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Protein

Glutathione S-transferase U15

Gene

GSTU15

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Enzyme and pathway databases

BioCyciARA:AT1G59670-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U15 (EC:2.5.1.18)
Short name:
AtGSTU15
Alternative name(s):
GST class-tau member 15
Gene namesi
Name:GSTU15
Ordered Locus Names:At1g59670
ORF Names:T30E16.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G59670
TAIRilocus:2202897 AT1G59670

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135611 – 233Glutathione S-transferase U15Add BLAST233

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei158PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LQ48
PRIDEiQ9LQ48

Expressioni

Gene expression databases

ExpressionAtlasiQ9LQ48 differential
GenevisibleiQ9LQ48 AT

Interactioni

Protein-protein interaction databases

BioGridi27482, 1 interactor
STRINGi3702.AT1G59670.1

Structurei

3D structure databases

ProteinModelPortaliQ9LQ48
SMRiQ9LQ48
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 85GST N-terminalAdd BLAST81
Domaini92 – 219GST C-terminalAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni15 – 16Glutathione bindingBy similarity2
Regioni42 – 43Glutathione bindingBy similarity2
Regioni56 – 57Glutathione bindingBy similarity2
Regioni69 – 70Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
HOGENOMiHOG000125749
InParanoidiQ9LQ48
KOiK00799
OMAiFVDDKVG
OrthoDBiEOG09360N01
PhylomeDBiQ9LQ48

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LQ48-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEREEVKLL GTWYSPVVIR AKIALRLKSV DYDYVEEDLF GSKSELLLKS
60 70 80 90 100
NPIFKKVPVL IHNTKPVCVS LNIVEYIDET WNSSGSSILP SHPYDRALAR
110 120 130 140 150
FWSVFVDDKW LPTLMAAVVA KSEEAKAKGM EEVEEGLLQL EAAFIALSKG
160 170 180 190 200
KSFFGGETIG FIDICLGSFL VLLKAREKLK NEKILDELKT PSLYRWANQF
210 220 230
LSNEMVKNVV PDIDKVAKFI EEFEDRAQYI RCF
Length:233
Mass (Da):26,535
Last modified:October 1, 2000 - v1
Checksum:i8722CA2CE7AEC09D
GO

Sequence cautioni

The sequence ABK28444 differs from that shown. Reason: Erroneous termination at position 234. Translated as stop.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6E → Q in AAM61551 (Ref. 4) Curated1
Sequence conflicti24A → D in AAM61551 (Ref. 4) Curated1
Sequence conflicti38D → N in AAM61551 (Ref. 4) Curated1
Sequence conflicti53 – 54IF → VY in AAM61551 (Ref. 4) Curated2
Sequence conflicti141E → D in AAM61551 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009317 Genomic DNA Translation: AAF79758.1
CP002684 Genomic DNA Translation: AEE33601.1
DQ446376 mRNA Translation: ABE65725.1
DQ652904 mRNA Translation: ABK28444.1 Sequence problems.
AY084992 mRNA Translation: AAM61551.1
PIRiD96620
RefSeqiNP_176176.1, NM_104660.2
UniGeneiAt.36811

Genome annotation databases

EnsemblPlantsiAT1G59670.1; AT1G59670.1; AT1G59670
GeneIDi842257
GrameneiAT1G59670.1; AT1G59670.1; AT1G59670
KEGGiath:AT1G59670

Similar proteinsi

Entry informationi

Entry nameiGSTUF_ARATH
AccessioniPrimary (citable) accession number: Q9LQ48
Secondary accession number(s): A0MED4, Q8LF83
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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