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Protein

Probable lipid desaturase ADS3.2, chloroplastic

Gene

ADS3.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

ADS3.2 does not contribute to the FAD5 phenotype.1 Publication

Cofactori

Fe2+By similarity

Pathwayi: polyunsaturated fatty acid biosynthesis

This protein is involved in the pathway polyunsaturated fatty acid biosynthesis, which is part of Lipid metabolism.Curated
View all proteins of this organism that are known to be involved in the pathway polyunsaturated fatty acid biosynthesis and in Lipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandIron

Enzyme and pathway databases

BioCyciARA:AT3G15870-MONOMER
ReactomeiR-ATH-75105 Fatty acyl-CoA biosynthesis
UniPathwayi
UPA00658

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lipid desaturase ADS3.2, chloroplastic1 Publication (EC:1.14.19.-Curated)
Gene namesi
Name:ADS3.21 Publication
Ordered Locus Names:At3g15870Imported
ORF Names:MSJ11.26Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G15870
TAIRilocus:2093207 AT3G15870

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei99 – 118HelicalSequence analysisAdd BLAST20
Transmembranei122 – 139HelicalSequence analysisAdd BLAST18
Transmembranei246 – 266HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid

Pathology & Biotechi

Disruption phenotypei

No visible phenotype and wild-type levels of both Hexadeca 7,10,13-trienoic acid (16:3(7Z,10Z,13Z)) and leaf chlorophyll content.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 57ChloroplastSequence analysisAdd BLAST57
ChainiPRO_000000714558 – 361Probable lipid desaturase ADS3.2, chloroplasticAdd BLAST304

Proteomic databases

PaxDbiQ9LVZ3
PRIDEiQ9LVZ3

Expressioni

Gene expression databases

ExpressionAtlasiQ9LVZ3 baseline and differential
GenevisibleiQ9LVZ3 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G15870.1

Structurei

3D structure databases

ProteinModelPortaliQ9LVZ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi140 – 145Histidine box-1Curated6
Motifi177 – 181Histidine box-2Curated5
Motifi309 – 313Histidine box-3Curated5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi77 – 80Poly-Val4

Domaini

The histidine box domains are involved in binding the catalytic metal ions.By similarity

Sequence similaritiesi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1600 Eukaryota
COG1398 LUCA
HOGENOMiHOG000270353
InParanoidiQ9LVZ3
OMAiYFCGGMP
OrthoDBiEOG09360DCM
PhylomeDBiQ9LVZ3

Family and domain databases

CDDicd03505 Delta9-FADS-like, 1 hit
InterProiView protein in InterPro
IPR015876 Acyl-CoA_DS
IPR005804 FA_desaturase_dom
PANTHERiPTHR11351 PTHR11351, 1 hit
PfamiView protein in Pfam
PF00487 FA_desaturase, 1 hit
PRINTSiPR00075 FACDDSATRASE

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LVZ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMSLSTTLKP LSHFSPFVKR HNPKTNNTLF TLDTHNFTNS FWSKRGGSVS
60 70 80 90 100
HRKHTVVAVY EAPDHVESSW RRLLSEVVVV RTKRSFWERS WTSWDVSKLV
110 120 130 140 150
IFVGTHLLSL LAPFYFSWEA FWVFPWLVFI NGICITLSYH RNLSHRSFDL
160 170 180 190 200
PKWLEYLFAY GGVLAFQGDP IEWVSNHRYH HKHCETQRDP HSPTQGFWFS
210 220 230 240 250
HMAWIFDTSS ILENCGGEEN VDDLVRQPFY RFLQRTVLLH MMAYSFLFYF
260 270 280 290 300
CGGMPLLVWG IGITIAVRLH LTFLVNSVCH IWGTRAWNTS DFSKNNWWVA
310 320 330 340 350
ILTLGEGWHN NHHAFEFSAR HGLEWWQLDI TWCLIRFLEA IGLATNVKLP
360
TETQMKGKAL V
Length:361
Mass (Da):42,343
Last modified:October 14, 2008 - v3
Checksum:i712139C6A2C9ADF3
GO

Sequence cautioni

The sequence AAW51921 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAB02317 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY734685 Genomic DNA Translation: AAW51921.1 Sequence problems.
AB017071 Genomic DNA Translation: BAB02317.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE75739.1
RefSeqiNP_188208.4, NM_112457.6
UniGeneiAt.26150
At.66498

Genome annotation databases

EnsemblPlantsiAT3G15870.1; AT3G15870.1; AT3G15870
GeneIDi820830
GrameneiAT3G15870.1; AT3G15870.1; AT3G15870
KEGGiath:AT3G15870

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY734685 Genomic DNA Translation: AAW51921.1 Sequence problems.
AB017071 Genomic DNA Translation: BAB02317.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE75739.1
RefSeqiNP_188208.4, NM_112457.6
UniGeneiAt.26150
At.66498

3D structure databases

ProteinModelPortaliQ9LVZ3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G15870.1

Proteomic databases

PaxDbiQ9LVZ3
PRIDEiQ9LVZ3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G15870.1; AT3G15870.1; AT3G15870
GeneIDi820830
GrameneiAT3G15870.1; AT3G15870.1; AT3G15870
KEGGiath:AT3G15870

Organism-specific databases

AraportiAT3G15870
TAIRilocus:2093207 AT3G15870

Phylogenomic databases

eggNOGiKOG1600 Eukaryota
COG1398 LUCA
HOGENOMiHOG000270353
InParanoidiQ9LVZ3
OMAiYFCGGMP
OrthoDBiEOG09360DCM
PhylomeDBiQ9LVZ3

Enzyme and pathway databases

UniPathwayi
UPA00658

BioCyciARA:AT3G15870-MONOMER
ReactomeiR-ATH-75105 Fatty acyl-CoA biosynthesis

Miscellaneous databases

PROiPR:Q9LVZ3

Gene expression databases

ExpressionAtlasiQ9LVZ3 baseline and differential
GenevisibleiQ9LVZ3 AT

Family and domain databases

CDDicd03505 Delta9-FADS-like, 1 hit
InterProiView protein in InterPro
IPR015876 Acyl-CoA_DS
IPR005804 FA_desaturase_dom
PANTHERiPTHR11351 PTHR11351, 1 hit
PfamiView protein in Pfam
PF00487 FA_desaturase, 1 hit
PRINTSiPR00075 FACDDSATRASE
ProtoNetiSearch...

Entry informationi

Entry nameiADS32_ARATH
AccessioniPrimary (citable) accession number: Q9LVZ3
Secondary accession number(s): Q5IGR4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: October 14, 2008
Last modified: November 7, 2018
This is version 113 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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Main funding by: National Institutes of Health

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