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Protein

Nucleolar protein of 40 kDa

Gene

ZCCHC17

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri131 – 148CCHC-typePROSITE-ProRule annotationAdd BLAST18

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar protein of 40 kDa
Short name:
pNO40
Alternative name(s):
Pnn-interacting nucleolar protein
Putative S1 RNA-binding domain protein
Short name:
PS1D protein
Zinc finger CCHC domain-containing protein 17
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZCCHC17
Synonyms:PS1D
ORF Names:HSPC243, HSPC251, LDC4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000121766.14

Human Gene Nomenclature Database

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HGNCi
HGNC:30246 ZCCHC17

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NP64

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000121766

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670539

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
73921227

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000969021 – 241Nucleolar protein of 40 kDaAdd BLAST241

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei114PhosphoserineCombined sources1
Modified residuei144N6-acetyllysineBy similarity1
Modified residuei183PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
Q9NP64

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9NP64

PeptideAtlas

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PeptideAtlasi
Q9NP64

PRoteomics IDEntifications database

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PRIDEi
Q9NP64

ProteomicsDB human proteome resource

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ProteomicsDBi
81894
81895 [Q9NP64-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q9NP64

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q9NP64

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000121766 Expressed in 198 organ(s), highest expression level in C1 segment of cervical spinal cord

CleanEx database of gene expression profiles

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CleanExi
HS_ZCCHC17

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9NP64 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9NP64 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053727

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PNN. Associates with the 60S ribosomal subunit (By similarity).By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
119598, 57 interactors

Protein interaction database and analysis system

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IntActi
Q9NP64, 27 interactors

Molecular INTeraction database

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MINTi
Q9NP64

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000343557

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1241
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q9NP64

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9NP64

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9NP64

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 88S1 motifPROSITE-ProRule annotationAdd BLAST73

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi110 – 113Poly-Arg4
Compositional biasi161 – 167Poly-Glu7
Compositional biasi185 – 240Lys-richAdd BLAST56

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri131 – 148CCHC-typePROSITE-ProRule annotationAdd BLAST18

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410INHE Eukaryota
COG1185 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00510000047363

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113809

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG080343

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9NP64

Database for complete collections of gene phylogenies

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PhylomeDBi
Q9NP64

TreeFam database of animal gene trees

More...
TreeFami
TF332136

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR012340 NA-bd_OB-fold
IPR037320 pNO40
IPR022967 S1_dom
IPR003029 S1_domain
IPR001878 Znf_CCHC

The PANTHER Classification System

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PANTHERi
PTHR15838 PTHR15838, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00575 S1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00316 S1, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF50249 SSF50249, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS50126 S1, 1 hit
PS50158 ZF_CCHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NP64-1) [UniParc]FASTAAdd to basket
Also known as: hpNO40

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNSGRPETME NLPALYTIFQ GEVAMVTDYG AFIKIPGCRK QGLVHRTHMS
60 70 80 90 100
SCRVDKPSEI VDVGDKVWVK LIGREMKNDR IKVSLSMKVV NQGTGKDLDP
110 120 130 140 150
NNVIIEQEER RRRSFQDYTG QKITLEAVLN TTCKKCGCKG HFAKDCFMQP
160 170 180 190 200
GGTKYSLIPD EEEEKEEAKS AEFEKPDPTR NPSRKRKKEK KKKKHRDRKS
210 220 230 240
SDSDSSDSES DTGKRARHTS KDSKAAKKKK KKKKHKKKHK E
Length:241
Mass (Da):27,570
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA1B039DAC5F4A1D
GO
Isoform 2 (identifier: Q9NP64-2) [UniParc]FASTAAdd to basket
Also known as: hpNO40s

The sequence of this isoform differs from the canonical sequence as follows:
     1-24: Missing.

Show »
Length:217
Mass (Da):24,919
Checksum:i9082B1330EE4DAAF
GO
Isoform 3 (identifier: Q9NP64-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-22: MNSGRPETMENLPALYTIFQGE → MKQLIEDTEKNKVY

Note: No experimental confirmation available.
Show »
Length:233
Mass (Da):26,810
Checksum:iB474CB5DC1AF7600
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WXF8A0A087WXF8_HUMAN
Nucleolar protein of 40 kDa
ZCCHC17
263Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYV3A0A087WYV3_HUMAN
Nucleolar protein of 40 kDa
ZCCHC17
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WXU5A0A087WXU5_HUMAN
Nucleolar protein of 40 kDa
ZCCHC17
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0D9SEW3A0A0D9SEW3_HUMAN
Nucleolar protein of 40 kDa
ZCCHC17
243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYF0A0A087WYF0_HUMAN
Nucleolar protein of 40 kDa
ZCCHC17
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF36171 differs from that shown. Reason: Frameshift at position 48.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti217R → G in AAF36171 (PubMed:11042152).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0153081 – 24Missing in isoform 2. 1 PublicationAdd BLAST24
Alternative sequenceiVSP_0545311 – 22MNSGR…IFQGE → MKQLIEDTEKNKVY in isoform 3. 1 PublicationAdd BLAST22

