LTB4R2

Functionⁱ

Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Caution

It is uncertain whether Met-1 or Met-32 is the initiator.Curated

GO - Molecular functionⁱ

G-protein coupled peptide receptor activity Source: GO_Central
leukotriene B4 receptor activity Source: Ensembl
leukotriene receptor activity
Source: ProtInc
Traceable author statementⁱ
- 10889186

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

chemotaxis
Source: ProtInc
Traceable author statementⁱ
- 10889186
G-protein coupled receptor signaling pathway Source: Reactome
keratinocyte migration Source: Ensembl
negative regulation of adenylate cyclase activity
Source: ProtInc
Traceable author statementⁱ
- 10889186
neuropeptide signaling pathway Source: GO_Central
phospholipase C-activating G-protein coupled receptor signaling pathway Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-391906 Leukotriene receptors R-HSA-416476 G alpha (q) signalling events
SIGNORⁱ	Q9NPC1

Chemistry databases

SwissLipidsⁱ	SLP:000001556

SwissLipidsⁱ

SLP:000001556

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Leukotriene B4 receptor 2 Short name: LTB4-R 2 Short name: LTB4-R2 Alternative name(s): LTB4 receptor JULF2 Leukotriene B4 receptor BLT2 Seven transmembrane receptor BLTR2
Gene namesⁱ	Name:LTB4R2 Synonyms:BLT2R, BLTR2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000213906.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:19260 LTB4R2
MIMⁱ	605773 gene
neXtProtⁱ	NX_Q9NPC1

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 55	ExtracellularSequence analysisAdd BLAST	55
Transmembraneⁱ	56 – 76	Helical; Name=1Sequence analysisAdd BLAST	21
Topological domainⁱ	77 – 91	CytoplasmicSequence analysisAdd BLAST	15
Transmembraneⁱ	92 – 112	Helical; Name=2Sequence analysisAdd BLAST	21
Topological domainⁱ	113 – 127	ExtracellularSequence analysisAdd BLAST	15
Transmembraneⁱ	128 – 148	Helical; Name=3Sequence analysisAdd BLAST	21
Topological domainⁱ	149 – 172	CytoplasmicSequence analysisAdd BLAST	24
Transmembraneⁱ	173 – 193	Helical; Name=4Sequence analysisAdd BLAST	21
Topological domainⁱ	194 – 216	ExtracellularSequence analysisAdd BLAST	23
Transmembraneⁱ	217 – 237	Helical; Name=5Sequence analysisAdd BLAST	21
Topological domainⁱ	238 – 256	CytoplasmicSequence analysisAdd BLAST	19
Transmembraneⁱ	257 – 277	Helical; Name=6Sequence analysisAdd BLAST	21
Topological domainⁱ	278 – 306	ExtracellularSequence analysisAdd BLAST	29
Transmembraneⁱ	307 – 327	Helical; Name=7Sequence analysisAdd BLAST	21
Topological domainⁱ	328 – 389	CytoplasmicSequence analysisAdd BLAST	62

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	56413
Open Targets More...OpenTargetsⁱ	ENSG00000213906
PharmGKBⁱ	PA134910672

Chemistry databases

ChEMBLⁱ	CHEMBL3191
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	268

Polymorphism and mutation databases

BioMutaⁱ	LTB4R2
DMDMⁱ	23821812

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000069711	1 – 389	Leukotriene B4 receptor 2Add BLAST		389

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Glycosylationⁱ	41	N-linked (GlcNAc...) asparagineSequence analysis		1

Keywords - PTMⁱ

Glycoprotein

Proteomic databases

EPDⁱ	Q9NPC1
PaxDbⁱ	Q9NPC1
PRIDEⁱ	Q9NPC1
ProteomicsDBⁱ	81963

PTM databases

iPTMnetⁱ	Q9NPC1
PhosphoSitePlusⁱ	Q9NPC1

Expressionⁱ

Tissue specificityⁱ

Widely expressed.

