ZDHHC4

Functionⁱ

Palmitoyltransferase that could catalyze the addition of palmitate onto protein substrates including the D₂ dopamine receptor DRD2.1 Publication

Catalytic activityⁱ

hexadecanoyl-CoA
Search proteins in UniProtKB for this molecule.
Search chemical reactions in Rhea for this molecule.
See the description of this molecule in ChEBI.
+
L-cysteinyl-[protein]
Search proteins in UniProtKB for this molecule.
Search chemical reactions in Rhea for this molecule.
=
CoA
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Search chemical reactions in Rhea for this molecule.
See the description of this molecule in ChEBI.
+
S-hexadecanoyl-L-cysteinyl-[protein]
Search proteins in UniProtKB for this molecule.
Search chemical reactions in Rhea for this molecule.
1 Publication
Manual assertion inferred by curator fromⁱ
- Ref.12
  "Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability."
  Ebersole B., Petko J., Woll M., Murakami S., Sokolina K., Wong V., Stagljar I., Luescher B., Levenson R.
  PLoS ONE 10:e0140661-e0140661(2015) [PubMed] [Europe PMC] [Abstract]
  Cited for: FUNCTION, CATALYTIC ACTIVITY, SUBCELLULAR LOCATION.
EC:
2.3.1.225
- Search proteins in UniProtKB for this EC number.
- See the description of this EC number in ENZYME.
1 Publication
Manual assertion inferred by curator fromⁱ
- Ref.12
  "Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability."
  Ebersole B., Petko J., Woll M., Murakami S., Sokolina K., Wong V., Stagljar I., Luescher B., Levenson R.
  PLoS ONE 10:e0140661-e0140661(2015) [PubMed] [Europe PMC] [Abstract]
  Cited for: FUNCTION, CATALYTIC ACTIVITY, SUBCELLULAR LOCATION.
This reaction proceeds in the
forward
Search for this reaction in UniProtKB.
See the description of this reaction in Rhea.
1 Publication
Manual assertion inferred by curator fromⁱ
- Ref.12
  "Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability."
  Ebersole B., Petko J., Woll M., Murakami S., Sokolina K., Wong V., Stagljar I., Luescher B., Levenson R.
  PLoS ONE 10:e0140661-e0140661(2015) [PubMed] [Europe PMC] [Abstract]
  Cited for: FUNCTION, CATALYTIC ACTIVITY, SUBCELLULAR LOCATION.
direction.
Source:
Rhea
Search for this reaction in UniProtKB.
See the description of this reaction in Rhea.
. Show »« Hide
hexadecanoyl-CoA
zoom
+
L-cysteinyl-[protein]
L-cysteine residue
zoom
=
CoA
+
S-hexadecanoyl-L-cysteinyl-[protein]
S-palmitoyl-L-cysteine residue
zoom

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	179	S-palmitoyl cysteine intermediatePROSITE-ProRule annotation		1

GO - Molecular functionⁱ

protein-cysteine S-palmitoyltransferase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
  Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
  Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

Complete GO annotation on QuickGO ...

GO - Biological processⁱ

Complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Acyltransferase, Transferase

Molecular function

Acyltransferase, Transferase

Enzyme and pathway databases

BRENDAⁱ	2.3.1.225, 2681
PathwayCommonsⁱ	Q9NPG8

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Palmitoyltransferase ZDHHC4Curated (EC:2.3.1.2251 Publication) Alternative name(s): Zinc finger DHHC domain-containing protein 4Imported Short name: DHHC-4 Zinc finger protein 374
Gene namesⁱ	Name:ZDHHC4Imported Synonyms:ZNF374 ORF Names:DC1, UNQ5787/PRO19576
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:18471, ZDHHC4
neXtProtⁱ	NX_Q9NPG8
VEuPathDBⁱ	HostDB:ENSG00000136247.14

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 2	Lumenal1 Publication	2
Transmembraneⁱ	3 – 23	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	24 – 67	Cytoplasmic1 PublicationAdd BLAST	44
Transmembraneⁱ	68 – 88	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	89 – 99	Lumenal1 PublicationAdd BLAST	11
Transmembraneⁱ	100 – 120	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	121 – 192	Cytoplasmic1 PublicationAdd BLAST	72
Transmembraneⁱ	193 – 213	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	214 – 255	Lumenal1 PublicationAdd BLAST	42
Transmembraneⁱ	256 – 276	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	277 – 344	Cytoplasmic1 PublicationAdd BLAST	68

