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Entry version 109 (26 Feb 2020)
Sequence version 1 (01 Oct 2000)
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Protein

COX assembly mitochondrial protein 2 homolog

Gene

CMC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in cytochrome c oxidase biogenesis.By similarity

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1268020 Mitochondrial protein import

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
COX assembly mitochondrial protein 2 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CMC2
Synonyms:C16orf61
ORF Names:DC13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24447 CMC2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NRP2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
56942

Open Targets

More...
OpenTargetsi
ENSG00000103121

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485398

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NRP2 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CMC2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
37999796

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001929431 – 79COX assembly mitochondrial protein 2 homologAdd BLAST79

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi14 ↔ 47PROSITE-ProRule annotation
Disulfide bondi24 ↔ 37PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NRP2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NRP2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NRP2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NRP2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NRP2

PeptideAtlas

More...
PeptideAtlasi
Q9NRP2

PRoteomics IDEntifications database

More...
PRIDEi
Q9NRP2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82399

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q9NRP2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NRP2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NRP2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000103121 Expressed in oocyte and 228 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NRP2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NRP2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB026396
HPA006871

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121266, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NRP2, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000219400

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NRP2 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini11 – 55CHCHPROSITE-ProRule annotationAdd BLAST45

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi14 – 24Cx9C motif 1PROSITE-ProRule annotationAdd BLAST11
Motifi37 – 47Cx9C motif 2PROSITE-ProRule annotationAdd BLAST11

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CMC family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4148 Eukaryota
ENOG41123JB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016908

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_169286_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NRP2

KEGG Orthology (KO)

More...
KOi
K18172

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHKEHNV

Database of Orthologous Groups

More...
OrthoDBi
1546992at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NRP2

TreeFam database of animal gene trees

More...
TreeFami
TF314049

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013892 Cyt_c_biogenesis_Cmc1-like

The PANTHER Classification System

More...
PANTHERi
PTHR22977 PTHR22977, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08583 Cmc1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51808 CHCH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

Q9NRP2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHPDLSPHLH TEECNVLINL LKECHKNHNI LKFFGYCNDV DRELRKCLKN
60 70
EYVENRTKSR EHGIAMRKKL FNPPEESEK
Length:79
Mass (Da):9,460
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i783381BD6DAFB7AA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BNN8H3BNN8_HUMAN
COX assembly mitochondrial protein
CMC2 C16orf61, hCG_1641210
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTB6H3BTB6_HUMAN
COX assembly mitochondrial protein
CMC2 C16orf61, hCG_1641210
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPP2H3BPP2_HUMAN
COX assembly mitochondrial protein
CMC2
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQQ1H3BQQ1_HUMAN
COX assembly mitochondrial protein
CMC2
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BRC3H3BRC3_HUMAN
COX assembly mitochondrial protein
CMC2
50Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BN28H3BN28_HUMAN
COX assembly mitochondrial protein
CMC2
36Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BP68H3BP68_HUMAN
COX assembly mitochondrial protein
CMC2
51Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03381611T → S. Corresponds to variant dbSNP:rs2303217Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF201935 mRNA Translation: AAF86871.1
AC009079 Genomic DNA No translation available.
AC092718 Genomic DNA No translation available.
CH471114 Genomic DNA Translation: EAW95557.1
CH471114 Genomic DNA Translation: EAW95559.1
CH471114 Genomic DNA Translation: EAW95560.1
BC032631 mRNA Translation: AAH32631.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10930.1

NCBI Reference Sequences

More...
RefSeqi
NP_064573.1, NM_020188.3
XP_016878956.1, XM_017023467.1
XP_016878957.1, XM_017023468.1
XP_016878958.1, XM_017023469.1
XP_016878959.1, XM_017023470.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000219400; ENSP00000219400; ENSG00000103121
ENST00000564249; ENSP00000456841; ENSG00000103121
ENST00000565650; ENSP00000455457; ENSG00000103121
ENST00000565914; ENSP00000455723; ENSG00000103121

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56942

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:56942

UCSC genome browser

More...
UCSCi
uc002ffu.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF201935 mRNA Translation: AAF86871.1
AC009079 Genomic DNA No translation available.
AC092718 Genomic DNA No translation available.
CH471114 Genomic DNA Translation: EAW95557.1
CH471114 Genomic DNA Translation: EAW95559.1
CH471114 Genomic DNA Translation: EAW95560.1
BC032631 mRNA Translation: AAH32631.1
CCDSiCCDS10930.1
RefSeqiNP_064573.1, NM_020188.3
XP_016878956.1, XM_017023467.1
XP_016878957.1, XM_017023468.1
XP_016878958.1, XM_017023469.1
XP_016878959.1, XM_017023470.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi121266, 9 interactors
IntActiQ9NRP2, 8 interactors
STRINGi9606.ENSP00000219400

PTM databases

iPTMnetiQ9NRP2
PhosphoSitePlusiQ9NRP2

Polymorphism and mutation databases

BioMutaiCMC2
DMDMi37999796

Proteomic databases

EPDiQ9NRP2
jPOSTiQ9NRP2
MassIVEiQ9NRP2
MaxQBiQ9NRP2
PaxDbiQ9NRP2
PeptideAtlasiQ9NRP2
PRIDEiQ9NRP2
ProteomicsDBi82399
TopDownProteomicsiQ9NRP2

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
56942

Genome annotation databases

EnsembliENST00000219400; ENSP00000219400; ENSG00000103121
ENST00000564249; ENSP00000456841; ENSG00000103121
ENST00000565650; ENSP00000455457; ENSG00000103121
ENST00000565914; ENSP00000455723; ENSG00000103121
GeneIDi56942
KEGGihsa:56942
UCSCiuc002ffu.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56942
DisGeNETi56942

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CMC2
HGNCiHGNC:24447 CMC2
HPAiCAB026396
HPA006871
neXtProtiNX_Q9NRP2
OpenTargetsiENSG00000103121
PharmGKBiPA143485398

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4148 Eukaryota
ENOG41123JB LUCA
GeneTreeiENSGT00390000016908
HOGENOMiCLU_169286_2_0_1
InParanoidiQ9NRP2
KOiK18172
OMAiCHKEHNV
OrthoDBi1546992at2759
PhylomeDBiQ9NRP2
TreeFamiTF314049

Enzyme and pathway databases

ReactomeiR-HSA-1268020 Mitochondrial protein import

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CMC2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
56942
PharosiQ9NRP2 Tbio

Protein Ontology

More...
PROi
PR:Q9NRP2
RNActiQ9NRP2 protein

Gene expression databases

BgeeiENSG00000103121 Expressed in oocyte and 228 other tissues
ExpressionAtlasiQ9NRP2 baseline and differential
GenevisibleiQ9NRP2 HS

Family and domain databases

InterProiView protein in InterPro
IPR013892 Cyt_c_biogenesis_Cmc1-like
PANTHERiPTHR22977 PTHR22977, 1 hit
PfamiView protein in Pfam
PF08583 Cmc1, 1 hit
PROSITEiView protein in PROSITE
PS51808 CHCH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOXM2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NRP2
Secondary accession number(s): D3DUK6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: October 1, 2000
Last modified: February 26, 2020
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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