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Protein
Submitted name:

Falcipain 2

Gene
N/A
Organism
Plasmodium falciparum
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-15378
BRENDAi3.4.22.B69 4889
SABIO-RKiQ9N6S8

Protein family/group databases

MEROPSiC01.046

Names & Taxonomyi

Protein namesi
Submitted name:
Falcipain 2Imported
OrganismiPlasmodium falciparumImported
Taxonomic identifieri5833 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 55HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5800

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi282 ↔ 323Combined sources
Disulfide bondi316 ↔ 357Combined sources
Disulfide bondi342 ↔ 362Combined sources
Disulfide bondi411 ↔ 472Combined sources

Interactioni

Protein-protein interaction databases

DIPiDIP-59137N
IntActiQ9N6S8, 2 interactors

Structurei

3D structure databases

SMRiQ9N6S8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini165 – 222Inhibitor_I29InterPro annotationAdd BLAST58
Domaini261 – 482Pept_C1InterPro annotationAdd BLAST222

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1543 Eukaryota
COG4870 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR013201 Prot_inhib_I29
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF08246 Inhibitor_I29, 1 hit
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00848 Inhibitor_I29, 1 hit
SM00645 Pept_C1, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

Q9N6S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYNMDYAPH EVISQQGERF VDKYVDRKIL KNKKSLLVII SLSVLSVVGF
60 70 80 90 100
VLFYFTPNSR KSDLFKNSSV ENNNDDYIIN SLLKSPNGKK FIVSKIDEAL
110 120 130 140 150
SFYDSKKNDI NKYNEGNNNN NADFKGLSLF KENTPSNNFI HNKDYFINFF
160 170 180 190 200
DNKFLMNNAE HINQFYMFIK TNNKQYNSPN EMKERFQVFL QNAHKVNMHN
210 220 230 240 250
NNKNSLYKKE LNRFADLTYH EFKNKYLSLR SSKPLKNSKY LLDQMNYEEV
260 270 280 290 300
IKKYRGEENF DHAAYDWRLH SGVTPVKDQK NCGSCWAFSS IGSVESQYAI
310 320 330 340 350
RKNKLITLSE QELVDCSFKN YGCNGGLINN AFEDMIELGG ICPDGDYPYV
360 370 380 390 400
SDAPNLCNID RCTEKYGIKN YLSVPDNKLK EALRFLGPIS ISVAVSDDFA
410 420 430 440 450
FYKEGIFDGE CGDQLNHAVM LVGFGMKEIV NPLTKKGEKH YYYIIKNSWG
460 470 480
QQWGERGFIN IETDESGLMR KCGLGTDAFI PLIE
Length:484
Mass (Da):55,908
Last modified:October 1, 2000 - v1
Checksum:i092960919F4D43C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF239801 mRNA Translation: AAF63497.1
AF282975 Genomic DNA Translation: AAF97805.1
AF282976 Genomic DNA Translation: AAF97806.1
AF282977 Genomic DNA Translation: AAF97807.1

Similar proteinsi

Entry informationi

Entry nameiQ9N6S8_PLAFA
AccessioniPrimary (citable) accession number: Q9N6S8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: June 20, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

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