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Protein

Transcription factor MYB118

Gene

MYB118

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Transcription activator that recognizes the motif 5'-TAACGG-3' in the promoter of endosperm-induced genes (PubMed:27681170, PubMed:25194028, PubMed:19066902). Promotes vegetative-to-embryonic transition and the formation of somatic embryos from root explants in a WUS-independent manner but via the expression of embryonic genes (e.g. LEC1, LEC2, FUS3 and WUS) (PubMed:18695688). May play an important role during embryogenesis and seed maturation (PubMed:19066902, PubMed:25194028). Together with MYB115, activates the transcription of S-ACP-DES2/AAD2 and S-ACP-DES3/AAD3 thus promoting the biosynthesis of omega-7 monounsaturated fatty acid in seed endosperm (PubMed:27681170). Regulates negatively maturation genes in the endosperm (PubMed:25194028).4 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi212 – 235H-T-H motifPROSITE-ProRule annotationAdd BLAST24
DNA bindingi263 – 286H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor MYB1181 Publication
Alternative name(s):
Myb-related protein 1181 Publication
Short name:
AtMYB1181 Publication
Protein PLANT GROWTH ACTIVATOR 371 Publication
Gene namesi
Name:MYB1181 Publication
Synonyms:PGA371 Publication
Ordered Locus Names:At3g27785Imported
ORF Names:MGF10.18Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G27785
TAIRilocus:2829519 AT3G27785

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Single and myb118 myb115 double mutants do not show apparent developmental abnormalities (PubMed:18695688, PubMed:25194028). Reduced omega-7 fatty acids accumulation in the endosperm. The endosperm oil of double mutant myb115 myb118 lacks omega-7 fatty acids (PubMed:27681170). Endosperm-specific derepression of maturation-related genes associated with a partial relocation of storage compounds from the embryo to the endosperm (PubMed:25194028).3 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004386211 – 437Transcription factor MYB118Add BLAST437

Proteomic databases

PaxDbiQ9LVW4

Expressioni

Tissue specificityi

Mainly expressed in siliques (PubMed:18695688, PubMed:19066902). Also detected at low levels in leaves and flowers (PubMed:19066902).2 Publications

Developmental stagei

Expressed in embryos from the early heart stage and throughout embryogenesis (PubMed:18695688, PubMed:19066902). Induced at the onset of the maturation phase in the endosperm, in a high and homogeneous repartition (PubMed:18695688, PubMed:19066902, PubMed:25194028, PubMed:27681170).4 Publications

Inductioni

Induced by LEC2.1 Publication

Gene expression databases

ExpressionAtlasiQ9LVW4 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ9LVW4, 5 interactors
STRINGi3702.AT3G27785.1

Structurei

3D structure databases

ProteinModelPortaliQ9LVW4
SMRiQ9LVW4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini184 – 239HTH myb-type 1PROSITE-ProRule annotationAdd BLAST56
Domaini240 – 290HTH myb-type 2PROSITE-ProRule annotationAdd BLAST51

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi152 – 159Nuclear localization signalPROSITE-ProRule annotation8

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0048 Eukaryota
COG5147 LUCA
HOGENOMiHOG000202483
InParanoidiQ9LVW4
KOiK09422
OMAiQMRRICK
OrthoDBiEOG09360CM8
PhylomeDBiQ9LVW4

Family and domain databases

CDDicd00167 SANT, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017930 Myb_dom
IPR001005 SANT/Myb
SMARTiView protein in SMART
SM00717 SANT, 2 hits
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 2 hits

Sequencei

Sequence statusi: Complete.

Q9LVW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFESVFKMH YPYLAAVIYD DSSTLKDFHP SLTDDFSCVH NVHHKPSMPH
60 70 80 90 100
TYEIPSKETI RGITPSPCTE AFEACFHGTS NDHVFFGMAY TTPPTIEPNV
110 120 130 140 150
SHVSHDNTMW ENDQNQGFIF GTESTLNQAM ADSNQFNMPK PLLSANEDTI
160 170 180 190 200
MNRRQNNQVM IKTEQIKKKN KRFQMRRICK PTKKASIIKG QWTPEEDKLL
210 220 230 240 250
VQLVDLHGTK KWSQIAKMLQ GRVGKQCRER WHNHLRPDIK KDGWTEEEDI
260 270 280 290 300
ILIKAHKEIG NRWAEIARKL PGRTENTIKN HWNATKRRQH SRRTKGKDEI
310 320 330 340 350
SLSLGSNTLQ NYIRSVTYND DPFMTANANA NIGPRNMRGK GKNVMVAVSE
360 370 380 390 400
YDEGECKYIV DGVNNLGLED GRIKMPSLAA MSASGSASTS GSASGSGSGV
410 420 430
TMEIDEPMTD SWMVMHGCDE VMMNEIALLE MIAHGRL
Length:437
Mass (Da):49,492
Last modified:October 1, 2000 - v1
Checksum:i33F5959DD8728213
GO

Sequence cautioni

The sequence ABK28575 differs from that shown. Reason: Erroneous termination at position 438. Translated as stop.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti73E → G in AAS58517 (PubMed:16463103).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF334817 mRNA Translation: AAK25750.2
AY550306 mRNA Translation: AAS58517.1
AB018114 Genomic DNA Translation: BAB02701.1
CP002686 Genomic DNA Translation: AEE77363.1
DQ446708 mRNA Translation: ABE65974.1
DQ653111 mRNA Translation: ABK28575.1 Sequence problems.
RefSeqiNP_189416.2, NM_113694.2
UniGeneiAt.8032

Genome annotation databases

EnsemblPlantsiAT3G27785.1; AT3G27785.1; AT3G27785
GeneIDi822399
GrameneiAT3G27785.1; AT3G27785.1; AT3G27785
KEGGiath:AT3G27785

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF334817 mRNA Translation: AAK25750.2
AY550306 mRNA Translation: AAS58517.1
AB018114 Genomic DNA Translation: BAB02701.1
CP002686 Genomic DNA Translation: AEE77363.1
DQ446708 mRNA Translation: ABE65974.1
DQ653111 mRNA Translation: ABK28575.1 Sequence problems.
RefSeqiNP_189416.2, NM_113694.2
UniGeneiAt.8032

3D structure databases

ProteinModelPortaliQ9LVW4
SMRiQ9LVW4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9LVW4, 5 interactors
STRINGi3702.AT3G27785.1

Proteomic databases

PaxDbiQ9LVW4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G27785.1; AT3G27785.1; AT3G27785
GeneIDi822399
GrameneiAT3G27785.1; AT3G27785.1; AT3G27785
KEGGiath:AT3G27785

Organism-specific databases

AraportiAT3G27785
TAIRilocus:2829519 AT3G27785

Phylogenomic databases

eggNOGiKOG0048 Eukaryota
COG5147 LUCA
HOGENOMiHOG000202483
InParanoidiQ9LVW4
KOiK09422
OMAiQMRRICK
OrthoDBiEOG09360CM8
PhylomeDBiQ9LVW4

Miscellaneous databases

PROiPR:Q9LVW4

Gene expression databases

ExpressionAtlasiQ9LVW4 baseline and differential

Family and domain databases

CDDicd00167 SANT, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017930 Myb_dom
IPR001005 SANT/Myb
SMARTiView protein in SMART
SM00717 SANT, 2 hits
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiMY118_ARATH
AccessioniPrimary (citable) accession number: Q9LVW4
Secondary accession number(s): A0MEY8, Q6QAD0, Q9C5P8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 18, 2017
Last sequence update: October 1, 2000
Last modified: October 10, 2018
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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