Keywords - Cellular componentⁱ

Cell membrane, Endoplasmic reticulum, Golgi apparatus, Membrane

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	340	R → A: Does not affect localization to the endoplasmic reticulum. 1 Publication	1
Mutagenesisⁱ	341	K → A: Does not affect localization to the endoplasmic reticulum. 1 Publication	1
Mutagenesisⁱ	342	K → A: Impaired localization to the endoplasmic reticulum. 1 Publication	1

Organism-specific databases

DisGeNET More...DisGeNETⁱ	55146
Open Targets More...OpenTargetsⁱ	ENSG00000136247
PharmGKBⁱ	PA38337

Miscellaneous databases

Pharosⁱ	Q9NPG8, Tdark

Pharosⁱ

Q9NPG8, Tdark

Genetic variation databases

BioMutaⁱ	ZDHHC4
DMDMⁱ	28202108

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000212865	1 – 344	Palmitoyltransferase ZDHHC4Add BLAST		344

Keywords - PTMⁱ

Lipoprotein, Palmitate

Proteomic databases

EPDⁱ	Q9NPG8
jPOSTⁱ	Q9NPG8
MassIVEⁱ	Q9NPG8
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9NPG8
PaxDbⁱ	Q9NPG8
PeptideAtlas More...PeptideAtlasⁱ	Q9NPG8
PRIDEⁱ	Q9NPG8
ProteomicsDBⁱ	81994

PTM databases

iPTMnetⁱ	Q9NPG8
PhosphoSitePlusⁱ	Q9NPG8
SwissPalmⁱ	Q9NPG8

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000136247, Expressed in pancreas and 209 other tissues
ExpressionAtlasⁱ	Q9NPG8, baseline and differential
Genevisibleⁱ	Q9NPG8, HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	ENSG00000136247, Low tissue specificity

HPAⁱ

ENSG00000136247, Low tissue specificity

Interactionⁱ

Binary interactionsⁱ

Hide details

Q9NPG8

With	#Exp.	IntAct
CLDND1 [Q9NY35]	3	EBI-20009624,EBI-4319704
TUSC5 [A5PKU2]	3	EBI-20009624,EBI-11988865

Protein-protein interaction databases

BioGRIDⁱ	120449, 3 interactors
IntActⁱ	Q9NPG8, 3 interactors
Molecular INTeraction database More...MINTⁱ	Q9NPG8
STRINGⁱ	9606.ENSP00000379934

Miscellaneous databases

RNActⁱ	Q9NPG8, protein

RNActⁱ

Q9NPG8, protein

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	149 – 199	DHHCPROSITE-ProRule annotationAdd BLAST		51

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	341 – 344	Di-lysine motif1 Publication		4

Domainⁱ

The C-terminal di-lysine motif confers endoplasmic reticulum localization.1 Publication

The DHHC domain is required for palmitoyltransferase activity.By similarity

Sequence similaritiesⁱ

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG1312, Eukaryota
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149163
HOGENOMⁱ	CLU_042181_4_0_1
InParanoidⁱ	Q9NPG8
OMAⁱ	CKYSGQQ
Database of Orthologous Groups More...OrthoDBⁱ	445686at2759
PhylomeDBⁱ	Q9NPG8
TreeFamⁱ	TF330931

Family and domain databases

InterProⁱ	View protein in InterPro IPR001594, Palmitoyltrfase_DHHC
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01529, DHHC, 1 hit
PROSITEⁱ	View protein in PROSITE PS50216, DHHC, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q9NPG8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDFLVLFLFY LASVLMGLVL ICVCSKTHSL KGLARGGAQI FSCIIPECLQ 
        60         70         80         90        100
RAVHGLLHYL FHTRNHTFIV LHLVLQGMVY TEYTWEVFGY CQELELSLHY 
       110        120        130        140        150
LLLPYLLLGV NLFFFTLTCG TNPGIITKAN ELLFLHVYEF DEVMFPKNVR 
       160        170        180        190        200
CSTCDLRKPA RSKHCSVCNW CVHRFDHHCV WVNNCIGAWN IRYFLIYVLT 
       210        220        230        240        250
LTASAATVAI VSTTFLVHLV VMSDLYQETY IDDLGHLHVM DTVFLIQYLF 
       260        270        280        290        300
LTFPRIVFML GFVVVLSFLL GGYLLFVLYL AATNQTTNEW YRGDWAWCQR 
       310        320        330        340 
CPLVAWPPSA EPQVHRNIHS HGLRSNLQEI FLPAFPCHER KKQE

