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UniProtKB - Q9LND8 (ADSL2_ARATH)
Protein
Delta-9 desaturase-like 2 protein
Gene
At1g06100
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Cofactori
Fe cationBy similarity
: polyunsaturated fatty acid biosynthesis Pathwayi
This protein is involved in the pathway polyunsaturated fatty acid biosynthesis, which is part of Lipid metabolism.View all proteins of this organism that are known to be involved in the pathway polyunsaturated fatty acid biosynthesis and in Lipid metabolism.
GO - Molecular functioni
- 16:0 monogalactosyldiacylglycerol desaturase activity Source: GO_Central
- oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Source: InterPro
GO - Biological processi
- unsaturated fatty acid biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Ligand | Iron |
Enzyme and pathway databases
BioCyci | ARA:AT1G06100-MONOMER |
UniPathwayi | UPA00658 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:At1g06100 ORF Names:T21E18.15, T21E18_12 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G06100 |
TAIRi | locus:2198816, AT1G06100 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane By similarity; Multi-pass membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 55 – 75 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 174 – 194 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 262 – 282 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000185428 | 1 – 299 | Delta-9 desaturase-like 2 proteinAdd BLAST | 299 |
Proteomic databases
PaxDbi | Q9LND8 |
ProteomicsDBi | 244840 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9LND8, baseline and differential |
Genevisiblei | Q9LND8, AT |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 77 – 82 | Histidine box-1 | 6 | |
Motifi | 114 – 118 | Histidine box-2 | 5 | |
Motifi | 246 – 250 | Histidine box-3 | 5 |
Domaini
The histidine box domains may contain the active site and/or be involved in metal ion binding.By similarity
Sequence similaritiesi
Belongs to the fatty acid desaturase type 1 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1600, Eukaryota |
HOGENOMi | CLU_027359_1_0_1 |
InParanoidi | Q9LND8 |
OMAi | FLFSAKW |
OrthoDBi | 971318at2759 |
PhylomeDBi | Q9LND8 |
Family and domain databases
CDDi | cd03505, Delta9-FADS-like, 1 hit |
InterProi | View protein in InterPro IPR015876, Acyl-CoA_DS IPR005804, FA_desaturase_dom |
PANTHERi | PTHR11351, PTHR11351, 1 hit |
Pfami | View protein in Pfam PF00487, FA_desaturase, 1 hit |
PRINTSi | PR00075, FACDDSATRASE |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9LND8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSETTKDDGS SQKKSVRKEK RAYVLRKWTQ FDVGRASTVG TVHLLCLLAP
60 70 80 90 100
FNYKWEAFRF GIILAILTNL CITFSYHRNL THRSFKLPKW LEYPFAYSAL
110 120 130 140 150
LALQGDPLDW VSIHRFHHQF TDSDRDPHSP IEGFWFSHVL WIFDTDYIRE
160 170 180 190 200
KCGRRNNVMD LKQQWFYRFL KKTLVLHILA FWTLIYLWGG LPYLTWTVGF
210 220 230 240 250
GGVIGYHGTW LVNSACHICG SQAWQTNDTS RNVWWLALLT MGESWHNNHH
260 270 280 290
AFETSARHGL EWYQLDITWY LIWFFQALGL ATNVKLPTDA QKRKMAIRR
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ9LNE0 | Q9LNE0_ARATH | At1g06070 | bZIP69 AtbZIP69, basic leucine-zipper 69, At1g06070, T21E18.12, T21E18_12 | 423 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC024174 Genomic DNA Translation: AAF80133.1 CP002684 Genomic DNA Translation: AEE27939.1 BT014933 mRNA Translation: AAT47784.1 BT015835 mRNA Translation: AAU94398.1 |
PIRi | C86196 |
RefSeqi | NP_172100.1, NM_100491.2 |
Genome annotation databases
EnsemblPlantsi | AT1G06100.1; AT1G06100.1; AT1G06100 |
GeneIDi | 837119 |
Gramenei | AT1G06100.1; AT1G06100.1; AT1G06100 |
KEGGi | ath:AT1G06100 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC024174 Genomic DNA Translation: AAF80133.1 CP002684 Genomic DNA Translation: AEE27939.1 BT014933 mRNA Translation: AAT47784.1 BT015835 mRNA Translation: AAU94398.1 |
PIRi | C86196 |
RefSeqi | NP_172100.1, NM_100491.2 |
3D structure databases
SMRi | Q9LND8 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT1G06100.1 |
Proteomic databases
PaxDbi | Q9LND8 |
ProteomicsDBi | 244840 |
Genome annotation databases
EnsemblPlantsi | AT1G06100.1; AT1G06100.1; AT1G06100 |
GeneIDi | 837119 |
Gramenei | AT1G06100.1; AT1G06100.1; AT1G06100 |
KEGGi | ath:AT1G06100 |
Organism-specific databases
Araporti | AT1G06100 |
TAIRi | locus:2198816, AT1G06100 |
Phylogenomic databases
eggNOGi | KOG1600, Eukaryota |
HOGENOMi | CLU_027359_1_0_1 |
InParanoidi | Q9LND8 |
OMAi | FLFSAKW |
OrthoDBi | 971318at2759 |
PhylomeDBi | Q9LND8 |
Enzyme and pathway databases
UniPathwayi | UPA00658 |
BioCyci | ARA:AT1G06100-MONOMER |
Miscellaneous databases
PROi | PR:Q9LND8 |
Gene expression databases
ExpressionAtlasi | Q9LND8, baseline and differential |
Genevisiblei | Q9LND8, AT |
Family and domain databases
CDDi | cd03505, Delta9-FADS-like, 1 hit |
InterProi | View protein in InterPro IPR015876, Acyl-CoA_DS IPR005804, FA_desaturase_dom |
PANTHERi | PTHR11351, PTHR11351, 1 hit |
Pfami | View protein in Pfam PF00487, FA_desaturase, 1 hit |
PRINTSi | PR00075, FACDDSATRASE |
MobiDBi | Search... |
Entry informationi
Entry namei | ADSL2_ARATH | |
Accessioni | Q9LND8Primary (citable) accession number: Q9LND8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 12, 2005 |
Last sequence update: | October 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 125 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families