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Entry version 160 (16 Oct 2019)
Sequence version 1 (01 Oct 2000)
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Protein
Submitted name:

RNA binding (RRM/RBD/RNP motifs) family protein

Gene

F9K21.210

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RNA binding (RRM/RBD/RNP motifs) family proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:F9K21.210Imported
Ordered Locus Names:At3g45630Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G45630

The Arabidopsis Information Resource

More...
TAIRi
locus:2085617 AT3G45630

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9M1E4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9M1E4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9M1E4 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q9M1E4, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT3G45630.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9M1E4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 57RING-typeInterPro annotationAdd BLAST49
Domaini109 – 195RRMInterPro annotationAdd BLAST87

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni77 – 99DisorderedSequence analysisAdd BLAST23
Regioni242 – 299DisorderedSequence analysisAdd BLAST58
Regioni341 – 406DisorderedSequence analysisAdd BLAST66
Regioni763 – 787DisorderedSequence analysisAdd BLAST25
Regioni883 – 920DisorderedSequence analysisAdd BLAST38
Regioni966 – 989DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi77 – 97PolyampholyteSequence analysisAdd BLAST21
Compositional biasi260 – 299PolarSequence analysisAdd BLAST40
Compositional biasi341 – 362PolarSequence analysisAdd BLAST22
Compositional biasi388 – 406PolarSequence analysisAdd BLAST19

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2068 Eukaryota
COG5175 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000085071

KEGG Orthology (KO)

More...
KOi
K10643

Identification of Orthologs from Complete Genome Data

More...
OMAi
VIRNAYH

Database of Orthologous Groups

More...
OrthoDBi
103300at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd16618 mRING-HC-C4C4_CNOT4, 1 hit
cd12438 RRM_CNOT4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034261 CNOT4_RRM
IPR039780 Mot2
IPR039515 NOT4_mRING-HC-C4C4
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD

The PANTHER Classification System

More...
PANTHERi
PTHR12603 PTHR12603, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00361 RRM_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 1 hit
PS50089 ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9M1E4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDYGEKTCP LCAEEMDLTD QQLKPCKCGY QICVWCWHHI MDMAEKDQSE
60 70 80 90 100
GRCPACRTPY DKEKIVGMTV DQERLASEGN MDRKKIQKSK PKSSDGRKPL
110 120 130 140 150
TSVRVVQRNL VYIVGLPLNL ADEDLLQRKE YFGQYGKVLK VSMSRTATGL
160 170 180 190 200
IQQFPNNTCS VYITYGKEEE AIRCIQSVHG FILDGKALKA CFGTTKYCHA
210 220 230 240 250
WLRNVACNNQ DCLYLHEVGS QEDSFTKDEI ISAHTRVQQI TGATNTMQYR
260 270 280 290 300
SGSMLPPPLD AYTSDSSTGN PIAKVPSSTS VSAPKSSPPS GSSGKSTALP
310 320 330 340 350
AAASWGARLT NQHSLATSAL SNGSLDNQRS TSENGTLATS TVVTKAANGP
360 370 380 390 400
VSSSNSLQKA PLKEEIQSLA EKSKPGVLKP LQQKIVLDPE SKRTTSPNRD
410 420 430 440 450
PSSNQISCLV ESSYNSRVID KPSAVENSLE HTSEIAEDVF DVGKLSADVA
460 470 480 490 500
WMGITTNSRD ETPGVPVVIG THCDLGSITQ SDNDVQNLEQ CRKQSPTNTY
510 520 530 540 550
AEADISLNGI HGSRPEWDWR SGLQSQIDVK EPLEVNDFSS FNNNRRGIAE
560 570 580 590 600
AVSHSTSKFS SSISILDSNH LASRSFQNRE TSCGMDSKTG SSFEIGSDRL
610 620 630 640 650
HLPNGFSEKA MSNMEHSLFA NEGRSNIQNT EDDIISNILD FDPWDESLTS
660 670 680 690 700
QHNFAKLLGQ SDHRASTLES SNLLKQHNDQ SRFSFARHEE SNSQAYDNRS
710 720 730 740 750
YSIYGQLSRD QPLQEFGANR DMYQDKLGSQ NGFASNYSGG YEQFATSPGL
760 770 780 790 800
SSYKSPVART QVSAPPGFSA PNRLPPPGFS SHQRGDLSSD IASGTRLLDS
810 820 830 840 850
ANLLRNAYHV PPPSGNLNAA GDIEFIDPAI LAVGRGRLHN GMETADFDLR
860 870 880 890 900
SGFSSQLNSF DNDARLQLLA QRSLAAQQVN GFHDPRNVNN FSSSFSDPYG
910 920 930 940 950
ISSRPTDQTQ GTGLSPFTQL PRQASANPLL SNGHWDNKWN EPQSGNNLGI
960 970 980
TQLLRNERMG FNDNVYSGFE EPKFRRPGPG DPYNRTYGI
Length:989
Mass (Da):108,438
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i370307DB95E8EE4D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP002686 Genomic DNA Translation: AEE78053.1
CP002686 Genomic DNA Translation: ANM65627.1
AL138657 Genomic DNA Translation: CAB75492.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T47503

NCBI Reference Sequences

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RefSeqi
NP_001327582.1, NM_001339212.1
NP_190149.1, NM_114432.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G45630.1; AT3G45630.1; AT3G45630
AT3G45630.2; AT3G45630.2; AT3G45630

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
823705

Gramene; a comparative resource for plants

More...
Gramenei
AT3G45630.1; AT3G45630.1; AT3G45630
AT3G45630.2; AT3G45630.2; AT3G45630

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G45630

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002686 Genomic DNA Translation: AEE78053.1
CP002686 Genomic DNA Translation: ANM65627.1
AL138657 Genomic DNA Translation: CAB75492.1
PIRiT47503
RefSeqiNP_001327582.1, NM_001339212.1
NP_190149.1, NM_114432.3

3D structure databases

SMRiQ9M1E4
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9M1E4, 2 interactors
STRINGi3702.AT3G45630.1

PTM databases

iPTMnetiQ9M1E4

Proteomic databases

PRIDEiQ9M1E4

Genome annotation databases

EnsemblPlantsiAT3G45630.1; AT3G45630.1; AT3G45630
AT3G45630.2; AT3G45630.2; AT3G45630
GeneIDi823705
GrameneiAT3G45630.1; AT3G45630.1; AT3G45630
AT3G45630.2; AT3G45630.2; AT3G45630
KEGGiath:AT3G45630

Organism-specific databases

AraportiAT3G45630
TAIRilocus:2085617 AT3G45630

Phylogenomic databases

eggNOGiKOG2068 Eukaryota
COG5175 LUCA
HOGENOMiHOG000085071
KOiK10643
OMAiVIRNAYH
OrthoDBi103300at2759

Gene expression databases

ExpressionAtlasiQ9M1E4 baseline and differential

Family and domain databases

CDDicd16618 mRING-HC-C4C4_CNOT4, 1 hit
cd12438 RRM_CNOT4, 1 hit
Gene3Di3.30.40.10, 1 hit
3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034261 CNOT4_RRM
IPR039780 Mot2
IPR039515 NOT4_mRING-HC-C4C4
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR12603 PTHR12603, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00361 RRM_1, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
PS50089 ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9M1E4_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9M1E4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: October 16, 2019
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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