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Protein

Nuclear receptor-interacting protein 3

Gene

NRIP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Protein family/group databases

MEROPSiA28.002

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear receptor-interacting protein 3
Alternative name(s):
Sarcoma antigen NY-SAR-105
Gene namesi
Name:NRIP3
Synonyms:C11orf14
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000175352.10
HGNCiHGNC:1167 NRIP3
MIMi613125 gene
neXtProtiNX_Q9NQ35

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000175352
PharmGKBiPA25481

Polymorphism and mutation databases

BioMutaiNRIP3
DMDMi34395556

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000579531 – 241Nuclear receptor-interacting protein 3Add BLAST241

Proteomic databases

EPDiQ9NQ35
MaxQBiQ9NQ35
PaxDbiQ9NQ35
PeptideAtlasiQ9NQ35
PRIDEiQ9NQ35
ProteomicsDBi82070

PTM databases

GlyConnecti662
iPTMnetiQ9NQ35
PhosphoSitePlusiQ9NQ35
UniCarbKBiQ9NQ35

Expressioni

Gene expression databases

BgeeiENSG00000175352 Expressed in 167 organ(s), highest expression level in Ammon's horn
CleanExiHS_NRIP3
ExpressionAtlasiQ9NQ35 baseline and differential
GenevisibleiQ9NQ35 HS

Organism-specific databases

HPAiHPA040573
HPA058827

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CCDC155Q8N6L05EBI-10311735,EBI-749265

Protein-protein interaction databases

BioGridi121183, 8 interactors
IntActiQ9NQ35, 4 interactors
STRINGi9606.ENSP00000310205

Structurei

3D structure databases

ProteinModelPortaliQ9NQ35
SMRiQ9NQ35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0012 Eukaryota
ENOG410XPA0 LUCA
GeneTreeiENSGT00510000046989
HOGENOMiHOG000236257
HOVERGENiHBG052668
InParanoidiQ9NQ35
OMAiVKSHKHE
OrthoDBiEOG091G0L7S
PhylomeDBiQ9NQ35
TreeFamiTF333421

Family and domain databases

CDDicd05480 NRIP_C, 1 hit
Gene3Di2.40.70.10, 1 hit
InterProiView protein in InterPro
IPR033821 NRIP_C
IPR019103 Peptidase_aspartic_DDI1-type
IPR021109 Peptidase_aspartic_dom_sf
PfamiView protein in Pfam
PF09668 Asp_protease, 1 hit
SUPFAMiSSF50630 SSF50630, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.iShow all

Q9NQ35-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFYSGLLTEG GRKETDMREA ASLRQQRRMK QAVQFIHKDS ADLLPLDGLK
60 70 80 90 100
KLGSSKDMQP HNILQRRLME TNLSKLRSGP RVPWASKTNK LNQAKSEGLK
110 120 130 140 150
KSEEDDMILV SCQCAGKDVK ALVDTGCLYN LISLACVDRL GLKEHVKSHK
160 170 180 190 200
HEGEKLSLPR HLKVVGQIEH LVITLGSLRL DCPAAVVDDN EKNLSLGLQT
210 220 230 240
LRSLKCIINL DKHRLIMGKT DKEEIPFVET VSLNEDNTSE A
Length:241
Mass (Da):26,975
Last modified:October 1, 2000 - v1
Checksum:i3ECFE6A3CE3DB539
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7Z3Y4B7Z3Y4_HUMAN
cDNA FLJ51629, highly similar to Nu...
NRIP3
141Annotation score:
E9PIW3E9PIW3_HUMAN
Nuclear receptor-interacting protei...
NRIP3
160Annotation score:
H0YCM9H0YCM9_HUMAN
Nuclear receptor-interacting protei...
NRIP3
65Annotation score:
H0YEG7H0YEG7_HUMAN
Nuclear receptor-interacting protei...
NRIP3
55Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ400877 Genomic DNA Translation: CAB92286.1
AK024750 mRNA Translation: BAB14984.1
BC008835 mRNA Translation: AAH08835.1
AY211930 mRNA Translation: AAO65183.1
CCDSiCCDS31422.1
RefSeqiNP_065696.1, NM_020645.2
UniGeneiHs.523467

Genome annotation databases

EnsembliENST00000309166; ENSP00000310205; ENSG00000175352
GeneIDi56675
KEGGihsa:56675
UCSCiuc001mhg.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ400877 Genomic DNA Translation: CAB92286.1
AK024750 mRNA Translation: BAB14984.1
BC008835 mRNA Translation: AAH08835.1
AY211930 mRNA Translation: AAO65183.1
CCDSiCCDS31422.1
RefSeqiNP_065696.1, NM_020645.2
UniGeneiHs.523467

3D structure databases

ProteinModelPortaliQ9NQ35
SMRiQ9NQ35
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121183, 8 interactors
IntActiQ9NQ35, 4 interactors
STRINGi9606.ENSP00000310205

Protein family/group databases

MEROPSiA28.002

PTM databases

GlyConnecti662
iPTMnetiQ9NQ35
PhosphoSitePlusiQ9NQ35
UniCarbKBiQ9NQ35

Polymorphism and mutation databases

BioMutaiNRIP3
DMDMi34395556

Proteomic databases

EPDiQ9NQ35
MaxQBiQ9NQ35
PaxDbiQ9NQ35
PeptideAtlasiQ9NQ35
PRIDEiQ9NQ35
ProteomicsDBi82070

Protocols and materials databases

DNASUi56675
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000309166; ENSP00000310205; ENSG00000175352
GeneIDi56675
KEGGihsa:56675
UCSCiuc001mhg.2 human

Organism-specific databases

CTDi56675
EuPathDBiHostDB:ENSG00000175352.10
GeneCardsiNRIP3
HGNCiHGNC:1167 NRIP3
HPAiHPA040573
HPA058827
MIMi613125 gene
neXtProtiNX_Q9NQ35
OpenTargetsiENSG00000175352
PharmGKBiPA25481
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0012 Eukaryota
ENOG410XPA0 LUCA
GeneTreeiENSGT00510000046989
HOGENOMiHOG000236257
HOVERGENiHBG052668
InParanoidiQ9NQ35
OMAiVKSHKHE
OrthoDBiEOG091G0L7S
PhylomeDBiQ9NQ35
TreeFamiTF333421

Miscellaneous databases

ChiTaRSiNRIP3 human
GenomeRNAii56675
PROiPR:Q9NQ35
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000175352 Expressed in 167 organ(s), highest expression level in Ammon's horn
CleanExiHS_NRIP3
ExpressionAtlasiQ9NQ35 baseline and differential
GenevisibleiQ9NQ35 HS

Family and domain databases

CDDicd05480 NRIP_C, 1 hit
Gene3Di2.40.70.10, 1 hit
InterProiView protein in InterPro
IPR033821 NRIP_C
IPR019103 Peptidase_aspartic_DDI1-type
IPR021109 Peptidase_aspartic_dom_sf
PfamiView protein in Pfam
PF09668 Asp_protease, 1 hit
SUPFAMiSSF50630 SSF50630, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiNRIP3_HUMAN
AccessioniPrimary (citable) accession number: Q9NQ35
Secondary accession number(s): Q86WD9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: October 1, 2000
Last modified: September 12, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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