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Protein

Protein Wnt

Gene

Wnt8

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:Wnt8Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500433173223 – 364Protein WntSequence analysisAdd BLAST342

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
HOVERGENiHBG001595

Family and domain databases

InterProiView protein in InterPro
IPR034311 Protein_Wnt-8B
IPR005817 Wnt
IPR013301 Wnt8
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PTHR12027:SF94 PTHR12027:SF94, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01892 WNT8PROTEIN
PR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9NCP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAQLLWSLS VLLAALSGTA DSNGWTLQSN FLITGPKSSF QASLTYASSV
60 70 80 90 100
AAGAQTAMEE CKHQFSWDRW NCTDNALSMF KPNTLPANRE ASFVHAISAA
110 120 130 140 150
GVMYVLTRNC SKGAFEQCGC DLTNNGKKAE GGWTWGGCSD DIAFGERISK
160 170 180 190 200
MYSDGVENGQ DARAAMNLHN NDVGRKAVRQ TMKRVCKCHG VSGSCTTKTC
210 220 230 240 250
WLQLADFRAI GVFLKKKYKK ADKVDYVRGQ LTENNSASSK RNTGLKKDMV
260 270 280 290 300
FLEDSPDYCR ENLTVGSRGT LGRECLRGGG KNMDKYEKKS CKRLCKDCGY
310 320 330 340 350
VPKRITTEVT SSCNCKFHWC CSVKCSQCTK TVTKYICVQR ESSKNRRKNV
360
RKKSKQRRRN RGNN
Length:364
Mass (Da):40,514
Last modified:October 1, 2000 - v1
Checksum:i12C105C3CCD45D60
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF190470 mRNA Translation: AAF80559.1

Similar proteinsi

Entry informationi

Entry nameiQ9NCP9_BRAFL
AccessioniPrimary (citable) accession number: Q9NCP9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: June 20, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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