UniProtKB - Q9JMG9 (Q9JMG9_MOUSE)
Protein
Submitted name:
POZ (BTB) and AT hook-containing zinc finger 1
Gene
Patz1
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: MGI
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: NTNU_SB
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: NTNU_SB
- ubiquitin protein ligase binding Source: Ensembl
GO - Biological processi
- male gonad development Source: MGI
- negative regulation of transcription, DNA-templated Source: MGI
- positive regulation of transcription, DNA-templated Source: MGI
- positive regulation of transcription by RNA polymerase II Source: NTNU_SB
- regulation of gene expression Source: MGI
- regulation of transcription, DNA-templated Source: MGI
- regulation of transcription by RNA polymerase II Source: GO_Central
- spermatogenesis Source: MGI
- T cell differentiation Source: MGI
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: POZ (BTB) and AT hook-containing zinc finger 1ImportedSubmitted name: Transcription factor MAZRImported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1891832, Patz1 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleoplasm Source: MGI
- nucleus Source: MGI
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000020453, Expressed in embryo and 313 other tissues |
Interactioni
Binary interactionsi
Q9JMG9
With | #Exp. | IntAct |
---|---|---|
Mylk [Q6PDN3] | 3 | EBI-647451,EBI-647412 |
GO - Molecular functioni
- ubiquitin protein ligase binding Source: Ensembl
Protein-protein interaction databases
IntActi | Q9JMG9, 2 interactors |
STRINGi | 10090.ENSMUSP00000050684 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 41 – 130 | BTBInterPro annotationAdd BLAST | 90 | |
Domaini | 292 – 314 | C2H2-typeInterPro annotationAdd BLAST | 23 | |
Domaini | 355 – 382 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 383 – 410 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 413 – 441 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 442 – 469 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 559 – 582 | C2H2-typeInterPro annotationAdd BLAST | 24 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 250 – 279 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 332 – 351 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 518 – 537 | DisorderedSequence analysisAdd BLAST | 20 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159296 |
HOGENOMi | CLU_030477_1_0_1 |
OMAi | QVACDIC |
OrthoDBi | 1318335at2759 |
TreeFami | TF331686 |
Family and domain databases
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR000637, HMGI/Y_DNA-bd_CS IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 4 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00354, HMGI_Y, 1 hit PS00028, ZINC_FINGER_C2H2_1, 6 hits PS50157, ZINC_FINGER_C2H2_2, 6 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q9JMG9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERVNDASCG PSGCYTYQVS RHSTEMLHNL NQQRKNGGRF CDVLLRVGDE
60 70 80 90 100
SFPAHRAVLA ACSEYFESVF SAQLGDGGAA DGGPADVGGA AAAPGGGAGG
110 120 130 140 150
SRELEMHTIS SKVFGDILDF AYTSRIVVRL ESFPELMTAA KFLLMRSVIE
160 170 180 190 200
ICQEVIKQSN VQILVPPARA DIMLFRPPGT SDLGFPLDMT NGAAMAANSN
210 220 230 240 250
GIAGSMQPEE EAARATGAAI AGQASLPVLP GVDRLPMVAG PLSPQLLTSP
260 270 280 290 300
FPNVASSAPP LTSKRGRGRP RKANLLDSMF GSPGGLREAG ILPCGLCGKV
310 320 330 340 350
FTDANRLRQH EAQHGVTSLQ LGYIDLPPPR LGENGLPISE DPDGPRKRSR
360 370 380 390 400
TRKQVACEIC GKIFRDVYHL NRHKLSHSGE KPYSCPVCGL RFKRKDRMSY
410 420 430 440 450
HVRSHDGSVG KPYICQSCGK GFSRPDHLNG HIKQVHTSER PHKCQTCNAS
460 470 480 490 500
FATRDRLRSH LACHEDKVPC QVCGKYLRAA YMADHLKKHS EGPSNFCSIC
510 520 530 540 550
NREGQKCSHQ DLIESSDSYG DLSDASDLKT PEKQSANGSF SCDVAVPKNK
560 570 580 590 600
MESDGEKKYP CPECGSFFRS KSYLNKHIQK VHVRALGGPL GDLGPALGSP
610 620 630 640
FSPQQNMSLL ESFGFQIVQS AFASSLVDPE VDQQPMGPEG K
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ5NBY9 | Q5NBY9_MOUSE | POZ (BTB) and AT hook-containing zi... | Patz1 | 687 | Annotation score: | ||
Q5NBZ2 | Q5NBZ2_MOUSE | POZ (BTB) and AT hook-containing zi... | Patz1 Zfp278 | 537 | Annotation score: | ||
Q5NBZ1 | Q5NBZ1_MOUSE | POZ (BTB) and AT hook-containing zi... | Patz1 | 537 | Annotation score: | ||
Q7TNQ3 | Q7TNQ3_MOUSE | POZ (BTB) and AT hook-containing zi... | Patz1 Zfp278 | 102 | Annotation score: | ||
Q5NBY8 | Q5NBY8_MOUSE | POZ (BTB) and AT hook-containing zi... | Patz1 | 70 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL671968 Genomic DNA No translation available. AB029397 mRNA Translation: BAA90874.1 |
RefSeqi | NP_062520.1, NM_019574.3 |
Genome annotation databases
Ensembli | ENSMUST00000057089; ENSMUSP00000050684; ENSMUSG00000020453 |
GeneIDi | 56218 |
UCSCi | uc007hsn.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL671968 Genomic DNA No translation available. AB029397 mRNA Translation: BAA90874.1 |
RefSeqi | NP_062520.1, NM_019574.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9JMG9, 2 interactors |
STRINGi | 10090.ENSMUSP00000050684 |
Protocols and materials databases
Antibodypediai | 25019, 166 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000057089; ENSMUSP00000050684; ENSMUSG00000020453 |
GeneIDi | 56218 |
UCSCi | uc007hsn.2, mouse |
Organism-specific databases
CTDi | 23598 |
MGIi | MGI:1891832, Patz1 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159296 |
HOGENOMi | CLU_030477_1_0_1 |
OMAi | QVACDIC |
OrthoDBi | 1318335at2759 |
TreeFami | TF331686 |
Miscellaneous databases
BioGRID-ORCSi | 56218, 0 hits in 12 CRISPR screens |
ChiTaRSi | Patz1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000020453, Expressed in embryo and 313 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR000637, HMGI/Y_DNA-bd_CS IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 4 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00354, HMGI_Y, 1 hit PS00028, ZINC_FINGER_C2H2_1, 6 hits PS50157, ZINC_FINGER_C2H2_2, 6 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9JMG9_MOUSE | |
Accessioni | Q9JMG9Primary (citable) accession number: Q9JMG9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2000 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 170 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |