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Entry version 117 (31 Jul 2019)
Sequence version 1 (01 Oct 2000)
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Protein
Submitted name:

Chromosome condensation regulator-like protein protein

Gene
N/A
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri608 – 670FYVE-typePROSITE-ProRule annotationAdd BLAST63

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chromosome condensation regulator-like protein proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9LTC2 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini25 – 130PHInterPro annotationAdd BLAST106
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati220 – 278RCC1PROSITE-ProRule annotationAdd BLAST59
Repeati279 – 330RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati331 – 385RCC1PROSITE-ProRule annotationAdd BLAST55
Repeati386 – 437RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati448 – 499RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati500 – 551RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati552 – 603RCC1PROSITE-ProRule annotationAdd BLAST52
Domaini608 – 670FYVE-typeInterPro annotationAdd BLAST63
Domaini962 – 1017BRXInterPro annotationAdd BLAST56

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni679 – 736DisorderedSequence analysisAdd BLAST58
Regioni762 – 805DisorderedSequence analysisAdd BLAST44
Regioni913 – 966DisorderedSequence analysisAdd BLAST54
Regioni1016 – 1067DisorderedSequence analysisAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili808 – 849Sequence analysisAdd BLAST42
Coiled coili864 – 884Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi704 – 736PolarSequence analysisAdd BLAST33
Compositional biasi774 – 792Pro-richSequence analysisAdd BLAST19
Compositional biasi913 – 958PolarSequence analysisAdd BLAST46
Compositional biasi1016 – 1033PolarSequence analysisAdd BLAST18
Compositional biasi1043 – 1067PolarSequence analysisAdd BLAST25

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri608 – 670FYVE-typePROSITE-ProRule annotationAdd BLAST63

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHT4 Eukaryota
COG5184 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000240974

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9LTC2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.30, 2 hits
2.30.29.30, 1 hit
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013591 Brevis_radix_dom
IPR027988 BRX_N
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08381 BRX, 1 hit
PF13713 BRX_N, 1 hit
PF01363 FYVE, 1 hit
PF16457 PH_12, 1 hit
PF00415 RCC1, 6 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00633 RCCNDNSATION

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00064 FYVE, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50985 SSF50985, 1 hit
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51514 BRX, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50012 RCC1_3, 7 hits
PS50178 ZF_FYVE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9LTC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTDGMADPA SCYIYHERDV DQALVVLKKG TQLLKYSRKG KPKFRAFRLS
60 70 80 90 100
PDEKTLIWFS RGEEKGLKLF EVSRIVPGQR TAVFKRFLRP EKDHLSFSLL
110 120 130 140 150
YNNRERSLDL ICKDKAETEV WFAALKFLIE KSRNRRARSE IPEIHDSDTF
160 170 180 190 200
SVGRQSIDFV PSNIPRGRTS IDLGYQNNSD VGYERGNMLR PSTDGFRISV
210 220 230 240 250
SSTPSCSSGG SGPDDIESLG DVYVWGEVWT EGILPDGTAS NETVKTDVLT
260 270 280 290 300
PRPLESNVVL DVHQIVCGVR HVALVTRQGE VFTWGEEVGG RLGHGIQVDI
310 320 330 340 350
SRPKLVEFLA LTNIDFVACG EYHTCVVSTS GDLFSWGDGI HNVGLLGHGS
360 370 380 390 400
DISHWIPKRV SGPLEGLQVL SVACGTWHSA LATANGKLFT FGDGAFGVLG
410 420 430 440 450
HGNRESVSYP KEVQSLNGLK TVKVACSIWH TAAIVEVMGQ TATSMSSRKL
460 470 480 490 500
FTWGDGDKNR LGHGNKETYL LPTCVSSLID YNFHKIACGH TFTVALTTSG
510 520 530 540 550
HVFTMGGTAH GQLGNSISDG KLPCLVQDRL VGEFVEEIAC GAHHVAVLTS
560 570 580 590 600
RSEVFTWGKG ANGRLGHGDT EDKRTPTLVE ALRDRHVKSL SCGSNFTSSI
610 620 630 640 650
CIHKWVSGAD QSICSGCRQA FGFTRKRHNC YNCGLVHCHA CSSKKALKAA
660 670 680 690 700
LAPTPGKPHR VCDACYSKLK AAESGYSSNV NRNVATPGRS IDGSVRTDRE
710 720 730 740 750
TTRSSKVLLS ANKNSVMSSS RPGFTPESSN ARASQVPSLQ QLKDIAFPSS
760 770 780 790 800
LSAIQNAFKP VVAPTTTPPR TLVIGPSSPS PPPPPRSSSP YARRPSPPRT
810 820 830 840 850
SGFSRSVIDS LRKTNEVMNQ EMTKLHSQVK NLKQRCNNQG TEIERFQKAA
860 870 880 890 900
KDASELAARQ SSKHKAATEA LKSVAEQLKE LKEKLPPEVS ESEAFESINS
910 920 930 940 950
QAEAYLNANK VSETSPLTTS GQEQETYQKT EEQVPSNSSI TETSSSSRAP
960 970 980 990 1000
STEASSSRIS GKESKEQFEP GVYVTYEVDM NGNKIFRRVR FSKKRFDEHQ
1010 1020 1030 1040 1050
AEDWWTKNKD RLLKCYSSNS SSSSSSSNPT ASDSPVAPQP PSDPSLQKQN
1060
GEVVTTASTL SHVNSNV
Length:1,067
Mass (Da):116,492
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF5EC10B0BFF89013
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB025608 Genomic DNA Translation: BAA95740.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB025608 Genomic DNA Translation: BAA95740.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Phylogenomic databases

eggNOGiENOG410IHT4 Eukaryota
COG5184 LUCA
HOGENOMiHOG000240974
PhylomeDBiQ9LTC2

Gene expression databases

ExpressionAtlasiQ9LTC2 baseline and differential

Family and domain databases

Gene3Di2.130.10.30, 2 hits
2.30.29.30, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR013591 Brevis_radix_dom
IPR027988 BRX_N
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF08381 BRX, 1 hit
PF13713 BRX_N, 1 hit
PF01363 FYVE, 1 hit
PF16457 PH_12, 1 hit
PF00415 RCC1, 6 hits
PRINTSiPR00633 RCCNDNSATION
SMARTiView protein in SMART
SM00064 FYVE, 1 hit
SUPFAMiSSF50985 SSF50985, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS51514 BRX, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50012 RCC1_3, 7 hits
PS50178 ZF_FYVE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9LTC2_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9LTC2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: July 31, 2019
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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