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UniProtKB - Q9I920 (BLM_CHICK)

Entry version 116 (02 Dec 2020)
Sequence version 2 (27 Sep 2017)
Previous versions | rss
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Protein

Bloom syndrome protein homolog

Gene

BLM

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction (PubMed:28228481). Participates in DNA replication and repair (By similarity). Involved in 5'-end resection of DNA during double-strand break (DSB) repair (By similarity). Negatively regulates sister chromatid exchange (SCE) (By similarity). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution (By similarity). Binds DNA (PubMed:28228481). Binds single-stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei4883' overhang DNA-bindingBy similarity1
Sitei5793' overhang DNA-bindingBy similarity1
Sitei6913' overhang DNA-binding; via amide nitrogenBy similarity1
Sitei7173' overhang DNA-bindingBy similarity1
Sitei7393' overhang DNA-bindingBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei753ATPBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi807ZincBy similarity1
Metal bindingi826ZincBy similarity1
Metal bindingi834ZincBy similarity1
Metal bindingi837ZincBy similarity1
Sitei8813' overhang DNA-bindingBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi439 – 443ATPBy similarity5
Nucleotide bindingi463 – 467ATPBy similarity5

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Helicase, Hydrolase
Biological processDNA damage, DNA repair, DNA replication
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bloom syndrome protein homolog (EC:3.6.4.121 Publication)
Alternative name(s):
RecQ helicase homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BLM
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002050411 – 1183Bloom syndrome protein homologAdd BLAST1183

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9I920

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer (PubMed:28228481). Homodimer (via N-terminus) (PubMed:28228481). Homotetramer (via N-terminus); dimer of dimers (PubMed:28228481). Homohexamer (via N-terminus) (PubMed:28228481). Self-association negatively regulates DNA unwinding amplitude and rate (PubMed:28228481). Oligomer complexes dissociate into monomer in presence of ATP (PubMed:28228481).

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9031.ENSGALP00000013422

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11183
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9I920

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini447 – 622Helicase ATP-bindingPROSITE-ProRule annotationBy similarityAdd BLAST176
Domaini648 – 795Helicase C-terminalPROSITE-ProRule annotationBy similarityAdd BLAST148
Domaini983 – 1063HRDCPROSITE-ProRule annotationBy similarityAdd BLAST81

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni110 – 162Necessary for dimerization and homooligomerization1 PublicationAdd BLAST53
Regioni641 – 6443' overhang DNA-bindingBy similarity4
Regioni668 – 6703' overhang DNA-bindingBy similarity3
Regioni771 – 7743' overhang DNA-bindingBy similarity4
Regioni865 – 910DNA Holliday junction bindingBy similarityAdd BLAST46
Regioni881 – 8833' overhang DNA-bindingBy similarity3
Regioni892 – 8963' overhang DNA-bindingBy similarity5
Regioni931 – 9373' overhang DNA-bindingBy similarity7
Regioni998 – 1015Necessary for ssDNA and DNA Holliday junction bindingBy similarityAdd BLAST18

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi566 – 569DEAH box4
Motifi1104 – 1120Nuclear localization signalBy similarityAdd BLAST17

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal region mediates dimerization and homooligomerization (PubMed:28228481). Both the helicase ATP-binding domain and the helicase C-terminal domain form intramolecular interactions with the HRDC domain in a ATP-dependent manner (By similarity). The HRDC domain is required for single-stranded DNA (ssDNA) and DNA Holliday junction binding (By similarity).By similarity1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the helicase family. RecQ subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0351, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9I920

