras-related protein Rab-6B		MOUSE		208
Uncharacterized protein		CALJA		425
Ras-related protein Rab-6B (Fragment)		HUMAN		124
RAB6B isoform 5 (Fragment)		PONAB		124
+52
Q9NRW1-2	Uncharacterized protein		FELCA		196	UniRef90_M3WBQ7
Uncharacterized protein		COLAP		195
Uncharacterized protein		RHIRO		195
Uncharacterized protein		RHIBE		195
Uncharacterized protein		MANLE		195
+20

Protein	Similar proteins		Species	Score	Length	Source
Q9NRW1	Ras-related protein Rab-6B		BOVIN		208	UniRef50_Q9NRW1
Ras-related protein Rab-6B		MOUSE		208
Uncharacterized protein		CALJA		425
Ras-related protein Rab-6B (Fragment)		HUMAN		124
RAB6B isoform 5 (Fragment)		PONAB		124
+61
Q9NRW1-2	Uncharacterized protein		MACMU		188	UniRef50_F7A091
Uncharacterized protein		Cebus capucinus imitator		198
Uncharacterized protein		CALJA		194
Uncharacterized protein		PIG		192
Uncharacterized protein		CAVPO		192
+70

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF166492 mRNA Translation: AAF61637.1 AF498940 mRNA Translation: AAM21088.1 BT007263 mRNA Translation: AAP35927.1 AK295451 mRNA Translation: BAH12073.1 AK312378 mRNA Translation: BAG35296.1 AC080128 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW79158.1 CH471052 Genomic DNA Translation: EAW79159.1 BC002510 mRNA Translation: AAH02510.1 U66623 mRNA Translation: AAC51198.1
CCDSⁱ	CCDS3082.1 [Q9NRW1-1] CCDS87137.1 [Q9NRW1-2]
RefSeqⁱ	NP_057661.3, NM_016577.3 [Q9NRW1-1] XP_011511195.1, XM_011512893.2
UniGeneⁱ	Hs.715344

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2E9S	X-ray	1.78	A/B/C	13-174	[»]
	2FE4	X-ray	2.30	A	13-174	[»]
	2FFQ	X-ray	1.78	A	13-174	[»]
ProteinModelPortalⁱ	Q9NRW1
SMRⁱ	Q9NRW1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	119610, 50 interactors
IntActⁱ	Q9NRW1, 12 interactors
STRINGⁱ	9606.ENSP00000285208

PTM databases

iPTMnetⁱ	Q9NRW1
PhosphoSitePlusⁱ	Q9NRW1
SwissPalmⁱ	Q9NRW1

Polymorphism and mutation databases

BioMutaⁱ	RAB6B
DMDMⁱ	13633595

Proteomic databases

EPDⁱ	Q9NRW1
MaxQBⁱ	Q9NRW1
PaxDbⁱ	Q9NRW1
PeptideAtlasⁱ	Q9NRW1
PRIDEⁱ	Q9NRW1
ProteomicsDBⁱ	82427

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	51560
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000285208; ENSP00000285208; ENSG00000154917 [Q9NRW1-1] ENST00000486858; ENSP00000419381; ENSG00000154917 [Q9NRW1-2] ENST00000543906; ENSP00000437797; ENSG00000154917 [Q9NRW1-1]
GeneIDⁱ	51560
KEGGⁱ	hsa:51560
UCSCⁱ	uc003epy.4 human [Q9NRW1-1]

Organism-specific databases

CTDⁱ	51560
DisGeNETⁱ	51560
EuPathDBⁱ	HostDB:ENSG00000154917.10
GeneCardsⁱ	RAB6B
HGNCⁱ	HGNC:14902 RAB6B
HPAⁱ	CAB017713 HPA059131
MIMⁱ	615852 gene
neXtProtⁱ	NX_Q9NRW1
OpenTargetsⁱ	ENSG00000154917
PharmGKBⁱ	PA34147
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0094 Eukaryota ENOG410XPBI LUCA
GeneTreeⁱ	ENSGT00910000144073
HOGENOMⁱ	HOG000233968
HOVERGENⁱ	HBG009351
InParanoidⁱ	Q9NRW1
KOⁱ	K07894
OMAⁱ	KIGHALP
OrthoDBⁱ	EOG091G0ORZ
PhylomeDBⁱ	Q9NRW1
TreeFamⁱ	TF300803

Enzyme and pathway databases

Reactomeⁱ	R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network R-HSA-8854214 TBC/RABGAPs R-HSA-8873719 RAB geranylgeranylation R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs

Reactomeⁱ

R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic
R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network
R-HSA-8854214 TBC/RABGAPs
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

ChiTaRSⁱ	RAB6B human
EvolutionaryTraceⁱ	Q9NRW1
GeneWikiⁱ	RAB6B
GenomeRNAiⁱ	51560
Protein Ontology More...PROⁱ	PR:Q9NRW1
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000154917 Expressed in 192 organ(s), highest expression level in frontal cortex
ExpressionAtlasⁱ	Q9NRW1 baseline and differential
Genevisibleⁱ	Q9NRW1 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR001806 Small_GTPase
Pfamⁱ	View protein in Pfam PF00071 Ras, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS51419 RAB, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RAB6B_HUMAN
Accessionⁱ	Q9NRW1Primary (citable) accession number: Q9NRW1 Secondary accession number(s): B2R5Z9 , B7Z337, D3DND3, Q92929
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
	Last sequence update:	October 1, 2000
	Last modified:	November 7, 2018
	This is version 180 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

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UniProtKB - Q9NRW1 (RAB6B_HUMAN)

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Ras-related protein Rab-6B

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Golgi apparatus

Other locations

Cytosol

Golgi apparatus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