Zic1

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl
RNA polymerase II regulatory region sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

adult walking behavior Source: Ensembl
brain development Source: Ensembl
pattern specification process Source: Ensembl
positive regulation of protein import into nucleus Source: Ensembl
regulation of smoothened signaling pathway Source: Ensembl
spinal cord development Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Zic family member 1Imported Submitted name: Zic proteinImported Submitted name: Zinc finger protein of the cerebellum 1, isoform CRA_aImported
Gene namesⁱ	Name:Zic1Imported Synonyms:zicImported ORF Names:rCG_25795Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 8

Organism-specific databases

Rat genome database More...RGDⁱ	620110 Zic1

RGDⁱ

620110 Zic1

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	Q9JKY2

PRIDEⁱ

Q9JKY2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000014644 Expressed in 2 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000014644 Expressed in 2 organ(s), highest expression level in brain

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000019860

STRINGⁱ

10116.ENSRNOP00000019860

Structureⁱ

3D structure databases

SMRⁱ	Q9JKY2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	274 – 301	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	302 – 331	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	332 – 361	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	362 – 389	C2H2-typeInterPro annotationAdd BLAST	28

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140802
HOGENOMⁱ	HOG000232057
HOVERGENⁱ	HBG007135
KEGG Orthology (KO) More...KOⁱ	K09224
OMAⁱ	MGAFKIN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0M59
TreeFamⁱ	TF351425

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9JKY2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLLDAGPQYP AIGVTTFGAS RHHSAGDVAE RDVGLGINPF ADGMGAFKLN 
        60         70         80         90        100
PSSHELASAG QTAFTSQAPG YAAAAALGHH HHPGHVGSYS SAAFNSTRDF 
       110        120        130        140        150
LFRNRGFGDA AAAASAQHSL FAASAGGFGG PHGHTDAAGH LLFSGLHEQA 
       160        170        180        190        200
AGHASPNVVN GQMRLGFSGD MYPRPEQYGQ VTSPRSEHYA APQLHGYGPM 
       210        220        230        240        250
NVNMAAHHGA GAFFRYMRQP IKQELICKWI EPEQLANPKK SCNKTFSTMH 
       260        270        280        290        300
ELVTHVTVEH VGGPEQSNHI CFWEECPREG KPFKAKYKLV NHIRVHTGEK 
       310        320        330        340        350
PFPCPFPGCG KVFARSENLK IHKRTHTGEK PFKCEFEGCD RRFANSSDRK 
       360        370        380        390        400
KHMHVHTSDK PYLCKMCDKS YTHPSSLRKH MKVHESSSQG SQPSPAASSG 
       410        420        430        440 
YESSTPPTIV SPTTDNPTTS SMSPSSSAVH HTAGHSALSS NFNEWYV

Length:447

Mass (Da):48,331

Last modified:October 1, 2000 - v1

Checksum:ⁱD41F412F44C2AD3D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07071064 Genomic DNA No translation available. AF221839 mRNA Translation: AAF34656.1 CH473954 Genomic DNA Translation: EDL77550.1
NCBI Reference Sequences More...RefSeqⁱ	NP_073168.1, NM_022677.1 XP_008764676.1, XM_008766454.2
UniGeneⁱ	Rn.161923

Genome annotation databases

Ensemblⁱ	ENSRNOT00000019860; ENSRNOP00000019860; ENSRNOG00000014644
GeneIDⁱ	64618
KEGGⁱ	rno:64618
UCSC genome browser More...UCSCⁱ	RGD:620110 rat

Protein	Similar proteins		Species	Score	Length	Source
Q9JKY2	Zinc finger protein ZIC 1		MOUSE		447	UniRef100_P46684
zinc finger protein ZIC 1		MESAU		447
Uncharacterized protein		NEOLE		447
Zinc finger protein ZIC 1		CRIGR		248
UPI00022F35C2		CRIGR		274

Protein	Similar proteins		Species	Score	Length	Source
Q9JKY2	Zinc finger protein ZIC 1		MOUSE		447	UniRef90_P46684
Zinc finger protein ZIC 1		HUMAN		447
zinc finger protein ZIC 1		MESAU		447
Uncharacterized protein		NEOLE		447
Zinc finger protein ZIC 1		CRIGR		248
+62

Protein	Similar proteins		Species	Score	Length	Source
Q9JKY2	Zinc finger protein ZIC 1		MOUSE		447	UniRef50_P46684
Zinc finger protein ZIC 1		HUMAN		447
zinc finger protein ZIC 1		MESAU		447
Uncharacterized protein		NEOLE		447
Zinc finger protein ZIC 1		CRIGR		248
+771

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07071064 Genomic DNA No translation available. AF221839 mRNA Translation: AAF34656.1 CH473954 Genomic DNA Translation: EDL77550.1
RefSeqⁱ	NP_073168.1, NM_022677.1 XP_008764676.1, XM_008766454.2
UniGeneⁱ	Rn.161923

3D structure databases

SMRⁱ	Q9JKY2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000019860

STRINGⁱ

10116.ENSRNOP00000019860

Proteomic databases

PRIDEⁱ	Q9JKY2

PRIDEⁱ

Q9JKY2

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000019860; ENSRNOP00000019860; ENSRNOG00000014644
GeneIDⁱ	64618
KEGGⁱ	rno:64618
UCSCⁱ	RGD:620110 rat

Organism-specific databases

CTDⁱ	7545
RGDⁱ	620110 Zic1

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00900000140802
HOGENOMⁱ	HOG000232057
HOVERGENⁱ	HBG007135
KOⁱ	K09224
OMAⁱ	MGAFKIN
OrthoDBⁱ	EOG091G0M59
TreeFamⁱ	TF351425

Gene expression databases

Bgeeⁱ	ENSRNOG00000014644 Expressed in 2 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000014644 Expressed in 2 organ(s), highest expression level in brain

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q9JKY2_RAT
Accessionⁱ	Q9JKY2Primary (citable) accession number: Q9JKY2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 1, 2000
	Last sequence update:	October 1, 2000
	Last modified:	November 7, 2018
	This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9JKY2 (Q9JKY2_RAT)

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Zic family member 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