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Protein

ABC transporter B family member 16

Gene

ABCB16

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi381 – 388ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1016 – 1023ATP 2PROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G28360-MONOMER
ReactomeiR-ATH-159418 Recycling of bile acids and salts
R-ATH-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
R-ATH-382556 ABC-family proteins mediated transport

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 16
Short name:
ABC transporter ABCB.16
Short name:
AtABCB16
Alternative name(s):
Multidrug resistance protein 18
P-glycoprotein 16
Gene namesi
Name:ABCB16
Synonyms:MDR18, PGP16
Ordered Locus Names:At3g28360
ORF Names:MFJ20.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G28360
TAIRilocus:2088912 AT3G28360

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei69 – 89HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei145 – 167HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei171 – 193HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei251 – 271HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei283 – 303HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei667 – 687HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei700 – 720HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei781 – 801HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei805 – 825HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei881 – 901HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei920 – 940HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002279291 – 1228ABC transporter B family member 16Add BLAST1228

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi529N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi593N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi628N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi755N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi827N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1001N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LSJ8
PRIDEiQ9LSJ8

Expressioni

Gene expression databases

GenevisibleiQ9LSJ8 AT

Interactioni

Protein-protein interaction databases

BioGridi7794, 7 interactors
STRINGi3702.AT3G28360.1

Structurei

3D structure databases

ProteinModelPortaliQ9LSJ8
SMRiQ9LSJ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 311ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST290
Domaini346 – 582ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini658 – 946ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST289
Domaini981 – 1219ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055 Eukaryota
COG1132 LUCA
InParanoidiQ9LSJ8
KOiK05658
OMAiCYPSRPK
OrthoDBiEOG093600PV
PhylomeDBiQ9LSJ8

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q9LSJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTWGSMRSI FMHADGVDWM LMGLGLIGAV GDGFITPILF FITAMLLNDF
60 70 80 90 100
GSFSFNDETF MQPISKNALA MLYVACASWV ICFLEGYCWT RTGERQAAKM
110 120 130 140 150
RERYLRAVLR QDVGYFDLHV TSTSDIITSV SSDSLVIQDF LSEKLPNILM
160 170 180 190 200
NASAFVGSYI VGFMLLWRLT IVGFPFIILL LIPGLMYGRA LIGISRKIRE
210 220 230 240 250
EYNEAGSIAE QAISSVRTVY AFVSEKKMIE KFSDALQGSV KLGLRQGLAK
260 270 280 290 300
GIAIGSNGIV YAIWGFLTWY GSRMVMNYGY KGGTVSTVTV CVTFGGTALG
310 320 330 340 350
QALSNLKYFS EAFVAGERIQ KMIKRVPDID SDNLNGHILE TIRGEVEFNN
360 370 380 390 400
VKCKYPSRPE TLIFDDLCLK IPSGKTVALV GGSGSGKSTV ISLLQRFYDP
410 420 430 440 450
NEGDILIDSV SINNMQVKWL RSQMGMVSQE PSLFATSIKE NILFGKEDAS
460 470 480 490 500
FDEVVEAAKA SNAHNFISQF PHGYQTQVGE RGVHMSGGQK QRIAIARALI
510 520 530 540 550
KSPIILLLDE ATSALDLESE RVVQEALDNA SVGRTTIVIA HRLSTIRNAD
560 570 580 590 600
IICVLHNGCI VETGSHDKLM EIDGKYTSLV RLQQMKNEES CDNTSVGVKE
610 620 630 640 650
GRVSSLRNDL DYNPRDLAHS MSSSIVTNLS DSIPQDKKPL VPSFKRLMAM
660 670 680 690 700
NRPEWKHALC GCLSASLGGA VQPIYAYSSG LMISVFFLTN HEQIKENTRI
710 720 730 740 750
YVLLFFGLAL FTFFTSISQQ YSFSYMGEYL TKRIREQMLS KILTFEVNWF
760 770 780 790 800
DEEENSSGAI CSRLAKDANV VRSLVGERMS LLVQTISTVM VACTIGLVIA
810 820 830 840 850
WRFTIVMISV QPVIIVCYYI QRVLLKNMSK KAIIAQDESS KLAAEAVSNI
860 870 880 890 900
RTITTFSSQE RIMKLLERVQ EGPRRESARQ SWLAGIMLGT TQSLITCTSA
910 920 930 940 950
LNFWYGGKLI ADGKMVSKAF FELFLIFKTT GRAIAEAGTM TTDLAKGSNS
960 970 980 990 1000
VDSVFTVLDR RTTIEPENPD GYILEKIKGQ ITFLNVDFAY PTRPNMVIFN
1010 1020 1030 1040 1050
NFSIEIHEGK STAIVGPSRS GKSTVIGLIE RFYDPLQGIV KIDGRDIRSY
1060 1070 1080 1090 1100
HLRSLRQHMS LVSQEPTLFA GTIRENIMYG RASNKIDESE IIEAGKTANA
1110 1120 1130 1140 1150
HEFITSLSDG YDTYCGDRGV QLSGGQKQRI AIARTILKNP SILLLDEATS
1160 1170 1180 1190 1200
ALDSQSERVV QDALEHVMVG KTSVVIAHRL STIQNCDTIA VLDKGKVVES
1210 1220
GTHASLLAKG PTGSYFSLVS LQRKVRYV
Length:1,228
Mass (Da):135,916
Last modified:October 1, 2000 - v1
Checksum:iB1FE531C4DF920CB
GO

Sequence cautioni

The sequence AAL91219 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026644 Genomic DNA Translation: BAB02852.1
CP002686 Genomic DNA Translation: AEE77437.1
AY081330 mRNA Translation: AAL91219.1 Different initiation.
BT008368 mRNA Translation: AAP37727.1
RefSeqiNP_189477.4, NM_113756.5
UniGeneiAt.42811

Genome annotation databases

EnsemblPlantsiAT3G28360.1; AT3G28360.1; AT3G28360
GeneIDi822465
GrameneiAT3G28360.1; AT3G28360.1; AT3G28360
KEGGiath:AT3G28360

Similar proteinsi

Entry informationi

Entry nameiAB16B_ARATH
AccessioniPrimary (citable) accession number: Q9LSJ8
Secondary accession number(s): Q8RXD2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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