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF247661 mRNA Translation: AAF72518.3
AF151077 mRNA Translation: AAF36163.1
AF151085 mRNA Translation: AAF36171.1 Frameshift.
AK001929 mRNA Translation: BAA91984.1
AK022506 mRNA Translation: BAB14066.1
AK024049 mRNA Translation: BAB14799.1
AK302248 mRNA Translation: BAG63600.1
AL451070 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07620.1
CH471059 Genomic DNA Translation: EAX07621.1
CH471059 Genomic DNA Translation: EAX07622.1
CH471059 Genomic DNA Translation: EAX07624.1
BC000685 mRNA Translation: AAH00685.1
BC007446 mRNA Translation: AAH07446.1
BC050609 mRNA Translation: AAH50609.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS341.1 [Q9NP64-1]
CCDS60061.1 [Q9NP64-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001269495.1, NM_001282566.1
NP_001269496.1, NM_001282567.1
NP_001269497.1, NM_001282568.1 [Q9NP64-1]
NP_001269498.1, NM_001282569.1 [Q9NP64-3]
NP_001269499.1, NM_001282570.1 [Q9NP64-2]
NP_001269500.1, NM_001282571.1
NP_001269501.1, NM_001282572.1
NP_001269502.1, NM_001282573.1
NP_001269503.1, NM_001282574.1
NP_057589.2, NM_016505.3 [Q9NP64-1]
XP_006710744.1, XM_006710681.3 [Q9NP64-3]
XP_011539869.1, XM_011541567.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.524094

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000344147; ENSP00000343557; ENSG00000121766 [Q9NP64-1]
ENST00000373714; ENSP00000362819; ENSG00000121766 [Q9NP64-1]
ENST00000546109; ENSP00000444742; ENSG00000121766 [Q9NP64-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
51538

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:51538

UCSC genome browser

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UCSCi
uc001bsp.3 human [Q9NP64-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF247661 mRNA Translation: AAF72518.3
AF151077 mRNA Translation: AAF36163.1
AF151085 mRNA Translation: AAF36171.1 Frameshift.
AK001929 mRNA Translation: BAA91984.1
AK022506 mRNA Translation: BAB14066.1
AK024049 mRNA Translation: BAB14799.1
AK302248 mRNA Translation: BAG63600.1
AL451070 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07620.1
CH471059 Genomic DNA Translation: EAX07621.1
CH471059 Genomic DNA Translation: EAX07622.1
CH471059 Genomic DNA Translation: EAX07624.1
BC000685 mRNA Translation: AAH00685.1
BC007446 mRNA Translation: AAH07446.1
BC050609 mRNA Translation: AAH50609.1
CCDSiCCDS341.1 [Q9NP64-1]
CCDS60061.1 [Q9NP64-3]
RefSeqiNP_001269495.1, NM_001282566.1
NP_001269496.1, NM_001282567.1
NP_001269497.1, NM_001282568.1 [Q9NP64-1]
NP_001269498.1, NM_001282569.1 [Q9NP64-3]
NP_001269499.1, NM_001282570.1 [Q9NP64-2]
NP_001269500.1, NM_001282571.1
NP_001269501.1, NM_001282572.1
NP_001269502.1, NM_001282573.1
NP_001269503.1, NM_001282574.1
NP_057589.2, NM_016505.3 [Q9NP64-1]
XP_006710744.1, XM_006710681.3 [Q9NP64-3]
XP_011539869.1, XM_011541567.2
UniGeneiHs.524094

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQONMR-A1-106[»]
ProteinModelPortaliQ9NP64
SMRiQ9NP64
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119598, 57 interactors
IntActiQ9NP64, 27 interactors
MINTiQ9NP64
STRINGi9606.ENSP00000343557

PTM databases

iPTMnetiQ9NP64
PhosphoSitePlusiQ9NP64

Polymorphism and mutation databases

DMDMi73921227

Proteomic databases

MaxQBiQ9NP64
PaxDbiQ9NP64
PeptideAtlasiQ9NP64
PRIDEiQ9NP64
ProteomicsDBi81894
81895 [Q9NP64-2]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
51538
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344147; ENSP00000343557; ENSG00000121766 [Q9NP64-1]
ENST00000373714; ENSP00000362819; ENSG00000121766 [Q9NP64-1]
ENST00000546109; ENSP00000444742; ENSG00000121766 [Q9NP64-3]
GeneIDi51538
KEGGihsa:51538
UCSCiuc001bsp.3 human [Q9NP64-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
51538
EuPathDBiHostDB:ENSG00000121766.14

GeneCards: human genes, protein and diseases

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GeneCardsi
ZCCHC17
HGNCiHGNC:30246 ZCCHC17
HPAiHPA053727
neXtProtiNX_Q9NP64
OpenTargetsiENSG00000121766
PharmGKBiPA142670539

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410INHE Eukaryota
COG1185 LUCA
GeneTreeiENSGT00510000047363
HOGENOMiHOG000113809
HOVERGENiHBG080343
InParanoidiQ9NP64
PhylomeDBiQ9NP64
TreeFamiTF332136

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZCCHC17 human
EvolutionaryTraceiQ9NP64

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ZCCHC17

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51538

Protein Ontology

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PROi
PR:Q9NP64

Gene expression databases

BgeeiENSG00000121766 Expressed in 198 organ(s), highest expression level in C1 segment of cervical spinal cord
CleanExiHS_ZCCHC17
ExpressionAtlasiQ9NP64 baseline and differential
GenevisibleiQ9NP64 HS

Family and domain databases

InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR037320 pNO40
IPR022967 S1_dom
IPR003029 S1_domain
IPR001878 Znf_CCHC
PANTHERiPTHR15838 PTHR15838, 1 hit
PfamiView protein in Pfam
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit
PS50158 ZF_CCHC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNO40_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NP64
Secondary accession number(s): B4DY38
, D3DPN4, Q6PKH4, Q9NYG4, Q9P0M8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: October 1, 2000
Last modified: October 10, 2018
This is version 157 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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