Length:344

Mass (Da):39,787

Last modified:October 1, 2000 - v1

Checksum:ⁱ3D2CF22B14036908

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	C9J5I9	C9J5I9_HUMAN		Palmitoyltransferase ZDHHC4 Palmitoyltransferase ZDHHC4	ZDHHC4	165	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	33	L → P in BAD97252 (Ref. 6) Curated	1
Sequence conflictⁱ	244	F → I in CAB66609 (PubMed:11230166).Curated	1
Sequence conflictⁱ	244	F → I in CAG38542 (Ref. 4) Curated	1
Sequence conflictⁱ	276	F → S in CAB66609 (PubMed:11230166).Curated	1
Sequence conflictⁱ	276	F → S in CAG38542 (Ref. 4) Curated	1
Sequence conflictⁱ	294	D → V in CAB66609 (PubMed:11230166).Curated	1
Sequence conflictⁱ	294	D → V in CAG38542 (Ref. 4) Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_023832	53	V → M1 PublicationCorresponds to variant dbSNP:rs11559146Ensembl.		1
Natural variantⁱVAR_036260	104	P → S in a breast cancer sample; somatic mutation. 1 Publication		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF201931 mRNA Translation: AAF86867.1 AL136674 mRNA Translation: CAB66609.1 AY359090 mRNA Translation: AAQ89448.1 CR533511 mRNA Translation: CAG38542.1 AK001341 mRNA Translation: BAA91636.1 AK223532 mRNA Translation: BAD97252.1 AC079742 Genomic DNA No translation available. CH236963 Genomic DNA Translation: EAL23725.1 CH878731 Genomic DNA Translation: EAW55023.1 BC001239 mRNA Translation: AAH01239.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5352.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001127859.1, NM_001134387.1 NP_001127860.1, NM_001134388.1 NP_001127861.1, NM_001134389.1 NP_060576.1, NM_018106.3 XP_005249850.1, XM_005249793.2 XP_005249851.1, XM_005249794.3 XP_005249852.1, XM_005249795.2 XP_005249853.1, XM_005249796.3

Genome annotation databases

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9NPG8	Palmitoyltransferase		HUMAN		344	UniRef100_Q9NPG8

Protein	Similar proteins		Species	Score	Length	Source
Q9NPG8	Palmitoyltransferase		HUMAN		344	UniRef90_Q9NPG8
Palmitoyltransferase		PANTR		346
Palmitoyltransferase		PANPA		346
Palmitoyltransferase		RHIRO		344
Palmitoyltransferase		PANPA		344
+15

Protein	Similar proteins		Species	Score	Length	Source
Q9NPG8	Palmitoyltransferase ZDHHC4		BOVIN		343	UniRef50_Q9NPG8
Palmitoyltransferase ZDHHC4		MOUSE		343
Palmitoyltransferase		HUMAN		344
Palmitoyltransferase		PANTR		346
Palmitoyltransferase		PANPA		346
+178

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF201931 mRNA Translation: AAF86867.1 AL136674 mRNA Translation: CAB66609.1 AY359090 mRNA Translation: AAQ89448.1 CR533511 mRNA Translation: CAG38542.1 AK001341 mRNA Translation: BAA91636.1 AK223532 mRNA Translation: BAD97252.1 AC079742 Genomic DNA No translation available. CH236963 Genomic DNA Translation: EAL23725.1 CH878731 Genomic DNA Translation: EAW55023.1 BC001239 mRNA Translation: AAH01239.1
CCDSⁱ	CCDS5352.1
RefSeqⁱ	NP_001127859.1, NM_001134387.1 NP_001127860.1, NM_001134388.1 NP_001127861.1, NM_001134389.1 NP_060576.1, NM_018106.3 XP_005249850.1, XM_005249793.2 XP_005249851.1, XM_005249794.3 XP_005249852.1, XM_005249795.2 XP_005249853.1, XM_005249796.3

3D structure databases

ModBaseⁱ	Search...
SWISS-MODEL-Workspaceⁱ	Submit a new modelling project...

