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Entry version 154 (12 Aug 2020)
Sequence version 2 (07 Jul 2009)
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Protein

Zinc finger protein 277

Gene

ZNF277

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri224 – 248C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri355 – 381C2H2-type 2PROSITE-ProRule annotationAdd BLAST27

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NRM2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 277
Alternative name(s):
Nuclear receptor-interacting factor 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF277
Synonyms:NRIF4, ZNF277P
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000198839.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13070, ZNF277

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605465, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NRM2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
11179

Open Targets

More...
OpenTargetsi
ENSG00000198839

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37646

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NRM2, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF277

Domain mapping of disease mutations (DMDM)

More...
DMDMi
251757417

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475032 – 450Zinc finger protein 277Add BLAST449

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NRM2

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9NRM2

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9NRM2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NRM2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NRM2

PeptideAtlas

More...
PeptideAtlasi
Q9NRM2

PRoteomics IDEntifications database

More...
PRIDEi
Q9NRM2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82389

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NRM2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NRM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198839, Expressed in calcaneal tendon and 223 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NRM2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NRM2, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000198839, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
116349, 16 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NRM2, 20 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000354501

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NRM2, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ZNF277 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri224 – 248C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri355 – 381C2H2-type 2PROSITE-ProRule annotationAdd BLAST27

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2482, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010852

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_033436_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NRM2

Identification of Orthologs from Complete Genome Data

More...
OMAi
DQPEYYF

Database of Orthologous Groups

More...
OrthoDBi
1498904at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NRM2

TreeFam database of animal gene trees

More...
TreeFami
TF318036

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041661, ZN622/Rei1/Reh1_Znf-C2H2
IPR040048, ZNF277
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR13267, PTHR13267, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12756, zf-C2H2_2, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 2 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q9NRM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASKTQGAV ARMQEDRDGS CSTVGGVGYG DSKDCILEPL SLPESPGGTT
60 70 80 90 100
TLEGSPSVPC IFCEEHFPVA EQDKLLKHMI IEHKIVIADV KLVADFQRYI
110 120 130 140 150
LYWRKRFTEQ PITDFCSVIR INSTAPFEEQ ENYFLLCDVL PEDRILREEL
160 170 180 190 200
QKQRLREILE QQQQERNDTN FHGVCMFCNE EFLGNRSVIL NHMAREHAFN
210 220 230 240 250
IGLPDNIVNC NEFLCTLQKK LDNLQCLYCE KTFRDKNTLK DHMRKKQHRK
260 270 280 290 300
INPKNREYDR FYVINYLELG KSWEEVQLED DRELLDHQED DWSDWEEHPA
310 320 330 340 350
SAVCLFCEKQ AETIEKLYVH MEDAHEFDLL KIKSELGLNF YQQVKLVNFI
360 370 380 390 400
RRQVHQCRCY GCHVKFKSKA DLRTHMEETK HTSLLPDRKT WDQLEYYFPT
410 420 430 440 450
YENDTLLCTL SDSESDLTAQ EQNENVPIIS EDTSKLYALK QSSILNQLLL
Length:450
Mass (Da):52,788
Last modified:July 7, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i07A35E08BB6E9521
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E9M4G5E9M4_HUMAN
Zinc finger protein 277
ZNF277 hCG_14753
290Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J3B6C9J3B6_HUMAN
Zinc finger protein 277
ZNF277
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JH62C9JH62_HUMAN
Zinc finger protein 277
ZNF277
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C460H7C460_HUMAN
Zinc finger protein 277
ZNF277
118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WBE4F8WBE4_HUMAN
Zinc finger protein 277
ZNF277
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EW13E7EW13_HUMAN
Zinc finger protein 277
ZNF277
50Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF85941 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAS07413 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_059908174V → I. Corresponds to variant dbSNP:rs34571830Ensembl.1
Natural variantiVAR_035574332I → L in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_057415364V → M. Corresponds to variant dbSNP:rs11539696Ensembl.1
Natural variantiVAR_035575445L → F in a breast cancer sample; somatic mutation. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF209198 mRNA Translation: AAF85941.1 Different initiation.
AF308819 mRNA Translation: AAL55819.1
AC004112 Genomic DNA Translation: AAS07407.1
AC004111 Genomic DNA Translation: AAS07413.1 Different initiation.
CH471070 Genomic DNA Translation: EAW83461.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5755.2

NCBI Reference Sequences

More...
RefSeqi
NP_068834.2, NM_021994.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361822; ENSP00000354501; ENSG00000198839

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11179

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:11179

UCSC genome browser

More...
UCSCi
uc003vge.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF209198 mRNA Translation: AAF85941.1 Different initiation.
AF308819 mRNA Translation: AAL55819.1
AC004112 Genomic DNA Translation: AAS07407.1
AC004111 Genomic DNA Translation: AAS07413.1 Different initiation.
CH471070 Genomic DNA Translation: EAW83461.1
CCDSiCCDS5755.2
RefSeqiNP_068834.2, NM_021994.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi116349, 16 interactors
IntActiQ9NRM2, 20 interactors
STRINGi9606.ENSP00000354501

PTM databases

iPTMnetiQ9NRM2
PhosphoSitePlusiQ9NRM2

Polymorphism and mutation databases

BioMutaiZNF277
DMDMi251757417

Proteomic databases

EPDiQ9NRM2
jPOSTiQ9NRM2
MassIVEiQ9NRM2
MaxQBiQ9NRM2
PaxDbiQ9NRM2
PeptideAtlasiQ9NRM2
PRIDEiQ9NRM2
ProteomicsDBi82389

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
17357, 106 antibodies

Genome annotation databases

EnsembliENST00000361822; ENSP00000354501; ENSG00000198839
GeneIDi11179
KEGGihsa:11179
UCSCiuc003vge.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
11179
DisGeNETi11179
EuPathDBiHostDB:ENSG00000198839.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF277
HGNCiHGNC:13070, ZNF277
HPAiENSG00000198839, Low tissue specificity
MIMi605465, gene
neXtProtiNX_Q9NRM2
OpenTargetsiENSG00000198839
PharmGKBiPA37646

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2482, Eukaryota
GeneTreeiENSGT00390000010852
HOGENOMiCLU_033436_0_0_1
InParanoidiQ9NRM2
OMAiDQPEYYF
OrthoDBi1498904at2759
PhylomeDBiQ9NRM2
TreeFamiTF318036

Enzyme and pathway databases

PathwayCommonsiQ9NRM2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
11179, 5 hits in 891 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF277, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
ZNF277P

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
11179
PharosiQ9NRM2, Tbio

Protein Ontology

More...
PROi
PR:Q9NRM2
RNActiQ9NRM2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000198839, Expressed in calcaneal tendon and 223 other tissues
ExpressionAtlasiQ9NRM2, baseline and differential
GenevisibleiQ9NRM2, HS

Family and domain databases

InterProiView protein in InterPro
IPR041661, ZN622/Rei1/Reh1_Znf-C2H2
IPR040048, ZNF277
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PANTHERiPTHR13267, PTHR13267, 1 hit
PfamiView protein in Pfam
PF12756, zf-C2H2_2, 3 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 5 hits
SUPFAMiSSF57667, SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 2 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN277_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NRM2
Secondary accession number(s): Q75MZ2, Q75MZ3, Q8WY14
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: July 7, 2009
Last modified: August 12, 2020
This is version 154 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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