Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 114 (02 Dec 2020)
Sequence version 1 (01 Oct 2000)
Previous versions | rss
Add a publicationFeedback
Protein

Putative pectinesterase/pectinesterase inhibitor 22

Gene

PME22

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts in the modification of cell walls via demethylesterification of cell wall pectin.By similarity

Miscellaneous

The PMEI region may act as an autoinhibitory domain and prevent untimely PME activity during transport.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pectin degradation

This protein is involved in step 1 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase (AN1_LOCUS14650), Pectinesterase (C24_LOCUS25664), Probable pectinesterase/pectinesterase inhibitor 7 (PME7), Pectinesterase (AXX17_At1g11890), Pectinesterase (At5g61680), Pectinesterase (C24_LOCUS11700), Pectinesterase (AXX17_At4g02940), Pectinesterase (AXX17_At5g52320), Pectinesterase (AN1_LOCUS16454), Probable pectinesterase/pectinesterase inhibitor 42 (PME42), Pectinesterase (AN1_LOCUS17324), Probable pectinesterase 15 (PME15), Putative pectinesterase 14 (PME14), Pectinesterase (AT9943_LOCUS3843), Pectinesterase (AN1_LOCUS25396), Pectinesterase (AN1_LOCUS22771), Pectinesterase (AN1_LOCUS25835), Pectinesterase (At3g10720), Pectinesterase (AN1_LOCUS15270), Pectinesterase (AXX17_At2g33410), Pectinesterase (AN1_LOCUS18277), Probable pectinesterase 55 (PME55), Pectinesterase (PMEPCRF), Pectinesterase (AN1_LOCUS8276), Pectinesterase (AXX17_At4g18720), Probable pectinesterase/pectinesterase inhibitor 23 (PME23), Pectinesterase 4 (PME4), Pectinesterase (C24_LOCUS22573), Putative pectinesterase/pectinesterase inhibitor 22 (PME22), Pectinesterase (AXX17_At1g48290), Pectinesterase (C24_LOCUS15150), Pectinesterase (At3g14310), Pectinesterase (AXX17_At5g47900), Pectinesterase (AXX17_At4g38050), Pectinesterase (AT9943_LOCUS10199), Pectinesterase (AXX17_At5g07100), Pectinesterase/pectinesterase inhibitor 18 (PME18), Pectinesterase (AN1_LOCUS25395), Pectinesterase (AXX17_At2g14510), Pectinesterase (AXX17_At3g43380), Pectinesterase (AN1_LOCUS21304), Pectinesterase (AXX17_At5g64270), Pectinesterase (AT9943_LOCUS8684), Probable pectinesterase/pectinesterase inhibitor 64 (PME64), Putative pectinesterase 10 (PME10), Pectinesterase (F14I3.7), Pectinesterase (AT9943_LOCUS18354), Pectinesterase (QRT1), Pectinesterase (At3g49220), Pectinesterase (At3g49220), Pectinesterase (AT9943_LOCUS14009), Pectinesterase, Probable pectinesterase 29 (PME29), Pectinesterase (C24_LOCUS11070), Pectinesterase (AT9943_LOCUS8683), Pectinesterase (C24_LOCUS14263), Pectinesterase (AXX17_At4g38040), Pectinesterase (C24_LOCUS21455), Pectinesterase (C24_LOCUS3675), Pectinesterase (C24_LOCUS5919), Pectinesterase (At5g20860), Probable pectinesterase 8 (PME8), Pectinesterase (AXX17_At5g27870), Pectinesterase (AXX17_At5g26780), Pectinesterase (AXX17_At5g18820), Pectinesterase (C24_LOCUS20040), Pectinesterase (AXX17_At2g45340), Pectinesterase 31 (PME31), Pectinesterase (AXX17_At3g41380), Pectinesterase (AXX17_At1g11650), Probable pectinesterase/pectinesterase inhibitor 25 (PME25), Pectinesterase (C24_LOCUS25225), Pectinesterase (AXX17_At3g36460), Probable pectinesterase/pectinesterase inhibitor 51 (PME51), Pectinesterase (AT9943_LOCUS17388), Pectinesterase (AXX17_At5g04430), Pectinesterase (At3g62170), Pectinesterase (AN1_LOCUS9037), Probable pectinesterase/pectinesterase inhibitor 20 (PME20), Pectinesterase (T27B3.30), Probable pectinesterase/pectinesterase inhibitor 60 (PME60), Pectinesterase (AXX17_At3g53530), Pectinesterase (AXX17_At2g17140), Probable pectinesterase/pectinesterase inhibitor 59 (PME59), Pectinesterase QRT1 (QRT1), Pectinesterase (AN1_LOCUS23521), Pectinesterase (AXX17_At5g61190), Pectinesterase (AN1_LOCUS12387), Pectinesterase (AN1_LOCUS24986), Pectinesterase PPME1 (PPME1), Pectinesterase (AXX17_At3g56460), Pectinesterase (AT9943_LOCUS11913), Pectinesterase (AXX17_At3g06710), Pectinesterase (AN1_LOCUS8540), Pectinesterase (AXX17_At1g44540), Probable pectinesterase/pectinesterase inhibitor 32 (PME32), Probable pectinesterase/pectinesterase inhibitor 33 (PME33), Pectinesterase (AT9943_LOCUS960), Probable pectinesterase/pectinesterase inhibitor 36 (PME36), Pectinesterase (AN1_LOCUS15075), Probable pectinesterase/pectinesterase inhibitor 13 (PME13), Pectinesterase (C24_LOCUS226), Pectinesterase (C24_LOCUS1168), Putative pectinesterase 52 (PME52), Pectinesterase (AT9943_LOCUS10650), Pectinesterase (C24_LOCUS11095), Pectinesterase (C24_LOCUS9969), Probable pectinesterase/pectinesterase inhibitor 54 (PME54), Pectinesterase (C24_LOCUS18162), Pectinesterase (AXX17_At2g33420), Pectinesterase (AXX17_At2g40510), Pectinesterase (At1g53840), Pectinesterase 5 (PME5), Probable pectinesterase/pectinesterase inhibitor 16 (PME16), Probable pectinesterase 30 (PME30), Pectinesterase (PMEPCRA), Probable pectinesterase/pectinesterase inhibitor VGDH2 (VGDH2), Pectinesterase (AXX17_At3g26070), Pectinesterase (AN1_LOCUS16776), Pectinesterase (AT9943_LOCUS19701), Pectinesterase (AT9943_LOCUS9497), Pectinesterase (AN1_LOCUS14598), Pectinesterase (AN1_LOCUS1257), Pectinesterase (AN1_LOCUS580), Pectinesterase (AT9943_LOCUS6486), Pectinesterase, Probable pectinesterase 68 (PME68), Pectinesterase (AXX17_At3g14900), Pectinesterase (AXX17_At5g54740), Pectinesterase (AT9943_LOCUS20258), Pectinesterase (AT9943_LOCUS21699), Probable pectinesterase 67 (PME67), Pectinesterase (AT9943_LOCUS9294), Pectinesterase (AT9943_LOCUS9665), Pectinesterase (C24_LOCUS12217), Putative pectinesterase/pectinesterase inhibitor 38 (PME38), Probable pectinesterase 56 (PME56), Pectinesterase, Pectinesterase (C24_LOCUS8888), Probable pectinesterase/pectinesterase inhibitor 47 (PME47), Putative pectinesterase/pectinesterase inhibitor 28 (PME28), Pectinesterase (AXX17_At5g07090), Probable pectinesterase 53 (PME53), Probable pectinesterase/pectinesterase inhibitor 46 (PME46), Pectinesterase (C24_LOCUS14527), Pectinesterase (C24_LOCUS496), Probable pectinesterase/pectinesterase inhibitor 17 (PME17), Pectinesterase (C24_LOCUS17201), Pectinesterase (AXX17_At2g22270), Pectinesterase (AN1_LOCUS22880), Pectinesterase (C24_LOCUS8124), Pectinesterase (AN1_LOCUS10123), Probable pectinesterase/pectinesterase inhibitor 61 (PME61), Probable pectinesterase 66 (PME66), Pectinesterase (AN1_LOCUS9036), Pectinesterase (C24_LOCUS4397), Pectinesterase (AN1_LOCUS12796), Pectinesterase (AXX17_At2g42790), Pectinesterase (C24_LOCUS23295), Pectinesterase (AN1_LOCUS12795), Pectinesterase (AT9943_LOCUS10326), Pectinesterase (At5g47500), Pectinesterase (AN1_LOCUS22688), Pectinesterase (AT9943_LOCUS12556), Probable pectinesterase/pectinesterase inhibitor 6 (PME6), Pectinesterase (AT9943_LOCUS390), Probable pectinesterase 48 (PME48), Pectinesterase (AXX17_At1g64100), Probable pectinesterase 49 (PME49), Pectinesterase (AT9943_LOCUS22257), Probable pectinesterase 50 (PME50), Pectinesterase (AXX17_At3g17940), Pectinesterase (AT9943_LOCUS11013), Pectinesterase (AT9943_LOCUS7745), Pectinesterase, Probable pectinesterase/pectinesterase inhibitor 19 (PME19), Pectinesterase (AXX17_At2g45050), Probable pectinesterase/pectinesterase inhibitor 40 (PME40), Pectinesterase (AXX17_At1g11920), Pectinesterase (AT9943_LOCUS163), Pectinesterase (AN1_LOCUS6030), Pectinesterase (AXX17_At3g30550), Pectinesterase (AN1_LOCUS17021), Pectinesterase (AXX17_At3g14890), Pectinesterase (AN1_LOCUS17024), Pectinesterase (C24_LOCUS21457), Pectinesterase (AT9943_LOCUS7323), Pectinesterase (AN1_LOCUS11259), Probable pectinesterase/pectinesterase inhibitor 39 (PME39), Pectinesterase (AXX17_At2g44790), Pectinesterase (AT9943_LOCUS21897), Pectinesterase (AT9943_LOCUS12968), Pectinesterase (AT9943_LOCUS10651), Pectinesterase (PE11), Pectinesterase (AT9943_LOCUS11014), Pectinesterase (AN1_LOCUS11234), Pectinesterase (At2g19150), Pectinesterase (AT9943_LOCUS9709), Pectinesterase (AN1_LOCUS26477), Pectinesterase (AN1_LOCUS2467), Pectinesterase (AXX17_At5g19650), Putative pectinesterase/pectinesterase inhibitor 43 (PME43), Pectinesterase (AXX17_At3g31890), Pectinesterase (AXX17_At4g02900), Probable pectinesterase/pectinesterase inhibitor 34 (PME34), Pectinesterase 1 (PME1), Pectinesterase (AT9943_LOCUS18736), Pectinesterase (AT9943_LOCUS2030), Putative pectinesterase 63 (PME63), Pectinesterase (AN1_LOCUS23418), Pectinesterase (AXX17_At3g05180), Pectinesterase (AN1_LOCUS13885), Pectinesterase 2 (PME2), Pectinesterase (AN1_LOCUS4796), Pectinesterase (AN1_LOCUS21563), Pectinesterase (AT9943_LOCUS7106), Probable pectinesterase/pectinesterase inhibitor 21 (PME21), Pectinesterase (AXX17_At2g22280), Pectinesterase (AXX17_At1g51200), Putative pectinesterase/pectinesterase inhibitor 45 (PME45), Pectinesterase (AN1_LOCUS21561), Pectinesterase (C24_LOCUS4029), Pectinesterase (AXX17_At4g02930), Probable pectinesterase/pectinesterase inhibitor 12 (PME12), Probable pectinesterase/pectinesterase inhibitor 44 (PME44), Pectinesterase, Pectinesterase/pectinesterase inhibitor 3 (PME3), Pectinesterase (AT9943_LOCUS14631), Pectinesterase (AT9943_LOCUS4085), Pectinesterase (AN1_LOCUS10124), Pectinesterase (C24_LOCUS26299), Pectinesterase (C24_LOCUS21456), Pectinesterase (AT9943_LOCUS22793), Pectinesterase (C24_LOCUS21201), Pectinesterase (AXX17_At5g50300), Pectinesterase (AT9943_LOCUS5096), Pectinesterase (AXX17_At1g24390), Pectinesterase (AXX17_At1g11900), Pectinesterase (C24_LOCUS9970), Probable pectinesterase/pectinesterase inhibitor 58 (PME58), Pectinesterase (C24_LOCUS23397), Pectinesterase (AT9943_LOCUS11270), Pectinesterase (C24_LOCUS16892), Putative pectinesterase 57 (PME57), Pectinesterase (PME44), Pectinesterase (AT9943_LOCUS17389), Pectinesterase (C24_LOCUS12627), Pectinesterase (AXX17_At3g10560), Pectinesterase (AXX17_At3g55110), Pectinesterase (AXX17_At3g10570), Pectinesterase (C24_LOCUS26601), Pectinesterase (C24_LOCUS16649), Putative pectinesterase 11 (PME11), Pectinesterase (AT9943_LOCUS9665), Pectinesterase (AN1_LOCUS316), Pectinesterase (AT9943_LOCUS14629), Pectinesterase (AT9943_LOCUS18574), Pectinesterase (AXX17_At1g01970), Pectinesterase (AN1_LOCUS26779), Pectinesterase (AXX17_At5g07110), Pectinesterase (AXX17_At4g06570), Pectinesterase (AXX17_At5g50310), Pectinesterase, Pectinesterase (AT9943_LOCUS7323), Pectinesterase (AT9943_LOCUS10200), Pectinesterase (AXX17_At1g51190), Pectinesterase (AXX17_At2g33420), Pectinesterase (AN1_LOCUS12015), Pectinesterase, Pectinesterase (At4g15980), Pectinesterase (AN1_LOCUS12388), Pectinesterase (C24_LOCUS1169), Pectinesterase (AXX17_At3g05190), Pectinesterase (AXX17_At1g48300), Pectinesterase (AT9943_LOCUS18355), Putative pectinesterase/pectinesterase inhibitor 24 (PME24), Pectinesterase (C24_LOCUS1145), Putative pectinesterase/pectinesterase inhibitor 26 (PME26), Pectinesterase (AN1_LOCUS1256), Pectinesterase (AT9943_LOCUS4084), Probable pectinesterase/pectinesterase inhibitor 35 (PME35), Pectinesterase (AT9943_LOCUS14153), Pectinesterase (AT9943_LOCUS23058), Pectinesterase (AXX17_At5g04420), Pectinesterase (AT9943_LOCUS9684), Pectinesterase (AXX17_At2g44780), Pectinesterase (AT9943_LOCUS15743), Pectinesterase (AXX17_At4g00230), Pectinesterase (C24_LOCUS8889), Pectinesterase (AN1_LOCUS11865), Pectinesterase (At5g09760), Pectinesterase (AT9943_LOCUS21545), Pectinesterase (AN1_LOCUS1233), Pectinesterase (C24_LOCUS16162), Pectinesterase (AN1_LOCUS3781), Pectinesterase (AXX17_At5g09310), Pectinesterase (AXX17_At5g20800), Pectinesterase (AT9943_LOCUS21896), Pectinesterase (AT9943_LOCUS20164), Pectinesterase (AT9943_LOCUS9666), Pectinesterase (AT9943_LOCUS14282), Pectinesterase (AXX17_At1g04730), Probable pectinesterase/pectinesterase inhibitor 41 (PME41), Pectinesterase (AXX17_At1g11660), Pectinesterase (At5g26810), Pectinesterase (AT9943_LOCUS18355), Pectinesterase (C24_LOCUS25226), Pectinesterase (AT9943_LOCUS19528), Pectinesterase (AT9943_LOCUS18572), Pectinesterase (AT9943_LOCUS14422), Pectinesterase (AN1_LOCUS11866)
  2. Pectate lyase (T26I12.20), Pectate lyase (AT9943_LOCUS4893), Pectate lyase (AXX17_At5g62760), Pectate lyase (AXX17_At3g47590), Pectate lyase (AXX17_At3g26720), Pectate lyase (AT9943_LOCUS2541), Probable pectate lyase 7 (At3g01270), Pectate lyase (AN1_LOCUS1298), Pectate lyase (AXX17_At4g14900), Pectate lyase (AN1_LOCUS25848), Pectate lyase (AT9943_LOCUS18299), Pectate lyase (AN1_LOCUS18923), Probable pectate lyase 18 (At4g24780), Pectate lyase (At3g27400), Pectate lyase (AXX17_At3g49450), Probable pectate lyase 16 (At4g22080), Putative pectate lyase 17 (At4g22090), Pectate lyase (AT9943_LOCUS15451), Pectate lyase (AN1_LOCUS17926), Pectate lyase (AXX17_At4g25600), Pectate lyase (AXX17_At3g09180), Pectate lyase (AN1_LOCUS26633), Putative pectate lyase 14 (At4g13210), Pectate lyase (C24_LOCUS18820), Pectate lyase (C24_LOCUS13733), Pectate lyase (AXX17_At1g61710), Pectate lyase (At3g55140), Probable pectate lyase 20 (At5g48900), Pectate lyase (At5g48900), Pectate lyase (AXX17_At3g06910), Probable pectate lyase 6 (At2g02720), Pectate lyase (AXX17_At5g54880), Pectate lyase (AN1_LOCUS14239), Pectate lyase (At1g14420), Pectate lyase (AXX17_At4g15660), Pectate lyase (At3g01270), Pectate lyase (At5g04310), Pectate lyase (AN1_LOCUS13896), Pectate lyase, Pectate lyase (AT9943_LOCUS11967), Pectate lyase (At3g09540), Pectate lyase (At5g09280), Probable pectate lyase 22 (At5g63180), Pectate lyase (C24_LOCUS12085), Pectate lyase (AXX17_At3g00310), Pectate lyase (AT9943_LOCUS10532), Pectate lyase (AXX17_At1g04020), Pectate lyase (At3g01270), Pectate lyase (AN1_LOCUS25134), Pectate lyase (At3g55140), Pectate lyase (AXX17_At4g28670), Pectate lyase (C24_LOCUS24965), Pectate lyase (C24_LOCUS1210), Pectate lyase (AN1_LOCUS15686), Putative pectate lyase 2 (At1g11920), Pectate lyase (At3g07010), Pectate lyase, Pectate lyase (C24_LOCUS15770), Probable pectate lyase 8 (At3g07010), Probable pectate lyase 4 (At1g30350), Pectate lyase (AT9943_LOCUS13653), Pectate lyase (C24_LOCUS17875), Pectate lyase (AXX17_At1g30780), Pectate lyase (C24_LOCUS11215), Probable pectate lyase 19 (At5g15110), Pectate lyase (AN1_LOCUS15886), Pectate lyase (F11F8_12), Pectate lyase (AT9943_LOCUS16316), Probable pectate lyase 13 (PMR6), Pectate lyase (AXX17_At2g01680), Pectate lyase (At3g24230), Probable pectate lyase 3 (AT59), Pectate lyase (C24_LOCUS21132), Probable pectate lyase 5 (At1g67750), Putative pectate lyase 21 (At5g55720), Pectate lyase (At4g13210), Pectate lyase (C24_LOCUS5678), Probable pectate lyase 12 (At3g53190), Pectate lyase, Pectate lyase (AN1_LOCUS5787), Pectate lyase (At5g04310), Pectate lyase (AT9943_LOCUS15500), Pectate lyase (AT9943_LOCUS13674), Pectate lyase (AN1_LOCUS12252), Pectate lyase (AXX17_At5g03700), Pectate lyase (AT9943_LOCUS12200), Pectate lyase (At4g13710), Pectate lyase (AXX17_At3g49720), Pectate lyase (AT9943_LOCUS19182), Pectate lyase (AXX17_At4g25610), Pectate lyase (C24_LOCUS19119), Probable pectate lyase 15 (At4g13710), Pectate lyase (At3g53190), Pectate lyase, Pectate lyase (AXX17_At1g15010), Putative pectate lyase 11 (At3g27400), Pectate lyase (At5g04310), Pectate lyase (C24_LOCUS11867), Pectate lyase (At3g07010), Pectate lyase (AN1_LOCUS17988), Pectate lyase (AT9943_LOCUS22928), Pectate lyase (AT9943_LOCUS22269), Pectate lyase (AT9943_LOCUS9790), Pectate lyase (AT9943_LOCUS1238), Pectate lyase (AT9943_LOCUS16576), Pectate lyase (At1g11920), Probable pectate lyase 9 (At3g24230), Pectate lyase (AXX17_At3g29900), Probable pectate lyase 1 (At1g04680), Pectate lyase (At3g07010), Pectate lyase (AN1_LOCUS21236), Pectate lyase (AT9943_LOCUS11923), Pectate lyase (AXX17_At5g14600), Pectate lyase (AN1_LOCUS1561), Pectate lyase (AXX17_At5g08800), Probable pectate lyase 10 (At3g24670), Pectate lyase (AN1_LOCUS15863), Pectate lyase (C24_LOCUS22171)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei315Substrate; for pectinesterase activityBy similarity1
Binding sitei345Substrate; for pectinesterase activityBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei367Transition state stabilizerBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei368Proton donor; for pectinesterase activityPROSITE-ProRule annotation1
Active sitei389Nucleophile; for pectinesterase activityPROSITE-ProRule annotation1
Binding sitei448Substrate; for pectinesterase activityBy similarity1
Binding sitei450Substrate; for pectinesterase activityBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAspartyl esterase, Hydrolase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT3G05620-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00545;UER00823

