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Protein

ATPase 7, plasma membrane-type

Gene

AHA7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The plasma membrane H+ ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H+-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (By similarity).By similarity

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3324-aspartylphosphate intermediateBy similarity1
Metal bindingi588MagnesiumBy similarity1
Metal bindingi592MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processHydrogen ion transport, Ion transport, Transport
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G60330-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATPase 7, plasma membrane-type (EC:3.6.3.6)
Alternative name(s):
Proton pump 7
Gene namesi
Name:AHA7
Ordered Locus Names:At3g60330
ORF Names:F27H5_120
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G60330
TAIRilocus:2081932 AT3G60330

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 64CytoplasmicSequence analysisAdd BLAST64
Transmembranei65 – 84Helical; Name=1Sequence analysisAdd BLAST20
Topological domaini85 – 96ExtracellularSequence analysisAdd BLAST12
Transmembranei97 – 117Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini118 – 246CytoplasmicSequence analysisAdd BLAST129
Transmembranei247 – 267Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini268 – 276ExtracellularSequence analysis9
Transmembranei277 – 294Helical; Name=4Sequence analysisAdd BLAST18
Topological domaini295 – 643CytoplasmicSequence analysisAdd BLAST349
Transmembranei644 – 665Helical; Name=5Sequence analysisAdd BLAST22
Topological domaini666 – 670ExtracellularSequence analysis5
Transmembranei671 – 693Helical; Name=6Sequence analysisAdd BLAST23
Topological domaini694 – 709CytoplasmicSequence analysisAdd BLAST16
Transmembranei710 – 730Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini731 – 764ExtracellularSequence analysisAdd BLAST34
Transmembranei765 – 785Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini786 – 797CytoplasmicSequence analysisAdd BLAST12
Transmembranei798 – 818Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini819 – 826ExtracellularSequence analysis8
Transmembranei827 – 847Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini848 – 961CytoplasmicSequence analysisAdd BLAST114

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000462801 – 961ATPase 7, plasma membrane-typeAdd BLAST961

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei894PhosphothreonineBy similarity1
Modified residuei910PhosphoserineBy similarity1
Modified residuei942PhosphoserineBy similarity1
Modified residuei960PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LY32
PRIDEiQ9LY32

PTM databases

iPTMnetiQ9LY32

Expressioni

Gene expression databases

ExpressionAtlasiQ9LY32 baseline and differential
GenevisibleiQ9LY32 AT

Interactioni

Subunit structurei

Binds to 14-3-3 proteins. The binding is induced by phosphorylation of Thr-960. Binding to 14-3-3 proteins activates the H+-ATPase (By similarity).By similarity

Protein-protein interaction databases

BioGridi10518, 4 interactors
STRINGi3702.AT3G60330.1

Structurei

3D structure databases

ProteinModelPortaliQ9LY32
SMRiQ9LY32
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni959 – 961Interaction with 14-3-3 proteinsBy similarity3

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0205 Eukaryota
COG0474 LUCA
HOGENOMiHOG000160005
InParanoidiQ9LY32
KOiK01535
OMAiFDNLKCT
OrthoDBiEOG093601UL
PhylomeDBiQ9LY32

Family and domain databases

CDDicd02076 P-type_ATPase_H, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006534 P-type_ATPase_IIIA
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00690 Cation_ATPase_N, 1 hit
PRINTSiPR00120 HATPASE
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01647 ATPase-IIIA_H, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LY32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDIEALKAI TTESIDLENV PVEEVFQHLK CTKEGLTSNE VQERLTLFGY
60 70 80 90 100
NKLEEKKESK ILKFLGFMWN PLSWVMEAAA LMAIGLAHGG GKPADYHDFV
110 120 130 140 150
GIVVLLLINS TISFVEENNA GNAAAALMAQ LAPKAKAVRD GKWNEIDAAE
160 170 180 190 200
LVPGDIVSIK LGDIIPADAR LLEGDPLKID QATLTGESLP VTKNPGASVY
210 220 230 240 250
SGSTCKQGEI EAVVIATGVH TFFGKAAHLV DSTTHVGHFQ KVLTAIGNFC
260 270 280 290 300
ICSIAVGMAI EIVVIYGLQK RGYRVGIDNL LVLLIGGIPI AMPTVLSVTM
310 320 330 340 350
AIGAHRLAQQ GAITKRMTAI EEMAGMDVLC SDKTGTLTLN KLSVDKNLIE
360 370 380 390 400
VFKRGIDRDM AVLMAARAAR LENQDAIDTA IVSMLSDPKE ARAGIKELHF
410 420 430 440 450
LPFSPANRRT ALTYLDGEGK MHRVSKGAPE EILDMAHNKL EIKEKVHATI
460 470 480 490 500
DKFAERGLRS LGLAYQEVPD GDVKGEGGPW DFVALLPLFD PPRHDSAQTI
510 520 530 540 550
ERALHLGVSV KMITGDQLAI AKETGRRLGM GTNMYPSSSL LSDNNTEGVS
560 570 580 590 600
VDELIENADG FAGVFPEHKY EIVKRLQSRK HICGMTGDGV NDAPALKKAD
610 620 630 640 650
IGIAVDDATD AARGASDIVL TEPGLSVIIS AVLTSRAIFQ RMKNYTIYAV
660 670 680 690 700
SITIRIVMGF MLLCVFWEFD FPPFMVLVIA ILNDGTIMTI SKDRVKPSPT
710 720 730 740 750
PDCWKLKEIF ATGVVLGAYL AIMTVVFFWA AYETNFFHNI FHVRNFNQHH
760 770 780 790 800
FKMKDKKVAA HLNEQMASAV YLQVSTISQA LIFVTRSRSW SFVERPGFLL
810 820 830 840 850
VIAFLIAQLV ASVISAMANW PFAGIRSIGW GWTGVIWIFN IVTYMLLDPI
860 870 880 890 900
KFLVRYALSG KSWDRMVEGR TALTGKKNFG QEERMAAWAT EKRTQHGLET
910 920 930 940 950
GQKPVYERNS ATELNNMAEE AKRRAEIARM RELQTLKGKV ESAAKLKGYD
960
LEDPNSNNYT I
Length:961
Mass (Da):105,520
Last modified:October 1, 2000 - v1
Checksum:iBF8F9C5BC234A4F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL163852 Genomic DNA Translation: CAB87870.1
CP002686 Genomic DNA Translation: AEE80046.1
CP002686 Genomic DNA Translation: AEE80047.1
PIRiT49228
RefSeqiNP_001190141.1, NM_001203212.1
NP_191592.5, NM_115897.5
UniGeneiAt.54016

Genome annotation databases

EnsemblPlantsiAT3G60330.1; AT3G60330.1; AT3G60330
AT3G60330.2; AT3G60330.2; AT3G60330
GeneIDi825204
GrameneiAT3G60330.1; AT3G60330.1; AT3G60330
AT3G60330.2; AT3G60330.2; AT3G60330
KEGGiath:AT3G60330

Similar proteinsi

Entry informationi

Entry nameiPMA7_ARATH
AccessioniPrimary (citable) accession number: Q9LY32
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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