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Entry version 173 (23 Feb 2022)
Sequence version 2 (06 Feb 2007)
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Protein

Unconventional myosin-XVIIIa

Gene

Myo18a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035).

Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (By similarity).

May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (PubMed:10733906).

Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346).

Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:21123169).

Strongly enhances natural killer cell cytotoxicity (By similarity).

By similarity4 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi498 – 505ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein, Myosin
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Unconventional myosin-XVIIIa
Alternative name(s):
Molecule associated with JAK3 N-terminus
Short name:
MAJN
Myosin containing a PDZ domain
Surfactant protein receptor SP-R2101 Publication
Short name:
SP-R2101 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Myo18a
Synonyms:Myspdz1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:2667185, Myo18a

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
HostDB:ENSMUSG00000000631

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Golgi apparatus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi503 – 504GK → SA: Loss of function. 1 Publication2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001234771 – 2050Unconventional myosin-XVIIIaAdd BLAST2050

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei35PhosphoserineBy similarity1
Modified residuei52PhosphoserineBy similarity1
Modified residuei72PhosphoserineCombined sources1
Modified residuei74PhosphoserineBy similarity1
Modified residuei79PhosphothreonineBy similarity1
Modified residuei83PhosphoserineCombined sources1
Modified residuei98PhosphoserineBy similarity1
Modified residuei99PhosphothreonineBy similarity1
Modified residuei102PhosphoserineCombined sources1
Modified residuei103PhosphoserineCombined sources1
Modified residuei140PhosphoserineBy similarity1
Modified residuei145PhosphoserineBy similarity1
Modified residuei157PhosphoserineCombined sources1
Modified residuei160PhosphoserineCombined sources1
Modified residuei164PhosphoserineCombined sources1
Modified residuei234PhosphoserineBy similarity1
Modified residuei983PhosphoserineCombined sources1
Modified residuei1063PhosphoserineBy similarity1
Modified residuei1064PhosphoserineBy similarity1
Modified residuei1066PhosphoserineBy similarity1
Modified residuei1636PhosphoserineBy similarity1
Modified residuei1938PhosphoserineBy similarity1
Modified residuei1966PhosphoserineCombined sources1
Modified residuei1970PhosphoserineBy similarity1
Modified residuei1994PhosphoserineCombined sources1
Modified residuei1998PhosphoserineBy similarity1
Modified residuei2002PhosphoserineBy similarity1
Modified residuei2003PhosphoserineBy similarity1
Modified residuei2016PhosphoserineCombined sources1
Modified residuei2032PhosphoserineCombined sources1
Modified residuei2037PhosphoserineCombined sources1
Modified residuei2039PhosphoserineCombined sources1
Modified residuei2041PhosphothreonineCombined sources1
Isoform 6 (identifier: Q9JMH9-6)
Modified residuei340PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated on tyrosine upon CSF1R activation. Isoform 6 is phosphorylated on Ser-340.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9JMH9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9JMH9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9JMH9

PeptideAtlas

More...
PeptideAtlasi
Q9JMH9

PRoteomics IDEntifications database

More...
PRIDEi
Q9JMH9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
252618 [Q9JMH9-3]
252619 [Q9JMH9-1]
252620 [Q9JMH9-2]
252621 [Q9JMH9-4]
252622 [Q9JMH9-5]
252623 [Q9JMH9-6]
252624 [Q9JMH9-7]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9JMH9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9JMH9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1; Expressed ubiquitously. Isoform 2: Specifically expressed in most hematopoietic cells. Isoform 3: Predominantly expressed in alveolar macrophages (PubMed:25965346).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000000631, Expressed in hindlimb stylopod muscle and 308 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9JMH9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9JMH9, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Forms a tripartite complex with CDC42BPA/CDC42BPB and LURAP1 with the latter acting as an adapter connecting CDC42BPA/CDC42BPB and MYO18A (By similarity). Binds F-actin; regulated by ADP and GOLPH3 (PubMed:15582604).

Interacts with GOLPH3; the interaction is direct and may link Golgi membranes to the actin cytoskeleton (By similarity).

Interacts with JAK3 (PubMed:10733938).

