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Entry version 126 (07 Apr 2021)
Sequence version 2 (21 Nov 2003)
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Protein

Potassium transporter 4

Gene

POT4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

High-affinity potassium transporter.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Potassium transport, Transport
LigandPotassium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Potassium transporter 4
Short name:
AtKT4
Short name:
AtKUP3
Short name:
AtPOT4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POT4
Synonyms:KT4, KUP3
Ordered Locus Names:At3g02050
ORF Names:F1C9.17
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G02050

The Arabidopsis Information Resource

More...
TAIRi
locus:2078688, AT3G02050

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 32CytoplasmicSequence analysisAdd BLAST32
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Topological domaini54 – 68ExtracellularSequence analysisAdd BLAST15
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Topological domaini90 – 154CytoplasmicSequence analysisAdd BLAST65
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Topological domaini176 – 195ExtracellularSequence analysisAdd BLAST20
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Topological domaini217 – 219CytoplasmicSequence analysis3
Transmembranei220 – 240HelicalSequence analysisAdd BLAST21
Topological domaini241 – 270ExtracellularSequence analysisAdd BLAST30
Transmembranei271 – 291HelicalSequence analysisAdd BLAST21
Topological domaini292 – 300CytoplasmicSequence analysis9
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21
Topological domaini322 – 340ExtracellularSequence analysisAdd BLAST19
Transmembranei341 – 361HelicalSequence analysisAdd BLAST21
Topological domaini362 – 392CytoplasmicSequence analysisAdd BLAST31
Transmembranei393 – 413HelicalSequence analysisAdd BLAST21
Topological domaini414 – 424ExtracellularSequence analysisAdd BLAST11
Transmembranei425 – 445HelicalSequence analysisAdd BLAST21
Topological domaini446 – 450CytoplasmicSequence analysis5
Transmembranei451 – 471HelicalSequence analysisAdd BLAST21
Topological domaini472 – 478ExtracellularSequence analysis7
Transmembranei479 – 499HelicalSequence analysisAdd BLAST21
Topological domaini500 – 789CytoplasmicSequence analysisAdd BLAST290

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002090801 – 789Potassium transporter 4Add BLAST789

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei9PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9LD18

PRoteomics IDEntifications database

More...
PRIDEi
Q9LD18

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
250606

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9LD18

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected at very low levels in roots, stems, leaves and flowers of mature plants and strongly expressed in the roots of potassium-starved plants.1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By potassium starvation.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9LD18, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9LD18, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT3G02050.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QPSA, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008142_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9LD18

Identification of Orthologs from Complete Genome Data

More...
OMAi
YMPLANW

Database of Orthologous Groups

More...
OrthoDBi
332035at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9LD18

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003855, K+_transporter

The PANTHER Classification System

More...
PANTHERi
PTHR30540, PTHR30540, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02705, K_trans, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00794, kup, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9LD18-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPAESGVSP RRNPSQLSWM NLSSNLILAY QSFGVVYGDL STSPLYVFPS
60 70 80 90 100
TFIGKLHKHH NEDAVFGAFS LIFWTLTLIP LLKYLLVLLS ADDNGEGGTF
110 120 130 140 150
ALYSLLCRHA KLSLLPNQQA ADEELSAYKF GPSTDTVTSS PFRTFLEKHK
160 170 180 190 200
RLRTALLLVV LFGAAMVIGD GVLTPALSVL SSLSGLQATE KNVTDGELLV
210 220 230 240 250
LACVILVGLF ALQHCGTHRV AFMFAPIVII WLISIFFIGL YNIIRWNPKI
260 270 280 290 300
IHAVSPLYII KFFRVTGQDG WISLGGVLLS VTGTEAMFAN LGHFTSVSIR
310 320 330 340 350
VAFAVVVYPC LVVQYMGQAA FLSKNLGSIP NSFYDSVPDP VFWPVFVIAT
360 370 380 390 400
LAAIVGSQAV ITTTFSIIKQ CHALGCFPRI KVVHTSKHIY GQIYIPEINW
410 420 430 440 450
ILMILTLAMA IGFRDTTLIG NAYGIACMVV MFITTFFMAL VIVVVWQKSC
460 470 480 490 500
FLAALFLGTL WIIEGVYLSA ALMKVTEGGW VPFVLTFIFM IAMYVWHYGT
510 520 530 540 550
RRKYSFDLHN KVSLKWLLGL GPSLGIVRVP GIGLVYSELA TGVPAIFSHF
560 570 580 590 600
VTNLPAFHKV VVFVCVKSVP VPHVSPEERF LIGRVCPKPY RMYRCIVRYG
610 620 630 640 650
YKDIQREDGD FENQLVQSIA EFIQMEASDL QSSASESQSN DGRMAVLSSQ
660 670 680 690 700
KSLSNSILTV SEVEEIDYAD PTIQSSKSMT LQSLRSVYED EYPQGQVRRR
710 720 730 740 750
HVRFQLTASS GGMGSSVREE LMDLIRAKEA GVAYIMGHSY VKSRKSSSWL
760 770 780
KKMAIDIGYS FLRKNCRGPA VALNIPHISL IEVGMIYYV
Length:789
Mass (Da):87,411
Last modified:November 21, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i07A0E89CA81B8B31
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti573 – 574HV → SLF in AAF19432 (PubMed:9477571).Curated2
Sequence conflicti723 – 726DLIR → GSDT in AAF19432 (PubMed:9477571).Curated4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF207621 mRNA Translation: AAF19432.2
AC011664 Genomic DNA Translation: AAF14830.1
CP002686 Genomic DNA Translation: AEE73753.1
AY062747 mRNA Translation: AAL32825.1
BT003375 mRNA Translation: AAO30038.1
AF012659 mRNA Translation: AAC49847.1

NCBI Reference Sequences

More...
RefSeqi
NP_186854.1, NM_111071.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G02050.1; AT3G02050.1; AT3G02050

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
821063

Gramene; a comparative resource for plants

More...
Gramenei
AT3G02050.1; AT3G02050.1; AT3G02050

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G02050

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF207621 mRNA Translation: AAF19432.2
AC011664 Genomic DNA Translation: AAF14830.1
CP002686 Genomic DNA Translation: AEE73753.1
AY062747 mRNA Translation: AAL32825.1
BT003375 mRNA Translation: AAO30038.1
AF012659 mRNA Translation: AAC49847.1
RefSeqiNP_186854.1, NM_111071.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi3702.AT3G02050.1

PTM databases

iPTMnetiQ9LD18

Proteomic databases

PaxDbiQ9LD18
PRIDEiQ9LD18
ProteomicsDBi250606

Genome annotation databases

EnsemblPlantsiAT3G02050.1; AT3G02050.1; AT3G02050
GeneIDi821063
GrameneiAT3G02050.1; AT3G02050.1; AT3G02050
KEGGiath:AT3G02050

Organism-specific databases

AraportiAT3G02050
TAIRilocus:2078688, AT3G02050

Phylogenomic databases

eggNOGiENOG502QPSA, Eukaryota
HOGENOMiCLU_008142_2_0_1
InParanoidiQ9LD18
OMAiYMPLANW
OrthoDBi332035at2759
PhylomeDBiQ9LD18

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9LD18

Gene expression databases

ExpressionAtlasiQ9LD18, baseline and differential
GenevisibleiQ9LD18, AT

Family and domain databases

InterProiView protein in InterPro
IPR003855, K+_transporter
PANTHERiPTHR30540, PTHR30540, 1 hit
PfamiView protein in Pfam
PF02705, K_trans, 1 hit
TIGRFAMsiTIGR00794, kup, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOT4_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9LD18
Secondary accession number(s): O22400, Q9SGA3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: November 21, 2003
Last modified: April 7, 2021
This is version 126 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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