Database of Orthologous Groups

More...OrthoDBi		445763at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012532, BDHCT
IPR032437, BLM_N
IPR011545, DEAD/DEAH_box_helicase_dom
IPR002464, DNA/RNA_helicase_DEAH_CS
IPR004589, DNA_helicase_ATP-dep_RecQ
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR010997, HRDC-like_sf
IPR002121, HRDC_dom
IPR027417, P-loop_NTPase
IPR032284, RecQ_Zn-bd
IPR018982, RQC_domain
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08072, BDHCT, 1 hit
PF16202, BLM_N, 1 hit
PF00270, DEAD, 1 hit
PF00271, Helicase_C, 1 hit
PF00570, HRDC, 1 hit
PF16124, RecQ_Zn_bind, 1 hit
PF09382, RQC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00487, DEXDc, 1 hit
SM00490, HELICc, 1 hit
SM00341, HRDC, 1 hit
SM00956, RQC, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46785, SSF46785, 1 hit
SSF47819, SSF47819, 1 hit
SSF52540, SSF52540, 2 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00614, recQ_fam, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00690, DEAH_ATP_HELICASE, 1 hit
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit
PS50967, HRDC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9I920-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEARAATNG GSGESQKLSN GEKSSQLEPG DVGNELLADI ELEEDDYLDV 
        60         70         80         90        100
VPPSPEEELP SFSPSVRNVS NIFKESPTDG RSAVHGTESE PELMAPKQPA 
       110        120        130        140        150
AEQDSSAEHA DKGLHLEQQL YSVMEDICKL VDAIPLHELT SISCAKELLQ 
       160        170        180        190        200
QRELRRKLLA DSGALNTNSV NGPRNWKACV QQDPSSRPGT PLCSGPGRGV 
       210        220        230        240        250
SSVGSTPKST NLPSVLSRTV NSSSFSTIRN QTLDKLDTSY SSKETDQEVI 
       260        270        280        290        300
CLEPAALPSP KVNGKGSTSL SRPSEASFNG SWCEKPTGRD SGNWRVPERP 
       310        320        330        340        350
TASTALKAQH TAPAGNPASG CWDVNDTDFD LDHFDIDDFD EGWEEAVAPE 
       360        370        380        390        400
AAPEAPPAPQ WQPLREGSAS LRCRLLAAAA GSAPGPHPTA PKSGCGISAK 
       410        420        430        440        450
SSSEPLVHNP AHERFRGMKF SHSEEMLKIF HRKFGLHSFR TNQLEAINAA 
       460        470        480        490        500
LLGEDCFILM PTGGGKSLCY QLPACVSAGV TVVISPLRSL IIDQVQKLKT 
       510        520        530        540        550
LDIASTYLTG DITDADASKT YMQLSKKDPI IKLLYVTPEK VCASNRLLSA 
       560        570        580        590        600
LENLYNRKLL ARFVIDEAHC VSQWGHDFRK DYKRLNMLRK KFHSVPMMAL 
       610        620        630        640        650
TATANPRVQK DIQNQLEMLK PQVFTMSFNR HNLKYDVLPK KPKKVAMDCL 
       660        670        680        690        700
EWIKKYHPHD SGIIYCLSRH ECDTTAAILQ KEGLAALAYH AGLTDSNRDL 
       710        720        730        740        750
VQKKWVNQEG CQVICATIAF GMGIDKPDVR YVIHASLPKS IEGYYQESGR 
       760        770        780        790        800
AGRDGEMSHC LLFYSYSDVT RLRRLILMEK DGNSHTRQTH FNNLYSMVHY 
       810        820        830        840        850
CENVVDCRRI QLLAYFGETD FNPNFCKDHP EVICDNCSRK KDYKSRNVTD 
       860        870        880        890        900
EVKSIIRFVQ QHCGQVGGIN GNRNTGSGRY TLNMMVDIFL GAKSAKIQSG 
       910        920        930        940        950
IFGKGAAYSR HNVERLFRKL VLDKILDEDL YITANDQAVA YVVLGEKAQA 
       960        970        980        990       1000
VLNGLLQVEF HETENASAIR KQRASVTKMS QREEMVKKCL GELTDTCKTL 
      1010       1020       1030       1040       1050
GKIFDVHYFN IFSTSTLKKI AETLSSDAEV LLQIDGVTED KLEKYGAEII 
      1060       1070       1080       1090       1100
KVMDKYSEWT TPEDAACQSV DTAPGSAGTP GSEEEAADDV VTSSYFGGNA 
      1110       1120       1130       1140       1150
NQRRKRKRLP NSGESKRKKT SSGGSQQFYS KGARYRRARR APGSRAAAPA 
      1160       1170       1180 
QSSALRGAGA RLGIMAPPKP SSRHFLQPSY AVL
Length:1,183
Mass (Da):130,294
Last modified:September 27, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iECB940035F08D117
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti112K → R in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti198R → Q in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti223S → G in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti253E → K in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti289R → K in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti319S → L in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti339F → L in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti351A → T in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti358A → P in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti399A → V in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti505S → A in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti556N → D in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti741I → V in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti746Q → H in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti839R → T in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti866V → M in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti893K → E in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti898Q → H in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti921V → F in BAA96742 (PubMed:10880455).Curated1
Sequence conflicti1087A → E in BAA96742 (PubMed:10880455).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ720413 mRNA Translation: CAG32072.1
AB040747 mRNA Translation: BAA96742.1

NCBI Reference Sequences

More...RefSeqi		NP_001007088.2, NM_001007087.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		415577

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		gga:415577

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720413 mRNA Translation: CAG32072.1
AB040747 mRNA Translation: BAA96742.1
RefSeqiNP_001007088.2, NM_001007087.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5LUTX-ray2.72A/B/C/D/E/F/G/H/I/J/K97-162[»]
SMRiQ9I920
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000013422

Proteomic databases

PaxDbiQ9I920

Genome annotation databases

GeneIDi415577
KEGGigga:415577

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		641

Phylogenomic databases

eggNOGiKOG0351, Eukaryota
InParanoidiQ9I920
OrthoDBi445763at2759

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9I920

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR012532, BDHCT
IPR032437, BLM_N
IPR011545, DEAD/DEAH_box_helicase_dom
IPR002464, DNA/RNA_helicase_DEAH_CS
IPR004589, DNA_helicase_ATP-dep_RecQ
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR010997, HRDC-like_sf
IPR002121, HRDC_dom
IPR027417, P-loop_NTPase
IPR032284, RecQ_Zn-bd
IPR018982, RQC_domain
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF08072, BDHCT, 1 hit
PF16202, BLM_N, 1 hit
PF00270, DEAD, 1 hit
PF00271, Helicase_C, 1 hit
PF00570, HRDC, 1 hit
PF16124, RecQ_Zn_bind, 1 hit
PF09382, RQC, 1 hit
SMARTiView protein in SMART
SM00487, DEXDc, 1 hit
SM00490, HELICc, 1 hit
SM00341, HRDC, 1 hit
SM00956, RQC, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
SSF47819, SSF47819, 1 hit
SSF52540, SSF52540, 2 hits
TIGRFAMsiTIGR00614, recQ_fam, 1 hit
PROSITEiView protein in PROSITE
PS00690, DEAH_ATP_HELICASE, 1 hit
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit
PS50967, HRDC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBLM_CHICK
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9I920
Secondary accession number(s): Q5ZJM1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: September 27, 2017
Last modified: December 2, 2020
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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