Gene expression databases

Bgeeⁱ	ENSG00000213906 Expressed in 86 organ(s), highest expression level in ectocervix
CleanExⁱ	HS_LTB4R2
ExpressionAtlasⁱ	Q9NPC1 baseline and differential
Genevisibleⁱ	Q9NPC1 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB022689 HPA029680 HPA072921

HPAⁱ

CAB022689
HPA029680
HPA072921

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	121143, 4 interactors
IntActⁱ	Q9NPC1, 1 interactor
Molecular INTeraction database More...MINTⁱ	Q9NPC1
STRINGⁱ	9606.ENSP00000433290

Chemistry databases

BindingDBⁱ

Q9NPC1

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9NPC1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149097
HOGENOMⁱ	HOG000008594
HOVERGENⁱ	HBG104134
InParanoidⁱ	Q9NPC1
KEGG Orthology (KO) More...KOⁱ	K04297
OMAⁱ	SREGTME
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0G5V
PhylomeDBⁱ	Q9NPC1
TreeFamⁱ	TF330976

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR003981 Leukotriene_B4_rcpt IPR003982 Leukotriene_B4_typ-2_rcpt
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01478 LTB2RECEPTOR PR01476 LTBRECEPTOR
PROSITEⁱ	View protein in PROSITE PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9NPC1-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAPSHRASQV GFCPTPERPL WRLPPTCRPR RMSVCYRPPG NETLLSWKTS 
        60         70         80         90        100
RATGTAFLLL AALLGLPGNG FVVWSLAGWR PARGRPLAAT LVLHLALADG 
       110        120        130        140        150
AVLLLTPLFV AFLTRQAWPL GQAGCKAVYY VCALSMYASV LLTGLLSLQR 
       160        170        180        190        200
CLAVTRPFLA PRLRSPALAR RLLLAVWLAA LLLAVPAAVY RHLWRDRVCQ 
       210        220        230        240        250
LCHPSPVHAA AHLSLETLTA FVLPFGLMLG CYSVTLARLR GARWGSGRHG 
       260        270        280        290        300
ARVGRLVSAI VLAFGLLWAP YHAVNLLQAV AALAPPEGAL AKLGGAGQAA 
       310        320        330        340        350
RAGTTALAFF SSSVNPVLYV FTAGDLLPRA GPRFLTRLFE GSGEARGGGR 
       360        370        380 
SREGTMELRT TPQLKVVGQG RGNGDPGGGM EKDGPEWDL

Length:389

Mass (Da):41,525

Last modified:October 1, 2000 - v1

Checksum:ⁱ8D6BC5A73A42F544

GO

Isoform 2 (identifier: Q9NPC1-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-31: Missing.

« Hide

        10         20         30         40         50
MSVCYRPPGN ETLLSWKTSR ATGTAFLLLA ALLGLPGNGF VVWSLAGWRP 
        60         70         80         90        100
ARGRPLAATL VLHLALADGA VLLLTPLFVA FLTRQAWPLG QAGCKAVYYV 
       110        120        130        140        150
CALSMYASVL LTGLLSLQRC LAVTRPFLAP RLRSPALARR LLLAVWLAAL 
       160        170        180        190        200
LLAVPAAVYR HLWRDRVCQL CHPSPVHAAA HLSLETLTAF VLPFGLMLGC 
       210        220        230        240        250
YSVTLARLRG ARWGSGRHGA RVGRLVSAIV LAFGLLWAPY HAVNLLQAVA 
       260        270        280        290        300
ALAPPEGALA KLGGAGQAAR AGTTALAFFS SSVNPVLYVF TAGDLLPRAG 
       310        320        330        340        350
PRFLTRLFEG SGEARGGGRS REGTMELRTT PQLKVVGQGR GNGDPGGGME 

KDGPEWDL

Note: No experimental confirmation available.