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative pectinesterase/pectinesterase inhibitor 22
Including the following 2 domains:
Pectinesterase inhibitor 22
Alternative name(s):
Pectin methylesterase inhibitor 22
Pectinesterase 22 (EC:3.1.1.11)
Short name:
PE 22
Alternative name(s):
Pectin methylesterase 22
Short name:
AtPME22
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PME22
Synonyms:ARATH22
Ordered Locus Names:At3g05620
ORF Names:F18C1.11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G05620

The Arabidopsis Information Resource

More...
TAIRi
locus:2078047, AT3G05620

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell wall, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000037167820 – 543Putative pectinesterase/pectinesterase inhibitor 22Add BLAST524

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi211N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi263N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi382 ↔ 402By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9M9W7

PRoteomics IDEntifications database

More...
PRIDEi
Q9M9W7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
234680

PTM databases

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
Q9M9W7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9M9W7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9M9W7, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT3G05620.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9M9W7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni38 – 197Pectinesterase inhibitor 22Add BLAST160
Regioni240 – 527Pectinesterase 22Add BLAST288

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi131 – 134Poly-Gly4
Compositional biasi144 – 147Poly-Ala4
Compositional biasi285 – 288Poly-Lys4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the PMEI family.Curated
In the C-terminal section; belongs to the pectinesterase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QU1M, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012243_9_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9M9W7

Identification of Orthologs from Complete Genome Data

More...
OMAi
WSMLEMN

Database of Orthologous Groups

More...
OrthoDBi
674407at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9M9W7

