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Entry version 145 (26 Feb 2020)
Sequence version 1 (01 Oct 2000)
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Protein

Homeobox protein unc-62

Gene

unc-62

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi392 – 454Homeobox; TALE-typePROSITE-ProRule annotationAdd BLAST63

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Homeobox protein unc-62
Alternative name(s):
Uncoordinated protein 62
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:unc-62
ORF Names:T28F12.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

Organism-specific databases

WormBase

More...
WormBasei
T28F12.2a ; CE21219 ; WBGene00006796 ; unc-62
T28F12.2b ; CE21220 ; WBGene00006796 ; unc-62
T28F12.2c ; CE31073 ; WBGene00006796 ; unc-62
T28F12.2d ; CE31074 ; WBGene00006796 ; unc-62
T28F12.2e ; CE33584 ; WBGene00006796 ; unc-62
T28F12.2f ; CE33585 ; WBGene00006796 ; unc-62
T28F12.2g ; CE37795 ; WBGene00006796 ; unc-62

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Worms exhibit severe posterior disorganization during embryogenesis (Nob phenotype). Mutants exhibit Q cell migration defects, affecting cell position along the anterior posterior axis.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003414831 – 564Homeobox protein unc-62Add BLAST564

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9N5D6

PeptideAtlas

More...
PeptideAtlasi
Q9N5D6

PRoteomics IDEntifications database

More...
PRIDEi
Q9N5D6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically. Isoform a and isoform f are more abundant than isoform b and isoform e, but their temporal patterns of accumulation are similar. All are present in adult germline, pregastrulation embryos, later embryos and adult soma.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006796 Expressed in multi-cellular organism and 3 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
43897, 15 interactors

Database of interacting proteins

More...
DIPi
DIP-26061N

Protein interaction database and analysis system

More...
IntActi
Q9N5D6, 80 interactors

STRING: functional protein association networks

More...
STRINGi
6239.T28F12.2a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9N5D6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TALE/MEIS homeobox family.Sequence analysis

Keywords - Domaini

Homeobox

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0773 Eukaryota
ENOG410XPMQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000168996

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9N5D6

Identification of Orthologs from Complete Genome Data

More...
OMAi
AATAMHY

Database of Orthologous Groups

More...
OrthoDBi
1126341at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9N5D6

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00086 homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR008422 Homeobox_KN_domain
IPR032453 PKNOX/Meis_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05920 Homeobox_KN, 1 hit
PF16493 Meis_PKNOX_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00389 HOX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 7 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 7 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform a1 Publication (identifier: Q9N5D6-1) [UniParc]FASTAAdd to basket
Also known as: 1a-7b1 Publication

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGDSKVWAH ASADTWAVQN GISTYDLDTS SIKREKRDHN EQFNDGYGPP
60 70 80 90 100
PGSASADPAS YIADPAAFYN LYTNMGGAPT STPMMHHEMG EAMKRDKESI
110 120 130 140 150
YAHPLYPLLV LLFEKCELAT STPRDTSRDG STSSDVCSSA SFKDDLNEFV
160 170 180 190 200
RHTQENADKQ YYVPNPQLDQ IMLQSIQMLR FHLLELEKVH ELCDNFCNRY
210 220 230 240 250
VVCLKGKMPL DIVGDERASS SQPPMSPGSM GHLGHSSSPS MAGGATPMHY
260 270 280 290 300
PPPYEPQSVP LPENAGVMGG HPMEGSSMAY SMAGMAAAAA SSSSSSNQAG
310 320 330 340 350
DHPLANGGTL HSTAGASQTL LPIAVSSPST CSSGGLRQDS TPLSGETPMG
360 370 380 390 400
HANGNSMDSI SEAGDEFSVC GSNDDGRDSV LSDSANGSQN GKRKVPKVFS
410 420 430 440 450
KEAITKFRAW LFHNLTHPYP SEEQKKQLAK ETGLTILQVN NWFINARRRI
460 470 480 490 500
VQPMIDQNNR AGRSGQMNVC KNRRRNRSEQ SPGPSPDSGS DSGANYSPDP
510 520 530 540 550
SSLAASTAMP YPAEFYMQRT MPYGGFPSFT NPAMPFMNPM MGFQVAPTVD
560
ALSQQWVDLS APHE
Length:564
Mass (Da):60,889
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1CA94964980BC2C5
GO
Isoform b1 Publication (identifier: Q9N5D6-2) [UniParc]FASTAAdd to basket
Also known as: 1b-7b1 Publication

The sequence of this isoform differs from the canonical sequence as follows:
     2-41: SGDSKVWAHASADTWAVQNGISTYDLDTSSIKREKRDHNE → AQR

Show »
Length:527
Mass (Da):56,785
Checksum:i49390A493D81DA85
GO
Isoform c1 Publication (identifier: Q9N5D6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2-5: SGDS → FNFQ
     6-416: Missing.

