Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 138 (08 May 2019)
Sequence version 3 (05 Feb 2008)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

RNA binding protein fox-1 homolog 1

Gene

Rbfox1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processmRNA processing, mRNA splicing

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA binding protein fox-1 homolog 1
Alternative name(s):
Ataxin-2-binding protein 1
Fox-1 homolog A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rbfox1
Synonyms:A2bp, A2bp1, Fox1
ORF Names:MNCb-3035
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1926224 Rbfox1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000814811 – 396RNA binding protein fox-1 homolog 1Add BLAST396

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei316Asymmetric dimethylarginineCombined sources1
Modified residuei387Omega-N-methylarginineCombined sources1
Isoform 3 (identifier: Q9JJ43-3)
Modified residuei337Asymmetric dimethylarginineCombined sources1

Keywords - PTMi

Methylation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9JJ43

PeptideAtlas

More...
PeptideAtlasi
Q9JJ43

PRoteomics IDEntifications database

More...
PRIDEi
Q9JJ43

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9JJ43

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9JJ43

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in brain (at protein level). Detected in heart, brain, neurons, skeletal muscle and embryo.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000008658 Expressed in 199 organ(s), highest expression level in caudate-putamen

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9JJ43 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9JJ43 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the C-terminus of ATXN2.

By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei117Interaction with RNABy similarity1
Sitei125Interaction with RNABy similarity1
Sitei126Interaction with RNABy similarity1
Sitei150Interaction with RNABy similarity1
Sitei155Interaction with RNABy similarity1
Sitei159Interaction with RNABy similarity1
Sitei183Interaction with RNABy similarity1
Sitei193Interaction with RNABy similarity1

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
234568, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q9JJ43, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9JJ43

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000049970

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini116 – 192RRMPROSITE-ProRule annotationAdd BLAST77

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0125 Eukaryota
ENOG4111WJT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160685

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9JJ43

KEGG Orthology (KO)

More...
KOi
K14946

Identification of Orthologs from Complete Genome Data

More...
OMAi
EHTLNMY

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9JJ43

TreeFam database of animal gene trees

More...
TreeFami
TF315942

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12407 RRM_FOX1_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025670 Fox-1_C_dom
IPR034237 FOX1_RRM
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR017325 RNA-bd_Fox-1
IPR000504 RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12414 Fox-1_C, 1 hit
PF00076 RRM_1, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037932 Ataxin_2_bd_A2BP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 7 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 7 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9JJ43-1) [UniParc]FASTAAdd to basket
Also known as: A016

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNCEREQLRG NQEAAAAPDT MAQPYASAQF APPQNGIPAE YTAPHPHPAP
60 70 80 90 100
EYTGQTTVPD HTLNLYPPTQ THSEQSADTS AQTVSGTATQ TDDAAPTDGQ
110 120 130 140 150
PQTQPSENTE SKSQPKRLHV SNIPFRFRDP DLRQMFGQFG KILDVEIIFN
160 170 180 190 200
ERGSKGFGFV TFENSADADR AREKLHGTVV EGRKIEVNNA TARVMTNKKT
210 220 230 240 250
VNPYTNGWKL NPVVGAVYSP DFYAGTVLLC QANQEGSSMY SGPSSLVYTS
260 270 280 290 300
AMPGFPYPAA TAAAAYRGAH LRGRGRTVYN TFRAAAPPPP IPAYGGVVYQ
310 320 330 340 350
DGFYGADIYG GYAAYRYAQP TPATAAAYSD SYGRVYAADP YHHTLAPAPT
360 370 380 390
YGVGAMNAFA PLTDAKTRSH ADDVGLVLSS LQASIYRGGY NRFAPY
Length:396
Mass (Da):42,678
Last modified:February 5, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE64DBA6FE6A062ED
GO
Isoform 2 (identifier: Q9JJ43-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-20: Missing.

Show »
Length:376
Mass (Da):40,492
Checksum:i77C56FE98817B9F2
GO
Isoform 3 (identifier: Q9JJ43-3) [UniParc]FASTAAdd to basket
Also known as: A713

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: MNCEREQLR → MLASQGVLLHSYGVPMIVPAAPYFPGLMQ
     301-309: DGFYGADIY → EPVYGNKLLQ

Show »
Length:417
Mass (Da):44,729
Checksum:i95D41CFA0A1D5535
GO
Isoform 4 (identifier: Q9JJ43-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     207-224: Missing.

Show »
Length:378
Mass (Da):40,713
Checksum:i966076D6E685A9C6
GO
Isoform 5 (identifier: Q9JJ43-5) [UniParc]FASTAAdd to basket
Also known as: 2, A030

The sequence of this isoform differs from the canonical sequence as follows:
     331-396: SYGRVYAADP...RGGYNRFAPY → RNQFVFVATD...LQPPPTALVP

Show »
Length:373
Mass (Da):40,288
Checksum:iC20687C2777B463C
GO
Isoform 6 (identifier: Q9JJ43-6) [UniParc]FASTAAdd to basket
Also known as: 4, A715

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: MNCEREQLR → MLASQGVLLHSYGVPMIVPAAPYFPGLMQ
     301-309: DGFYGADIY → EPVYGNKLLQ
     331-396: SYGRVYAADP...RGGYNRFAPY → RNQFVFVATD...LQPPPTALVP

Show »
Length:394
Mass (Da):42,338
Checksum:i905CCB2924E570F4
GO
Isoform 7 (identifier: Q9JJ43-7) [UniParc]FASTAAdd to basket
Also known as: 5, A704

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: MNCEREQLR → MLASQGVLLHSYGVPMIVPAAPYFPGLMQ
     156-186: Missing.
     301-309: DGFYGADIY → EPVYGNKLLQ
     331-396: SYGRVYAADP...RGGYNRFAPY → RNQFVFVATD...LQPPPTALVP

Show »
Length:363
Mass (Da):38,919
Checksum:iE8A44FBE429F8741
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8VK79A0A2R8VK79_MOUSE
RNA binding protein fox-1 homolog
Rbfox1
396Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8VI79A0A2R8VI79_MOUSE
RNA binding protein fox-1 homolog
Rbfox1
358Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8W6K5A0A2R8W6K5_MOUSE
RNA-binding protein fox-1 homolog 1
Rbfox1
289Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8VHB5A0A2R8VHB5_MOUSE
RNA-binding protein fox-1 homolog 1
Rbfox1
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti60D → G in BAA95079 (Ref. 4) Curated1
Sequence conflicti124P → PFR in AAF78292 (PubMed:10814712).Curated1
Sequence conflicti136F → FS in AAF78292 (PubMed:10814712).Curated1
Sequence conflicti261T → S in AAL83425 (Ref. 3) Curated1
Sequence conflicti278V → G in AAL83425 (Ref. 3) Curated1
Sequence conflicti282F → L in AAL83425 (Ref. 3) Curated1
Sequence conflicti369S → G in BAA95079 (Ref. 4) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0308791 – 20Missing in isoform 2. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_0308801 – 9MNCEREQLR → MLASQGVLLHSYGVPMIVPA APYFPGLMQ in isoform 3, isoform 6 and isoform 7. 3 Publications9
Alternative sequenceiVSP_030881156 – 186Missing in isoform 7. 1 PublicationAdd BLAST31
Alternative sequenceiVSP_030882207 – 224Missing in isoform 4. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_030883301 – 309DGFYGADIY → EPVYGNKLLQ in isoform 3, isoform 6 and isoform 7. 3 Publications9
Alternative sequenceiVSP_030884331 – 396SYGRV…RFAPY → RNQFVFVATDEISCNTSAVT DEFMLPTPTTTHLLQPPPTA LVP in isoform 5, isoform 6 and isoform 7. 3 PublicationsAdd BLAST66

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF107204 mRNA Translation: AAF78292.1
AY659954 mRNA Translation: AAV74337.1
AY659955 mRNA Translation: AAV74338.1
AY659956 mRNA Translation: AAV74339.1
AY659957 mRNA Translation: AAV74340.1
AY659958 mRNA Translation: AAV74341.1
AF191501 mRNA Translation: AAL83425.1
AB041596 mRNA Translation: BAA95079.1
AK134833 mRNA Translation: BAE22304.1
BC059002 mRNA Translation: AAH59002.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS27936.1 [Q9JJ43-3]
CCDS37245.1 [Q9JJ43-1]

NCBI Reference Sequences

More...
RefSeqi
NP_067452.2, NM_021477.5 [Q9JJ43-1]
NP_899011.2, NM_183188.2 [Q9JJ43-3]
XP_006522251.1, XM_006522188.1
XP_006522252.1, XM_006522189.3 [Q9JJ43-6]
XP_006522253.1, XM_006522190.1 [Q9JJ43-4]
XP_006522255.1, XM_006522192.3 [Q9JJ43-2]
XP_011244213.1, XM_011245911.2 [Q9JJ43-1]
XP_011244218.1, XM_011245916.1 [Q9JJ43-5]
XP_017172487.1, XM_017316998.1
XP_017172491.1, XM_017317002.1 [Q9JJ43-5]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000056416; ENSMUSP00000049970; ENSMUSG00000008658 [Q9JJ43-1]
ENSMUST00000115841; ENSMUSP00000111507; ENSMUSG00000008658 [Q9JJ43-1]
ENSMUST00000229741; ENSMUSP00000155364; ENSMUSG00000008658 [Q9JJ43-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
268859

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:268859

UCSC genome browser

More...
UCSCi
uc007ycb.2 mouse [Q9JJ43-1]
uc007ycc.2 mouse [Q9JJ43-4]
uc007ycf.2 mouse [Q9JJ43-3]
uc007ycg.2 mouse [Q9JJ43-6]
uc007ych.2 mouse [Q9JJ43-7]
uc007yci.2 mouse [Q9JJ43-5]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF107204 mRNA Translation: AAF78292.1
AY659954 mRNA Translation: AAV74337.1
AY659955 mRNA Translation: AAV74338.1
AY659956 mRNA Translation: AAV74339.1
AY659957 mRNA Translation: AAV74340.1
AY659958 mRNA Translation: AAV74341.1
AF191501 mRNA Translation: AAL83425.1
AB041596 mRNA Translation: BAA95079.1
AK134833 mRNA Translation: BAE22304.1
BC059002 mRNA Translation: AAH59002.1
CCDSiCCDS27936.1 [Q9JJ43-3]
CCDS37245.1 [Q9JJ43-1]
RefSeqiNP_067452.2, NM_021477.5 [Q9JJ43-1]
NP_899011.2, NM_183188.2 [Q9JJ43-3]
XP_006522251.1, XM_006522188.1
XP_006522252.1, XM_006522189.3 [Q9JJ43-6]
XP_006522253.1, XM_006522190.1 [Q9JJ43-4]
XP_006522255.1, XM_006522192.3 [Q9JJ43-2]
XP_011244213.1, XM_011245911.2 [Q9JJ43-1]
XP_011244218.1, XM_011245916.1 [Q9JJ43-5]
XP_017172487.1, XM_017316998.1
XP_017172491.1, XM_017317002.1 [Q9JJ43-5]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi234568, 2 interactors
IntActiQ9JJ43, 2 interactors
MINTiQ9JJ43
STRINGi10090.ENSMUSP00000049970

PTM databases

iPTMnetiQ9JJ43
PhosphoSitePlusiQ9JJ43

Proteomic databases

PaxDbiQ9JJ43
PeptideAtlasiQ9JJ43
PRIDEiQ9JJ43

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000056416; ENSMUSP00000049970; ENSMUSG00000008658 [Q9JJ43-1]
ENSMUST00000115841; ENSMUSP00000111507; ENSMUSG00000008658 [Q9JJ43-1]
ENSMUST00000229741; ENSMUSP00000155364; ENSMUSG00000008658 [Q9JJ43-3]
GeneIDi268859
KEGGimmu:268859
UCSCiuc007ycb.2 mouse [Q9JJ43-1]
uc007ycc.2 mouse [Q9JJ43-4]
uc007ycf.2 mouse [Q9JJ43-3]
uc007ycg.2 mouse [Q9JJ43-6]
uc007ych.2 mouse [Q9JJ43-7]
uc007yci.2 mouse [Q9JJ43-5]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54715
MGIiMGI:1926224 Rbfox1

Phylogenomic databases

eggNOGiKOG0125 Eukaryota
ENOG4111WJT LUCA
GeneTreeiENSGT00940000160685
InParanoidiQ9JJ43
KOiK14946
OMAiEHTLNMY
PhylomeDBiQ9JJ43
TreeFamiTF315942

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rbfox1 mouse

Protein Ontology

More...
PROi
PR:Q9JJ43

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000008658 Expressed in 199 organ(s), highest expression level in caudate-putamen
ExpressionAtlasiQ9JJ43 baseline and differential
GenevisibleiQ9JJ43 MM

Family and domain databases

CDDicd12407 RRM_FOX1_like, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR025670 Fox-1_C_dom
IPR034237 FOX1_RRM
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR017325 RNA-bd_Fox-1
IPR000504 RRM_dom
PfamiView protein in Pfam
PF12414 Fox-1_C, 1 hit
PF00076 RRM_1, 1 hit
PIRSFiPIRSF037932 Ataxin_2_bd_A2BP, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRFOX1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9JJ43
Secondary accession number(s): Q3UYA8
, Q537C9, Q537D0, Q537D1, Q537D2, Q6PD12, Q8R4Z7, Q9JJB5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 5, 2008
Last modified: May 8, 2019
This is version 138 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again