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UniProtKB - Q9NPC7 (MYNN_HUMAN)

Entry version 160 (13 Feb 2019)
Sequence version 1 (01 Oct 2000)
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Protein

Myoneurin

Gene

MYNN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri302 – 324C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 381C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri387 – 409C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri415 – 437C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri443 – 465C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri471 – 493C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri499 – 522C2H2-type 8PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myoneurin
Alternative name(s):
Zinc finger and BTB domain-containing protein 31
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYNN
Synonyms:OSZF, ZBTB31
ORF Names:SBBIZ1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000085274.15

Human Gene Nomenclature Database

More...HGNCi		HGNC:14955 MYNN

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		606042 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9NPC7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		55892

Open Targets

More...OpenTargetsi		ENSG00000085274

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA31393

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MYNN

Domain mapping of disease mutations (DMDM)

More...DMDMi		74761639

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002482171 – 610MyoneurinAdd BLAST610

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei289PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9NPC7

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9NPC7

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9NPC7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9NPC7

PeptideAtlas

More...PeptideAtlasi		Q9NPC7

PRoteomics IDEntifications database

More...PRIDEi		Q9NPC7

ProteomicsDB human proteome resource

More...ProteomicsDBi		81968
81969 [Q9NPC7-2]
81970 [Q9NPC7-3]
81971 [Q9NPC7-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9NPC7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9NPC7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mainly expressed in the neuromuscular system. Located in and around synaptic myonuclei in adult muscle. Expression is dysregulated after nerve injury. Also found in the testis, ovary and placenta.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000085274 Expressed in 213 organ(s), highest expression level in buccal mucosa cell

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9NPC7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9NPC7 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA045149

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		120982, 6 interactors

Protein interaction database and analysis system

More...IntActi		Q9NPC7, 5 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000326240

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1610
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2VPKX-ray2.00A4-117[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		Q9NPC7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9NPC7

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9NPC7

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 89BTBPROSITE-ProRule annotationAdd BLAST66

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi174 – 190Nuclear localization signalSequence analysisAdd BLAST17
Motifi257 – 262Nuclear localization signalSequence analysis6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi180 – 184Poly-Lys5

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri302 – 324C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 381C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri387 – 409C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri415 – 437C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri443 – 465C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri471 – 493C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri499 – 522C2H2-type 8PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161266

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG055746

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9NPC7

Identification of Orthologs from Complete Genome Data

More...OMAi		SSIEDHP

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9NPC7

TreeFam database of animal gene trees

More...TreeFami		TF330787

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 8 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 8 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NPC7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQYSHHCEHL LERLNKQREA GFLCDCTIVI GEFQFKAHRN VLASFSEYFG 
        60         70         80         90        100
AIYRSTSENN VFLDQSQVKA DGFQKLLEFI YTGTLNLDSW NVKEIHQAAD 
       110        120        130        140        150
YLKVEEVVTK CKIKMEDFAF IANPSSTEIS SITGNIELNQ QTCLLTLRDY 
       160        170        180        190        200
NNREKSEVST DLIQANPKQG ALAKKSSQTK KKKKAFNSPK TGQNKTVQYP 
       210        220        230        240        250
SDILENASVE LFLDANKLPT PVVEQVAQIN DNSELELTSV VENTFPAQDI 
       260        270        280        290        300
VHTVTVKRKR GKSQPNCALK EHSMSNIASV KSPYEAENSG EELDQRYSKA 
       310        320        330        340        350
KPMCNTCGKV FSEASSLRRH MRIHKGVKPY VCHLCGKAFT QCNQLKTHVR 
       360        370        380        390        400
THTGEKPYKC ELCDKGFAQK CQLVFHSRMH HGEEKPYKCD VCNLQFATSS 
       410        420        430        440        450
NLKIHARKHS GEKPYVCDRC GQRFAQASTL TYHVRRHTGE KPYVCDTCGK 
       460        470        480        490        500
AFAVSSSLIT HSRKHTGEKP YICGICGKSF ISSGELNKHF RSHTGERPFI 
       510        520        530        540        550
CELCGNSYTD IKNLKKHKTK VHSGADKTLD SSAEDHTLSE QDSIQKSPLS 
       560        570        580        590        600
ETMDVKPSDM TLPLALPLGT EDHHMLLPVT DTQSPTSDTL LRSTVNGYSE 
       610
PQLIFLQQLY
Length:610
Mass (Da):68,682
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i842B62DDC2C81480
GO
Isoform 2 (identifier: Q9NPC7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     496-524: Missing.

