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UniProtKB - Q9JLQ4 (Q9JLQ4_MOUSE)
Protein
Submitted name:
Pleiomorphic adenoma gene-like 1
Gene
Plagl1
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: MGI
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: MGI
- DNA-binding transcription factor activity Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: MGI
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: MGI
- regulation of gene expression Source: MGI
- regulation of transcription by RNA polymerase II Source: GO_Central
- skeletal muscle cell differentiation Source: MGI
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Pleiomorphic adenoma gene-like 1ImportedSubmitted name: Zinc finger protein ZAC1Imported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1100874, Plagl1 |
VEuPathDBi | HostDB:ENSMUSG00000019817 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus Source: MGI
Nucleus
- nuclear body Source: MGI
Other locations
- intracellular membrane-bounded organelle Source: MGI
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000019817, Expressed in umbilical cord and 374 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9JLQ4, 1 interactor |
STRINGi | 10090.ENSMUSP00000112847 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 31 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 32 – 61 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 62 – 89 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 91 – 118 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 156 – 183 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 184 – 212 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 524 – 557 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 586 – 688 | DisorderedSequence analysisAdd BLAST | 103 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 526 – 553 | Pro residuesSequence analysisAdd BLAST | 28 | |
Compositional biasi | 596 – 663 | Acidic residuesSequence analysisAdd BLAST | 68 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162004 |
HOGENOMi | CLU_405410_0_0_1 |
OMAi | HHAPREK |
OrthoDBi | 1318335at2759 |
TreeFami | TF332024 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 6 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q9JLQ4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPFRCQKCG KSFVTLEKFT IHNYSHSRER PFKCSKAECG KAFVSKYKLM
60 70 80 90 100
RHMATHSPQK IHQCTHCEKT FNRKDHLKNH LQTHDPNKIS YACDDCGKKY
110 120 130 140 150
HTMLGYKRHL ALHSASNGDL TCGVCTLELG STEVLLDHLK SHAEEKANQA
160 170 180 190 200
PREKKYQCDH CDRCFYTRKD VRRHLVVHTG CKDFLCQFCA QRFGRKDHLT
210 220 230 240 250
RHTKKTHSQE LMQENMQAGD YQSNFQLIAP STSFQIKVDP MPPFQLGAAP
260 270 280 290 300
ENGLDGGLPP EVHGLVLAAP EEAPQPMPPL EPLEPLEPLE PLEPMQSLEP
310 320 330 340 350
LQPLEPMQPL EPMQPLEPMQ PLEPLEPLEP MQPLEPMQPL EPMQPMLPMQ
360 370 380 390 400
PMQPMQPMQP MLPMQPMLPM QPMQPMQPML PMPEPSFTLH PGVVPTSPPP
410 420 430 440 450
IILQEHKYNP VPTSYAPFVG MPVKADGKAF CNVGFFEEFP LQEPQAPLKF
460 470 480 490 500
NPCFEMPMEG FGKVTLSKEL LVDAVNIAIP ASLEISSLLG FWQLPPPTPQ
510 520 530 540 550
NGFVNSTIPV GPGEPLPHRI TCLAQQQPPP LPPPPPLPLP QPLPVPQPLP
560 570 580 590 600
QPQMQPQFQL QIQPQMQPQM QLQPLQLQLP QLLPQLQPQQ QPDPEPEPEP
610 620 630 640 650
EPEPEPEPEP EPEPEPEPEP EPEPEEEQEE AEEEAEEGAE EGAEPEAQAE
660 670 680 690 700
EEEEEEEAEE PQPEEAQIAV SAVNLGQPPL PPTPHIFTAG SNTAILPHFH
HAFR
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ3UQW2 | Q3UQW2_MOUSE | Pleiomorphic adenoma gene-like 1 | Plagl1 | 678 | Annotation score: | ||
B0QZX4 | B0QZX4_MOUSE | Pleiomorphic adenoma gene-like 1 | Plagl1 | 117 | Annotation score: | ||
A0A0A6YWE3 | A0A0A6YWE3_MOUSE | Pleiomorphic adenoma gene-like 1 | Plagl1 | 121 | Annotation score: | ||
B0QZX5 | B0QZX5_MOUSE | Pleiomorphic adenoma gene-like 1 | Plagl1 | 17 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF147785 mRNA Translation: AAF34245.1 |
RefSeqi | NP_033564.2, NM_009538.2 |
Genome annotation databases
Ensembli | ENSMUST00000121646; ENSMUSP00000112847; ENSMUSG00000019817 |
GeneIDi | 22634 |
UCSCi | uc007ekm.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF147785 mRNA Translation: AAF34245.1 |
RefSeqi | NP_033564.2, NM_009538.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9JLQ4, 1 interactor |
STRINGi | 10090.ENSMUSP00000112847 |
Protocols and materials databases
Antibodypediai | 19825, 235 antibodies from 30 providers |
DNASUi | 22634 |
Genome annotation databases
Ensembli | ENSMUST00000121646; ENSMUSP00000112847; ENSMUSG00000019817 |
GeneIDi | 22634 |
UCSCi | uc007ekm.2, mouse |
Organism-specific databases
CTDi | 5325 |
MGIi | MGI:1100874, Plagl1 |
VEuPathDBi | HostDB:ENSMUSG00000019817 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162004 |
HOGENOMi | CLU_405410_0_0_1 |
OMAi | HHAPREK |
OrthoDBi | 1318335at2759 |
TreeFami | TF332024 |
Miscellaneous databases
BioGRID-ORCSi | 22634, 0 hits in 65 CRISPR screens |
ChiTaRSi | Plagl1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000019817, Expressed in umbilical cord and 374 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 6 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9JLQ4_MOUSE | |
Accessioni | Q9JLQ4Primary (citable) accession number: Q9JLQ4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2000 |
Last sequence update: | October 1, 2000 | |
Last modified: | January 19, 2022 | |
This is version 153 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |