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UniProtKB - Q9KTA6 (SYQ_VIBCH)
Protein
Glutamine--tRNA ligase
Gene
glnS
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Status
Functioni
Catalytic activityi
- EC:6.1.1.18UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 67 | L-glutamineUniRule annotation | 1 | |
Binding sitei | 212 | L-glutamineUniRule annotation | 1 | |
Binding sitei | 231 | ATPUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 35 – 37 | ATPUniRule annotation | 3 | |
Nucleotide bindingi | 41 – 47 | ATPUniRule annotation | 7 | |
Nucleotide bindingi | 261 – 262 | ATPUniRule annotation | 2 | |
Nucleotide bindingi | 269 – 271 | ATPUniRule annotation | 3 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- glutamine-tRNA ligase activity Source: GO_Central
GO - Biological processi
- glutaminyl-tRNA aminoacylation Source: GO_Central
- glutamyl-tRNA aminoacylation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)Alternative name(s): Glutaminyl-tRNA synthetaseUniRule annotation Short name: GlnRSUniRule annotation |
Gene namesi | Name:glnSUniRule annotation Ordered Locus Names:VC_0997 |
Organismi | Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) |
Taxonomic identifieri | 243277 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Cytosol
- cytosol Source: GO_Central
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000195852 | 1 – 556 | Glutamine--tRNA ligaseAdd BLAST | 556 |
Interactioni
Subunit structurei
Monomer.
UniRule annotationProtein-protein interaction databases
STRINGi | 243277.VC_0997 |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 34 – 44 | 'HIGH' regionUniRule annotationAdd BLAST | 11 | |
Motifi | 268 – 272 | 'KMSKS' regionUniRule annotation | 5 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0008, Bacteria |
HOGENOMi | CLU_001882_2_3_6 |
OMAi | INNFCAQ |
Family and domain databases
Gene3Di | 1.10.1160.10, 1 hit 2.40.240.10, 2 hits 3.40.50.620, 1 hit |
HAMAPi | MF_00126, Gln_tRNA_synth, 1 hit |
InterProi | View protein in InterPro IPR001412, aa-tRNA-synth_I_CS IPR004514, Gln-tRNA-synth IPR022861, Gln_tRNA_ligase_bac IPR000924, Glu/Gln-tRNA-synth IPR020058, Glu/Gln-tRNA-synth_Ib_cat-dom IPR020059, Glu/Gln-tRNA-synth_Ib_codon-bd IPR020061, Glu_tRNA_lig_a-bdl IPR020056, Rbsml_L25/Gln-tRNA_synth_N IPR011035, Ribosomal_L25/Gln-tRNA_synth IPR014729, Rossmann-like_a/b/a_fold |
Pfami | View protein in Pfam PF00749, tRNA-synt_1c, 1 hit PF03950, tRNA-synt_1c_C, 1 hit |
PRINTSi | PR00987, TRNASYNTHGLU |
SUPFAMi | SSF50715, SSF50715, 1 hit |
TIGRFAMsi | TIGR00440, glnS, 1 hit |
PROSITEi | View protein in PROSITE PS00178, AA_TRNA_LIGASE_I, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9KTA6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEAEARPSN FIRQIIDKDL ADGKHTTVHT RFPPEPNGYL HIGHAKSICL
60 70 80 90 100
NFGIAQDYQG QCNLRFDDTN PEKENLEYVE SIKKDVTWLG FDWSGEVCYS
110 120 130 140 150
SDYFDKLYEY AIELIQKGLA YVDELTPEQI REYRGTLTEP GKHSPYRDRS
160 170 180 190 200
VEENLALFEK MRAGEFAEGQ ACLRAKIDMA SSFIVMRDPV LYRVRFAEHH
210 220 230 240 250
QTGDKWCIYP MYDFTHCISD ALEGITHSIC TLEFQDNRRL YDWVLDNITI
260 270 280 290 300
PCHPRQYEFS RLNLEYTVMS KRKLNQLVTE KLVTGWDDPR MPTISGLRRR
310 320 330 340 350
GFTPSAIREF CKRIGVTKQE NMIEYSALES CIRDDLNENA PRAMAVLDPV
360 370 380 390 400
KLVIENFAAG TVETLTLANH PNKPEMGDRE VPFTRELWIE REDFREEANK
410 420 430 440 450
KYKRLVLGKE VRLRGAYVIK AERIEKDEQG NITTIFCSYD PETLGKNPAD
460 470 480 490 500
GRKVKGVIHW VSAEKGVPAE FRLYERLFTV PNPGAADNFA ETINPESLVK
510 520 530 540 550
VQGYVEPSLV EAKPEFGYQF ERMGYFCADN KDSSPQALVF NRTVGLRDSF
AKIDEE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE003852 Genomic DNA Translation: AAF94158.1 |
PIRi | H82254 PC4398 |
RefSeqi | NP_230643.1, NC_002505.1 WP_001287115.1, NZ_LT906614.1 |
Genome annotation databases
EnsemblBacteriai | AAF94158; AAF94158; VC_0997 |
GeneIDi | 57739682 |
KEGGi | vch:VC0997 |
PATRICi | fig|243277.26.peg.950 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE003852 Genomic DNA Translation: AAF94158.1 |
PIRi | H82254 PC4398 |
RefSeqi | NP_230643.1, NC_002505.1 WP_001287115.1, NZ_LT906614.1 |
3D structure databases
SMRi | Q9KTA6 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 243277.VC_0997 |
Protocols and materials databases
DNASUi | 2614250 |
Genome annotation databases
EnsemblBacteriai | AAF94158; AAF94158; VC_0997 |
GeneIDi | 57739682 |
KEGGi | vch:VC0997 |
PATRICi | fig|243277.26.peg.950 |
Phylogenomic databases
eggNOGi | COG0008, Bacteria |
HOGENOMi | CLU_001882_2_3_6 |
OMAi | INNFCAQ |
Family and domain databases
Gene3Di | 1.10.1160.10, 1 hit 2.40.240.10, 2 hits 3.40.50.620, 1 hit |
HAMAPi | MF_00126, Gln_tRNA_synth, 1 hit |
InterProi | View protein in InterPro IPR001412, aa-tRNA-synth_I_CS IPR004514, Gln-tRNA-synth IPR022861, Gln_tRNA_ligase_bac IPR000924, Glu/Gln-tRNA-synth IPR020058, Glu/Gln-tRNA-synth_Ib_cat-dom IPR020059, Glu/Gln-tRNA-synth_Ib_codon-bd IPR020061, Glu_tRNA_lig_a-bdl IPR020056, Rbsml_L25/Gln-tRNA_synth_N IPR011035, Ribosomal_L25/Gln-tRNA_synth IPR014729, Rossmann-like_a/b/a_fold |
Pfami | View protein in Pfam PF00749, tRNA-synt_1c, 1 hit PF03950, tRNA-synt_1c_C, 1 hit |
PRINTSi | PR00987, TRNASYNTHGLU |
SUPFAMi | SSF50715, SSF50715, 1 hit |
TIGRFAMsi | TIGR00440, glnS, 1 hit |
PROSITEi | View protein in PROSITE PS00178, AA_TRNA_LIGASE_I, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SYQ_VIBCH | |
Accessioni | Q9KTA6Primary (citable) accession number: Q9KTA6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 2000 |
Last sequence update: | October 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 123 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Aminoacyl-tRNA synthetases
List of aminoacyl-tRNA synthetase entries - SIMILARITY comments
Index of protein domains and families