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Entry version 130 (05 Jun 2019)
Sequence version 1 (01 Oct 2000)
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Protein
Submitted name:

Tetratricopeptide repeat (TPR)-like superfamily protein

Gene

T20K12.70

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • RNA modification Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Tetratricopeptide repeat (TPR)-like superfamily proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:T20K12.70Imported
Ordered Locus Names:At3g61170Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT3G61170

The Arabidopsis Information Resource

More...
TAIRi
locus:2098901 AT3G61170

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9M2E7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati27 – 57PPRPROSITE-ProRule annotationAdd BLAST31
Repeati58 – 88PPRPROSITE-ProRule annotationAdd BLAST31
Repeati89 – 123PPRPROSITE-ProRule annotationAdd BLAST35
Repeati124 – 158PPRPROSITE-ProRule annotationAdd BLAST35
Repeati159 – 189PPRPROSITE-ProRule annotationAdd BLAST31
Repeati191 – 225PPRPROSITE-ProRule annotationAdd BLAST35
Repeati226 – 260PPRPROSITE-ProRule annotationAdd BLAST35
Repeati261 – 291PPRPROSITE-ProRule annotationAdd BLAST31
Repeati292 – 326PPRPROSITE-ProRule annotationAdd BLAST35
Repeati363 – 393PPRPROSITE-ProRule annotationAdd BLAST31
Repeati394 – 428PPRPROSITE-ProRule annotationAdd BLAST35
Repeati464 – 494PPRPROSITE-ProRule annotationAdd BLAST31
Repeati495 – 525PPRPROSITE-ProRule annotationAdd BLAST31
Repeati531 – 561PPRPROSITE-ProRule annotationAdd BLAST31
Repeati563 – 593PPRPROSITE-ProRule annotationAdd BLAST31
Repeati597 – 631PPRPROSITE-ProRule annotationAdd BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini633 – 737DYW_deaminaseInterPro annotationAdd BLAST105

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PPR family. PCMP-H subfamily.SAAS annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4197 Eukaryota
ENOG410Z7Z7 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000237570

Identification of Orthologs from Complete Genome Data

More...
OMAi
RAATNLF

Database of Orthologous Groups

More...
OrthoDBi
1344243at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032867 DYW_dom
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 9 hits
PF13041 PPR_2, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00756 PPR, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51375 PPR, 16 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9M2E7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHRLNYRKWR LPLKPFGSCI HSYADRTKLH SNLLLGDLSK SGRVDEARQM
60 70 80 90 100
FDKMPERDEF TWNTMIVAYS NSRRLSDAEK LFRSNPVKNT ISWNALISGY
110 120 130 140 150
CKSGSKVEAF NLFWEMQSDG IKPNEYTLGS VLRMCTSLVL LLRGEQIHGH
160 170 180 190 200
TIKTGFDLDV NVVNGLLAMY AQCKRISEAE YLFETMEGEK NNVTWTSMLT
210 220 230 240 250
GYSQNGFAFK AIECFRDLRR EGNQSNQYTF PSVLTACASV SACRVGVQVH
260 270 280 290 300
CCIVKSGFKT NIYVQSALID MYAKCREMES ARALLEGMEV DDVVSWNSMI
310 320 330 340 350
VGCVRQGLIG EALSMFGRMH ERDMKIDDFT IPSILNCFAL SRTEMKIASS
360 370 380 390 400
AHCLIVKTGY ATYKLVNNAL VDMYAKRGIM DSALKVFEGM IEKDVISWTA
410 420 430 440 450
LVTGNTHNGS YDEALKLFCN MRVGGITPDK IVTASVLSAS AELTLLEFGQ
460 470 480 490 500
QVHGNYIKSG FPSSLSVNNS LVTMYTKCGS LEDANVIFNS MEIRDLITWT
510 520 530 540 550
CLIVGYAKNG LLEDAQRYFD SMRTVYGITP GPEHYACMID LFGRSGDFVK
560 570 580 590 600
VEQLLHQMEV EPDATVWKAI LAASRKHGNI ENGERAAKTL MELEPNNAVP
610 620 630 640 650
YVQLSNMYSA AGRQDEAANV RRLMKSRNIS KEPGCSWVEE KGKVHSFMSE
660 670 680 690 700
DRRHPRMVEI YSKVDEMMLL IKEAGYFADM SFALHDLDKE GKELGLAYHS
710 720 730 740 750
EKLAVAFGLL VVPSGAPIRI IKNLRVCGDC HSAMKLLVTF AIEGKLGKFC
760 770 780
ISVCNNESYK VTNLQLYTFK LLVDVVAEVS EGS
Length:783
Mass (Da):87,739
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2DB830058087BA00
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP002686 Genomic DNA Translation: AEE80164.1
AL137898 Genomic DNA Translation: CAB71047.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T47909

NCBI Reference Sequences

More...
RefSeqi
NP_191676.1, NM_115981.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G61170.1; AT3G61170.1; AT3G61170

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
825289

Gramene; a comparative resource for plants

More...
Gramenei
AT3G61170.1; AT3G61170.1; AT3G61170

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G61170

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002686 Genomic DNA Translation: AEE80164.1
AL137898 Genomic DNA Translation: CAB71047.1
PIRiT47909
RefSeqiNP_191676.1, NM_115981.2

3D structure databases

SMRiQ9M2E7
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G61170.1; AT3G61170.1; AT3G61170
GeneIDi825289
GrameneiAT3G61170.1; AT3G61170.1; AT3G61170
KEGGiath:AT3G61170

Organism-specific databases

AraportiAT3G61170
TAIRilocus:2098901 AT3G61170

Phylogenomic databases

eggNOGiKOG4197 Eukaryota
ENOG410Z7Z7 LUCA
HOGENOMiHOG000237570
OMAiRAATNLF
OrthoDBi1344243at2759

Family and domain databases

Gene3Di1.25.40.10, 4 hits
InterProiView protein in InterPro
IPR032867 DYW_dom
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 9 hits
PF13041 PPR_2, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
TIGRFAMsiTIGR00756 PPR, 8 hits
PROSITEiView protein in PROSITE
PS51375 PPR, 16 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9M2E7_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9M2E7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: June 5, 2019
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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