UniProtKB - Q9M2N5 (DSLE_ARATH)
Protein
Zinc finger BED domain-containing protein DAYSLEEPER
Gene
HAT
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transposase-like protein that is essential for plant growth and development. Binds the promoter region of the DNA helicase KU70 and genes involved in chromatin remodeling. May regulate global gene expression by recruiting other cellular factors.2 Publications
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 65 – 132 | BED-typePROSITE-ProRule annotationAdd BLAST | 68 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- protein dimerization activity Source: InterPro
GO - Biological processi
- post-embryonic development Source: TAIR
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger BED domain-containing protein DAYSLEEPERAlternative name(s): Transposase-like protein DAYSLEEPER |
Gene namesi | Name:HAT Ordered Locus Names:At3g42170 ORF Names:T27B3.40 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT3G42170 |
TAIRi | locus:2100809, AT3G42170 |
Pathology & Biotechi
Disruption phenotypei
Very slow growth and absence of expansion of cotyledons or development of normal leaves or floral organs. Short root with an excess of abnormal root hairs. Extremely rare production of some photosynthetic tissue.2 Publications
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 70 | V → A: Loss of DNA-binding capacity. 1 Publication | 1 | |
Mutagenesisi | 73 | H → A: Loss of DNA-binding capacity. 1 Publication | 1 | |
Mutagenesisi | 88 | C → A: Loss of DNA-binding capacity. 1 Publication | 1 | |
Mutagenesisi | 91 | C → A: Loss of DNA-binding capacity. 1 Publication | 1 | |
Mutagenesisi | 109 | L → A: Loss of DNA-binding capacity. 1 Publication | 1 | |
Mutagenesisi | 112 | H → A: Loss of DNA-binding capacity. 1 Publication | 1 | |
Mutagenesisi | 118 | C → A: Loss of DNA-binding capacity. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000429561 | 1 – 696 | Zinc finger BED domain-containing protein DAYSLEEPERAdd BLAST | 696 |
Proteomic databases
PaxDbi | Q9M2N5 |
PRIDEi | Q9M2N5 |
ProteomicsDBi | 224294 |
PTM databases
iPTMneti | Q9M2N5 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9M2N5, baseline and differential |
Genevisiblei | Q9M2N5, AT |
Interactioni
Subunit structurei
Homodimer.
1 PublicationGO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
BioGRIDi | 529778, 3 interactors |
STRINGi | 3702.AT3G42170.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 592 – 674 | HATC (Hobo-Ac-Tam3) domainAdd BLAST | 83 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 65 – 132 | BED-typePROSITE-ProRule annotationAdd BLAST | 68 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | KOG1121, Eukaryota |
HOGENOMi | CLU_009123_1_2_1 |
InParanoidi | Q9M2N5 |
OrthoDBi | 223749at2759 |
PhylomeDBi | Q9M2N5 |
Family and domain databases
InterProi | View protein in InterPro IPR025525, hAT-like_transposase_RNase-H IPR008906, HATC_C_dom IPR012337, RNaseH-like_sf IPR003656, Znf_BED IPR036236, Znf_C2H2_sf |
Pfami | View protein in Pfam PF05699, Dimer_Tnp_hAT, 1 hit PF14372, DUF4413, 1 hit |
SUPFAMi | SSF53098, SSF53098, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50808, ZF_BED, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9M2N5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEVYNDDTEM RSPETQPIKE TALEVYNDTA EIRSPETQPI EETALEVYND
60 70 80 90 100
TEMVSPETQP IKRRKKKSMV WEHFTIEAVE PNCRRAFCKG CNQSFAYSNG
110 120 130 140 150
NKVAGTSHLK RHIFKGTCPA LIHTHDNDNN PLMSTPYTPK TDTPRRRYRS
160 170 180 190 200
QNNASPYVAF NQDKCRQEIA KMIIMHDYPL HMVQHPGFVS FVQSIQPHFD
210 220 230 240 250
AVSFNNVQGD CVATYLAEKQ NVMKSLEGIP GRFCLTLDFW TSKLTLGYVF
260 270 280 290 300
ITAHYIDSDW KIQKKLLNVL MESYPEADEA LSLAVANCVS EWGLEGKLFN
310 320 330 340 350
VTFNHPASNS AVENIRPQLC IKNPGILDGQ LVIGNCVART FGSLAKDVLE
360 370 380 390 400
KGKDVIKNIR DSVKHVKTSE SHEERFTELK EQLQVPSEKV LSLDDQTQWN
410 420 430 440 450
TTYMMLVAAS ELKEVFSCLD TADPDYKKPP SAEDWRHVEA LCTFLKPLFE
460 470 480 490 500
AVSTLQSTGN PSAVTFFHEV WKTQSDLSRA IAGEDPFVTG IAKTMQEKVD
510 520 530 540 550
KYWRDCSLVL AMAVVMDPRF KMKLVEFSFS KIFGEDAGKN IKTVDDGIHE
560 570 580 590 600
LFTEYMALPS PQNTTSEGGK ADGLSDFDTY IMETTGQNLK SELDQYLDET
610 620 630 640 650
LLPRVQEFDV LDWWKQNKLK YPTLSKMARD ILSIPVSAAA FDYVFDMEPR
660 670 680 690
EMDEYKTSLR PETVEALICA REWLLESNAS SSAAAQNASA TIKSEA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1I9LLZ3 | A0A1I9LLZ3_ARATH | BED zinc finger and hAT dimerizatio... | DAYSLEEPER At3g42170 | 674 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 338 | A → G in AAW28145 (PubMed:16015335).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY728267 mRNA Translation: AAW28145.1 AL137079 Genomic DNA Translation: CAB68118.1 CP002686 Genomic DNA Translation: AEE77728.1 BT003157 mRNA Translation: AAO24589.1 AK227645 mRNA Translation: BAE99632.1 |
PIRi | T46111 |
RefSeqi | NP_189803.1, NM_114084.3 |
Genome annotation databases
EnsemblPlantsi | AT3G42170.1; AT3G42170.1; AT3G42170 |
GeneIDi | 3769417 |
Gramenei | AT3G42170.1; AT3G42170.1; AT3G42170 |
KEGGi | ath:AT3G42170 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY728267 mRNA Translation: AAW28145.1 AL137079 Genomic DNA Translation: CAB68118.1 CP002686 Genomic DNA Translation: AEE77728.1 BT003157 mRNA Translation: AAO24589.1 AK227645 mRNA Translation: BAE99632.1 |
PIRi | T46111 |
RefSeqi | NP_189803.1, NM_114084.3 |
3D structure databases
SMRi | Q9M2N5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 529778, 3 interactors |
STRINGi | 3702.AT3G42170.1 |
PTM databases
iPTMneti | Q9M2N5 |
Proteomic databases
PaxDbi | Q9M2N5 |
PRIDEi | Q9M2N5 |
ProteomicsDBi | 224294 |
Genome annotation databases
EnsemblPlantsi | AT3G42170.1; AT3G42170.1; AT3G42170 |
GeneIDi | 3769417 |
Gramenei | AT3G42170.1; AT3G42170.1; AT3G42170 |
KEGGi | ath:AT3G42170 |
Organism-specific databases
Araporti | AT3G42170 |
TAIRi | locus:2100809, AT3G42170 |
Phylogenomic databases
eggNOGi | KOG1121, Eukaryota |
HOGENOMi | CLU_009123_1_2_1 |
InParanoidi | Q9M2N5 |
OrthoDBi | 223749at2759 |
PhylomeDBi | Q9M2N5 |
Miscellaneous databases
PROi | PR:Q9M2N5 |
Gene expression databases
ExpressionAtlasi | Q9M2N5, baseline and differential |
Genevisiblei | Q9M2N5, AT |
Family and domain databases
InterProi | View protein in InterPro IPR025525, hAT-like_transposase_RNase-H IPR008906, HATC_C_dom IPR012337, RNaseH-like_sf IPR003656, Znf_BED IPR036236, Znf_C2H2_sf |
Pfami | View protein in Pfam PF05699, Dimer_Tnp_hAT, 1 hit PF14372, DUF4413, 1 hit |
SUPFAMi | SSF53098, SSF53098, 1 hit SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS50808, ZF_BED, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DSLE_ARATH | |
Accessioni | Q9M2N5Primary (citable) accession number: Q9M2N5 Secondary accession number(s): Q5IH79 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 9, 2014 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names