UniProtKB - Q9LV21 (TCPD_ARATH)
Protein
T-complex protein 1 subunit delta
Gene
CCT4
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.Curated
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- unfolded protein binding Source: InterPro
GO - Biological processi
- protein folding Source: InterPro
- response to cadmium ion Source: TAIR
Keywordsi
Molecular function | Chaperone |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: T-complex protein 1 subunit delta1 PublicationShort name: TCP-1-delta1 Publication Alternative name(s): CCT-delta1 Publication Chaperonin CCT4Curated |
Gene namesi | Name:CCT4Curated Ordered Locus Names:At3g18190Imported ORF Names:MRC8 |
Organismi | Arabidopsis thaliana (Mouse-ear cress)Imported |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT3G18190 |
TAIRi | locus:2092697 AT3G18190 |
Subcellular locationi
Other locations
- Cytoplasm Curated
Cytosol
- chaperonin-containing T-complex Source: GO_Central
- cytosol Source: TAIR
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000431661 | 1 – 536 | T-complex protein 1 subunit deltaAdd BLAST | 536 |
Proteomic databases
PaxDbi | Q9LV21 |
PRIDEi | Q9LV21 |
PTM databases
iPTMneti | Q9LV21 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9LV21 baseline and differential |
Genevisiblei | Q9LV21 AT |
Interactioni
Subunit structurei
Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
1 PublicationGO - Molecular functioni
- unfolded protein binding Source: InterPro
Protein-protein interaction databases
IntActi | Q9LV21, 4 interactors |
STRINGi | 3702.AT3G18190.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the TCP-1 chaperonin family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0358 Eukaryota COG0459 LUCA |
HOGENOMi | HOG000226735 |
InParanoidi | Q9LV21 |
KOi | K09496 |
OMAi | TGIQNMG |
OrthoDBi | 511484at2759 |
PhylomeDBi | Q9LV21 |
Family and domain databases
CDDi | cd03338 TCP1_delta, 1 hit |
Gene3Di | 1.10.560.10, 2 hits 3.50.7.10, 1 hit |
InterProi | View protein in InterPro IPR012717 Chap_CCT_delta IPR017998 Chaperone_TCP-1 IPR002194 Chaperonin_TCP-1_CS IPR002423 Cpn60/TCP-1 IPR027409 GroEL-like_apical_dom_sf IPR027413 GROEL-like_equatorial_sf IPR027410 TCP-1-like_intermed_sf |
Pfami | View protein in Pfam PF00118 Cpn60_TCP1, 1 hit |
PRINTSi | PR00304 TCOMPLEXTCP1 |
SUPFAMi | SSF48592 SSF48592, 1 hit SSF52029 SSF52029, 1 hit SSF54849 SSF54849, 1 hit |
TIGRFAMsi | TIGR02342 chap_CCT_delta, 1 hit |
PROSITEi | View protein in PROSITE PS00750 TCP1_1, 1 hit PS00995 TCP1_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9LV21-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAVAAPMAS KPRGSKAESF VDNKRREDIR FANINSARAV SDAVRTSLGP
60 70 80 90 100
KGMDKMISTA NGEVIITNDG ATILNKMEVL QPAAKMLVEL SKSQDSAAGD
110 120 130 140 150
GTTTVVVIAG ALLKECQSLL TNGIHPTVIS DSLHKACGKA IDILTAMAVP
160 170 180 190 200
VELTDRDSLV KSASTSLNSK VVSQYSTLLA PLAVDAVLSV IDPEKPEIVD
210 220 230 240 250
LRDIKIVKKL GGTVDDTHTV KGLVFDKKVS RAAGGPTRVE NAKIAVIQFQ
260 270 280 290 300
ISPPKTDIEQ SIVVSDYTQM DRILKEERNY ILGMIKKIKA TGCNVLLIQK