Show »
Length:581
Mass (Da):65,353
Checksum:iFDACC972CDB5B91E
GO
Isoform 3 (identifier: Q9NPC7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     495-500: GERPFI → VVWSMN
     501-610: Missing.

Show »
Length:500
Mass (Da):56,545
Checksum:iCE38A314B03008E5
GO
Isoform 4 (identifier: Q9NPC7-4) [UniParc]FASTAAdd to basket
Also known as: m4b

The sequence of this isoform differs from the canonical sequence as follows:
     89-91: SWN → RDI
     92-610: Missing.

Show »
Length:91
Mass (Da):10,611
Checksum:iA3032286424DA0FC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
R4GMT1R4GMT1_HUMAN
Myoneurin
MYNN
238Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti198Q → R in BAC55898 (Ref. 2) Curated1
Sequence conflicti198Q → R in BAC55899 (Ref. 2) Curated1
Sequence conflicti292E → D in CAB61393 (PubMed:17974005).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02021389 – 91SWN → RDI in isoform 4. 2 Publications3
Alternative sequenceiVSP_02021492 – 610Missing in isoform 4. 2 PublicationsAdd BLAST519
Alternative sequenceiVSP_020215495 – 500GERPFI → VVWSMN in isoform 3. 1 Publication6
Alternative sequenceiVSP_020216496 – 524Missing in isoform 2. 1 PublicationAdd BLAST29
Alternative sequenceiVSP_020217501 – 610Missing in isoform 3. 1 PublicationAdd BLAST110

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF148848 mRNA Translation: AAF73138.1
AY286322, AY286321 Genomic DNA Translation: AAP44763.1
AY286328
, AY286323, AY286325, AY286324, AY286326, AY286327 Genomic DNA Translation: AAP44764.1
AY514901 mRNA Translation: AAR99055.1
AY515294 Genomic DNA Translation: AAR99843.1
AY515691 mRNA Translation: AAS38566.1
AY515692 mRNA Translation: AAS38567.1
AY541760 mRNA Translation: AAS87376.1
AY541761 mRNA Translation: AAS87377.1
AB079777 mRNA Translation: BAC55898.1
AB079778 mRNA Translation: BAC55899.1
AB079779 Genomic DNA Translation: BAC55900.1
AF076249 mRNA Translation: AAF80160.1
AF155508 mRNA Translation: AAF74822.1
AK021646 mRNA Translation: BAB13862.1
AK092022 mRNA Translation: BAG52468.1
AK312527 mRNA Translation: BAG35426.1
AL133070 mRNA Translation: CAB61393.1
BX648128 mRNA Translation: CAI46035.1
CH471052 Genomic DNA Translation: EAW78544.1
CH471052 Genomic DNA Translation: EAW78546.1
BC033620 mRNA Translation: AAH33620.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS3207.1 [Q9NPC7-1]
CCDS54671.1 [Q9NPC7-2]

Protein sequence database of the Protein Information Resource

More...PIRi		JC7315
T42670

NCBI Reference Sequences

More...RefSeqi		NP_001172047.1, NM_001185118.1 [Q9NPC7-1]
NP_001172048.1, NM_001185119.1 [Q9NPC7-2]
NP_061127.1, NM_018657.4 [Q9NPC7-1]
XP_011511289.1, XM_011512987.1
XP_016862353.1, XM_017006864.1 [Q9NPC7-1]

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.507025
Hs.630744

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000349841; ENSP00000326240; ENSG00000085274 [Q9NPC7-1]
ENST00000356716; ENSP00000349150; ENSG00000085274 [Q9NPC7-1]
ENST00000544106; ENSP00000440637; ENSG00000085274 [Q9NPC7-2]
ENST00000602751; ENSP00000473654; ENSG00000085274 [Q9NPC7-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55892