Interacts with MSR1 and CD14 (By similarity).

By similarity2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
237427, 14 interactors

Protein interaction database and analysis system

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IntActi
Q9JMH9, 4 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000130696

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9JMH9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9JMH9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini220 – 311PDZPROSITE-ProRule annotationAdd BLAST92
Domaini349 – 401Myosin N-terminal SH3-likePROSITE-ProRule annotationAdd BLAST53
Domaini405 – 1181Myosin motorPROSITE-ProRule annotationAdd BLAST777
Domaini1184 – 1213IQPROSITE-ProRule annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 398Mediates nucleotide-independent binding to F-actin and interaction with GOLPH3By similarityAdd BLAST398
Regioni1 – 34DisorderedSequence analysisAdd BLAST34
Regioni140 – 167DisorderedSequence analysisAdd BLAST28
Regioni1051 – 1071DisorderedSequence analysisAdd BLAST21
Regioni1448 – 1477DisorderedSequence analysisAdd BLAST30
Regioni1848 – 1897DisorderedSequence analysisAdd BLAST50
Regioni1955 – 2050DisorderedSequence analysisAdd BLAST96

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1242 – 1967Sequence analysisAdd BLAST726

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi114 – 118Interaction with actinBy similarity5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi140 – 164Polar residuesSequence analysisAdd BLAST25
Compositional biasi1955 – 1981Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi1995 – 2009Polar residuesSequence analysisAdd BLAST15
Compositional biasi2012 – 2027Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi2030 – 2050Polar residuesSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The myosin motor domain binds ADP and ATP but has no intrinsic ATPase activity. Mediates ADP-dependent binding to actin (By similarity).By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0161, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155768

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9JMH9

Identification of Orthologs from Complete Genome Data

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OMAi
EAWHETE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9JMH9

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01386, MYSc_Myo18, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.42.10, 1 hit
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR031244, MYO18A
IPR001609, Myosin_head_motor_dom
IPR004009, Myosin_N
IPR002928, Myosin_tail
IPR036064, MYSc_Myo18
IPR027417, P-loop_NTPase
IPR001478, PDZ
IPR036034, PDZ_sf

The PANTHER Classification System

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PANTHERi
PTHR45615:SF13, PTHR45615:SF13, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00063, Myosin_head, 2 hits
PF01576, Myosin_tail_1, 1 hit
PF00595, PDZ, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00193, MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00015, IQ, 1 hit
SM00242, MYSc, 1 hit
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156, SSF50156, 1 hit
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS50106, PDZ, 1 hit
PS51844, SH3_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 7 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 7 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All

Isoform 3 (identifier: Q9JMH9-3) [UniParc]FASTAAdd to basket
Also known as: SP-R210L1 Publication

