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Protein

40S ribosomal protein S4

Gene

rps-4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-CEL-72702 Ribosomal scanning and start codon recognition
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:rps-4
ORF Names:Y43B11AR.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY43B11AR.4 ; CE24278 ; WBGene00004473 ; rps-4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001308301 – 25940S ribosomal protein S4Add BLAST259

Proteomic databases

EPDiQ9N3X2
PaxDbiQ9N3X2
PeptideAtlasiQ9N3X2
PRIDEiQ9N3X2

PTM databases

iPTMnetiQ9N3X2

Expressioni

Gene expression databases

BgeeiWBGene00004473

Interactioni

Protein-protein interaction databases

BioGridi42600, 3 interactors
DIPiDIP-24988N
IntActiQ9N3X2, 2 interactors
STRINGi6239.Y43B11AR.4.1

Structurei

3D structure databases

ProteinModelPortaliQ9N3X2
SMRiQ9N3X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 100S4 RNA-bindingAdd BLAST60

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eS4 family.Sequence analysis

Phylogenomic databases

eggNOGiKOG0378 Eukaryota
COG1471 LUCA
GeneTreeiENSGT00390000005569
HOGENOMiHOG000231325
InParanoidiQ9N3X2
KOiK02987
OMAiRKDYKFP
OrthoDBiEOG091G0MYF
PhylomeDBiQ9N3X2

Family and domain databases

Gene3Di2.30.30.30, 1 hit
2.40.50.740, 1 hit
HAMAPiMF_00485 Ribosomal_S4e, 1 hit
InterProiView protein in InterPro
IPR032277 40S_S4_C
IPR014722 Rib_L2_dom2
IPR000876 Ribosomal_S4e
IPR013845 Ribosomal_S4e_central_region
IPR038237 Ribosomal_S4e_central_sf
IPR013843 Ribosomal_S4e_N
IPR018199 Ribosomal_S4e_N_CS
PANTHERiPTHR11581 PTHR11581, 1 hit
PfamiView protein in Pfam
PF16121 40S_S4_C, 1 hit
PF00900 Ribosomal_S4e, 1 hit
PF08071 RS4NT, 1 hit
PIRSFiPIRSF002116 Ribosomal_S4, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667 Ribosomal_S4e_central, 1 hit
PROSITEiView protein in PROSITE
PS00528 RIBOSOMAL_S4E, 1 hit

Sequencei

Sequence statusi: Complete.

Q9N3X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGPKKHLKR LAAPSHWMLD KLGGVFAVRP NPGPHKLRES LPLSLFLRNR
60 70 80 90 100
LKYALNYTEA KKILTQRVVR VDGKVRTCHK FPTGFMDVVA IERTNEYFRM
110 120 130 140 150
LYDTKGRYVV HRIQAAEADF KLCKVKSVRT VNKGVPVLTT TDGRTIRYPD
160 170 180 190 200
PHVKVNDTIV FNISTQKITD SVKFEPGNLA YVTGGRNVGR VGIIGHRERL
210 220 230 240 250
PGASDIIHIK DSAGHSFATR ISNVFVIGKG NKALVSLPTG AGIRLSIAEE

RDKRMAQKH
Length:259
Mass (Da):29,044
Last modified:October 1, 2000 - v1
Checksum:i2A5CA98C640284E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081794 Genomic DNA Translation: CCD74049.1
RefSeqiNP_501103.1, NM_068702.4
UniGeneiCel.11997

Genome annotation databases

EnsemblMetazoaiY43B11AR.4; Y43B11AR.4; WBGene00004473
GeneIDi177481
KEGGicel:CELE_Y43B11AR.4
UCSCiY43B11AR.4.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRS4_CAEEL
AccessioniPrimary (citable) accession number: Q9N3X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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