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Protein

RING finger protein 32

Gene

Rnf32

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in sperm formation.

Miscellaneous

No coding region alterations in either Hemimelic extra-toes (Hx) or Hammertoe (Hm) mutant mice was detected.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri129 – 171RING-type 1; atypicalPROSITE-ProRule annotationAdd BLAST43
Zinc fingeri295 – 358RING-type 2; atypicalPROSITE-ProRule annotationAdd BLAST64

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RING finger protein 32
Alternative name(s):
Limb region protein 2
Gene namesi
Name:Rnf32
Synonyms:Lmbr2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1861747 Rnf32

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002455341 – 368RING finger protein 32Add BLAST368

Proteomic databases

PaxDbiQ9JIT1
PRIDEiQ9JIT1

PTM databases

iPTMnetiQ9JIT1
PhosphoSitePlusiQ9JIT1

Expressioni

Gene expression databases

BgeeiENSMUSG00000029130 Expressed in 198 organ(s), highest expression level in testis
CleanExiMM_RNF32
ExpressionAtlasiQ9JIT1 baseline and differential
GenevisibleiQ9JIT1 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001247

Structurei

3D structure databases

ProteinModelPortaliQ9JIT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini188 – 217IQPROSITE-ProRule annotationAdd BLAST30

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri129 – 171RING-type 1; atypicalPROSITE-ProRule annotationAdd BLAST43
Zinc fingeri295 – 358RING-type 2; atypicalPROSITE-ProRule annotationAdd BLAST64

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG0800 Eukaryota
ENOG41121N2 LUCA
GeneTreeiENSGT00390000003759
HOGENOMiHOG000007992
HOVERGENiHBG082459
InParanoidiQ9JIT1
OMAiYETRVIH
OrthoDBiEOG091G0AGY
PhylomeDBiQ9JIT1
TreeFamiTF329796

Family and domain databases

Gene3Di3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR027370 Znf-RING_LisH
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00612 IQ, 1 hit
PF13639 zf-RING_2, 1 hit
PF13445 zf-RING_UBOX, 1 hit
SMARTiView protein in SMART
SM00184 RING, 2 hits
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS50089 ZF_RING_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q9JIT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRNKDRSSN KGNLAVTAVA LQDHLLHDLQ LGHLSVADPC KIKARKKEKK
60 70 80 90 100
SKSLKRDATA IIDTGLRKST EGPNMEDPEK EYVLDPTPPP LTLAQKLGLL
110 120 130 140 150
PPPPLPLSSD EWERVKQRSL LQGDSIQPCP ICKEEFELHP QVLLSCSHVF
160 170 180 190 200
HRACLQAFEK FTNKKTCPLC RKNQYQTRVI HDGARLFRVK CATRIQAYWR
210 220 230 240 250
GYIVRKWYRN LRKIIPPSDA KLRRKFFEEK FTEISHRILC SYNTNIDELF
260 270 280 290 300
SEIDVCLAVN RSILQQLDER CGQIITKEDW EKIQAQAAHH EIYECSICLT
310 320 330 340 350
PLSFHGDGRQ AAIGTSSQRP RETVLLSCAH LFHNACLLAL EEFSLGDNAP
360
FHVCPLCRSC YQKKIVEC
Length:368
Mass (Da):42,139
Last modified:October 1, 2000 - v1
Checksum:i23F8DE23EF4D02AC
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6URG7F6URG7_MOUSE
RING finger protein 32
Rnf32
275Annotation score:
E0CY41E0CY41_MOUSE
RING finger protein 32
Rnf32
120Annotation score:
E0CZ33E0CZ33_MOUSE
RING finger protein 32
Rnf32
123Annotation score:
E0CY22E0CY22_MOUSE
RING finger protein 32
Rnf32
46Annotation score:
E0CZC4E0CZC4_MOUSE
RING finger protein 32
Rnf32 mCG_7344
103Annotation score:
A0A0J9YUY1A0A0J9YUY1_MOUSE
RING finger protein 32
Rnf32
29Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti84L → I in BAB24557 (PubMed:16141072).Curated1
Sequence conflicti99L → I in BAB24557 (PubMed:16141072).Curated1
Sequence conflicti113E → G in BAB24242 (PubMed:16141072).Curated1
Sequence conflicti123G → R in BAB24242 (PubMed:16141072).Curated1
Sequence conflicti245N → K in BAB24557 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF190664 mRNA Translation: AAF91091.1
AK005795 mRNA Translation: BAB24242.1
AK006379 mRNA Translation: BAB24557.1
BC089493 mRNA Translation: AAH89493.1
CCDSiCCDS39041.1
RefSeqiNP_001276686.1, NM_001289757.1
NP_067445.3, NM_021470.6
XP_006535838.1, XM_006535775.3
XP_006535839.1, XM_006535776.3
XP_006535840.1, XM_006535777.3
XP_006535841.1, XM_006535778.3
XP_006535842.1, XM_006535779.3
XP_006535843.1, XM_006535780.2
XP_006535844.1, XM_006535781.3
UniGeneiMm.487302
Mm.87352

