Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Calmodulin-4

Gene

Calm4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Implicated in the early stage of ectopic ossification.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi21 – 321PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi57 – 682PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi93 – 1043PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

  • calcium ion binding Source: MGI
  • enzyme regulator activity Source: GO_Central

GO - Biological processi

Keywordsi

LigandCalcium, Metal-binding

Enzyme and pathway databases

ReactomeiR-MMU-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Calmodulin-4
Alternative name(s):
Calcium-binding protein Dd112
Gene namesi
Name:Calm4
Synonyms:Dd112
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:1931464 Calm4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000738561 – 148Calmodulin-4Add BLAST148

Proteomic databases

MaxQBiQ9JM83
PaxDbiQ9JM83
PRIDEiQ9JM83

PTM databases

iPTMnetiQ9JM83
PhosphoSitePlusiQ9JM83

Expressioni

Gene expression databases

BgeeiENSMUSG00000033765 Expressed in 66 organ(s), highest expression level in skin epidermis
CleanExiMM_CALM4
GenevisibleiQ9JM83 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041636

Structurei

3D structure databases

ProteinModelPortaliQ9JM83
SMRiQ9JM83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 43EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini44 – 79EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini80 – 115EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini116 – 148EF-hand 4PROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00760000118901
HOGENOMiHOG000233018
HOVERGENiHBG012180
InParanoidiQ9JM83
KOiK02183
OMAiYKSAFSA
OrthoDBiEOG091G0RVC
PhylomeDBiQ9JM83
TreeFamiTF339519

Family and domain databases

CDDicd00051 EFh, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 3 hits
PS50222 EF_HAND_2, 4 hits

Sequencei

Sequence statusi: Complete.

Q9JM83-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHGFTKEEV AEFQAAFNRF DKNKDGHISV EELGDVMKQL GKNLPEKDLK
60 70 80 90 100
ALISKLDTDG DGKISFEEFL TAIEKYKKGH RAGELRAVFN VLDQNGDGYI
110 120 130 140
TVDELKESLS KLGESLSQEE LEDMIRVADV DQDGKVKYEE FVRLHVEN
Length:148
Mass (Da):16,767
Last modified:June 1, 2001 - v2
Checksum:i2AE22BC738AD2F9D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti9E → V in BAB22914 (PubMed:16141072).Curated1
Sequence conflicti124M → V in BAB22914 (PubMed:16141072).Curated1
Sequence conflicti146 – 148VEN → I in BAA95412 (Ref. 1) Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB036744 Genomic DNA Translation: BAA95412.1
AK009956 mRNA Translation: BAB26608.1
AK009664 mRNA Translation: BAB26425.1
AK003648 mRNA Translation: BAB22914.1
CCDSiCCDS26215.1
RefSeqiNP_064420.2, NM_020036.4
UniGeneiMm.21075

Genome annotation databases

EnsembliENSMUST00000042219; ENSMUSP00000041636; ENSMUSG00000033765
GeneIDi80796
KEGGimmu:80796
UCSCiuc007pjb.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB036744 Genomic DNA Translation: BAA95412.1
AK009956 mRNA Translation: BAB26608.1
AK009664 mRNA Translation: BAB26425.1
AK003648 mRNA Translation: BAB22914.1
CCDSiCCDS26215.1
RefSeqiNP_064420.2, NM_020036.4
UniGeneiMm.21075

3D structure databases

ProteinModelPortaliQ9JM83
SMRiQ9JM83
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041636

PTM databases

iPTMnetiQ9JM83
PhosphoSitePlusiQ9JM83

Proteomic databases

MaxQBiQ9JM83
PaxDbiQ9JM83
PRIDEiQ9JM83

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042219; ENSMUSP00000041636; ENSMUSG00000033765
GeneIDi80796
KEGGimmu:80796
UCSCiuc007pjb.1 mouse

Organism-specific databases

CTDi80796
MGIiMGI:1931464 Calm4

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00760000118901
HOGENOMiHOG000233018
HOVERGENiHBG012180
InParanoidiQ9JM83
KOiK02183
OMAiYKSAFSA
OrthoDBiEOG091G0RVC
PhylomeDBiQ9JM83
TreeFamiTF339519

Enzyme and pathway databases

ReactomeiR-MMU-6798695 Neutrophil degranulation

Miscellaneous databases

PROiPR:Q9JM83
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000033765 Expressed in 66 organ(s), highest expression level in skin epidermis
CleanExiMM_CALM4
GenevisibleiQ9JM83 MM

Family and domain databases

CDDicd00051 EFh, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 3 hits
PS50222 EF_HAND_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiCALM4_MOUSE
AccessioniPrimary (citable) accession number: Q9JM83
Secondary accession number(s): Q9CR31, Q9D1E9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again