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Protein
Submitted name:

Nuclear Hormone Receptor family

Gene

nhr-277

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi67 – 142Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear Hormone Receptor familyImported
Gene namesi
Name:nhr-277Imported
ORF Names:CELE_Y94H6A.1Imported, Y94H6A.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY94H6A.1 ; CE34619 ; WBGene00022374 ; nhr-277

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ9N2W3

Expressioni

Gene expression databases

BgeeiWBGene00022374

Interactioni

Protein-protein interaction databases

IntActiQ9N2W3, 1 interactor
STRINGi6239.Y94H6A.1

Structurei

3D structure databases

ProteinModelPortaliQ9N2W3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 142Nuclear receptorInterPro annotationAdd BLAST76
Domaini194 – 467NR LBDInterPro annotationAdd BLAST274

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00870000136388
HOGENOMiHOG000020143
InParanoidiQ9N2W3
OMAiRKGFVCE
OrthoDBiEOG091G0AMN
PhylomeDBiQ9N2W3

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR016355 NR5_fam
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PANTHERiPTHR24086 PTHR24086, 2 hits
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9N2W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTNMLLHAD HHFYSSSQFA SYYQYSQSSQ FFEQMLRESS EIRAPSSGES
60 70 80 90 100
RIPVVGRLKM PPPPPKLKHC EVCGNAGATS HYGGTVCGGC KIFFSRTVQS
110 120 130 140 150
RKGFVCERGG QCPMNAGKRA KCRACRFQLC LKARMSPEEV GRLRDMRMGD
160 170 180 190 200
YLPIVKKEGC VVGYFDESSQ PSTSIEDCTS QVHSFIDTFK YKEDEMSVVN
210 220 230 240 250
IFVNLERSCE NNAALCYRDD FPKTFNASID LQSAMEFPLP ICERIPMDFL
260 270 280 290 300
RKLFLRDPKE NFKLFWCRSV LHFLQWCSAI EDLNYFSRQE RTMLIAENFV
310 320 330 340 350
SIGCLINFYG FLKIQREEFE NCPEDGQIPA PCSAEWFQEL SGLSFEAQTA
360 370 380 390 400
VHRAISEIME PMDSLDVSIE ELVLMKFIMM FSEPSTQTSG DIYRIRSYRL
410 420 430 440 450
KYCELLQKYI KTQIPDPERR IARIGELLKI VEAVKTTSQY FDKWMTMFFA
460 470 480 490
SNTCQMNDVL VYDFHVRMWS DVIPTSTSSS SSSIFATSST LQKIKKEY
Length:498
Mass (Da):57,335
Last modified:October 1, 2003 - v2
Checksum:iAE37B42A9AF70821
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD74201.1
RefSeqiNP_500250.2, NM_067849.2
UniGeneiCel.11723

Genome annotation databases

EnsemblMetazoaiY94H6A.1; Y94H6A.1; WBGene00022374
GeneIDi190799
KEGGicel:CELE_Y94H6A.1
UCSCiY94H6A.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ9N2W3_CAEEL
AccessioniPrimary (citable) accession number: Q9N2W3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2003
Last modified: June 20, 2018
This is version 142 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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