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UniProtKB - Q9LDF2 (LOH1_ARATH)

Entry version 127 (23 Feb 2022)
Sequence version 1 (01 Oct 2000)
Previous versions | rss
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Protein

Ceramide synthase LOH1

Gene

LOH1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential for plant growth, promotes cell division in root meristems (PubMed:21666002, PubMed:21883234, PubMed:26276842).

Catalyzes the biosynthesis of ceramide sphingolipids with C(16) to C(28) fatty acids, structural membrane lipids involved in membrane trafficking (e.g. early endosomes) and cell polarity (e.g. polar auxin transport related proteins); mostly active with t18:0 and saturated very long saturated fatty acids (C24:0 and C26:0), such as long-chain base (LCB) phytosphingosine (t18:0), lignoceroyl- and hexacosanoyl-CoAs (PubMed:21883234, PubMed:26635357, PubMed:21666002, PubMed:26276842).

Mediates resistance to sphinganine-analog mycotoxins (SAMs, e.g. fumonisin B1) by restoring the sphingolipid biosynthesis (By similarity).

Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity).

May prevent precocious cell death by delaying PR1 accumulation during aging (PubMed:21883234).

Contributes to hypoxic conditions tolerance (e.g. submergences), especially in the dark, by promoting the formation of very-long-chain (VLC) ceramide species (22:1, 24:1 and 26:1) and of VLC unsaturated ceramides, which are modulating CTR1-mediated ethylene signaling leading to endoplasmic reticulum (ER)-to-nucleus translocation of EIN2 and EIN3 (PubMed:25822663).

By similarity5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by the mycotoxin fumonisin B1, a sphingosine analog mycotoxins produced by pathogenic fungi (PubMed:26276842, PubMed:26635357). Repressed by divalent cation such as magnesium Mg2+, copper Cu2+, zinc Zn2+, manganese Mn2+, calcium Ca2+ and cobalt Co2+ (PubMed:26635357).2 Publications

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=6.9 µM for phytosphingosine (t18:0)1 Publication
  1. Vmax=273 pmol/min/mg enzyme with phytosphingosine (t18:0) as substrate1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: Sphingolipid metabolism

This protein is involved in Sphingolipid metabolism.3 Publications
View all proteins of this organism that are known to be involved in Sphingolipid metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processLipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.3.1.297, 399

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ceramide synthase LOH11 Publication (EC:2.3.1.-3 Publications)
Short name:
Short name:
CSII1 Publication
Alternative name(s):
Protein LONGEVITY ASSURANCE GENE ONE HOMOLOG 11 Publication
Short name:
LAG One Homolog 11 Publication
Short name:
LAG1 homolog 11 Publication
Short name:
LAG1 longevity assurance homolog 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOH12 Publications
Synonyms:LAG11 Publication
Ordered Locus Names:At3g25540Imported
ORF Names:MWL2.19Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT3G25540

The Arabidopsis Information Resource

More...TAIRi		locus:2094528, AT3G25540

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei16 – 36HelicalSequence analysisAdd BLAST21
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Transmembranei216 – 236HelicalSequence analysisAdd BLAST21
Transmembranei260 – 280HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Elevated levels of free trihydroxy sphingoid bases as well as ceramide and glucosylceramide species with C(16) fatty acid, but reduced levels of species with C(20) to C(28) fatty acids (PubMed:21883234, PubMed:25822663). Spontaneous cell death accompanied by an enhanced PR1 expression at advanced age (PubMed:21883234). The double mutant loh1 loh3 is embryonically lethal (PubMed:21883234, PubMed:21666002). Rare viable loh1 loh3 seedlings have a complete absence of very-long-chain fatty acid (VLCFA) in sphingolipids and exhibit strong dwarf phenotype and altered lateral root outgrowth associated with disrupted early endosomes and an impaired polar auxin transport due to abnormal localization of auxin transporters in the plasma membrane; these phenotypes are in part restored by external auxin (NAA) (PubMed:21666002). Better resistance to submergence under light conditions, but increased sensitivity to dark submergence associated with declined levels of unsaturated very-long-chain (VLC) ceramide species (22:1, 24:1 and 26:1) (PubMed:25822663). The double mutant loh1 loh3, lacking (VLC), have an impaired tolerance to both dark and light submergences (PubMed:25822663).3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001855181 – 310Ceramide synthase LOH1Add BLAST310

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei300PhosphoserineBy similarity1
Modified residuei302PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9LDF2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		237069

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9LDF2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed ubiquitously at high levels (PubMed:21883234). Not observed in pollen (PubMed:25794895).2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9LDF2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9LDF2, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		3702.AT3G25540.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9LDF2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini76 – 289TLCPROSITE-ProRule annotationAdd BLAST214

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1607, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_028277_5_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9LDF2

Identification of Orthologs from Complete Genome Data

More...OMAi		WEDFPKM

Database of Orthologous Groups

More...OrthoDBi		987268at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9LDF2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016439, Lag1/Lac1-like
IPR006634, TLC-dom

The PANTHER Classification System

More...PANTHERi		PTHR12560, PTHR12560, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03798, TRAM_LAG1_CLN8, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF005225, LAG1_LAC1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00724, TLC, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50922, TLC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9LDF2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLFESVKSI DWEQESFPTY QDLGFLPLFA VFFPTIRFLL DRFVFEKLAS 
        60         70         80         90        100
LVIYGRMSTN KSDNIKDRKK NSPKVRKFKE SAWKCIYYLS AELLALSVTY 
       110        120        130        140        150
NEPWFSNTLY FWIGPGDQIW PDQPMKMKLK FLYMFAAGFY TYSIFALVFW 
       160        170        180        190        200
ETRRSDFGVS MGHHITTLVL IVLSYICRLT RAGSVILALH DASDVFLEIG 
       210        220        230        240        250
KMSKYCGAES LASISFVLFA LSWVVLRLIY YPFWILWSTS YQIIMTVDKE 
       260        270        280        290        300
KHPNGPILYY MFNTLLYFLL VLHIFWWVLI YRMLVKQVQD RGKLSEDVRS 
       310
DSESDDEHED
Length:310
Mass (Da):36,498
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB3E1F2D5D3A4AEAD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1I9LTU4A0A1I9LTU4_ARATH
TRAM, LAG1 and CLN8 (TLC) lipid-sen...
LAG1 LAG One Homologue 1, LAG1 HOMOLOG 1, LOH1, LONGEVITY ASSURANCE GENE 1, At3g25540
242Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF198179 mRNA Translation: AAF66102.1
AB025639 Genomic DNA Translation: BAB01323.1
CP002686 Genomic DNA Translation: AEE77023.1
CP002686 Genomic DNA Translation: ANM66003.1
AF360152 mRNA Translation: AAK25862.1
AY142597 mRNA Translation: AAN13166.1

NCBI Reference Sequences

More...RefSeqi		NP_001319643.1, NM_001338755.1
NP_566769.1, NM_113450.5

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT3G25540.1; AT3G25540.1; AT3G25540
AT3G25540.3; AT3G25540.3; AT3G25540

Database of genes from NCBI RefSeq genomes

More...GeneIDi		822140

Gramene; a comparative resource for plants

More...Gramenei		AT3G25540.1; AT3G25540.1; AT3G25540
AT3G25540.3; AT3G25540.3; AT3G25540

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT3G25540

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF198179 mRNA Translation: AAF66102.1
AB025639 Genomic DNA Translation: BAB01323.1
CP002686 Genomic DNA Translation: AEE77023.1
CP002686 Genomic DNA Translation: ANM66003.1
AF360152 mRNA Translation: AAK25862.1
AY142597 mRNA Translation: AAN13166.1
RefSeqiNP_001319643.1, NM_001338755.1
NP_566769.1, NM_113450.5

3D structure databases

SMRiQ9LDF2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G25540.1

PTM databases

iPTMnetiQ9LDF2

Proteomic databases

PaxDbiQ9LDF2
ProteomicsDBi237069

Genome annotation databases

EnsemblPlantsiAT3G25540.1; AT3G25540.1; AT3G25540
AT3G25540.3; AT3G25540.3; AT3G25540
GeneIDi822140
GrameneiAT3G25540.1; AT3G25540.1; AT3G25540
AT3G25540.3; AT3G25540.3; AT3G25540
KEGGiath:AT3G25540

Organism-specific databases

AraportiAT3G25540
TAIRilocus:2094528, AT3G25540

Phylogenomic databases

eggNOGiKOG1607, Eukaryota
HOGENOMiCLU_028277_5_0_1
InParanoidiQ9LDF2
OMAiWEDFPKM
OrthoDBi987268at2759
PhylomeDBiQ9LDF2

Enzyme and pathway databases

BRENDAi2.3.1.297, 399

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9LDF2

Gene expression databases

ExpressionAtlasiQ9LDF2, baseline and differential
GenevisibleiQ9LDF2, AT

Family and domain databases

InterProiView protein in InterPro
IPR016439, Lag1/Lac1-like
IPR006634, TLC-dom
PANTHERiPTHR12560, PTHR12560, 1 hit
PfamiView protein in Pfam
PF03798, TRAM_LAG1_CLN8, 1 hit
PIRSFiPIRSF005225, LAG1_LAC1, 1 hit
SMARTiView protein in SMART
SM00724, TLC, 1 hit
PROSITEiView protein in PROSITE
PS50922, TLC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLOH1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9LDF2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 1, 2000
Last modified: February 23, 2022
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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