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UniProtKB - Q9LDK9 (APBLA_ARATH)

Entry version 116 (12 Aug 2020)
Sequence version 1 (01 Oct 2000)
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Protein

Beta-adaptin-like protein A

Gene

BETAA-AD

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Beta-adaptin-like protein A
Short name:
At-bA-Ad
Short name:
At-betaA-Ad
Alternative name(s):
AP complex subunit beta-A
Adaptor protein complex AP subunit beta-A
Beta-adaptin A
Clathrin assembly protein complex beta large chain A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BETAA-AD
Ordered Locus Names:At5g11490
ORF Names:F15N18.80
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT5G11490

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicle, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003978481 – 841Beta-adaptin-like protein AAdd BLAST841

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9LDK9

PRoteomics IDEntifications database

More...PRIDEi		Q9LDK9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		244423 [Q9LDK9-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9LDK9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9LDK9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9LDK9, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Adaptor protein complexes are heterotetramers composed of two large adaptins (beta-type subunit and alpha-type or delta-type or epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit) (By similarity).

Interacts with AHK2.

By similarity1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		16299, 2 interactors

Protein interaction database and analysis system

More...IntActi		Q9LDK9, 1 interactor

STRING: functional protein association networks

More...STRINGi		3702.AT5G11490.2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the adaptor complexes large subunit family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1061, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_006320_4_5_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9LDK9

Identification of Orthologs from Complete Genome Data

More...OMAi		ESLIENW

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9LDK9

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 1 hit
3.30.310.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026739, AP_beta
IPR016342, AP_complex_bsu_1_2_4
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR015151, B-adaptin_app_sub_C
IPR002553, Clathrin/coatomer_adapt-like_N
IPR012295, TBP_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR11134, PTHR11134, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01602, Adaptin_N, 1 hit
PF09066, B2-adapt-app_C, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002291, AP_complex_beta, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01020, B2-adapt-app_C, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9LDK9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAPPAASQRY PSPSQPSGKS EVSDLKTQLR QLAGSRAPGV DDSKRDLYKK 
        60         70         80         90        100
VISYMTIGID VSSVFGEMVM CSATSDIVLK KMCYLYVGNY AKGNPDLSLL 
       110        120        130        140        150
TINFLQRDCK DEDPMIRGLA LRSLCSLRVP NLVEYLVGPL GSGLKDNNSY 
       160        170        180        190        200
VRTIAVTGVL KLYHISPSTC IDADFPATLK SLMLHDSDAQ VVANCLSALQ 
       210        220        230        240        250
EIWSLEASHS EEACREKESL LSKPVIYYFL NRIKEFNEWA QCLILELAVK 
       260        270        280        290        300
YVPSDSNDIF DIMNLLEDRL QHANGAVVLA TVKVFLQLTL SMTDVHQQVY 
       310        320        330        340        350
ERIKSPLLTL VSSGSPEQSY AILSHLHLLV VRAPFIFAAD YKHFYCQYNE 
       360        370        380        390        400
PSYVKKLKLE MLTAVANESN TYEIVTELCE YAANVDIAIA RESIRAVGKI 
       410        420        430        440        450
ALQQYDVNAI VDRLLQFLEM EKDYVTAETL VLVKDLLRKY PQWSHDCISV 
       460        470        480        490        500
VGGISSKNIQ EPKAKAALIW MLGEYAQDMS DAPYVLENLI ENWEEEHSAE 
       510        520        530        540        550
VRLHLLTAAM KCFFKRAPET QKALGTALAA GIADFHQDVH DRALFYYRVL 
       560        570        580        590        600
QYDVHVAERV VSPPKQAVSV FADTQSSEIK DRVFDEFNSL SVIYQKPSYM 
       610        620        630        640        650
FTDKEHRGPF EFSDEVGNIS ITPEASSDIV PAQQYEANDK DLLLGIDEKD 
       660        670        680        690        700
ENKGVSNNNG SAYTAPSLES SSNITSQMQE LAISGPATSA TTPQSFGFDD 
       710        720        730        740        750
LFGLGLSTAP APTPSPPLLK LNARAALDPG AFQQKWRQLP ISLTQECSVN 
       760        770        780        790        800
PQGIAALTVP QSLIKHMQSH SIHCIASGGQ SPNFKFFFFA QKESEPSNYL 
       810        820        830        840 
TECIINTSSA KAQIKVKADE QSTCQAFTTV FETALSKFGM P
Length:841
Mass (Da):93,266
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i89906E3AB705711C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4JXV9F4JXV9_ARATH
Beta-adaptin-like protein
At5g11490
850Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BB38A0A1P8BB38_ARATH
Beta-adaptin-like protein
At5g11490
796Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF216385 mRNA Translation: AAF61671.1
AL163815 Genomic DNA Translation: CAB87709.1
CP002688 Genomic DNA Translation: AED91685.1

Protein sequence database of the Protein Information Resource

More...PIRi		T48508

NCBI Reference Sequences

More...RefSeqi		NP_196710.1, NM_121187.4 [Q9LDK9-1]

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT5G11490.1; AT5G11490.1; AT5G11490 [Q9LDK9-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		831021

Gramene; a comparative resource for plants

More...Gramenei		AT5G11490.1; AT5G11490.1; AT5G11490 [Q9LDK9-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT5G11490

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF216385 mRNA Translation: AAF61671.1
AL163815 Genomic DNA Translation: CAB87709.1
CP002688 Genomic DNA Translation: AED91685.1
PIRiT48508
RefSeqiNP_196710.1, NM_121187.4 [Q9LDK9-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi16299, 2 interactors
IntActiQ9LDK9, 1 interactor
STRINGi3702.AT5G11490.2

PTM databases

iPTMnetiQ9LDK9

Proteomic databases

PaxDbiQ9LDK9
PRIDEiQ9LDK9
ProteomicsDBi244423 [Q9LDK9-1]

Genome annotation databases

EnsemblPlantsiAT5G11490.1; AT5G11490.1; AT5G11490 [Q9LDK9-1]
GeneIDi831021
GrameneiAT5G11490.1; AT5G11490.1; AT5G11490 [Q9LDK9-1]
KEGGiath:AT5G11490

Organism-specific databases

AraportiAT5G11490

Phylogenomic databases

eggNOGiKOG1061, Eukaryota
HOGENOMiCLU_006320_4_5_1
InParanoidiQ9LDK9
OMAiESLIENW
PhylomeDBiQ9LDK9

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9LDK9

Gene expression databases

ExpressionAtlasiQ9LDK9, baseline and differential
GenevisibleiQ9LDK9, AT

Family and domain databases

Gene3Di1.25.10.10, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR026739, AP_beta
IPR016342, AP_complex_bsu_1_2_4
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR015151, B-adaptin_app_sub_C
IPR002553, Clathrin/coatomer_adapt-like_N
IPR012295, TBP_dom_sf
PANTHERiPTHR11134, PTHR11134, 1 hit
PfamiView protein in Pfam
PF01602, Adaptin_N, 1 hit
PF09066, B2-adapt-app_C, 1 hit
PIRSFiPIRSF002291, AP_complex_beta, 1 hit
SMARTiView protein in SMART
SM01020, B2-adapt-app_C, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAPBLA_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9LDK9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: October 1, 2000
Last modified: August 12, 2020
This is version 116 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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