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFNLMKKDKD KDGGRKEKKE KKEKKERMSA AELRSLEEMS MRRGFFNLNR
60 70 80 90 100
SSKRESKTRL EISNPIPIKV ASGSDLHLTD IDSDSNRGSI ILDSGHLSTA
110 120 130 140 150
SSSDDLKGEE GSFRGSVLQR AAKFGSLAKQ NSQMIVKRFS FSQRSRDESA
160 170 180 190 200
SETSTPSEHS AAPSPQVEVR TLEGQLMQHP GLGIPRPGPR SRVPELVTKR
210 220 230 240 250
FPADLRLPAL VPPPPPALRE LELQRRPTGD FGFSLRRTTM LDRAPEGQAY
260 270 280 290 300
RRVVHFAEPG AGTKDLALGL VPGDRLVEIN GQNVENKSRD EIVEMIRQSG
310 320 330 340 350
DSVRLKVQPI PELSELSRSW LRTGEGHRRE PADAKTEEQI AAEEAWYETE
360 370 380 390 400
KVWLVHRDGF SLASQLKSEE LSLPEGKARV KLDHDGAILD VDEDDIEKAN
410 420 430 440 450
APSCDRLEDL ASLVYLNESS VLHTLRQRYG ASLLHTYAGP SLLVLSTRGA
460 470 480 490 500
PAVYSEKVMH MFKGCRREDM APHIYAVAQT AYRAMLMSRQ DQSIVLLGSS
510 520 530 540 550
GSGKTTSFQH LVQYLATIAG TSGTKVFSVE KWQALSTLLE AFGNSPTIMN
560 570 580 590 600
GSATRFSQIL SLDFDQAGQV ASASIQTMLL EKLRVARRPA SEATFNVFYY
610 620 630 640 650
LLACGDATLR TELHLNHLAE NNVFGIVPLS KPEEKQKAAQ QFSKLQAAMK
660 670 680 690 700
VLAISPEEQK TCWLILASIY HLGAAGATKE AAEAGRKQFA RHEWAQKAAY
710 720 730 740 750
LLGCSLEELS SAIFKHQLKG GTLQRSTSFR QGPEESGLGE GTKLSALECL
760 770 780 790 800
EGMASGLYSE LFTLLISLVN RALKSSQHSL CSMMIVDTPG FQNPEWGGSA
810 820 830 840 850
RGASFEELCH NYAQDRLQRL FHERTFLQEL ERYKEDNIEL AFDDLEPVAD
860 870 880 890 900
DSVAAVDQAS HLVRSLAHAD EARGLLWLLE EEALVPGATE DALLDRLFSY
910 920 930 940 950
YGPQEGDKKG QSPLLRSSKP RHFLLGHSHG TNWVEYNVAG WLNYTKQNPA
960 970 980 990 1000
TQNAPRLLQD SQKKIISNLF LGRAGSATVL SGSIAGLEGG SQLALRRATS
1010 1020 1030 1040 1050
MRKTFTTGMA AVKKKSLCIQ IKLQVDALID TIKRSKMHFV HCFLPVAEGW
1060 1070 1080 1090 1100
PGEPRSASSR RVSSSSELDL PPGDPCEAGL LQLDVSLLRA QLRGSRLLDA
1110 1120 1130 1140 1150
MRMYRQGYPD HMVFSEFRRR FDVLAPHLTK KHGRNYIVVD EKRAVEELLE
1160 1170 1180 1190 1200
SLDLEKSSCC LGLSRVFFRA GTLARLEEQR DEQTSRHLTL FQAACRGYLA
1210 1220 1230 1240 1250
RQHFKKRKIQ DLAIRCVQKN IKKNKGVKDW PWWKLFTTVR PLIQVQLSEE
1260 1270 1280 1290 1300
QIRNKDEEIQ QLRSKLEKVE KERNELRLSS DRLETRISEL TSELTDERNT
1310 1320 1330 1340 1350
GESASQLLDA ETAERLRTEK EMKELQTQYD ALKKQMEVME MEVMEARLIR
1360 1370 1380 1390 1400
AAEINGEVDD DDAGGEWRLK YERAVREVDF TKKRLQQELE DKMEVEQQSR
1410 1420 1430 1440 1450
RQLERRLGDL QADSDESQRA LQQLKKKCQR LTAELQDTKL HLEGQQVRNH
1460 1470 1480 1490 1500
ELEKKQRRFD SELSQAHEET QREKLQREKL QREKDMLLAE AFSLKQQMEE
1510 1520 1530 1540 1550
KDLDIAGFTQ KVVSLEAELQ DISSQESKDE ASLAKVKKQL RDLEAKVKDQ
1560 1570 1580 1590 1600
EEELDEQAGS IQMLEQAKLR LEMEMERMRQ THSKEMESRD EEVEEARQSC
1610 1620 1630 1640 1650
QKKLKQMEVQ LEEEYEDKQK ALREKRELES KLSTLSDQVN QRDFESEKRL
1660 1670 1680 1690 1700
RKDLKRTKAL LADAQIMLDH LKNNAPSKRE IAQLKNQLEE SEFTCAAAVK
1710 1720 1730 1740 1750
ARKAMEVEME DLHLQIDDIA KAKTALEEQL SRLQREKNEI QNRLEEDQED
1760 1770 1780 1790 1800
MNELMKKHKA AVAQASRDMA QMNDLQAQIE ESNKEKQELQ EKLQALQSQV
1810 1820 1830 1840 1850
EFLEQSMVDK SLVSRQEAKI RELETRLEFE KTQVKRLENL ASRLKETMEK
1860 1870 1880 1890 1900
LTEERDQRAA AENREKEQNK RLQRQLRDTK EEMSELARKE AEASRKKHEL
1910 1920 1930 1940 1950
EMDLESLEAA NQSLQADLKL AFKRIGDLQA AIEDEMESDE NEDLINSLQD
1960 1970 1980 1990 2000
MVTKYQKKKN KLEGDSDVDS ELEDRVDGVK SWLSKNKGPS KAPSDDGSLK
2010 2020 2030 2040 2050
SSSPTSHWKP LAPDPSDDEH DPVDSISRPR FSHSYLSDSD TEAKLTETSA
Length:2,050
Mass (Da):232,755
Last modified:February 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D82B901F03D73B4
GO
Isoform 1 (identifier: Q9JMH9-1) [UniParc]FASTAAdd to basket
Also known as: Alpha

