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Protein
Submitted name:

Activator protein 4

Gene

Tfap4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Activator protein 4Imported
Submitted name:
Transcription factor AP4Imported
Gene namesi
Name:Tfap4Imported
Synonyms:Ap4Imported, Tcfap4Imported
ORF Names:mCG_128721Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:103239 Tfap4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000005718 Expressed in 141 organ(s), highest expression level in telencephalon ventricular layer (mouse)

Interactioni

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-59708N
IntActiQ9JIZ5, 6 interactors
Q9JIZ5, 6 interactors
STRINGi10090.ENSMUSP00000005862

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 99BHLHInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili99 – 119Sequence analysisAdd BLAST21
Coiled coili148 – 182Sequence analysisAdd BLAST35
Coiled coili197 – 217Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0561 Eukaryota
ENOG4111JPE LUCA
GeneTreeiENSGT00390000015189
HOGENOMiHOG000294087
HOVERGENiHBG061473
KOiK09108
OMAiHHVNVVT
OrthoDBiEOG091G194I
TreeFamiTF316489

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9JIZ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEYFMVPTQK VPSLQHFRKT EKEVIGGLCS LANIPLTPET QRDQERRIRR
60 70 80 90 100
EIANSNERRR MQSINAGFQS LKTLIPHTDG EKLSKAAILQ QTAEYIFSLE
110 120 130 140 150
QEKTRLLQQN TQLKRFIQEL SGSSPKRRRA EDKDEGIGSP DIWEDEKAED
160 170 180 190 200
LRREMIELRQ QLDKERSVRM MLEEQVRSLE AHMYPEKLKV IAQQVQLQQQ
210 220 230 240 250
QEQVRLLHQE KLEREQQHLR TQLLPPPAPT HHPTVIVPAP APPSSHHINV
260 270 280 290 300
VTMGPSSVIN SVSTSRQNLD TIVQAIQHIE GTQDKQELEE EQRRAVIVKS
310 320 330
VRSCPDAHTS DTASDSEASD SDAMDQSREE PLGDGELP
Length:338
Mass (Da):38,727
Last modified:October 1, 2000 - v1
Checksum:iFDCF2C4FBD38D29B
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8W6R9A0A2R8W6R9_MOUSE
Transcription factor AP4
Tfap4
199Annotation score:
A0A2R8VI80A0A2R8VI80_MOUSE
Transcription factor AP4
Tfap4
214Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157597 Genomic DNA No translation available.
AF161262 mRNA Translation: AAF80448.1
BC047270 mRNA Translation: AAH47270.1
BC054777 mRNA Translation: AAH54777.1
AK166424 mRNA Translation: BAE38767.1
CH466521 Genomic DNA Translation: EDK97233.1
RefSeqiNP_112459.1, NM_031182.2
UniGeneiMm.273210

Genome annotation databases

EnsembliENSMUST00000005862; ENSMUSP00000005862; ENSMUSG00000005718
GeneIDi83383
KEGGimmu:83383
UCSCiuc007xzv.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157597 Genomic DNA No translation available.
AF161262 mRNA Translation: AAF80448.1
BC047270 mRNA Translation: AAH47270.1
BC054777 mRNA Translation: AAH54777.1
AK166424 mRNA Translation: BAE38767.1
CH466521 Genomic DNA Translation: EDK97233.1
RefSeqiNP_112459.1, NM_031182.2
UniGeneiMm.273210

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59708N
IntActiQ9JIZ5, 6 interactors
Q9JIZ5, 6 interactors
STRINGi10090.ENSMUSP00000005862

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000005862; ENSMUSP00000005862; ENSMUSG00000005718
GeneIDi83383
KEGGimmu:83383
UCSCiuc007xzv.1 mouse

Organism-specific databases

CTDi7023
MGIiMGI:103239 Tfap4

Phylogenomic databases

eggNOGiKOG0561 Eukaryota
ENOG4111JPE LUCA
GeneTreeiENSGT00390000015189
HOGENOMiHOG000294087
HOVERGENiHBG061473
KOiK09108
OMAiHHVNVVT
OrthoDBiEOG091G194I
TreeFamiTF316489

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000005718 Expressed in 141 organ(s), highest expression level in telencephalon ventricular layer (mouse)

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9JIZ5_MOUSE
AccessioniPrimary (citable) accession number: Q9JIZ5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: November 7, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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