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Protein

39S ribosomal protein L39, mitochondrial

Gene

Mrpl39

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • mitochondrial genome maintenance Source: MGI
  • translation Source: MGI

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L39, mitochondrial
Short name:
L39mt
Short name:
MRP-L39
Gene namesi
Name:Mrpl39
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1351620 Mrpl39

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000876851 – 33639S ribosomal protein L39, mitochondrialAdd BLAST336

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei123N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9JKF7
MaxQBiQ9JKF7
PaxDbiQ9JKF7
PeptideAtlasiQ9JKF7
PRIDEiQ9JKF7

PTM databases

iPTMnetiQ9JKF7
PhosphoSitePlusiQ9JKF7

Expressioni

Gene expression databases

BgeeiENSMUSG00000022889 Expressed in 286 organ(s), highest expression level in testis
CleanExiMM_MRPL39
GenevisibleiQ9JKF7 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi205200, 1 interactor
IntActiQ9JKF7, 1 interactor
STRINGi10090.ENSMUSP00000112283

Structurei

3D structure databases

ProteinModelPortaliQ9JKF7
SMRiQ9JKF7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1637 Eukaryota
COG0441 LUCA
GeneTreeiENSGT00390000002149
HOGENOMiHOG000000683
HOVERGENiHBG023123
InParanoidiQ9JKF7
KOiK17420
OMAiPYNCAMH
OrthoDBiEOG091G0CTH
TreeFamiTF300858

Family and domain databases

Gene3Di3.10.20.30, 1 hit
InterProiView protein in InterPro
IPR012675 Beta-grasp_dom_sf
IPR012676 TGS-like
IPR018163 Thr/Ala-tRNA-synth_IIc_edit
SUPFAMiSSF55186 SSF55186, 1 hit
SSF81271 SSF81271, 1 hit

Sequencei

Sequence statusi: Complete.

Q9JKF7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATAVGRLVL RRPGAGGGAR WRFIATSPAA ELSPTELTEM RNDLFNREKS
60 70 80 90 100
RQLSLTPRTE KIEVKHVGKT DPGTVFVMNK NISTPYSCAM HLSEWYCSKS
110 120 130 140 150
ILALVDGQPW DMYKPLTKSC EIKFLTFKDP DPKEVNKAYW RSCAMMLGCV
160 170 180 190 200
IERAFKDDYV VSLVRAPEVP VIAGAFCYDV TLDKRLDEWM PTKENLRSFT
210 220 230 240 250
KDAHALIYRD LPFETLDVDA RVALEIFQHN KYKVDFIEEK ASQNPERIVK
260 270 280 290 300
LHRIGDFIDV SEGPLIPRTS VCFQYEVSAV HNLNPSQPNL IRRFQGLSLP
310 320 330
THLRAQFTIW DKLVERSRKM VTEDEVRQTE NTESTQ
Length:336
Mass (Da):38,549
Last modified:July 27, 2011 - v4
Checksum:i20F03B4A8E874E5D
GO

Sequence cautioni

The sequence AAF44697 differs from that shown. Reason: Frameshift at position 16.Curated
The sequence AAH12274 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH16561 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB25185 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti133K → R in AAH16561 (PubMed:15489334).Curated1
Sequence conflicti164V → L in AAH16561 (PubMed:15489334).Curated1
Sequence conflicti283L → F in AAF44697 (Ref. 1) Curated1
Sequence conflicti315E → G in AAH16561 (PubMed:15489334).Curated1
Sequence conflicti317S → F in AAF44697 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF239728 mRNA Translation: AAF44697.1 Sequence problems.
AK007681 mRNA Translation: BAB25185.1 Different initiation.
CT027693 Genomic DNA Translation: CAO78080.1
CH466521 Genomic DNA Translation: EDK98312.1
BC012274 mRNA Translation: AAH12274.1 Different initiation.
BC016561 mRNA Translation: AAH16561.1 Different initiation.
CCDSiCCDS57035.1
RefSeqiNP_059100.3, NM_017404.4
UniGeneiMm.103655

Genome annotation databases

EnsembliENSMUST00000116584; ENSMUSP00000112283; ENSMUSG00000022889
GeneIDi27393
KEGGimmu:27393
UCSCiuc007zte.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF239728 mRNA Translation: AAF44697.1 Sequence problems.
AK007681 mRNA Translation: BAB25185.1 Different initiation.
CT027693 Genomic DNA Translation: CAO78080.1
CH466521 Genomic DNA Translation: EDK98312.1
BC012274 mRNA Translation: AAH12274.1 Different initiation.
BC016561 mRNA Translation: AAH16561.1 Different initiation.
CCDSiCCDS57035.1
RefSeqiNP_059100.3, NM_017404.4
UniGeneiMm.103655

3D structure databases

ProteinModelPortaliQ9JKF7
SMRiQ9JKF7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi205200, 1 interactor
IntActiQ9JKF7, 1 interactor
STRINGi10090.ENSMUSP00000112283

PTM databases

iPTMnetiQ9JKF7
PhosphoSitePlusiQ9JKF7

Proteomic databases

EPDiQ9JKF7
MaxQBiQ9JKF7
PaxDbiQ9JKF7
PeptideAtlasiQ9JKF7
PRIDEiQ9JKF7

Protocols and materials databases

DNASUi27393
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000116584; ENSMUSP00000112283; ENSMUSG00000022889
GeneIDi27393
KEGGimmu:27393
UCSCiuc007zte.2 mouse

Organism-specific databases

CTDi54148
MGIiMGI:1351620 Mrpl39

Phylogenomic databases

eggNOGiKOG1637 Eukaryota
COG0441 LUCA
GeneTreeiENSGT00390000002149
HOGENOMiHOG000000683
HOVERGENiHBG023123
InParanoidiQ9JKF7
KOiK17420
OMAiPYNCAMH
OrthoDBiEOG091G0CTH
TreeFamiTF300858

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRSiMrpl39 mouse
PROiPR:Q9JKF7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022889 Expressed in 286 organ(s), highest expression level in testis
CleanExiMM_MRPL39
GenevisibleiQ9JKF7 MM

Family and domain databases

Gene3Di3.10.20.30, 1 hit
InterProiView protein in InterPro
IPR012675 Beta-grasp_dom_sf
IPR012676 TGS-like
IPR018163 Thr/Ala-tRNA-synth_IIc_edit
SUPFAMiSSF55186 SSF55186, 1 hit
SSF81271 SSF81271, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRM39_MOUSE
AccessioniPrimary (citable) accession number: Q9JKF7
Secondary accession number(s): A6X954, Q91YK5, Q9D8U5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: July 27, 2011
Last modified: September 12, 2018
This is version 146 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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