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Protein

Peroxisomal membrane protein 4

Gene

Pxmp4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein 4
Alternative name(s):
24 kDa peroxisomal intrinsic membrane protein
Gene namesi
Name:Pxmp4
Synonyms:Pmp24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1891701 Pxmp4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei97 – 117HelicalSequence analysisAdd BLAST21
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002189331 – 212Peroxisomal membrane protein 4Add BLAST212

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi206N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ9JJW0
PaxDbiQ9JJW0
PeptideAtlasiQ9JJW0
PRIDEiQ9JJW0

PTM databases

PhosphoSitePlusiQ9JJW0

Expressioni

Gene expression databases

BgeeiENSMUSG00000000876 Expressed in 215 organ(s), highest expression level in ear
CleanExiMM_PXMP4
ExpressionAtlasiQ9JJW0 baseline and differential
GenevisibleiQ9JJW0 MM

Interactioni

Subunit structurei

Interacts with PEX19.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000896

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IIYG Eukaryota
ENOG410ZE52 LUCA
GeneTreeiENSGT00390000001562
HOGENOMiHOG000157771
HOVERGENiHBG053773
InParanoidiQ9JJW0
KOiK13350
OMAiYTHSRNL
OrthoDBiEOG091G0K56
PhylomeDBiQ9JJW0
TreeFamiTF105313

Family and domain databases

InterProiView protein in InterPro
IPR019531 Pmp4
PANTHERiPTHR15460 PTHR15460, 1 hit
PIRSFiPIRSF013674 PXMP4, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9JJW0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPPQLQAL LQAVNKLLRQ RRYHAALAVI KGFRNGAVYG VKIRAPHALV
60 70 80 90 100
MTFLFRSGSL REKLQAILKA TYIHSRNLAC FVFAYKSLHA LQSHVQGETH
110 120 130 140 150
QMHSFLAAFI GGLLLFGENN NINSQINMYL TSRVLYALCR LGVEKGYIPA
160 170 180 190 200
LKWDPFPLHT AVIWGLVLWL FEYHRPTLQP SLQSSMTYLY EDSNVWHDLS
210
DFLIFNKSHP SK
Length:212
Mass (Da):24,196
Last modified:January 23, 2007 - v3
Checksum:i4C6FAC8BCB535417
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2AKD6A2AKD6_MOUSE
Peroxisomal membrane protein 4
Pxmp4
92Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271476 mRNA Translation: CAB71345.1
AK003127 mRNA No translation available.
AK019381 mRNA No translation available.
AK050647 mRNA Translation: BAC34361.1
AK156743 mRNA Translation: BAE33833.1
BC025796 mRNA Translation: AAH25796.1
CCDSiCCDS16936.1
RefSeqiNP_067509.1, NM_021534.3
UniGeneiMm.24673

Genome annotation databases

EnsembliENSMUST00000000896; ENSMUSP00000000896; ENSMUSG00000000876
GeneIDi59038
KEGGimmu:59038
UCSCiuc008njm.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271476 mRNA Translation: CAB71345.1
AK003127 mRNA No translation available.
AK019381 mRNA No translation available.
AK050647 mRNA Translation: BAC34361.1
AK156743 mRNA Translation: BAE33833.1
BC025796 mRNA Translation: AAH25796.1
CCDSiCCDS16936.1
RefSeqiNP_067509.1, NM_021534.3
UniGeneiMm.24673

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000896

PTM databases

PhosphoSitePlusiQ9JJW0

Proteomic databases

MaxQBiQ9JJW0
PaxDbiQ9JJW0
PeptideAtlasiQ9JJW0
PRIDEiQ9JJW0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000000896; ENSMUSP00000000896; ENSMUSG00000000876
GeneIDi59038
KEGGimmu:59038
UCSCiuc008njm.1 mouse

Organism-specific databases

CTDi11264
MGIiMGI:1891701 Pxmp4

Phylogenomic databases

eggNOGiENOG410IIYG Eukaryota
ENOG410ZE52 LUCA
GeneTreeiENSGT00390000001562
HOGENOMiHOG000157771
HOVERGENiHBG053773
InParanoidiQ9JJW0
KOiK13350
OMAiYTHSRNL
OrthoDBiEOG091G0K56
PhylomeDBiQ9JJW0
TreeFamiTF105313

Miscellaneous databases

PROiPR:Q9JJW0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000000876 Expressed in 215 organ(s), highest expression level in ear
CleanExiMM_PXMP4
ExpressionAtlasiQ9JJW0 baseline and differential
GenevisibleiQ9JJW0 MM

Family and domain databases

InterProiView protein in InterPro
IPR019531 Pmp4
PANTHERiPTHR15460 PTHR15460, 1 hit
PIRSFiPIRSF013674 PXMP4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPXMP4_MOUSE
AccessioniPrimary (citable) accession number: Q9JJW0
Secondary accession number(s): Q3U0L9, Q9CQV9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 28, 2003
Last sequence update: January 23, 2007
Last modified: September 12, 2018
This is version 111 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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