Show »
Length:153
Mass (Da):17,176
Checksum:i06AE2E6B0E999BF0
GO
Isoform d1 Publication (identifier: Q9N5D6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-453: Missing.

Show »
Length:111
Mass (Da):12,122
Checksum:iA87026EDEFA9299C
GO
Isoform e1 Publication (identifier: Q9N5D6-5) [UniParc]FASTAAdd to basket
Also known as: 1b-7a1 Publication

The sequence of this isoform differs from the canonical sequence as follows:
     2-41: SGDSKVWAHASADTWAVQNGISTYDLDTSSIKREKRDHNE → AQR
     364-413: GDEFSVCGSN...ITKFRAWLFH → APSSASSSSS...TNRLRQWLFQ

Show »
Length:523
Mass (Da):56,228
Checksum:i43F69CB21F2BF174
GO
Isoform f1 Publication (identifier: Q9N5D6-6) [UniParc]FASTAAdd to basket
Also known as: 1a-7a1 Publication

The sequence of this isoform differs from the canonical sequence as follows:
     364-413: GDEFSVCGSN...ITKFRAWLFH → APSSASSSSS...TNRLRQWLFQ

Show »
Length:560
Mass (Da):60,331
Checksum:i067C84F274B9CBEE
GO
Isoform g1 Publication (identifier: Q9N5D6-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-74: Missing.

Show »
Length:490
Mass (Da):52,864
Checksum:iD49161AD4AE797EF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0K3ASC5A0A0K3ASC5_CAEEL
Homeobox domain-containing protein
unc-62 CELE_T28F12.2, T28F12.2
486Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0528271 – 453Missing in isoform d. 1 PublicationAdd BLAST453
Alternative sequenceiVSP_0528281 – 74Missing in isoform g. 1 PublicationAdd BLAST74
Alternative sequenceiVSP_0528292 – 41SGDSK…RDHNE → AQR in isoform b and isoform e. 1 PublicationAdd BLAST40
Alternative sequenceiVSP_0528302 – 5SGDS → FNFQ in isoform c. 1 Publication4
Alternative sequenceiVSP_0528316 – 416Missing in isoform c. 1 PublicationAdd BLAST411
Alternative sequenceiVSP_052832364 – 413GDEFS…AWLFH → APSSASSSSSSKNKPSTPNG GRIGKSRGRGIFPKQATNRL RQWLFQ in isoform e and isoform f. 1 PublicationAdd BLAST50

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF427474 mRNA Translation: AAL65142.1
AF427475 mRNA Translation: AAL65143.1
AF427476 mRNA Translation: AAL65144.1
AF427477 mRNA Translation: AAL65145.1
FO081534 Genomic DNA Translation: CCD72261.1
FO081534 Genomic DNA Translation: CCD72262.1
FO081534 Genomic DNA Translation: CCD72263.1
FO081534 Genomic DNA Translation: CCD72264.1
FO081534 Genomic DNA Translation: CCD72265.1
FO081534 Genomic DNA Translation: CCD72266.1
FO081534 Genomic DNA Translation: CCD72267.1

NCBI Reference Sequences

More...
RefSeqi
NP_001024169.1, NM_001028998.2 [Q9N5D6-1]
NP_001024170.1, NM_001028999.2 [Q9N5D6-2]
NP_001024171.1, NM_001029000.1 [Q9N5D6-3]
NP_001024172.1, NM_001029001.2
NP_001024173.1, NM_001029002.2 [Q9N5D6-5]
NP_001024174.1, NM_001029003.2 [Q9N5D6-6]
NP_001024175.1, NM_001029004.3 [Q9N5D6-7]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
T28F12.2a.1; T28F12.2a.1; WBGene00006796 [Q9N5D6-1]
T28F12.2a.2; T28F12.2a.2; WBGene00006796 [Q9N5D6-1]
T28F12.2b.1; T28F12.2b.1; WBGene00006796 [Q9N5D6-2]
T28F12.2b.2; T28F12.2b.2; WBGene00006796 [Q9N5D6-2]
T28F12.2c.1; T28F12.2c.1; WBGene00006796 [Q9N5D6-3]
T28F12.2d.1; T28F12.2d.1; WBGene00006796 [Q9N5D6-4]
T28F12.2e.1; T28F12.2e.1; WBGene00006796 [Q9N5D6-5]
T28F12.2f.1; T28F12.2f.1; WBGene00006796 [Q9N5D6-6]
T28F12.2g.1; T28F12.2g.1; WBGene00006796 [Q9N5D6-7]