Protein-protein interaction databases

BioGRIDⁱ	120449, 3 interactors
IntActⁱ	Q9NPG8, 3 interactors
MINTⁱ	Q9NPG8
STRINGⁱ	9606.ENSP00000379934

PTM databases

iPTMnetⁱ	Q9NPG8
PhosphoSitePlusⁱ	Q9NPG8
SwissPalmⁱ	Q9NPG8

Genetic variation databases

BioMutaⁱ	ZDHHC4
DMDMⁱ	28202108

Proteomic databases

EPDⁱ	Q9NPG8
jPOSTⁱ	Q9NPG8
MassIVEⁱ	Q9NPG8
MaxQBⁱ	Q9NPG8
PaxDbⁱ	Q9NPG8
PeptideAtlasⁱ	Q9NPG8
PRIDEⁱ	Q9NPG8
ProteomicsDBⁱ	81994

Protocols and materials databases

Antibodypediaⁱ	24908, 46 antibodies
The DNASU plasmid repository More...DNASUⁱ	55146

Genome annotation databases

Ensemblⁱ	ENST00000335965; ENSP00000337475; ENSG00000136247 ENST00000396706; ENSP00000379934; ENSG00000136247 ENST00000396707; ENSP00000379935; ENSG00000136247 ENST00000396709; ENSP00000379937; ENSG00000136247 ENST00000396713; ENSP00000379941; ENSG00000136247 ENST00000405731; ENSP00000385027; ENSG00000136247
GeneIDⁱ	55146
KEGGⁱ	hsa:55146
UCSCⁱ	uc003sqh.4, human

Organism-specific databases

CTDⁱ	55146
DisGeNETⁱ	55146
GeneCardsⁱ	ZDHHC4
HGNCⁱ	HGNC:18471, ZDHHC4
HPAⁱ	ENSG00000136247, Low tissue specificity
neXtProtⁱ	NX_Q9NPG8
OpenTargetsⁱ	ENSG00000136247
PharmGKBⁱ	PA38337
VEuPathDBⁱ	HostDB:ENSG00000136247.14
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1312, Eukaryota
GeneTreeⁱ	ENSGT00920000149163
HOGENOMⁱ	CLU_042181_4_0_1
InParanoidⁱ	Q9NPG8
OMAⁱ	CKYSGQQ
OrthoDBⁱ	445686at2759
PhylomeDBⁱ	Q9NPG8
TreeFamⁱ	TF330931

Enzyme and pathway databases

BRENDAⁱ	2.3.1.225, 2681
PathwayCommonsⁱ	Q9NPG8

Miscellaneous databases

BioGRID-ORCSⁱ	55146, 1 hit in 878 CRISPR screens
ChiTaRSⁱ	ZDHHC4, human
GeneWikiⁱ	ZDHHC4
GenomeRNAiⁱ	55146
Pharosⁱ	Q9NPG8, Tdark
Protein Ontology More...PROⁱ	PR:Q9NPG8
RNActⁱ	Q9NPG8, protein

Gene expression databases

Bgeeⁱ	ENSG00000136247, Expressed in pancreas and 209 other tissues
ExpressionAtlasⁱ	Q9NPG8, baseline and differential
Genevisibleⁱ	Q9NPG8, HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR001594, Palmitoyltrfase_DHHC
Pfamⁱ	View protein in Pfam PF01529, DHHC, 1 hit
PROSITEⁱ	View protein in PROSITE PS50216, DHHC, 1 hit
ProtoNetⁱ	Search...
MobiDBⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZDHC4_HUMAN
Accessionⁱ	Q9NPG8Primary (citable) accession number: Q9NPG8 Secondary accession number(s): A4D2N9 , Q53EV7, Q6FIB5, Q9H0R9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 2003
	Last sequence update:	October 1, 2000
	Last modified:	February 10, 2021
	This is version 155 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Reference proteome

Documents

Human entries with genetic variants
List of human entries with genetic variants
Human variants curated from literature reports
Index of human variants curated from literature reports
SIMILARITY comments
Index of protein domains and families
Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9NPG8 (ZDHC4_HUMAN)

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Palmitoyltransferase ZDHHC4

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Golgi apparatus

Endoplasmic reticulum

Endoplasmic reticulum

Golgi apparatus

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Miscellaneous databases

Genetic variation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Q9NPG8

Protein-protein interaction databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Motif

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Genetic variation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

Catalytic activityⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