The sequence of this isoform differs from the canonical sequence as follows:
     1948-1962: Missing.

Show »
Length:2,035
Mass (Da):230,908
Checksum:iC5CE4BB053475119
GO
Isoform 2 (identifier: Q9JMH9-2) [UniParc]FASTAAdd to basket
Also known as: Beta

The sequence of this isoform differs from the canonical sequence as follows:
     1-331: Missing.
     332-333: AD → ML

Show »
Length:1,719
Mass (Da):195,894
Checksum:iF533D2057E1E555A
GO
Isoform 4 (identifier: Q9JMH9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1567-1603: Missing.
     1948-1962: Missing.

Show »
Length:1,998
Mass (Da):226,357
Checksum:i78A7FB6FF72A32D1
GO
Isoform 5 (identifier: Q9JMH9-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-331: Missing.
     332-333: AD → ML
     1948-1962: Missing.

Show »
Length:1,704
Mass (Da):194,047
Checksum:i494995EAC30B1C00
GO
Isoform 6 (identifier: Q9JMH9-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     333-333: D → DLDPEAASPAYSQ

Show »
Length:2,062
Mass (Da):233,985
Checksum:i823FB756634D16B9
GO
Isoform 7 (identifier: Q9JMH9-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-331: Missing.
     332-333: AD → MLLDPEAASPAYSQ
     1948-1962: Missing.

Show »
Length:1,716
Mass (Da):195,277
Checksum:i893846897B291215
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QAX2E9QAX2_MOUSE
Unconventional myosin-XVIIIa
Myo18a
2,083Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q405E9Q405_MOUSE
Unconventional myosin-XVIIIa
Myo18a
1,700Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B2RRE2B2RRE2_MOUSE
Myo18a protein
Myo18a
2,047Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1C7ZN10A0A1C7ZN10_MOUSE
Unconventional myosin-XVIIIa
Myo18a
1,722Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QA74E9QA74_MOUSE
Unconventional myosin-XVIIIa
Myo18a
1,642Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K3W4L0K3W4L0_MOUSE
Unconventional myosin-XVIIIa
Myo18a
2,036Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6ZGN3F6ZGN3_MOUSE
Unconventional myosin-XVIIIa
Myo18a
501Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PUR2E9PUR2_MOUSE
Unconventional myosin-XVIIIa
Myo18a
307Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q0K8E9Q0K8_MOUSE
Unconventional myosin-XVIIIa
Myo18a
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti399A → T in BAE28009 (PubMed:16141072).Curated1
Sequence conflicti466R → Q in BAE42402 (PubMed:16141072).Curated1
Sequence conflicti680 – 683Missing in BAE42402 (PubMed:16141072).Curated4
Sequence conflicti680E → EPLEEQD in BAE28009 (PubMed:16141072).Curated1
Sequence conflicti798G → D in BAE42402 (PubMed:16141072).Curated1
Sequence conflicti1362D → N in BAE42402 (PubMed:16141072).Curated1
Sequence conflicti1655K → R in BAE28009 (PubMed:16141072).Curated1
Sequence conflicti1978G → R in AAV80766 (PubMed:16087679).Curated1
Sequence conflicti1990S → P in AAV80765 (PubMed:16087679).Curated1
Sequence conflicti2027S → F in AAV80767 (PubMed:16087679).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0078731 – 331Missing in isoform 2, isoform 5 and isoform 7. 1 PublicationAdd BLAST331
Alternative sequenceiVSP_007874332 – 333AD → ML in isoform 2 and isoform 5. 1 Publication2
Alternative sequenceiVSP_023059332 – 333AD → MLLDPEAASPAYSQ in isoform 7. Curated2
Alternative sequenceiVSP_023060333D → DLDPEAASPAYSQ in isoform 6. Curated1
Alternative sequenceiVSP_0230611567 – 1603Missing in isoform 4. CuratedAdd BLAST37
Alternative sequenceiVSP_0230621948 – 1962Missing in isoform 1, isoform 4, isoform 5 and isoform 7. 4 PublicationsAdd BLAST15