Database of genes from NCBI RefSeq genomes

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GeneIDi
178845

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_T28F12.2

UCSC genome browser

More...
UCSCi
T28F12.2a.1 c. elegans [Q9N5D6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF427474 mRNA Translation: AAL65142.1
AF427475 mRNA Translation: AAL65143.1
AF427476 mRNA Translation: AAL65144.1
AF427477 mRNA Translation: AAL65145.1
FO081534 Genomic DNA Translation: CCD72261.1
FO081534 Genomic DNA Translation: CCD72262.1
FO081534 Genomic DNA Translation: CCD72263.1
FO081534 Genomic DNA Translation: CCD72264.1
FO081534 Genomic DNA Translation: CCD72265.1
FO081534 Genomic DNA Translation: CCD72266.1
FO081534 Genomic DNA Translation: CCD72267.1
RefSeqiNP_001024169.1, NM_001028998.2 [Q9N5D6-1]
NP_001024170.1, NM_001028999.2 [Q9N5D6-2]
NP_001024171.1, NM_001029000.1 [Q9N5D6-3]
NP_001024172.1, NM_001029001.2
NP_001024173.1, NM_001029002.2 [Q9N5D6-5]
NP_001024174.1, NM_001029003.2 [Q9N5D6-6]
NP_001024175.1, NM_001029004.3 [Q9N5D6-7]

3D structure databases

SMRiQ9N5D6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi43897, 15 interactors
DIPiDIP-26061N
IntActiQ9N5D6, 80 interactors
STRINGi6239.T28F12.2a

Proteomic databases

PaxDbiQ9N5D6
PeptideAtlasiQ9N5D6
PRIDEiQ9N5D6

Genome annotation databases

EnsemblMetazoaiT28F12.2a.1; T28F12.2a.1; WBGene00006796 [Q9N5D6-1]
T28F12.2a.2; T28F12.2a.2; WBGene00006796 [Q9N5D6-1]
T28F12.2b.1; T28F12.2b.1; WBGene00006796 [Q9N5D6-2]
T28F12.2b.2; T28F12.2b.2; WBGene00006796 [Q9N5D6-2]
T28F12.2c.1; T28F12.2c.1; WBGene00006796 [Q9N5D6-3]
T28F12.2d.1; T28F12.2d.1; WBGene00006796 [Q9N5D6-4]
T28F12.2e.1; T28F12.2e.1; WBGene00006796 [Q9N5D6-5]
T28F12.2f.1; T28F12.2f.1; WBGene00006796 [Q9N5D6-6]
T28F12.2g.1; T28F12.2g.1; WBGene00006796 [Q9N5D6-7]
GeneIDi178845
KEGGicel:CELE_T28F12.2
UCSCiT28F12.2a.1 c. elegans [Q9N5D6-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
178845
WormBaseiT28F12.2a ; CE21219 ; WBGene00006796 ; unc-62
T28F12.2b ; CE21220 ; WBGene00006796 ; unc-62
T28F12.2c ; CE31073 ; WBGene00006796 ; unc-62
T28F12.2d ; CE31074 ; WBGene00006796 ; unc-62
T28F12.2e ; CE33584 ; WBGene00006796 ; unc-62
T28F12.2f ; CE33585 ; WBGene00006796 ; unc-62
T28F12.2g ; CE37795 ; WBGene00006796 ; unc-62

Phylogenomic databases

eggNOGiKOG0773 Eukaryota
ENOG410XPMQ LUCA
GeneTreeiENSGT00940000168996
InParanoidiQ9N5D6
OMAiAATAMHY
OrthoDBi1126341at2759
PhylomeDBiQ9N5D6

Miscellaneous databases

Protein Ontology

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PROi
PR:Q9N5D6

Gene expression databases

BgeeiWBGene00006796 Expressed in multi-cellular organism and 3 other tissues

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR008422 Homeobox_KN_domain
IPR032453 PKNOX/Meis_N
PfamiView protein in Pfam
PF05920 Homeobox_KN, 1 hit
PF16493 Meis_PKNOX_N, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUNC62_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9N5D6
Secondary accession number(s): Q5TKQ8
, Q8MXU6, Q8MXU7, Q8WRQ5, Q8WRQ6, Q9N5D5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 1, 2000
Last modified: February 26, 2020
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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