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UniProtKB - Q9LMI4 (ADSL4_ARATH)
Protein
Delta-9 desaturase-like 4 protein
Gene
At1g06350
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Cofactori
Fe cationBy similarity
: polyunsaturated fatty acid biosynthesis Pathwayi
This protein is involved in the pathway polyunsaturated fatty acid biosynthesis, which is part of Lipid metabolism.View all proteins of this organism that are known to be involved in the pathway polyunsaturated fatty acid biosynthesis and in Lipid metabolism.
GO - Molecular functioni
- 16:0 monogalactosyldiacylglycerol desaturase activity Source: GO_Central
- oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Source: InterPro
GO - Biological processi
- response to red light Source: UniProtKB
- unsaturated fatty acid biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Ligand | Iron |
Enzyme and pathway databases
BioCyci | ARA:AT1G06350-MONOMER |
UniPathwayi | UPA00658 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:At1g06350 ORF Names:T2D23.5, T2D23_16 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G06350 |
TAIRi | locus:2202305, AT1G06350 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane By similarity; Multi-pass membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 39 – 59 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 61 – 81 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 175 – 195 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 200 – 220 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000185430 | 1 – 300 | Delta-9 desaturase-like 4 proteinAdd BLAST | 300 |
Proteomic databases
PaxDbi | Q9LMI4 |
ProteomicsDBi | 243284 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9LMI4, baseline and differential |
Genevisiblei | Q9LMI4, AT |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 78 – 83 | Histidine box-1 | 6 | |
Motifi | 115 – 119 | Histidine box-2 | 5 | |
Motifi | 247 – 251 | Histidine box-3 | 5 |
Domaini
The histidine box domains may contain the active site and/or be involved in metal ion binding.By similarity
Sequence similaritiesi
Belongs to the fatty acid desaturase type 1 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1600, Eukaryota |
HOGENOMi | CLU_027359_1_0_1 |
InParanoidi | Q9LMI4 |
OMAi | DAEIKWN |
OrthoDBi | 971318at2759 |
PhylomeDBi | Q9LMI4 |
Family and domain databases
CDDi | cd03505, Delta9-FADS-like, 1 hit |
InterProi | View protein in InterPro IPR015876, Acyl-CoA_DS IPR005804, FA_desaturase_dom |
PANTHERi | PTHR11351, PTHR11351, 1 hit |
Pfami | View protein in Pfam PF00487, FA_desaturase, 1 hit |
PRINTSi | PR00075, FACDDSATRASE |
i Sequence
Sequence statusi: Complete.
Q9LMI4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCDPTRDDGS SRSRVVSTMQ KRAYFQRQWP LVDVVRASVV VIVHFLCLLA
60 70 80 90 100
PFNFKWEALR FGLVLFALTT LSITFSFHRN LSHRSFKIPK WLEYPWAYSA
110 120 130 140 150
VFALQGDPMD WVSIHRFHHQ FTDSDRDPHS PKEGLLFSHI LWIFDTQYIK
160 170 180 190 200
YKCGGRDNVL DLKKQWFYKF LRRTIAVHIL MFWTILYLYG GLPYLTCGGG
210 220 230 240 250
VGIFIGYHVT WLVNSACHIW GSRSWNTKDT SRNVWWLSLF TMGESWHNNH
260 270 280 290 300
HAFESSARQG LEWWQIDITW YLIRLFEVLG IATDVKLPSE LQKQKMALVR
Sequence cautioni
The sequence AAF82163 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BT005732 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068143 Genomic DNA Translation: AAF82163.1 Sequence problems. CP002684 Genomic DNA Translation: AEE27977.1 BT005732 mRNA No translation available. |
PIRi | C86199 |
RefSeqi | NP_172124.2, NM_100516.4 |
Genome annotation databases
EnsemblPlantsi | AT1G06350.1; AT1G06350.1; AT1G06350 |
GeneIDi | 837146 |
Gramenei | AT1G06350.1; AT1G06350.1; AT1G06350 |
KEGGi | ath:AT1G06350 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068143 Genomic DNA Translation: AAF82163.1 Sequence problems. CP002684 Genomic DNA Translation: AEE27977.1 BT005732 mRNA No translation available. |
PIRi | C86199 |
RefSeqi | NP_172124.2, NM_100516.4 |
3D structure databases
SMRi | Q9LMI4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT1G06350.1 |
Proteomic databases
PaxDbi | Q9LMI4 |
ProteomicsDBi | 243284 |
Genome annotation databases
EnsemblPlantsi | AT1G06350.1; AT1G06350.1; AT1G06350 |
GeneIDi | 837146 |
Gramenei | AT1G06350.1; AT1G06350.1; AT1G06350 |
KEGGi | ath:AT1G06350 |
Organism-specific databases
Araporti | AT1G06350 |
TAIRi | locus:2202305, AT1G06350 |
Phylogenomic databases
eggNOGi | KOG1600, Eukaryota |
HOGENOMi | CLU_027359_1_0_1 |
InParanoidi | Q9LMI4 |
OMAi | DAEIKWN |
OrthoDBi | 971318at2759 |
PhylomeDBi | Q9LMI4 |
Enzyme and pathway databases
UniPathwayi | UPA00658 |
BioCyci | ARA:AT1G06350-MONOMER |
Miscellaneous databases
PROi | PR:Q9LMI4 |
Gene expression databases
ExpressionAtlasi | Q9LMI4, baseline and differential |
Genevisiblei | Q9LMI4, AT |
Family and domain databases
CDDi | cd03505, Delta9-FADS-like, 1 hit |
InterProi | View protein in InterPro IPR015876, Acyl-CoA_DS IPR005804, FA_desaturase_dom |
PANTHERi | PTHR11351, PTHR11351, 1 hit |
Pfami | View protein in Pfam PF00487, FA_desaturase, 1 hit |
PRINTSi | PR00075, FACDDSATRASE |
MobiDBi | Search... |
Entry informationi
Entry namei | ADSL4_ARATH | |
Accessioni | Q9LMI4Primary (citable) accession number: Q9LMI4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 12, 2005 |
Last sequence update: | October 14, 2008 | |
Last modified: | February 23, 2022 | |
This is version 126 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families