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Entry version 152 (29 Sep 2021)
Sequence version 1 (01 Oct 2000)
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Protein

ABC transporter C family member 3

Gene

ABCC3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Pump for glutathione S-conjugates. Mediates the transport of glutathione conjugates such as chlorodinitrobenzene-GS (DNB-GS), and of chlorophyll catabolites such as Bn-NCC-1. Transports also heavy metals such as cadmium (Cd).

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2). EC:7.6.2.2

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Glutathione-conjugate transport is inhibited by decyl-glutathione and, to a lower extent, by GS-GS, but not by GSH. All transports are inhibited by vanadate.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=100 µM for DNB-GS (at pH 7.4 and 25 degrees Celsius)1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi675 – 682ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1303 – 1310ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • transmembrane transport Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT3G13080-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.208.17, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ABC transporter C family member 3 (EC:7.6.2.2)
Short name:
ABC transporter ABCC.3
Short name:
AtABCC3
Alternative name(s):
ATP-energized glutathione S-conjugate pump 3
Glutathione S-conjugate-transporting ATPase 3
Multidrug resistance-associated protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCC3
Synonyms:EST2, MRP3
Ordered Locus Names:At3g13080
ORF Names:MJG19.3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G13080

The Arabidopsis Information Resource

More...
TAIRi
locus:2090029, AT3G13080

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei83 – 103HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei116 – 136HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei153 – 173HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei183 – 203HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei325 – 345HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei364 – 386HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei439 – 459HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei463 – 483HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei551 – 571HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei940 – 960HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei987 – 1007HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1077 – 1097HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1181 – 1201HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1205 – 1225HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002260741 – 1514ABC transporter C family member 3Add BLAST1514

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9LK64

PRoteomics IDEntifications database

More...
PRIDEi
Q9LK64

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
244605 [Q9LK64-1]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous.2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By 1-chloro-2,4-dinitrobenzene (CDNB), primisulfuron (PS), aminotriazole, benoxacor, oxabetrinil and IRL 1803, and, to a lower extent, by cloquintocet, fenchlorazol and fluorazol.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9LK64, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9LK64, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT3G13080.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9LK64

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini325 – 606ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST282
Domaini640 – 863ABC transporter 1PROSITE-ProRule annotationAdd BLAST224
Domaini950 – 1232ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST283
Domaini1271 – 1503ABC transporter 2PROSITE-ProRule annotationAdd BLAST233

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0054, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000604_27_3_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9LK64

Identification of Orthologs from Complete Genome Data

More...
OMAi
LDYECSE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9LK64

Family and domain databases

Conserved Domains Database

More...
CDDi
cd18579, ABC_6TM_ABCC_D1, 1 hit
cd18580, ABC_6TM_ABCC_D2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits
3.40.50.300, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR011527, ABC1_TM_dom
IPR036640, ABC1_TM_sf
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR044746, ABCC_6TM_D1
IPR044726, ABCC_6TM_D2
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664, ABC_membrane, 2 hits
PF00005, ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits
SSF90123, SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929, ABC_TM1F, 2 hits
PS00211, ABC_TRANSPORTER_1, 1 hit
PS50893, ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9LK64-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDFLGSTTGS GTLAMLFSFS ESILPLDSRS FLLKPLFLRW LSGFLHSVLL
60 70 80 90 100
LVLFFSWVRK KIRGDSGVTE SLKDRRDFGF KSALFCSLAL SLLNLVLMSL
110 120 130 140 150
SGFYWYESGW LDNEQLVSSL GFLLGMVSWG VLSICLHRCR DCEHKKAPFL
160 170 180 190 200
LRLWLVFYLV VSCYSLVVDF VMYERRETVP VHLLVFDIVA FIAAVFLGYV
210 220 230 240 250
AVLKKDRSNS NGVLEEPLLN GGDSRVGGDD SVELNKTNGS GEATPYSRAG
260 270 280 290 300
ILSLLTFSWM SPLIDIGNKK TLDLEDVPQL HDTDSVVGLA PKFRSMLESP
310 320 330 340 350
DGGERSGVTT FKLIKALYFT AQWEILVTAF FAFIYTVASY VGPALIDTFV
360 370 380 390 400
QYLNGRRQYN HEGYVLVITF FAAKIVECLS QRHWFFRLQK VGIRMRSALV
410 420 430 440 450
AMIYEKGLTL SCQSKQGRTS GEIINFMTVD AERIGNFSWY MHDPWMVLLQ
460 470 480 490 500
VGLALWILYR NLGLASIAAL VATIIVMLIN FPFGRMQERF QEKLMEAKDS
510 520 530 540 550
RMKSTSEILR NMRILKLQGW EMKFLSKIFD LRKSEEGWLK KYVYNSAVIS
560 570 580 590 600
FVFWGAPTLV SVSTFGACIL LGIPLESGKI LSALATFRIL QEPIYNLPDT
610 620 630 640 650
ISMIVQTKVS LDRLASYLCL DNLQPDIVER LPKGSSDVAV EVINSTLSWD
660 670 680 690 700
VSSSNPTLKD INFKVFPGMK VAVCGTVGSG KSSLLSSLLG EVPKVSGSLK
710 720 730 740 750
VCGTKAYVAQ SPWIQSGKIE DNILFGKPME RERYDKVLEA CSLSKDLEIL
760 770 780 790 800
SFGDQTVIGE RGINLSGGQK QRIQIARALY QDADIYLFDD PFSAVDAHTG
810 820 830 840 850
SHLFKEVLLG LLCSKSVIYV THQVEFLPAA DLILVMKDGR ISQAGKYNDI
860 870 880 890 900
LNSGTDFMEL IGAHQEALAV VDSVDANSVS EKSALGQENV IVKDAIAVDE
910 920 930 940 950
KLESQDLKND KLESVEPQRQ IIQEEEREKG SVALDVYWKY ITLAYGGALV
960 970 980 990 1000
PFILLGQVLF QLLQIGSNYW MAWATPVSED VQAPVKLSTL MIVYVALAFG
1010 1020 1030 1040 1050
SSLCILLRAT LLVTAGYKTA TELFHKMHHC IFRSPMSFFD STPSGRIMSR
1060 1070 1080 1090 1100
ASTDQSAVDL ELPYQFGSVA ITVIQLIGII GVMSQVSWLV FLVFIPVVAA
1110 1120 1130 1140 1150
SIWYQRYYIA AARELSRLVG VCKAPLIQHF SETISGATTI RSFSQEFRFR
1160 1170 1180 1190 1200
SDNMRLSDGY SRPKFYTAGA MEWLCFRLDM LSSLTFVFSL VFLVSIPTGV
1210 1220 1230 1240 1250
IDPSLAGLAV TYGLSLNTLQ AWLIWTLCNL ENKIISVERI LQYASVPSEP
1260 1270 1280 1290 1300
PLVIESNRPE QSWPSRGEVE IRDLQVRYAP HMPLVLRGIT CTFKGGLRTG
1310 1320 1330 1340 1350
IVGRTGSGKS TLIQTLFRIV EPSAGEIRID GVNILTIGLH DLRLRLSIIP
1360 1370 1380 1390 1400
QDPTMFEGTM RSNLDPLEEY TDDQIWEALD KCQLGDEVRK KEQKLDSSVS
1410 1420 1430 1440 1450
ENGDNWSMGQ RQLVCLGRVL LKRSKILVLD EATASVDTAT DNLIQKTLRE
1460 1470 1480 1490 1500
HFSDCTVITI AHRISSVIDS DMVLLLSNGI IEEYDTPVRL LEDKSSSFSK
1510
LVAEYTSRSS SSFD
Length:1,514
Mass (Da):168,971
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i455575FCD3DA5115
GO
Isoform 2 (identifier: Q9LK64-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1347-1372: SIIPQDPTMFEGTMRSNLDPLEEYTD → N

