Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - Q9NRN5 (OLFL3_HUMAN)

Entry version 156 (23 Feb 2022)
Sequence version 1 (01 Oct 2000)
Previous versions | rss
Add a publicationFeedback
Protein

Olfactomedin-like protein 3

Gene

OLFML3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity).

May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.

By similarity1 Publication

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9NRN5

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9NRN5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Olfactomedin-like protein 3
Alternative name(s):
HNOEL-iso
hOLF44
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OLFML3
ORF Names:PSEC0035, PSEC0173, PSEC0244, UNQ663/PRO1294
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24956, OLFML3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		610088, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NRN5

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000116774

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		56944

Open Targets

More...OpenTargetsi		ENSG00000116774

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134913777

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9NRN5, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		OLFML3

Domain mapping of disease mutations (DMDM)

More...DMDMi		37999795

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002009222 – 406Olfactomedin-like protein 3Add BLAST385

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi135 ↔ 328PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi177N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi248N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NRN5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9NRN5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NRN5

PeptideAtlas

More...PeptideAtlasi		Q9NRN5

PRoteomics IDEntifications database

More...PRIDEi		Q9NRN5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		82393 [Q9NRN5-1]
82394 [Q9NRN5-2]
82395 [Q9NRN5-3]

PTM databases

GlyConnect protein glycosylation platform

More...GlyConnecti		1587, 52 N-Linked glycans (2 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9NRN5, 2 sites, 55 N-linked glycans (2 sites)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NRN5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NRN5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000116774, Expressed in ectocervix and 119 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NRN5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NRN5, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000116774, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		121268, 11 interactors

Protein interaction database and analysis system

More...IntActi		Q9NRN5, 7 interactors

Molecular INTeraction database

More...MINTi		Q9NRN5

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000322273

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9NRN5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NRN5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini134 – 401Olfactomedin-likePROSITE-ProRule annotationAdd BLAST268

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili25 – 101Sequence analysisAdd BLAST77

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the OLFML3 family.Curated

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3545, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158083

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NRN5

Identification of Orthologs from Complete Genome Data

More...OMAi		EQLLYAW

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NRN5

TreeFam database of animal gene trees

More...TreeFami		TF352000

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003112, Olfac-like_dom
IPR031230, OLFML3

The PANTHER Classification System

More...PANTHERi		PTHR23192:SF8, PTHR23192:SF8, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02191, OLF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00284, OLF, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51132, OLF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NRN5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGPSTPLLIL FLLSWSGPLQ GQQHHLVEYM ERRLAALEER LAQCQDQSSR 
        60         70         80         90        100
HAAELRDFKN KMLPLLEVAE KEREALRTEA DTISGRVDRL EREVDYLETQ 
       110        120        130        140        150
NPALPCVEFD EKVTGGPGTK GKGRRNEKYD MVTDCGYTIS QVRSMKILKR 
       160        170        180        190        200
FGGPAGLWTK DPLGQTEKIY VLDGTQNDTA FVFPRLRDFT LAMAARKASR 
       210        220        230        240        250
VRVPFPWVGT GQLVYGGFLY FARRPPGRPG GGGEMENTLQ LIKFHLANRT 
       260        270        280        290        300
VVDSSVFPAE GLIPPYGLTA DTYIDLAADE EGLWAVYATR EDDRHLCLAK 
       310        320        330        340        350
LDPQTLDTEQ QWDTPCPREN AEAAFVICGT LYVVYNTRPA SRARIQCSFD 
       360        370        380        390        400
ASGTLTPERA ALPYFPRRYG AHASLRYNPR ERQLYAWDDG YQIVYKLEMR 

KKEEEV
Length:406
Mass (Da):46,010
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0B5DB1A803BB99D6
GO
Isoform 2 (identifier: Q9NRN5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-20: Missing.
     21-38: GQQHHLVEYMERRLAALE → MAQWHCSQRTQAGGHGVG

Show »
Length:386
Mass (Da):43,588
Checksum:iACCD914542650DBD
GO
Isoform 3 (identifier: Q9NRN5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     134-287: DCGYTISQVR...ADEEGLWAVY → GKQSESRPLT...EDLRVRWDTE
     288-406: Missing.

Show »
Length:287
Mass (Da):32,451
Checksum:iE5FA3E724F51D55B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DNG0B4DNG0_HUMAN
Olfactomedin-like protein 3
OLFML3
345Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti118G → E in BAD96191 (Ref. 5) Curated1
Sequence conflicti131M → K in BAD96941 (Ref. 5) Curated1
Sequence conflicti182V → F in BAD96191 (Ref. 5) Curated1
Sequence conflicti277A → V in AAQ89313 (PubMed:12975309).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0141281 – 20Missing in isoform 2. CuratedAdd BLAST20
Alternative sequenceiVSP_01412921 – 38GQQHH…LAALE → MAQWHCSQRTQAGGHGVG in isoform 2. CuratedAdd BLAST18
Alternative sequenceiVSP_014130134 – 287DCGYT…LWAVY → GKQSESRPLTLLRTDILPSL LLTLFFTLSQSIVALSSGIC FRETSVMPGLLRRGSGDPGR CGTRSFSILPKIGGNRWANA HYSPDHPPWGSSCWRHLILA SISFSCAFLIRLWLHNLSSE INEDSEAIWWPSWSMDQGST GANREDLRVRWDTE in isoform 3. 1 PublicationAdd BLAST154
Alternative sequenceiVSP_014131288 – 406Missing in isoform 3. 1 PublicationAdd BLAST119