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.140.40, 1 hit
2.160.20.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035513, Invertase/methylesterase_inhib
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR033131, Pectinesterase_Asp_AS
IPR000070, Pectinesterase_cat
IPR006501, Pectinesterase_inhib_dom
IPR018040, Pectinesterase_Tyr_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01095, Pectinesterase, 1 hit
PF04043, PMEI, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00856, PMEI, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101148, SSF101148, 1 hit
SSF51126, SSF51126, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01614, PME_inhib, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00800, PECTINESTERASE_1, 1 hit
PS00503, PECTINESTERASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9M9W7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGITTALLLV MLMSVHTSSY ETTILKPYKE DNFRSLVAKA CQFIDAHELC
60 70 80 90 100
VSNIWTHVKE SGHGLNPHSV LRAAVKEAHD KAKLAMERIP TVMMLSIRSR
110 120 130 140 150
EQVAIEDCKE LVGFSVTELA WSMLEMNKLH GGGGIDLDDG SHDAAAAGGN
160 170 180 190 200
LKTWLSAAMS NQDTCLEGFE GTERKYEELI KGSLRQVTQL VSNVLDMYTQ
210 220 230 240 250
LNALPFKASR NESVIASPEW LTETDESLMM RHDPSVMHPN TVVAIDGKGK
260 270 280 290 300
YRTINEAINE APNHSTKRYV IYVKKGVYKE NIDLKKKKTN IMLVGDGIGQ
310 320 330 340 350
TIITGDRNFM QGLTTFRTAT VAVSGRGFIA KDITFRNTAG PQNRQAVALR
360 370 380 390 400
VDSDQSAFYR CSVEGYQDTL YAHSLRQFYR DCEIYGTIDF IFGNGAAVLQ
410 420 430 440 450
NCKIYTRVPL PLQKVTITAQ GRKSPNQNTG FVIQNSYVLA TQPTYLGRPW
460 470 480 490 500
KLYSRTVYMN TYMSQLVQPR GWLEWFGNFA LDTLWYGEYN NIGPGWRSSG
510 520 530 540
RVKWPGYHIM DKRTALSFTV GSFIDGRRWL PATGVTFTAG LAN
Length:543
Mass (Da):60,806
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i012165468B4C084F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC011620 Genomic DNA Translation: AAF26135.1
CP002686 Genomic DNA Translation: AEE74267.1

NCBI Reference Sequences

More...
RefSeqi
NP_187213.1, NM_111435.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G05620.1; AT3G05620.1; AT3G05620

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
819728

Gramene; a comparative resource for plants

More...
Gramenei
AT3G05620.1; AT3G05620.1; AT3G05620

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G05620

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011620 Genomic DNA Translation: AAF26135.1
CP002686 Genomic DNA Translation: AEE74267.1
RefSeqiNP_187213.1, NM_111435.2

3D structure databases

SMRiQ9M9W7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G05620.1

PTM databases

MetOSiteiQ9M9W7

Proteomic databases

PaxDbiQ9M9W7
PRIDEiQ9M9W7
ProteomicsDBi234680

Genome annotation databases

EnsemblPlantsiAT3G05620.1; AT3G05620.1; AT3G05620
GeneIDi819728
GrameneiAT3G05620.1; AT3G05620.1; AT3G05620
KEGGiath:AT3G05620

Organism-specific databases

AraportiAT3G05620
TAIRilocus:2078047, AT3G05620

Phylogenomic databases

eggNOGiENOG502QU1M, Eukaryota
HOGENOMiCLU_012243_9_1_1
InParanoidiQ9M9W7
OMAiWSMLEMN
OrthoDBi674407at2759
PhylomeDBiQ9M9W7

Enzyme and pathway databases

UniPathwayiUPA00545;UER00823
BioCyciARA:AT3G05620-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9M9W7

Gene expression databases

ExpressionAtlasiQ9M9W7, baseline and differential
GenevisibleiQ9M9W7, AT

Family and domain databases

Gene3Di1.20.140.40, 1 hit
2.160.20.10, 1 hit
InterProiView protein in InterPro
IPR035513, Invertase/methylesterase_inhib
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR033131, Pectinesterase_Asp_AS
IPR000070, Pectinesterase_cat
IPR006501, Pectinesterase_inhib_dom
IPR018040, Pectinesterase_Tyr_AS
PfamiView protein in Pfam
PF01095, Pectinesterase, 1 hit
PF04043, PMEI, 1 hit
SMARTiView protein in SMART
SM00856, PMEI, 1 hit
SUPFAMiSSF101148, SSF101148, 1 hit
SSF51126, SSF51126, 1 hit
TIGRFAMsiTIGR01614, PME_inhib, 1 hit
PROSITEiView protein in PROSITE
PS00800, PECTINESTERASE_1, 1 hit
PS00503, PECTINESTERASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPME22_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9M9W7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: October 1, 2000
Last modified: December 2, 2020
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again