310 320 330 340 350
SILRDAVTDL SLHYLAKAKI MVIKDVERDE IEFVTKTLNC LPIANIEHFR
360 370 380 390 400
AEKLGHADLV EEASLGDGKI LKITGIKDMG RTTSVLVRGS NQLVLDEAER
410 420 430 440 450
SLHDALCVVR CLVSKRFLIA GGGAPEIELS RQLGAWAKVL HGMEGYCVKS
460 470 480 490 500
FAEALEVIPY TLAENAGLNP IAIVTELRNK HAQGEINAGI NVRKGQITNI
510 520 530
LEENVVQPLL VSTSAITLAT ECVRMILKID DIVTVR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 8 | M → I in AAM66101 (Ref. 4) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB020749 Genomic DNA Translation: BAB02032.1 CP002686 Genomic DNA Translation: AEE76061.1 AY099877 mRNA Translation: AAM20728.1 BT003418 mRNA Translation: AAO30081.1 AY088570 mRNA Translation: AAM66101.1 |
RefSeqi | NP_188447.1, NM_112702.3 |
Genome annotation databases
EnsemblPlantsi | AT3G18190.1; AT3G18190.1; AT3G18190 |
GeneIDi | 821346 |
Gramenei | AT3G18190.1; AT3G18190.1; AT3G18190 |
KEGGi | ath:AT3G18190 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB020749 Genomic DNA Translation: BAB02032.1 CP002686 Genomic DNA Translation: AEE76061.1 AY099877 mRNA Translation: AAM20728.1 BT003418 mRNA Translation: AAO30081.1 AY088570 mRNA Translation: AAM66101.1 |
RefSeqi | NP_188447.1, NM_112702.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9LV21, 4 interactors |
STRINGi | 3702.AT3G18190.1 |
PTM databases
iPTMneti | Q9LV21 |
Proteomic databases
PaxDbi | Q9LV21 |
PRIDEi | Q9LV21 |
Genome annotation databases
EnsemblPlantsi | AT3G18190.1; AT3G18190.1; AT3G18190 |
GeneIDi | 821346 |
Gramenei | AT3G18190.1; AT3G18190.1; AT3G18190 |
KEGGi | ath:AT3G18190 |
Organism-specific databases
Araporti | AT3G18190 |
TAIRi | locus:2092697 AT3G18190 |
Phylogenomic databases
eggNOGi | KOG0358 Eukaryota COG0459 LUCA |
HOGENOMi | HOG000226735 |
InParanoidi | Q9LV21 |
KOi | K09496 |
OMAi | TGIQNMG |
OrthoDBi | 511484at2759 |
PhylomeDBi | Q9LV21 |
Miscellaneous databases
PROi | PR:Q9LV21 |
Gene expression databases
ExpressionAtlasi | Q9LV21 baseline and differential |
Genevisiblei | Q9LV21 AT |
Family and domain databases
CDDi | cd03338 TCP1_delta, 1 hit |
Gene3Di | 1.10.560.10, 2 hits 3.50.7.10, 1 hit |
InterProi | View protein in InterPro IPR012717 Chap_CCT_delta IPR017998 Chaperone_TCP-1 IPR002194 Chaperonin_TCP-1_CS IPR002423 Cpn60/TCP-1 IPR027409 GroEL-like_apical_dom_sf IPR027413 GROEL-like_equatorial_sf IPR027410 TCP-1-like_intermed_sf |
Pfami | View protein in Pfam PF00118 Cpn60_TCP1, 1 hit |
PRINTSi | PR00304 TCOMPLEXTCP1 |
SUPFAMi | SSF48592 SSF48592, 1 hit SSF52029 SSF52029, 1 hit SSF54849 SSF54849, 1 hit |
TIGRFAMsi | TIGR02342 chap_CCT_delta, 1 hit |
PROSITEi | View protein in PROSITE PS00750 TCP1_1, 1 hit PS00995 TCP1_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TCPD_ARATH | |
Accessioni | Q9LV21Primary (citable) accession number: Q9LV21 Secondary accession number(s): Q8L994 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 7, 2015 |
Last sequence update: | October 1, 2000 | |
Last modified: | October 16, 2019 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names