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY464015 mRNA Translation: AAR88262.1
AF201945 mRNA Translation: AAF86881.1
AY358954 mRNA Translation: AAQ89313.1
AK075544 mRNA Translation: BAC11687.1
AK223221 mRNA Translation: BAD96941.1
AK222471 mRNA Translation: BAD96191.1
AK075353 mRNA Translation: BAC11564.1
AK075479 mRNA Translation: BAC11644.1
AL731797 Genomic DNA No translation available.
BC009920 mRNA Translation: AAH09920.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS65618.1 [Q9NRN5-2]
CCDS870.1 [Q9NRN5-1]

NCBI Reference Sequences

More...RefSeqi		NP_001273281.1, NM_001286352.2 [Q9NRN5-2]
NP_064575.1, NM_020190.4 [Q9NRN5-1]
XP_016857337.1, XM_017001848.1 [Q9NRN5-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000320334; ENSP00000322273; ENSG00000116774
ENST00000369551; ENSP00000358564; ENSG00000116774 [Q9NRN5-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		56944

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:56944

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000320334.5; ENSP00000322273.4; NM_020190.5; NP_064575.1

UCSC genome browser

More...UCSCi		uc001eer.3, human [Q9NRN5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY464015 mRNA Translation: AAR88262.1
AF201945 mRNA Translation: AAF86881.1
AY358954 mRNA Translation: AAQ89313.1
AK075544 mRNA Translation: BAC11687.1
AK223221 mRNA Translation: BAD96941.1
AK222471 mRNA Translation: BAD96191.1
AK075353 mRNA Translation: BAC11564.1
AK075479 mRNA Translation: BAC11644.1
AL731797 Genomic DNA No translation available.
BC009920 mRNA Translation: AAH09920.1
CCDSiCCDS65618.1 [Q9NRN5-2]
CCDS870.1 [Q9NRN5-1]
RefSeqiNP_001273281.1, NM_001286352.2 [Q9NRN5-2]
NP_064575.1, NM_020190.4 [Q9NRN5-1]
XP_016857337.1, XM_017001848.1 [Q9NRN5-2]

3D structure databases

SMRiQ9NRN5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi121268, 11 interactors
IntActiQ9NRN5, 7 interactors
MINTiQ9NRN5
STRINGi9606.ENSP00000322273

PTM databases

GlyConnecti1587, 52 N-Linked glycans (2 sites)
GlyGeniQ9NRN5, 2 sites, 55 N-linked glycans (2 sites)
iPTMnetiQ9NRN5
PhosphoSitePlusiQ9NRN5

Genetic variation databases

BioMutaiOLFML3
DMDMi37999795

Proteomic databases

jPOSTiQ9NRN5
MassIVEiQ9NRN5
PaxDbiQ9NRN5
PeptideAtlasiQ9NRN5
PRIDEiQ9NRN5
ProteomicsDBi82393 [Q9NRN5-1]
82394 [Q9NRN5-2]
82395 [Q9NRN5-3]

Protocols and materials databases

ABCD curated depository of sequenced antibodies

More...ABCDi		Q9NRN5, 3 sequenced antibodies

Antibodypedia a portal for validated antibodies

More...Antibodypediai		53757, 79 antibodies from 20 providers

The DNASU plasmid repository

More...DNASUi		56944

Genome annotation databases

EnsembliENST00000320334; ENSP00000322273; ENSG00000116774
ENST00000369551; ENSP00000358564; ENSG00000116774 [Q9NRN5-2]
GeneIDi56944
KEGGihsa:56944
MANE-SelectiENST00000320334.5; ENSP00000322273.4; NM_020190.5; NP_064575.1
UCSCiuc001eer.3, human [Q9NRN5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		56944
DisGeNETi56944

GeneCards: human genes, protein and diseases

More...GeneCardsi		OLFML3
HGNCiHGNC:24956, OLFML3
HPAiENSG00000116774, Low tissue specificity
MIMi610088, gene
neXtProtiNX_Q9NRN5
OpenTargetsiENSG00000116774
PharmGKBiPA134913777
VEuPathDBiHostDB:ENSG00000116774

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3545, Eukaryota
GeneTreeiENSGT00940000158083
InParanoidiQ9NRN5
OMAiEQLLYAW
PhylomeDBiQ9NRN5
TreeFamiTF352000

Enzyme and pathway databases

PathwayCommonsiQ9NRN5
SignaLinkiQ9NRN5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		56944, 230 hits in 1031 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		OLFML3, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		OLFML3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		56944
PharosiQ9NRN5, Tbio

Protein Ontology

More...PROi		PR:Q9NRN5
RNActiQ9NRN5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000116774, Expressed in ectocervix and 119 other tissues
ExpressionAtlasiQ9NRN5, baseline and differential
GenevisibleiQ9NRN5, HS

Family and domain databases

InterProiView protein in InterPro
IPR003112, Olfac-like_dom
IPR031230, OLFML3
PANTHERiPTHR23192:SF8, PTHR23192:SF8, 1 hit
PfamiView protein in Pfam
PF02191, OLF, 1 hit
SMARTiView protein in SMART
SM00284, OLF, 1 hit
PROSITEiView protein in PROSITE
PS51132, OLF, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOLFL3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NRN5
Secondary accession number(s): Q53FR1
, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: October 1, 2000
Last modified: February 23, 2022
This is version 156 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again