Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Otoraplin

Gene

Otor

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • cartilage condensation Source: MGI

Names & Taxonomyi

Protein namesi
Recommended name:
Otoraplin
Alternative name(s):
Melanoma inhibitory activity-like protein
Gene namesi
Name:Otor
Synonyms:Mial
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1888678 Otor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000001903419 – 128OtoraplinAdd BLAST110

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi32 ↔ 37By similarity
Disulfide bondi55 ↔ 127By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ9JIE3
PRIDEiQ9JIE3

PTM databases

PhosphoSitePlusiQ9JIE3

Expressioni

Tissue specificityi

Highly expressed in cochlea.

Gene expression databases

BgeeiENSMUSG00000027416 Expressed in 63 organ(s), highest expression level in stria vascularis of cochlear duct
CleanExiMM_OTOR
ExpressionAtlasiQ9JIE3 baseline and differential
GenevisibleiQ9JIE3 MM

Structurei

3D structure databases

ProteinModelPortaliQ9JIE3
SMRiQ9JIE3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 110SH3PROSITE-ProRule annotationAdd BLAST72

Sequence similaritiesi

Belongs to the MIA/OTOR family.Curated

Keywords - Domaini

SH3 domain, Signal

Phylogenomic databases

eggNOGiENOG410IY1J Eukaryota
ENOG4111P4M LUCA
GeneTreeiENSGT00390000010535
HOGENOMiHOG000063668
HOVERGENiHBG000503
InParanoidiQ9JIE3
OMAiMGTVGYF
OrthoDBiEOG091G0RVX
PhylomeDBiQ9JIE3
TreeFamiTF332724

Family and domain databases

CDDicd11891 MIAL, 1 hit
InterProiView protein in InterPro
IPR035554 Otoraplin_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9JIE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARILILLLG GLVVLCAGHG VFMDKLSSKK LCADEECVYT ISLARAQEDY
60 70 80 90 100
NAPDCRFIDV KKGQQIYVYS KLVTENGAGE FWAGSVYGDH QDEMGIVGYF
110 120
PSNLVKEQRV YQEATKEIPT TDIDFFCE
Length:128
Mass (Da):14,328
Last modified:October 1, 2000 - v1
Checksum:i3DD47D4C77C4A7FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF233333 mRNA Translation: AAF82079.1
AJ243939 mRNA Translation: CAC27444.1
CCDSiCCDS16809.1
RefSeqiNP_065620.1, NM_020595.3
UniGeneiMm.157751

Genome annotation databases

EnsembliENSMUST00000028902; ENSMUSP00000028902; ENSMUSG00000027416
GeneIDi57329
KEGGimmu:57329
UCSCiuc008mqc.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF233333 mRNA Translation: AAF82079.1
AJ243939 mRNA Translation: CAC27444.1
CCDSiCCDS16809.1
RefSeqiNP_065620.1, NM_020595.3
UniGeneiMm.157751

3D structure databases

ProteinModelPortaliQ9JIE3
SMRiQ9JIE3
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSitePlusiQ9JIE3

Proteomic databases

PaxDbiQ9JIE3
PRIDEiQ9JIE3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000028902; ENSMUSP00000028902; ENSMUSG00000027416
GeneIDi57329
KEGGimmu:57329
UCSCiuc008mqc.1 mouse

Organism-specific databases

CTDi56914
MGIiMGI:1888678 Otor

Phylogenomic databases

eggNOGiENOG410IY1J Eukaryota
ENOG4111P4M LUCA
GeneTreeiENSGT00390000010535
HOGENOMiHOG000063668
HOVERGENiHBG000503
InParanoidiQ9JIE3
OMAiMGTVGYF
OrthoDBiEOG091G0RVX
PhylomeDBiQ9JIE3
TreeFamiTF332724

Miscellaneous databases

PROiPR:Q9JIE3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027416 Expressed in 63 organ(s), highest expression level in stria vascularis of cochlear duct
CleanExiMM_OTOR
ExpressionAtlasiQ9JIE3 baseline and differential
GenevisibleiQ9JIE3 MM

Family and domain databases

CDDicd11891 MIAL, 1 hit
InterProiView protein in InterPro
IPR035554 Otoraplin_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiOTOR_MOUSE
AccessioniPrimary (citable) accession number: Q9JIE3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: October 1, 2000
Last modified: November 7, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again