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Entry version 145 (08 May 2019)
Sequence version 1 (01 Oct 2000)
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Protein

Probable palmitoyltransferase ZDHHC4

Gene

ZDHHC4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei179S-palmitoyl cysteine intermediateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.1.225 2681

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable palmitoyltransferase ZDHHC4 (EC:2.3.1.225)
Alternative name(s):
Zinc finger DHHC domain-containing protein 4
Short name:
DHHC-4
Zinc finger protein 374
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZDHHC4
Synonyms:ZNF374
ORF Names:DC1, UNQ5787/PRO19576
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18471 ZDHHC4

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NPG8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei68 – 88HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei193 – 213HelicalSequence analysisAdd BLAST21
Transmembranei256 – 276HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi340R → A: Does not affect localization to the endoplasmic reticulum. 1 Publication1
Mutagenesisi341K → A: Does not affect localization to the endoplasmic reticulum. 1 Publication1
Mutagenesisi342K → A: Impaired localization to the endoplasmic reticulum. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
55146

Open Targets

More...
OpenTargetsi
ENSG00000136247

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38337

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZDHHC4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
28202108

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002128651 – 344Probable palmitoyltransferase ZDHHC4Add BLAST344

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NPG8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NPG8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NPG8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NPG8

PeptideAtlas

More...
PeptideAtlasi
Q9NPG8

PRoteomics IDEntifications database

More...
PRIDEi
Q9NPG8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81994

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NPG8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NPG8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136247 Expressed in 195 organ(s), highest expression level in right testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NPG8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NPG8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA032124
HPA064358

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9NPG8, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9NPG8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000379934

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini149 – 199DHHCPROSITE-ProRule annotationAdd BLAST51

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi341 – 344Di-lysine motif1 Publication4

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The C-terminal di-lysine motif confers endoplasmic reticulum localization.1 Publication
The DHHC domain is required for palmitoyltransferase activity.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1312 Eukaryota
COG5273 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00920000149163

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000253024

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NPG8

KEGG Orthology (KO)

More...
KOi
K20003

Identification of Orthologs from Complete Genome Data

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OMAi
HGLWSNL

Database of Orthologous Groups

More...
OrthoDBi
445686at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NPG8

TreeFam database of animal gene trees

More...
TreeFami
TF330931

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001594 Palmitoyltrfase_DHHC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01529 DHHC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50216 DHHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9NPG8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDFLVLFLFY LASVLMGLVL ICVCSKTHSL KGLARGGAQI FSCIIPECLQ
60 70 80 90 100
RAVHGLLHYL FHTRNHTFIV LHLVLQGMVY TEYTWEVFGY CQELELSLHY
110 120 130 140 150
LLLPYLLLGV NLFFFTLTCG TNPGIITKAN ELLFLHVYEF DEVMFPKNVR
160 170 180 190 200
CSTCDLRKPA RSKHCSVCNW CVHRFDHHCV WVNNCIGAWN IRYFLIYVLT
210 220 230 240 250
LTASAATVAI VSTTFLVHLV VMSDLYQETY IDDLGHLHVM DTVFLIQYLF
260 270 280 290 300
LTFPRIVFML GFVVVLSFLL GGYLLFVLYL AATNQTTNEW YRGDWAWCQR
310 320 330 340
CPLVAWPPSA EPQVHRNIHS HGLRSNLQEI FLPAFPCHER KKQE
Length:344
Mass (Da):39,787
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D2CF22B14036908
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J5I9C9J5I9_HUMAN
Probable palmitoyltransferase ZDHHC...
ZDHHC4
165Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti33L → P in BAD97252 (Ref. 6) Curated1
Sequence conflicti244F → I in CAB66609 (PubMed:11230166).Curated1
Sequence conflicti244F → I in CAG38542 (Ref. 4) Curated1
Sequence conflicti276F → S in CAB66609 (PubMed:11230166).Curated1
Sequence conflicti276F → S in CAG38542 (Ref. 4) Curated1
Sequence conflicti294D → V in CAB66609 (PubMed:11230166).Curated1
Sequence conflicti294D → V in CAG38542 (Ref. 4) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02383253V → M1 PublicationCorresponds to variant dbSNP:rs11559146Ensembl.1
Natural variantiVAR_036260104P → S in a breast cancer sample; somatic mutation. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF201931 mRNA Translation: AAF86867.1
AL136674 mRNA Translation: CAB66609.1
AY359090 mRNA Translation: AAQ89448.1
CR533511 mRNA Translation: CAG38542.1
AK001341 mRNA Translation: BAA91636.1
AK223532 mRNA Translation: BAD97252.1
AC079742 Genomic DNA No translation available.
CH236963 Genomic DNA Translation: EAL23725.1
CH878731 Genomic DNA Translation: EAW55023.1
BC001239 mRNA Translation: AAH01239.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5352.1