Show »
Length:1,489
Mass (Da):166,103
Checksum:i217F67BF2FBC405D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1I9LTU2A0A1I9LTU2_ARATH
ABC-type xenobiotic transporter
ABCC3 ATMRP3, ATP-binding cassette C3, MJG19.26, MJG19_26, MULTIDRUG RESISTANCE PROTEIN 3
1,510Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F4JB38F4JB38_ARATH
Multidrug resistance-associated pro...
ABCC3 ATMRP3, ATP-binding cassette C3, MJG19.26, MJG19_26, MULTIDRUG RESISTANCE PROTEIN 3
1,120Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC49791 differs from that shown. Reason: Frameshift.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0180991347 – 1372SIIPQ…EEYTD → N in isoform 2. CuratedAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U92650 mRNA Translation: AAC49791.1 Frameshift.
AP000375 Genomic DNA Translation: BAB01399.1
CP002686 Genomic DNA Translation: AEE75291.1
CP002686 Genomic DNA Translation: AEE75292.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T52081

NCBI Reference Sequences

More...
RefSeqi
NP_187915.1, NM_112147.3 [Q9LK64-1]
NP_850575.1, NM_180244.1 [Q9LK64-2]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G13080.1; AT3G13080.1; AT3G13080 [Q9LK64-1]
AT3G13080.2; AT3G13080.2; AT3G13080 [Q9LK64-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
820496

Gramene; a comparative resource for plants

More...
Gramenei
AT3G13080.1; AT3G13080.1; AT3G13080 [Q9LK64-1]
AT3G13080.2; AT3G13080.2; AT3G13080 [Q9LK64-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G13080

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U92650 mRNA Translation: AAC49791.1 Frameshift.
AP000375 Genomic DNA Translation: BAB01399.1
CP002686 Genomic DNA Translation: AEE75291.1
CP002686 Genomic DNA Translation: AEE75292.1
PIRiT52081
RefSeqiNP_187915.1, NM_112147.3 [Q9LK64-1]
NP_850575.1, NM_180244.1 [Q9LK64-2]

3D structure databases

SMRiQ9LK64
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G13080.1

Protein family/group databases

TCDBi3.A.1.208.17, the atp-binding cassette (abc) superfamily

Proteomic databases

PaxDbiQ9LK64
PRIDEiQ9LK64
ProteomicsDBi244605 [Q9LK64-1]

Genome annotation databases

EnsemblPlantsiAT3G13080.1; AT3G13080.1; AT3G13080 [Q9LK64-1]
AT3G13080.2; AT3G13080.2; AT3G13080 [Q9LK64-2]
GeneIDi820496
GrameneiAT3G13080.1; AT3G13080.1; AT3G13080 [Q9LK64-1]
AT3G13080.2; AT3G13080.2; AT3G13080 [Q9LK64-2]
KEGGiath:AT3G13080

Organism-specific databases

AraportiAT3G13080
TAIRilocus:2090029, AT3G13080

Phylogenomic databases

eggNOGiKOG0054, Eukaryota
HOGENOMiCLU_000604_27_3_1
InParanoidiQ9LK64
OMAiLDYECSE
PhylomeDBiQ9LK64

Enzyme and pathway databases

BioCyciARA:AT3G13080-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9LK64

Gene expression databases

ExpressionAtlasiQ9LK64, baseline and differential
GenevisibleiQ9LK64, AT

Family and domain databases

CDDicd18579, ABC_6TM_ABCC_D1, 1 hit
cd18580, ABC_6TM_ABCC_D2, 1 hit
Gene3Di1.20.1560.10, 2 hits
3.40.50.300, 2 hits
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR011527, ABC1_TM_dom
IPR036640, ABC1_TM_sf
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR044746, ABCC_6TM_D1
IPR044726, ABCC_6TM_D2
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00664, ABC_membrane, 2 hits
PF00005, ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
SSF90123, SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929, ABC_TM1F, 2 hits
PS00211, ABC_TRANSPORTER_1, 1 hit
PS50893, ABC_TRANSPORTER_2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAB3C_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9LK64
Secondary accession number(s): O24510, Q3EB73
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: October 1, 2000
Last modified: September 29, 2021
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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