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB026497 mRNA Translation: BAA93660.1
AK137574 mRNA Translation: BAE23413.1
AK147584 mRNA Translation: BAE28009.1
AK171342 mRNA Translation: BAE42402.1
AL591065 Genomic DNA No translation available.
BC046638 mRNA Translation: AAH46638.1
AY692137 mRNA Translation: AAV80765.1
AY692138 mRNA Translation: AAV80766.1
AY692139 mRNA Translation: AAV80767.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25085.1 [Q9JMH9-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001278141.1, NM_001291212.1
NP_001278142.1, NM_001291213.1
NP_001278143.1, NM_001291214.1
NP_001278144.1, NM_001291215.1
NP_035716.1, NM_011586.3 [Q9JMH9-1]
XP_006533667.1, XM_006533604.3 [Q9JMH9-3]
XP_006533669.1, XM_006533606.2 [Q9JMH9-1]
XP_006533677.2, XM_006533614.3 [Q9JMH9-2]
XP_017170115.1, XM_017314626.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000092884; ENSMUSP00000090560; ENSMUSG00000000631 [Q9JMH9-5]
ENSMUST00000092887; ENSMUSP00000090563; ENSMUSG00000000631 [Q9JMH9-1]
ENSMUST00000102488; ENSMUSP00000099546; ENSMUSG00000000631 [Q9JMH9-1]
ENSMUST00000108375; ENSMUSP00000104012; ENSMUSG00000000631 [Q9JMH9-3]
ENSMUST00000108376; ENSMUSP00000104013; ENSMUSG00000000631 [Q9JMH9-4]
ENSMUST00000130305; ENSMUSP00000119574; ENSMUSG00000000631 [Q9JMH9-7]
ENSMUST00000130627; ENSMUSP00000119839; ENSMUSG00000000631 [Q9JMH9-6]
ENSMUST00000164334; ENSMUSP00000131771; ENSMUSG00000000631 [Q9JMH9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
360013

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:360013

UCSC genome browser

More...
UCSCi
uc007khg.2, mouse [Q9JMH9-1]
uc007khh.2, mouse [Q9JMH9-5]
uc007khi.2, mouse [Q9JMH9-7]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026497 mRNA Translation: BAA93660.1
AK137574 mRNA Translation: BAE23413.1
AK147584 mRNA Translation: BAE28009.1
AK171342 mRNA Translation: BAE42402.1
AL591065 Genomic DNA No translation available.
BC046638 mRNA Translation: AAH46638.1
AY692137 mRNA Translation: AAV80765.1
AY692138 mRNA Translation: AAV80766.1
AY692139 mRNA Translation: AAV80767.1
CCDSiCCDS25085.1 [Q9JMH9-1]
RefSeqiNP_001278141.1, NM_001291212.1
NP_001278142.1, NM_001291213.1
NP_001278143.1, NM_001291214.1
NP_001278144.1, NM_001291215.1
NP_035716.1, NM_011586.3 [Q9JMH9-1]
XP_006533667.1, XM_006533604.3 [Q9JMH9-3]
XP_006533669.1, XM_006533606.2 [Q9JMH9-1]
XP_006533677.2, XM_006533614.3 [Q9JMH9-2]
XP_017170115.1, XM_017314626.1