NCBI Reference Sequences

More...
RefSeqi
NP_001127859.1, NM_001134387.1
NP_001127860.1, NM_001134388.1
NP_001127861.1, NM_001134389.1
NP_060576.1, NM_018106.3
XP_005249850.1, XM_005249793.2
XP_005249851.1, XM_005249794.3
XP_005249852.1, XM_005249795.2
XP_005249853.1, XM_005249796.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000335965; ENSP00000337475; ENSG00000136247
ENST00000396706; ENSP00000379934; ENSG00000136247
ENST00000396707; ENSP00000379935; ENSG00000136247
ENST00000396709; ENSP00000379937; ENSG00000136247
ENST00000396713; ENSP00000379941; ENSG00000136247
ENST00000405731; ENSP00000385027; ENSG00000136247

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55146

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55146

UCSC genome browser

More...
UCSCi
uc003sqh.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF201931 mRNA Translation: AAF86867.1
AL136674 mRNA Translation: CAB66609.1
AY359090 mRNA Translation: AAQ89448.1
CR533511 mRNA Translation: CAG38542.1
AK001341 mRNA Translation: BAA91636.1
AK223532 mRNA Translation: BAD97252.1
AC079742 Genomic DNA No translation available.
CH236963 Genomic DNA Translation: EAL23725.1
CH878731 Genomic DNA Translation: EAW55023.1
BC001239 mRNA Translation: AAH01239.1
CCDSiCCDS5352.1
RefSeqiNP_001127859.1, NM_001134387.1
NP_001127860.1, NM_001134388.1
NP_001127861.1, NM_001134389.1
NP_060576.1, NM_018106.3
XP_005249850.1, XM_005249793.2
XP_005249851.1, XM_005249794.3
XP_005249852.1, XM_005249795.2
XP_005249853.1, XM_005249796.3

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9NPG8, 2 interactors
MINTiQ9NPG8
STRINGi9606.ENSP00000379934

PTM databases

iPTMnetiQ9NPG8
PhosphoSitePlusiQ9NPG8

Polymorphism and mutation databases

BioMutaiZDHHC4
DMDMi28202108

Proteomic databases

EPDiQ9NPG8
jPOSTiQ9NPG8
MaxQBiQ9NPG8
PaxDbiQ9NPG8
PeptideAtlasiQ9NPG8
PRIDEiQ9NPG8
ProteomicsDBi81994

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55146
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000335965; ENSP00000337475; ENSG00000136247
ENST00000396706; ENSP00000379934; ENSG00000136247
ENST00000396707; ENSP00000379935; ENSG00000136247
ENST00000396709; ENSP00000379937; ENSG00000136247
ENST00000396713; ENSP00000379941; ENSG00000136247
ENST00000405731; ENSP00000385027; ENSG00000136247
GeneIDi55146
KEGGihsa:55146
UCSCiuc003sqh.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55146
DisGeNETi55146

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZDHHC4
HGNCiHGNC:18471 ZDHHC4
HPAiHPA032124
HPA064358
neXtProtiNX_Q9NPG8
OpenTargetsiENSG00000136247
PharmGKBiPA38337

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1312 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00920000149163
HOGENOMiHOG000253024
InParanoidiQ9NPG8
KOiK20003
OMAiHGLWSNL
OrthoDBi445686at2759
PhylomeDBiQ9NPG8
TreeFamiTF330931

Enzyme and pathway databases

BRENDAi2.3.1.225 2681

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZDHHC4 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ZDHHC4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55146

Protein Ontology

More...
PROi
PR:Q9NPG8

Gene expression databases

BgeeiENSG00000136247 Expressed in 195 organ(s), highest expression level in right testis
ExpressionAtlasiQ9NPG8 baseline and differential
GenevisibleiQ9NPG8 HS

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit
PROSITEiView protein in PROSITE
PS50216 DHHC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZDHC4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NPG8
Secondary accession number(s): A4D2N9
, Q53EV7, Q6FIB5, Q9H0R9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: October 1, 2000
Last modified: May 8, 2019
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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