Genome annotation databases

EnsembliENSMUST00000001247; ENSMUSP00000001247; ENSMUSG00000029130
ENSMUST00000160246; ENSMUSP00000124657; ENSMUSG00000029130
ENSMUST00000168460; ENSMUSP00000132213; ENSMUSG00000029130
GeneIDi56874
KEGGimmu:56874
UCSCiuc008wuc.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF190664 mRNA Translation: AAF91091.1
AK005795 mRNA Translation: BAB24242.1
AK006379 mRNA Translation: BAB24557.1
BC089493 mRNA Translation: AAH89493.1
CCDSiCCDS39041.1
RefSeqiNP_001276686.1, NM_001289757.1
NP_067445.3, NM_021470.6
XP_006535838.1, XM_006535775.3
XP_006535839.1, XM_006535776.3
XP_006535840.1, XM_006535777.3
XP_006535841.1, XM_006535778.3
XP_006535842.1, XM_006535779.3
XP_006535843.1, XM_006535780.2
XP_006535844.1, XM_006535781.3
UniGeneiMm.487302
Mm.87352

3D structure databases

ProteinModelPortaliQ9JIT1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001247

PTM databases

iPTMnetiQ9JIT1
PhosphoSitePlusiQ9JIT1

Proteomic databases

PaxDbiQ9JIT1
PRIDEiQ9JIT1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000001247; ENSMUSP00000001247; ENSMUSG00000029130
ENSMUST00000160246; ENSMUSP00000124657; ENSMUSG00000029130
ENSMUST00000168460; ENSMUSP00000132213; ENSMUSG00000029130
GeneIDi56874
KEGGimmu:56874
UCSCiuc008wuc.2 mouse

Organism-specific databases

CTDi140545
MGIiMGI:1861747 Rnf32

Phylogenomic databases

eggNOGiKOG0800 Eukaryota
ENOG41121N2 LUCA
GeneTreeiENSGT00390000003759
HOGENOMiHOG000007992
HOVERGENiHBG082459
InParanoidiQ9JIT1
OMAiYETRVIH
OrthoDBiEOG091G0AGY
PhylomeDBiQ9JIT1
TreeFamiTF329796

Miscellaneous databases

ChiTaRSiRnf32 mouse
PROiPR:Q9JIT1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029130 Expressed in 198 organ(s), highest expression level in testis
CleanExiMM_RNF32
ExpressionAtlasiQ9JIT1 baseline and differential
GenevisibleiQ9JIT1 MM

Family and domain databases

Gene3Di3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR027370 Znf-RING_LisH
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00612 IQ, 1 hit
PF13639 zf-RING_2, 1 hit
PF13445 zf-RING_UBOX, 1 hit
SMARTiView protein in SMART
SM00184 RING, 2 hits
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS50089 ZF_RING_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiRNF32_MOUSE
AccessioniPrimary (citable) accession number: Q9JIT1
Secondary accession number(s): Q9D9X0, Q9DAJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: October 1, 2000
Last modified: November 7, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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