3D structure databases

SMRiQ9JMH9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi237427, 14 interactors
IntActiQ9JMH9, 4 interactors
STRINGi10090.ENSMUSP00000130696

PTM databases

iPTMnetiQ9JMH9
PhosphoSitePlusiQ9JMH9

Proteomic databases

jPOSTiQ9JMH9
MaxQBiQ9JMH9
PaxDbiQ9JMH9
PeptideAtlasiQ9JMH9
PRIDEiQ9JMH9
ProteomicsDBi252618 [Q9JMH9-3]
252619 [Q9JMH9-1]
252620 [Q9JMH9-2]
252621 [Q9JMH9-4]
252622 [Q9JMH9-5]
252623 [Q9JMH9-6]
252624 [Q9JMH9-7]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
7183, 78 antibodies from 23 providers

The DNASU plasmid repository

More...
DNASUi
360013

Genome annotation databases

EnsembliENSMUST00000092884; ENSMUSP00000090560; ENSMUSG00000000631 [Q9JMH9-5]
ENSMUST00000092887; ENSMUSP00000090563; ENSMUSG00000000631 [Q9JMH9-1]
ENSMUST00000102488; ENSMUSP00000099546; ENSMUSG00000000631 [Q9JMH9-1]
ENSMUST00000108375; ENSMUSP00000104012; ENSMUSG00000000631 [Q9JMH9-3]
ENSMUST00000108376; ENSMUSP00000104013; ENSMUSG00000000631 [Q9JMH9-4]
ENSMUST00000130305; ENSMUSP00000119574; ENSMUSG00000000631 [Q9JMH9-7]
ENSMUST00000130627; ENSMUSP00000119839; ENSMUSG00000000631 [Q9JMH9-6]
ENSMUST00000164334; ENSMUSP00000131771; ENSMUSG00000000631 [Q9JMH9-2]
GeneIDi360013
KEGGimmu:360013
UCSCiuc007khg.2, mouse [Q9JMH9-1]
uc007khh.2, mouse [Q9JMH9-5]
uc007khi.2, mouse [Q9JMH9-7]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
399687
MGIiMGI:2667185, Myo18a
VEuPathDBiHostDB:ENSMUSG00000000631

Phylogenomic databases

eggNOGiKOG0161, Eukaryota
GeneTreeiENSGT00940000155768
InParanoidiQ9JMH9
OMAiEAWHETE
PhylomeDBiQ9JMH9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
360013, 0 hits in 62 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Myo18a, mouse

Protein Ontology

More...
PROi
PR:Q9JMH9
RNActiQ9JMH9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000000631, Expressed in hindlimb stylopod muscle and 308 other tissues
ExpressionAtlasiQ9JMH9, baseline and differential
GenevisibleiQ9JMH9, MM

Family and domain databases

CDDicd01386, MYSc_Myo18, 1 hit
Gene3Di2.30.42.10, 1 hit
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR031244, MYO18A
IPR001609, Myosin_head_motor_dom
IPR004009, Myosin_N
IPR002928, Myosin_tail
IPR036064, MYSc_Myo18
IPR027417, P-loop_NTPase
IPR001478, PDZ
IPR036034, PDZ_sf
PANTHERiPTHR45615:SF13, PTHR45615:SF13, 1 hit
PfamiView protein in Pfam
PF00063, Myosin_head, 2 hits
PF01576, Myosin_tail_1, 1 hit
PF00595, PDZ, 1 hit
PRINTSiPR00193, MYOSINHEAVY
SMARTiView protein in SMART
SM00015, IQ, 1 hit
SM00242, MYSc, 1 hit
SM00228, PDZ, 1 hit
SUPFAMiSSF50156, SSF50156, 1 hit
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS50106, PDZ, 1 hit
PS51844, SH3_LIKE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMY18A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9JMH9
Secondary accession number(s): Q3TBB2
, Q3UH48, Q3UV60, Q5QD54, Q5QD55, Q5QD56, Q5SYN8, Q5SYN9, Q5SYP0, Q5SYP1, Q811D7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: February 6, 2007
Last modified: February 23, 2022
This is version 173 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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