Show »

Length:358

Mass (Da):37,942

Checksum:ⁱ5F5D98179CE00F3D

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E9PNJ6	E9PNJ6_HUMAN	Leukotriene B4 receptor 2 Leukotriene B4 receptor 2	LTB4R2	319	Annotation score:
E9PIC1	E9PIC1_HUMAN	Leukotriene B4 receptor 2 Leukotriene B4 receptor 2	LTB4R2	160	Annotation score:

Sequence cautionⁱ

The sequence BAB00610 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_044885	1 – 31	Missing in isoform 2. 1 PublicationAdd BLAST		31

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF277230 mRNA Translation: AAF81261.1 AB029892 mRNA Translation: BAA99553.1 AB008193 Genomic DNA Translation: BAB00610.1 Different initiation. AB032558 mRNA Translation: BAD83590.1 AJ278605 Genomic DNA Translation: CAB96134.1 AY268433 Genomic DNA Translation: AAP23200.1 AL096870 Genomic DNA No translation available. CH471078 Genomic DNA Translation: EAW66030.1 AF308571 mRNA Translation: AAG40857.1 AB044402 mRNA Translation: BAA99539.1 AB083604 Genomic DNA Translation: BAB89317.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS9625.2 [Q9NPC1-2]
PIRⁱ	JC7356
NCBI Reference Sequences More...RefSeqⁱ	NP_001158164.1, NM_001164692.2 [Q9NPC1-2] NP_062813.2, NM_019839.4 [Q9NPC1-2]
UniGeneⁱ	Hs.642693 Hs.657595

Genome annotation databases

Ensemblⁱ	ENST00000528054; ENSP00000432146; ENSG00000213906 [Q9NPC1-1] ENST00000533293; ENSP00000433290; ENSG00000213906 [Q9NPC1-2] ENST00000543919; ENSP00000445772; ENSG00000213906 [Q9NPC1-2] ENST00000643080; ENSP00000494694; ENSG00000285203 [Q9NPC1-2] ENST00000644309; ENSP00000494877; ENSG00000285203 [Q9NPC1-2] ENST00000645084; ENSP00000496382; ENSG00000285203 [Q9NPC1-1]
GeneIDⁱ	56413
KEGGⁱ	hsa:56413
UCSC genome browser More...UCSCⁱ	uc001wor.4 human [Q9NPC1-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9NPC1	Isoform 2 of Leukotriene B4 receptor 2		HUMAN		358	UniRef100_Q9NPC1
Leukotriene B4 receptor 2 (Fragment)		HUMAN		319
Leukotriene B4 receptor 2 (Fragment)		HUMAN		160

Protein	Similar proteins		Species	Score	Length	Source
Q9NPC1	Leukotriene B4 receptor 2		MOUSE		360	UniRef90_Q9NPC1
Isoform 2 of Leukotriene B4 receptor 2		HUMAN		358
LTB4R2 isoform 2		PANTR		389
Leukotriene B4 receptor 2		GORGO		389
LTB4R2 isoform 5 (Fragment)		PONAB		160
+43

Protein	Similar proteins		Species	Score	Length	Source
Q9NPC1	Leukotriene B4 receptor 2		MOUSE		360	UniRef50_Q9NPC1
Leukotriene B4 receptor 2		RAT		358
Isoform 2 of Leukotriene B4 receptor 2		HUMAN		358
Uncharacterized protein		AOTNA		389
Uncharacterized protein		MACFA		389
+118

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF277230 mRNA Translation: AAF81261.1 AB029892 mRNA Translation: BAA99553.1 AB008193 Genomic DNA Translation: BAB00610.1 Different initiation. AB032558 mRNA Translation: BAD83590.1 AJ278605 Genomic DNA Translation: CAB96134.1 AY268433 Genomic DNA Translation: AAP23200.1 AL096870 Genomic DNA No translation available. CH471078 Genomic DNA Translation: EAW66030.1 AF308571 mRNA Translation: AAG40857.1 AB044402 mRNA Translation: BAA99539.1 AB083604 Genomic DNA Translation: BAB89317.1
CCDSⁱ	CCDS9625.2 [Q9NPC1-2]
PIRⁱ	JC7356
RefSeqⁱ	NP_001158164.1, NM_001164692.2 [Q9NPC1-2] NP_062813.2, NM_019839.4 [Q9NPC1-2]
UniGeneⁱ	Hs.642693 Hs.657595