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55892

UCSC genome browser

More...UCSCi		uc003fft.4 human [Q9NPC7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF148848 mRNA Translation: AAF73138.1
AY286322, AY286321 Genomic DNA Translation: AAP44763.1
AY286328
, AY286323, AY286325, AY286324, AY286326, AY286327 Genomic DNA Translation: AAP44764.1
AY514901 mRNA Translation: AAR99055.1
AY515294 Genomic DNA Translation: AAR99843.1
AY515691 mRNA Translation: AAS38566.1
AY515692 mRNA Translation: AAS38567.1
AY541760 mRNA Translation: AAS87376.1
AY541761 mRNA Translation: AAS87377.1
AB079777 mRNA Translation: BAC55898.1
AB079778 mRNA Translation: BAC55899.1
AB079779 Genomic DNA Translation: BAC55900.1
AF076249 mRNA Translation: AAF80160.1
AF155508 mRNA Translation: AAF74822.1
AK021646 mRNA Translation: BAB13862.1
AK092022 mRNA Translation: BAG52468.1
AK312527 mRNA Translation: BAG35426.1
AL133070 mRNA Translation: CAB61393.1
BX648128 mRNA Translation: CAI46035.1
CH471052 Genomic DNA Translation: EAW78544.1
CH471052 Genomic DNA Translation: EAW78546.1
BC033620 mRNA Translation: AAH33620.1
CCDSiCCDS3207.1 [Q9NPC7-1]
CCDS54671.1 [Q9NPC7-2]
PIRiJC7315
T42670
RefSeqiNP_001172047.1, NM_001185118.1 [Q9NPC7-1]
NP_001172048.1, NM_001185119.1 [Q9NPC7-2]
NP_061127.1, NM_018657.4 [Q9NPC7-1]
XP_011511289.1, XM_011512987.1
XP_016862353.1, XM_017006864.1 [Q9NPC7-1]
UniGeneiHs.507025
Hs.630744

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2VPKX-ray2.00A4-117[»]
ProteinModelPortaliQ9NPC7
SMRiQ9NPC7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120982, 6 interactors
IntActiQ9NPC7, 5 interactors
STRINGi9606.ENSP00000326240

PTM databases

iPTMnetiQ9NPC7
PhosphoSitePlusiQ9NPC7

Polymorphism and mutation databases

BioMutaiMYNN
DMDMi74761639

Proteomic databases

EPDiQ9NPC7
jPOSTiQ9NPC7
MaxQBiQ9NPC7
PaxDbiQ9NPC7
PeptideAtlasiQ9NPC7
PRIDEiQ9NPC7
ProteomicsDBi81968
81969 [Q9NPC7-2]
81970 [Q9NPC7-3]
81971 [Q9NPC7-4]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		55892
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000349841; ENSP00000326240; ENSG00000085274 [Q9NPC7-1]
ENST00000356716; ENSP00000349150; ENSG00000085274 [Q9NPC7-1]
ENST00000544106; ENSP00000440637; ENSG00000085274 [Q9NPC7-2]
ENST00000602751; ENSP00000473654; ENSG00000085274 [Q9NPC7-4]
GeneIDi55892
KEGGihsa:55892
UCSCiuc003fft.4 human [Q9NPC7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55892
DisGeNETi55892
EuPathDBiHostDB:ENSG00000085274.15

GeneCards: human genes, protein and diseases

More...GeneCardsi		MYNN
HGNCiHGNC:14955 MYNN
HPAiHPA045149
MIMi606042 gene
neXtProtiNX_Q9NPC7
OpenTargetsiENSG00000085274
PharmGKBiPA31393

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000161266
HOVERGENiHBG055746
InParanoidiQ9NPC7
OMAiSSIEDHP
OrthoDBi1318335at2759
PhylomeDBiQ9NPC7
TreeFamiTF330787

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MYNN human
EvolutionaryTraceiQ9NPC7

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55892

Protein Ontology

More...PROi		PR:Q9NPC7

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000085274 Expressed in 213 organ(s), highest expression level in buccal mucosa cell
ExpressionAtlasiQ9NPC7 baseline and differential
GenevisibleiQ9NPC7 HS

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 8 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 8 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYNN_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NPC7
Secondary accession number(s): B2R6C9
, Q6QHA6, Q6QHA7, Q6R3G1, Q6R3G2, Q6R4A0, Q7Z716, Q7Z717, Q86Z11, Q86Z12, Q9NS01, Q9UIW8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: October 1, 2000
Last modified: February 13, 2019
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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