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UniProtKB - Q9I703 (BAUD_PSEAE)
Protein
Probable GABA permease
Gene
bauD
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
Involved in the degradation of beta-alanine.
1 PublicationGO - Molecular functioni
- gamma-aminobutyric acid transmembrane transporter activity Source: InterPro
GO - Biological processi
- beta-alanine biosynthetic process Source: PseudoCAP
Keywordsi
Biological process | Amino-acid transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Probable GABA permeaseAlternative name(s): 4-amino butyrate transport carrier Gamma-aminobutyrate permease |
Gene namesi | Name:bauD Synonyms:gabP Ordered Locus Names:PA0129 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA0129 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 27 – 47 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 48 – 68 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 105 – 125 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 127 – 147 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 163 – 183 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 211 – 231 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 250 – 270 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 296 – 316 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 345 – 365 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 368 – 388 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 413 – 433 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 438 – 458 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Disruption phenotypei
Cells lacking this gene grow normally on putrescine, cadaverine, and GABA, but growth on beta-alanine is completely abolished.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000428973 | 1 – 475 | Probable GABA permeaseAdd BLAST | 475 |
Proteomic databases
PaxDbi | Q9I703 |
Expressioni
Inductioni
Activated by BauR.1 Publication
Family & Domainsi
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
HOGENOMi | CLU_007946_9_3_6 |
InParanoidi | Q9I703 |
OMAi | PMTIAIQ |
PhylomeDBi | Q9I703 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS IPR011265, GABA_permease |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
TIGRFAMsi | TIGR01773, GABAperm, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9I703-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKVVLASQL PNKRNASLAP GLKQRHVTML SIAGVIGAGL FVGSGHAIAA
60 70 80 90 100
AGPAALLAYL IAGTLVVLVM RMLGEMAVAS PDTGSFSTYA DRSIGRWAGF
110 120 130 140 150
TIGWLYWWFW VLVIPLEAIA AAAILNAWFP AIDTWIFALA VTFLLTVTNL
160 170 180 190 200
FSVARYGEFE FWFALLKVIA IIAFIVLGAV AIVGGLPERE VSGLSSLMAS
210 220 230 240 250
HGGFVPNGYG AVLGALLTTM FSFMGTEIVT IAAAESKDPA KQITRATNSV
260 270 280 290 300
IWRIGLFYLV SIFIVISIVP WNDPLLIQVG SYQRALELLD IPHAKLIVDL
310 320 330 340 350
VVLVAVASCL NSAIYTSSRM VFSLAKRGDA PSVLKLTNTA HVPRPAVLAS
360 370 380 390 400
TAVGFLTTIV NYFAPEKVFT FLLASSGAVA LLVYLVIAVA QLRMRKQLQA
410 420 430 440 450
SGQPIEFRMW LYPWLTWAVI LFIVAALSIM LIMPEHRHEV FATALLTIFT
460 470
VCLGLLNARR KPRLGEDYAG KTARV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG03519.1 |
PIRi | B83631 |
RefSeqi | NP_248819.1, NC_002516.2 WP_003083784.1, NZ_QZGE01000015.1 |
Genome annotation databases
EnsemblBacteriai | AAG03519; AAG03519; PA0129 |
GeneIDi | 880844 |
KEGGi | pae:PA0129 |
PATRICi | fig|208964.12.peg.134 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE004091 Genomic DNA Translation: AAG03519.1 |
PIRi | B83631 |
RefSeqi | NP_248819.1, NC_002516.2 WP_003083784.1, NZ_QZGE01000015.1 |
3D structure databases
SMRi | Q9I703 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 287.DR97_3086 |
Proteomic databases
PaxDbi | Q9I703 |
Genome annotation databases
EnsemblBacteriai | AAG03519; AAG03519; PA0129 |
GeneIDi | 880844 |
KEGGi | pae:PA0129 |
PATRICi | fig|208964.12.peg.134 |
Organism-specific databases
PseudoCAPi | PA0129 |
Phylogenomic databases
HOGENOMi | CLU_007946_9_3_6 |
InParanoidi | Q9I703 |
OMAi | PMTIAIQ |
PhylomeDBi | Q9I703 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS IPR011265, GABA_permease |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
TIGRFAMsi | TIGR01773, GABAperm, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | BAUD_PSEAE | |
Accessioni | Q9I703Primary (citable) accession number: Q9I703 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 14, 2014 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 23, 2022 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families