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Entry version 135 (31 Jul 2019)
Sequence version 1 (01 Oct 2000)
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Protein

Zinc finger CCCH domain-containing protein 66

Gene

At5g58620

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri254 – 276C3H1-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 308C3H1-type 2PROSITE-ProRule annotationAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger CCCH domain-containing protein 66
Short name:
AtC3H66
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At5g58620
ORF Names:MZN1.16, MZN1.8
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G58620

The Arabidopsis Information Resource

More...
TAIRi
locus:2178843 AT5G58620

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003720161 – 607Zinc finger CCCH domain-containing protein 66Add BLAST607

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9LUZ4

PRoteomics IDEntifications database

More...
PRIDEi
Q9LUZ4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9LUZ4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9LUZ4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9LUZ4 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
21220, 20 interactors

Protein interaction database and analysis system

More...
IntActi
Q9LUZ4, 20 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G58620.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9LUZ4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati57 – 87ANK 1Add BLAST31
Repeati92 – 124ANK 2Add BLAST33

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri254 – 276C3H1-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 308C3H1-type 2PROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

ANK repeat, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1595 Eukaryota
ENOG410XR0Z LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000240339

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9LUZ4

Identification of Orthologs from Complete Genome Data

More...
OMAi
AMMSPAW

Database of Orthologous Groups

More...
OrthoDBi
905042at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9LUZ4

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000571 Znf_CCCH

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit
PF00642 zf-CCCH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 2 hits
SM00356 ZnF_C3H1, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
PS50103 ZF_C3H1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9LUZ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVDELSHLK FSLLLESSAC NDLSGFKSLV EEEGLESIDG SGLWYGRRLG
60 70 80 90 100
SKKMGFEERT PLMIAALFGS KEVVDYIIST GLVDVNRSCG SDGATALHCA
110 120 130 140 150
VSGLSANSLE IVTLLLKGSA NPDSCDAYGN KPGDVIFPCL SPVFSARMKV
160 170 180 190 200
LERLLKGNDD LNEVNGQEES EPEVEVEVEV SPPRGSERKE YPVDPTLPDI
210 220 230 240 250
KNGVYGTDEF RMYAFKIKPC SRAYSHDWTE CPFVHPGENA RRRDPRKYHY
260 270 280 290 300
SCVPCPEFRK GSCSRGDTCE YAHGIFECWL HPAQYRTRLC KDETNCSRRV
310 320 330 340 350
CFFAHKPEEL RPLYPSTGSG VPSPRSSFSS CNSSTAFDMG PISPLPIGAT
360 370 380 390 400
TTPPLSPNGV SSPIGGGKTW MNWPNITPPA LQLPGSRLKS ALNAREIDFS
410 420 430 440 450
EEMQSLTSPT TWNNTPMSSP FSGKGMNRLA GGAMSPVNSL SDMFGTEDNT
460 470 480 490 500
SGLQIRRSVI NPQLHSNSLS SSPVGANSLF SMDSSAVLAS RAAEFAKQRS
510 520 530 540 550
QSFIERNNGL NHHPAISSMT TTCLNDWGSL DGKLDWSVQG DELQKLRKST
560 570 580 590 600
SFRLRAGGME SRLPNEGTGL EEPDVSWVEP LVKEPQETRL APVWMEQSYM

ETEQTVA
Length:607
Mass (Da):66,448
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8788E2D554335E7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB020755 Genomic DNA Translation: BAA97332.1
CP002688 Genomic DNA Translation: AED97077.1
AY054176 mRNA Translation: AAL06837.1
AY062491 mRNA Translation: AAL32569.1
AY103314 mRNA Translation: AAM65365.1
BT002083 mRNA Translation: AAN72094.1

NCBI Reference Sequences

More...
RefSeqi
NP_200670.1, NM_125249.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G58620.1; AT5G58620.1; AT5G58620

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
835976

Gramene; a comparative resource for plants

More...
Gramenei
AT5G58620.1; AT5G58620.1; AT5G58620

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G58620

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020755 Genomic DNA Translation: BAA97332.1
CP002688 Genomic DNA Translation: AED97077.1
AY054176 mRNA Translation: AAL06837.1
AY062491 mRNA Translation: AAL32569.1
AY103314 mRNA Translation: AAM65365.1
BT002083 mRNA Translation: AAN72094.1
RefSeqiNP_200670.1, NM_125249.3

3D structure databases

SMRiQ9LUZ4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi21220, 20 interactors
IntActiQ9LUZ4, 20 interactors
STRINGi3702.AT5G58620.1

PTM databases

iPTMnetiQ9LUZ4

Proteomic databases

PaxDbiQ9LUZ4
PRIDEiQ9LUZ4

Genome annotation databases

EnsemblPlantsiAT5G58620.1; AT5G58620.1; AT5G58620
GeneIDi835976
GrameneiAT5G58620.1; AT5G58620.1; AT5G58620
KEGGiath:AT5G58620

Organism-specific databases

AraportiAT5G58620
TAIRilocus:2178843 AT5G58620

Phylogenomic databases

eggNOGiKOG1595 Eukaryota
ENOG410XR0Z LUCA
HOGENOMiHOG000240339
InParanoidiQ9LUZ4
OMAiAMMSPAW
OrthoDBi905042at2759
PhylomeDBiQ9LUZ4

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9LUZ4

Gene expression databases

ExpressionAtlasiQ9LUZ4 baseline and differential
GenevisibleiQ9LUZ4 AT

Family and domain databases

Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF00642 zf-CCCH, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 2 hits
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
PS50103 ZF_C3H1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC3H66_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9LUZ4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: October 1, 2000
Last modified: July 31, 2019
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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