UniProtKB - Q9I9C5 (Q9I9C5_CHICK)
Protein
Submitted name:
Iroquois homologue-1
Gene
irx1
Organism
Gallus gallus (Chicken)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 133 – 185 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 53 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Iroquois homologue-1Imported |
Gene namesi | Name:irx1Imported |
Organismi | Gallus gallus (Chicken)Imported |
Taxonomic identifieri | 9031 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 131 – 184 | HomeoboxInterPro annotationAdd BLAST | 54 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 184 – 304 | DisorderedSequence analysisAdd BLAST | 121 | |
Regioni | 412 – 467 | DisorderedSequence analysisAdd BLAST | 56 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 184 – 208 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 209 – 241 | AcidicSequence analysisAdd BLAST | 33 | |
Compositional biasi | 242 – 268 | PolyampholyteSequence analysisAdd BLAST | 27 | |
Compositional biasi | 285 – 304 | PolarSequence analysisAdd BLAST | 20 | |
Compositional biasi | 443 – 461 | PolarSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Belongs to the TALE/IRO homeobox family.ARBA annotation
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationARBA annotationPhylogenomic databases
PhylomeDBi | Q9I9C5 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR008422, Homeobox_KN_domain IPR003893, Iroquois_homeo IPR006311, TAT_signal |
Pfami | View protein in Pfam PF05920, Homeobox_KN, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00548, IRO, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit PS51318, TAT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9I9C5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSFPQLGYPQ YLSASQAVYG SERPGVLAAA AAAAAAAAAA SGRPAGAELG
60 70 80 90 100
SGSAAVTSVL GMYAGPYSAP NYSAFLPYTA DLGLFSQMGS QYELKDNPGV
110 120 130 140 150
HPATFAAHTA PGYYPYGQFQ YGDPGRPKNA TRESTSTLKA WLNEHRKNPY
160 170 180 190 200
PTKGEKIMLA IITKMTLTQV STWFANARRR LKKENKVTWG SRSKDQEDAN
210 220 230 240 250
LFGSDNEGDP EKTEDDEEID LESIDIDKID ENDGEQSNEE EEEKPELLRQ
260 270 280 290 300
SSEEERLEKD KELSLSGSEG LKPKDALAMV KEASDNSTRI ISPGGQSNLQ
310 320 330 340 350
MPSHSKPKIW SLAETATSPD GALKSSPPPP PPAQVTHTLP QIQHPAFLPS
360 370 380 390 400
HGLYTCQIGK FHNWTNGAFL TQSSLLNVRS FLGVNHHHAT HHNHHLQAQQ
410 420 430 440 450
QPSVLTATLG ALSSEKPSER TSPKHIENVP RTDSPPQPLK SPFQPVRDNS
460
LPQQEGTPRI LTALPSA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ238354 mRNA Translation: CAB89806.1 |
RefSeqi | NP_001025509.1, NM_001030338.1 |
Genome annotation databases
GeneIDi | 374185 |
KEGGi | gga:374185 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ238354 mRNA Translation: CAB89806.1 |
RefSeqi | NP_001025509.1, NM_001030338.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 374185 |
KEGGi | gga:374185 |
Organism-specific databases
CTDi | 79192 |
Phylogenomic databases
PhylomeDBi | Q9I9C5 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR008422, Homeobox_KN_domain IPR003893, Iroquois_homeo IPR006311, TAT_signal |
Pfami | View protein in Pfam PF05920, Homeobox_KN, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00548, IRO, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit PS51318, TAT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9I9C5_CHICK | |
Accessioni | Q9I9C5Primary (citable) accession number: Q9I9C5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2000 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |