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Entry version 177 (12 Aug 2020)
Sequence version 1 (01 Oct 2000)
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Protein

Suppressor of SWI4 1 homolog

Gene

PPAN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May have a role in cell growth.

Miscellaneous

A chimeric transcript, characterized by the first third of PPAN exon 12 joined to P2RY11 exon 2, has been detected. It is possibly produced by trans-splicing. The chimeric transcript is widely expressed and can be induced by retinoic acid during the granulocytic differentiation of the HL-60 cell line. The resulting chimeric protein shows a much lower activity than the non-chimeric P2RY11 gene product, but qualitatively indistinguishable (PubMed:11278528).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9NQ55

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Suppressor of SWI4 1 homolog
Short name:
Ssf-1
Alternative name(s):
Brix domain-containing protein 3
Peter Pan homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PPAN
Synonyms:BXDC3, SSF1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000130810.19

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9227, PPAN

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
607793, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NQ55

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
56342
692312

Open Targets

More...
OpenTargetsi
ENSG00000130810
ENSG00000243207

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162399971

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NQ55, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PPAN

Domain mapping of disease mutations (DMDM)

More...
DMDMi
21264056

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001202571 – 473Suppressor of SWI4 1 homologAdd BLAST473

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei238PhosphoserineBy similarity1
Modified residuei240PhosphoserineBy similarity1
Modified residuei359PhosphoserineBy similarity1
Modified residuei438N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NQ55

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NQ55

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NQ55

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NQ55

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NQ55

PeptideAtlas

More...
PeptideAtlasi
Q9NQ55

PRoteomics IDEntifications database

More...
PRIDEi
Q9NQ55

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
82082 [Q9NQ55-1]
82083 [Q9NQ55-2]
8341

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
Q9NQ55

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NQ55

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
Q9NQ55

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NQ55

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9NQ55

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000130810, Expressed in sural nerve and 197 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NQ55, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NQ55, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000130810, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121141, 123 interactors
593098, 49 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NQ55, 124 interactors

Molecular INTeraction database

More...
MINTi
Q9NQ55

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000253107

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9NQ55, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 292BrixPROSITE-ProRule annotationAdd BLAST264

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2963, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000064158

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_026936_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NQ55

KEGG Orthology (KO)

More...
KOi
K14859

Identification of Orthologs from Complete Genome Data

More...
OMAi
VTHLMLF

Database of Orthologous Groups

More...
OrthoDBi
353508at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NQ55

TreeFam database of animal gene trees

More...
TreeFami
TF318923

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007109, Brix

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04427, Brix, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00879, Brix, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50833, BRIX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NQ55-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGQSGRSRHQ KRARAQAQLR NLEAYAANPH SFVFTRGCTG RNIRQLSLDV
60 70 80 90 100
RRVMEPLTAS RLQVRKKNSL KDCVAVAGPL GVTHFLILSK TETNVYFKLM
110 120 130 140 150
RLPGGPTLTF QVKKYSLVRD VVSSLRRHRM HEQQFAHPPL LVLNSFGPHG
160 170 180 190 200
MHVKLMATMF QNLFPSINVH KVNLNTIKRC LLIDYNPDSQ ELDFRHYSIK
210 220 230 240 250
VVPVGASRGM KKLLQEKFPN MSRLQDISEL LATGAGLSES EAEPDGDHNI
260 270 280 290 300
TELPQAVAGR GNMRAQQSAV RLTEIGPRMT LQLIKVQEGV GEGKVMFHSF
310 320 330 340 350
VSKTEEELQA ILEAKEKKLR LKAQRQAQQA QNVQRKQEQR EAHRKKSLEG
360 370 380 390 400
MKKARVGGSD EEASGIPSRT ASLELGEDDD EQEDDDIEYF CQAVGEAPSE
410 420 430 440 450
DLFPEAKQKR LAKSPGRKRK RWEMDRGRGR LCDQKFPKTK DKSQGAQARR
460 470
GPRGASRDGG RGRGRGRPGK RVA
Length:473
Mass (Da):53,194
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9FF7B7201BD37BEC
GO
Isoform 2 (identifier: Q9NQ55-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     444-456: Missing.

Show »
Length:460
Mass (Da):51,900
Checksum:iDEDA8FEF86C6575D
GO
Isoform 3 (identifier: Q9NQ55-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     448-473: ARRGPRGASRDGGRGRGRGRPGKRVA → VPSPALPTSW...SWQSATCSAP

Show »
Length:520
Mass (Da):58,199
Checksum:iB5EE1A65E9E13B5E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8MV53A8MV53_HUMAN
HCG2033702, isoform CRA_a
PPAN hCG_2033702
420Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C446H7C446_HUMAN
Suppressor of SWI4 1 homolog
PPAN
208Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J3W3C9J3W3_HUMAN
Suppressor of SWI4 1 homolog
PPAN
210Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JHF7C9JHF7_HUMAN
Suppressor of SWI4 1 homolog
PPAN
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 3 (identifier: Q9NQ55-3)
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti520P → L in BC171852 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_022157358G → V. Corresponds to variant dbSNP:rs2305793Ensembl.1
Natural variantiVAR_048422408Q → R. Corresponds to variant dbSNP:rs11559188Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_003973444 – 456Missing in isoform 2. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_046377448 – 473ARRGP…GKRVA → VPSPALPTSWQLPTTNSVGS RGTSCGPYWWLSSWWPWPAM AWPCTASASGSSAHGTPPWS SLSSWQSATCSAP in isoform 3. 1 PublicationAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ292529 mRNA Translation: CAB99252.1
AC020931 Genomic DNA No translation available.
BC000535 mRNA Translation: AAH00535.2
BC009833 mRNA Translation: AAH09833.1
BC033202 mRNA Translation: AAH33202.1
BC171852 mRNA No translation available.
AJ300588 mRNA Translation: CAC18877.1 Different termination.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12225.1 [Q9NQ55-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7359

NCBI Reference Sequences

More...
RefSeqi
NP_001035754.1, NM_001040664.2
NP_064615.3, NM_020230.6 [Q9NQ55-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000253107; ENSP00000253107; ENSG00000130810 [Q9NQ55-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56342
692312

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:56342
hsa:692312

UCSC genome browser

More...
UCSCi
uc002mmz.3, human [Q9NQ55-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ292529 mRNA Translation: CAB99252.1
AC020931 Genomic DNA No translation available.
BC000535 mRNA Translation: AAH00535.2
BC009833 mRNA Translation: AAH09833.1
BC033202 mRNA Translation: AAH33202.1
BC171852 mRNA No translation available.
AJ300588 mRNA Translation: CAC18877.1 Different termination.
CCDSiCCDS12225.1 [Q9NQ55-1]
PIRiJC7359
RefSeqiNP_001035754.1, NM_001040664.2
NP_064615.3, NM_020230.6 [Q9NQ55-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi121141, 123 interactors
593098, 49 interactors
IntActiQ9NQ55, 124 interactors
MINTiQ9NQ55
STRINGi9606.ENSP00000253107

PTM databases

iPTMnetiQ9NQ55
MetOSiteiQ9NQ55
PhosphoSitePlusiQ9NQ55
SwissPalmiQ9NQ55

Polymorphism and mutation databases

BioMutaiPPAN
DMDMi21264056

2D gel databases

SWISS-2DPAGEiQ9NQ55

Proteomic databases

EPDiQ9NQ55
jPOSTiQ9NQ55
MassIVEiQ9NQ55
MaxQBiQ9NQ55
PaxDbiQ9NQ55
PeptideAtlasiQ9NQ55
PRIDEiQ9NQ55
ProteomicsDBi82082 [Q9NQ55-1]
82083 [Q9NQ55-2]
8341

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
42826, 141 antibodies

The DNASU plasmid repository

More...
DNASUi
56342
692312

Genome annotation databases

EnsembliENST00000253107; ENSP00000253107; ENSG00000130810 [Q9NQ55-1]
GeneIDi56342
692312
KEGGihsa:56342
hsa:692312
UCSCiuc002mmz.3, human [Q9NQ55-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56342
692312
DisGeNETi56342
692312
EuPathDBiHostDB:ENSG00000130810.19

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PPAN
HGNCiHGNC:9227, PPAN
HPAiENSG00000130810, Low tissue specificity
MIMi607793, gene
neXtProtiNX_Q9NQ55
OpenTargetsiENSG00000130810
ENSG00000243207
PharmGKBiPA162399971

GenAtlas: human gene database

More...
GenAtlasi
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Phylogenomic databases

eggNOGiKOG2963, Eukaryota
GeneTreeiENSGT00530000064158
HOGENOMiCLU_026936_0_1_1
InParanoidiQ9NQ55
KOiK14859
OMAiVTHLMLF
OrthoDBi353508at2759
PhylomeDBiQ9NQ55
TreeFamiTF318923

Enzyme and pathway databases

PathwayCommonsiQ9NQ55

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
56342, 709 hits in 863 CRISPR screens
692312, 240 hits in 837 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
PPAN
PharosiQ9NQ55, Tbio

Protein Ontology

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PROi
PR:Q9NQ55
RNActiQ9NQ55, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000130810, Expressed in sural nerve and 197 other tissues
ExpressionAtlasiQ9NQ55, baseline and differential
GenevisibleiQ9NQ55, HS

Family and domain databases

InterProiView protein in InterPro
IPR007109, Brix
PfamiView protein in Pfam
PF04427, Brix, 1 hit
SMARTiView protein in SMART
SM00879, Brix, 1 hit
PROSITEiView protein in PROSITE
PS50833, BRIX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSSF1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NQ55
Secondary accession number(s): C9J3F9, Q9BW97, Q9H170
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: October 1, 2000
Last modified: August 12, 2020
This is version 177 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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