3D structure databases

ProteinModelPortalⁱ	Q9NPC1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	121143, 4 interactors
IntActⁱ	Q9NPC1, 1 interactor
MINTⁱ	Q9NPC1
STRINGⁱ	9606.ENSP00000433290

Chemistry databases

BindingDBⁱ	Q9NPC1
ChEMBLⁱ	CHEMBL3191
GuidetoPHARMACOLOGYⁱ	268
SwissLipidsⁱ	SLP:000001556

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	Q9NPC1
PhosphoSitePlusⁱ	Q9NPC1

Polymorphism and mutation databases

BioMutaⁱ	LTB4R2
DMDMⁱ	23821812

Proteomic databases

EPDⁱ	Q9NPC1
PaxDbⁱ	Q9NPC1
PRIDEⁱ	Q9NPC1
ProteomicsDBⁱ	81963

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	56413
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000528054; ENSP00000432146; ENSG00000213906 [Q9NPC1-1] ENST00000533293; ENSP00000433290; ENSG00000213906 [Q9NPC1-2] ENST00000543919; ENSP00000445772; ENSG00000213906 [Q9NPC1-2] ENST00000643080; ENSP00000494694; ENSG00000285203 [Q9NPC1-2] ENST00000644309; ENSP00000494877; ENSG00000285203 [Q9NPC1-2] ENST00000645084; ENSP00000496382; ENSG00000285203 [Q9NPC1-1]
GeneIDⁱ	56413
KEGGⁱ	hsa:56413
UCSCⁱ	uc001wor.4 human [Q9NPC1-1]

Organism-specific databases

CTDⁱ	56413
DisGeNETⁱ	56413
EuPathDBⁱ	HostDB:ENSG00000213906.9
GeneCardsⁱ	LTB4R2
H-InvDBⁱ	HIX0131234
HGNCⁱ	HGNC:19260 LTB4R2
HPAⁱ	CAB022689 HPA029680 HPA072921
MIMⁱ	605773 gene
neXtProtⁱ	NX_Q9NPC1
OpenTargetsⁱ	ENSG00000213906
PharmGKBⁱ	PA134910672
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
GeneTreeⁱ	ENSGT00920000149097
HOGENOMⁱ	HOG000008594
HOVERGENⁱ	HBG104134
InParanoidⁱ	Q9NPC1
KOⁱ	K04297
OMAⁱ	SREGTME
OrthoDBⁱ	EOG091G0G5V
PhylomeDBⁱ	Q9NPC1
TreeFamⁱ	TF330976

Enzyme and pathway databases

Reactomeⁱ	R-HSA-391906 Leukotriene receptors R-HSA-416476 G alpha (q) signalling events
SIGNORⁱ	Q9NPC1

Miscellaneous databases

GenomeRNAiⁱ	56413
Protein Ontology More...PROⁱ	PR:Q9NPC1
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000213906 Expressed in 86 organ(s), highest expression level in ectocervix
CleanExⁱ	HS_LTB4R2
ExpressionAtlasⁱ	Q9NPC1 baseline and differential
Genevisibleⁱ	Q9NPC1 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR003981 Leukotriene_B4_rcpt IPR003982 Leukotriene_B4_typ-2_rcpt
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01478 LTB2RECEPTOR PR01476 LTBRECEPTOR
PROSITEⁱ	View protein in PROSITE PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	LT4R2_HUMAN
Accessionⁱ	Q9NPC1Primary (citable) accession number: Q9NPC1 Secondary accession number(s): Q5KU28, Q9NPE5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
	Last sequence update:	October 1, 2000
	Last modified:	September 12, 2018
	This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM
SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries

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UniProtKB - Q9NPC1 (LT4R2_HUMAN)

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Leukotriene B4 receptor 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Chemistry databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Nucleus

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