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UniProtKB - Q9KJE9 (BBSF_THAAR)
Protein
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase subunit BbsF
Gene
bbsF
Organism
Thauera aromatica
Status
Functioni
Catalyzes the reversible conversion of (R)-2-benzylsuccinate to (R)-2-benzylsuccinyl-CoA. Inactive with (S)-benzylsuccinate.
1 PublicationCatalytic activityi
- EC:2.8.3.151 Publication
Activity regulationi
Inhibited by (S)-benzylsuccinyl-CoA.1 Publication
Kineticsi
- KM=40 µM for (R)-2-benzylsuccinyl-CoA1 Publication
- KM=160 µM for succinate1 Publication
: toluene degradation Pathwayi
This protein is involved in the pathway toluene degradation, which is part of Xenobiotic degradation.2 PublicationsView all proteins of this organism that are known to be involved in the pathway toluene degradation and in Xenobiotic degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 178 | NucleophileBy similarity | 1 |
GO - Molecular functioni
- succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity Source: UniProtKB-EC
GO - Biological processi
- toluene catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Transferase |
Biological process | Aromatic hydrocarbons catabolism |
Enzyme and pathway databases
SABIO-RKi | Q9KJE9 |
UniPathwayi | UPA00273 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:bbsF |
Organismi | Thauera aromatica |
Taxonomic identifieri | 59405 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Zoogloeaceae › Thauera |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed | |||
ChainiPRO_0000418887 | 2 – 409 | Succinyl-CoA:(R)-benzylsuccinate CoA-transferase subunit BbsFAdd BLAST | 408 |
Expressioni
Inductioni
Induced by toluene.1 Publication
Interactioni
Subunit structurei
Heterotetramer composed of 2 BbsE subunits and 2 BbsF subunits.
1 PublicationFamily & Domainsi
Sequence similaritiesi
Belongs to the CoA-transferase III family.Curated
Family and domain databases
Gene3Di | 3.30.1540.10, 1 hit 3.40.50.10540, 1 hit |
InterProi | View protein in InterPro IPR003673, CoA-Trfase_fam_III IPR044855, CoA-Trfase_III_dom3_sf IPR023606, CoA-Trfase_III_dom_1_sf |
Pfami | View protein in Pfam PF02515, CoA_transf_3, 1 hit |
SUPFAMi | SSF89796, SSF89796, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9KJE9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPNSIERALE GIVVCDFSWV GAGPIATSVL AQCGADVIKI ESVKRPDTLR
60 70 80 90 100
RGEPFKDGIG TGLDRSGYFA ARNANKRDIA LDMSHPRARE VAVRLIEKSD
110 120 130 140 150
IVINNFRVGQ MEKWKLGWED VQKINPRAIY VTMSMQGIDG PHSRYMGYGV
160 170 180 190 200
NLNALCGLTA RAGFPGQAPF GTGTNYTDHV MVPTHTLFGI MAALLEREAT
210 220 230 240 250
GRGQTVSLSQ LESAICMTPS APMAFAANGE ALGPQGYGDP EAAPHGVYTT
260 270 280 290 300
LGYRKWIAIA VFDDAQWATL RRVMGNPPWA EDERFATIEM RRRHAAELDE
310 320 330 340 350
RIEGWTATQY GDWLMEALLK AGVAAGEVRD AREAIEDEHL RRRGFWAYLD
360 370 380 390 400
HPEVGVTLYN RAPIVFSRTP VEMKSAAPSI GQHTREVLGG MLGYSHGEIE
DLAAQQVLV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF173961 Genomic DNA Translation: AAF89841.1 |
Genome annotation databases
KEGGi | ag:AAF89841 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF173961 Genomic DNA Translation: AAF89841.1 |
3D structure databases
AlphaFoldDBi | Q9KJE9 |
SMRi | Q9KJE9 |
ModBasei | Search... |
Genome annotation databases
KEGGi | ag:AAF89841 |
Enzyme and pathway databases
UniPathwayi | UPA00273 |
SABIO-RKi | Q9KJE9 |
Family and domain databases
Gene3Di | 3.30.1540.10, 1 hit 3.40.50.10540, 1 hit |
InterProi | View protein in InterPro IPR003673, CoA-Trfase_fam_III IPR044855, CoA-Trfase_III_dom3_sf IPR023606, CoA-Trfase_III_dom_1_sf |
Pfami | View protein in Pfam PF02515, CoA_transf_3, 1 hit |
SUPFAMi | SSF89796, SSF89796, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | BBSF_THAAR | |
Accessioni | Q9KJE9Primary (citable) accession number: Q9KJE9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 5, 2012 |
Last sequence update: | October 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families