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Protein

Peroxidase 30

Gene

PER30

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Catalytic activityi

2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.

Cofactori

Protein has several cofactor binding sites:
  • heme bPROSITE-ProRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.PROSITE-ProRule annotation
  • Ca2+PROSITE-ProRule annotationNote: Binds 2 calcium ions per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei65Transition state stabilizerPROSITE-ProRule annotation1
Active sitei69Proton acceptor1
Metal bindingi70Calcium 1PROSITE-ProRule annotation1
Metal bindingi73Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi75Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi77Calcium 1PROSITE-ProRule annotation1
Metal bindingi79Calcium 1PROSITE-ProRule annotation1
Binding sitei164Substrate; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi194Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi195Calcium 2PROSITE-ProRule annotation1
Metal bindingi247Calcium 2PROSITE-ProRule annotation1
Metal bindingi250Calcium 2PROSITE-ProRule annotation1
Metal bindingi255Calcium 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandCalcium, Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G21770-MONOMER

Protein family/group databases

PeroxiBasei123 AtPrx30

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxidase 30 (EC:1.11.1.7)
Short name:
Atperox P30
Alternative name(s):
ATP7a
PRXR9
Gene namesi
Name:PER30
Synonyms:P30
Ordered Locus Names:At3g21770
ORF Names:MSD21.10, MSD21.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G21770
TAIRilocus:2093099 AT3G21770

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000002369628 – 329Peroxidase 30Add BLAST302

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi38 ↔ 116PROSITE-ProRule annotation
Disulfide bondi71 ↔ 76PROSITE-ProRule annotation
Glycosylationi83N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi122 ↔ 324PROSITE-ProRule annotation
Glycosylationi155N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi201 ↔ 234PROSITE-ProRule annotation
Glycosylationi210N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi240N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi290N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9LSY7
PRIDEiQ9LSY7

Expressioni

Tissue specificityi

Mainly expressed in roots.2 Publications

Inductioni

By high salinity stress.

Gene expression databases

ExpressionAtlasiQ9LSY7 baseline and differential
GenevisibleiQ9LSY7 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G21770.1

Structurei

3D structure databases

ProteinModelPortaliQ9LSY7
SMRiQ9LSY7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IFQR Eukaryota
ENOG410Y9ME LUCA
HOGENOMiHOG000237556
KOiK00430
OMAiDSANKCK
OrthoDBiEOG09360FKB
PhylomeDBiQ9LSY7

Family and domain databases

CDDicd00693 secretory_peroxidase, 1 hit
InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR000823 Peroxidase_pln
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS
IPR033905 Secretory_peroxidase
PfamiView protein in Pfam
PF00141 peroxidase, 1 hit
PRINTSiPR00458 PEROXIDASE
PR00461 PLPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LSY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTMTQLNIA VVVVVTVLIG MLRSSEAQLQ MNFYAKSCPN AEKIISDHIQ
60 70 80 90 100
NHIHNGPSLA APLIRMHFHD CFVRGCDGSV LINSTSGNAE RDAPPNLTLR
110 120 130 140 150
GFGFVERIKA LLEKVCPKTV SCADIIALTA RDAVVATGGP SWSVPTGRRD
160 170 180 190 200
GRISNKTEAT NNIPPPTSNF TTLQRLFKNQ GLNLKDLVLL SGAHTIGVSH
210 220 230 240 250
CSSMNTRLYN FSTTVKQDPS LDSQYAANLK ANKCKSLNDN STILEMDPGS
260 270 280 290 300
SRSFDLSYYR LVLKRRGLFQ SDSALTTNSA TLKVINDLVN GSEKKFFKAF
310 320
AKSMEKMGRV KVKTGSAGVI RTRCSVAGS
Length:329
Mass (Da):35,788
Last modified:October 1, 2000 - v1
Checksum:i78CE6941617393A0
GO

Sequence cautioni

The sequence AAM61382 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAA67360 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti133A → T in AAM61382 (Ref. 6) Curated1
Sequence conflicti156 – 157KT → LK in AAM61382 (Ref. 6) Curated2
Sequence conflicti174Q → R in AAM61382 (Ref. 6) Curated1
Sequence conflicti329S → N (Ref. 1) Curated1
Sequence conflicti329S → N (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X98321 mRNA Translation: CAA66965.1
X98854 mRNA Translation: CAA67360.1 Different initiation.
AB025634 Genomic DNA Translation: BAB02839.1
CP002686 Genomic DNA Translation: AEE76550.1
AY072326 mRNA Translation: AAL61933.1
AY114567 mRNA Translation: AAM47886.1
AY084816 mRNA Translation: AAM61382.1 Different initiation.
RefSeqiNP_188814.1, NM_113072.2
UniGeneiAt.25181

Genome annotation databases

EnsemblPlantsiAT3G21770.1; AT3G21770.1; AT3G21770
GeneIDi821731
GrameneiAT3G21770.1; AT3G21770.1; AT3G21770
KEGGiath:AT3G21770

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X98321 mRNA Translation: CAA66965.1
X98854 mRNA Translation: CAA67360.1 Different initiation.
AB025634 Genomic DNA Translation: BAB02839.1
CP002686 Genomic DNA Translation: AEE76550.1
AY072326 mRNA Translation: AAL61933.1
AY114567 mRNA Translation: AAM47886.1
AY084816 mRNA Translation: AAM61382.1 Different initiation.
RefSeqiNP_188814.1, NM_113072.2
UniGeneiAt.25181

3D structure databases

ProteinModelPortaliQ9LSY7
SMRiQ9LSY7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G21770.1

Protein family/group databases

PeroxiBasei123 AtPrx30

Proteomic databases

PaxDbiQ9LSY7
PRIDEiQ9LSY7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G21770.1; AT3G21770.1; AT3G21770
GeneIDi821731
GrameneiAT3G21770.1; AT3G21770.1; AT3G21770
KEGGiath:AT3G21770

Organism-specific databases

AraportiAT3G21770
TAIRilocus:2093099 AT3G21770

Phylogenomic databases

eggNOGiENOG410IFQR Eukaryota
ENOG410Y9ME LUCA
HOGENOMiHOG000237556
KOiK00430
OMAiDSANKCK
OrthoDBiEOG09360FKB
PhylomeDBiQ9LSY7

Enzyme and pathway databases

BioCyciARA:AT3G21770-MONOMER

Miscellaneous databases

PROiPR:Q9LSY7

Gene expression databases

ExpressionAtlasiQ9LSY7 baseline and differential
GenevisibleiQ9LSY7 AT

Family and domain databases

CDDicd00693 secretory_peroxidase, 1 hit
InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR000823 Peroxidase_pln
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS
IPR033905 Secretory_peroxidase
PfamiView protein in Pfam
PF00141 peroxidase, 1 hit
PRINTSiPR00458 PEROXIDASE
PR00461 PLPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPER30_ARATH
AccessioniPrimary (citable) accession number: Q9LSY7
Secondary accession number(s): Q43737, Q96521
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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Main funding by: National Institutes of Health

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